Association between volume of lung damage and endoplasmic reticulum stress expression among severe COVID-19 ICU patientsMedicine Original Research Published on 2024-06-112024-09-05 Journal: Frontiers in Medicine [Category] update2024, [키워드] acute respiratory distress syndrome COVID-19 endoplasmic reticulum stress humans Inflammation intensive care unit interleukin-6 Organ failure [DOI] 10.3389/fmed.2024.1368031 PMC 바로가기 [Article Type] Medicine Original Research
Extracellular Vesicles in Lung Cancer: Implementation in Diagnosis and Therapeutic PerspectivesReview Published on 2024-05-222024-09-05 Journal: Cancers [Category] update2024, [키워드] BALF EVs liquid biopsy lung cancer NSCLC Organ failure Personalized medicine SCLC [DOI] 10.3390/cancers16111967 PMC 바로가기 [Article Type] Review
Proposed Framework for Conducting Clinically Relevant Translational Biomarker Research for the Diagnosis, Prognosis and Management of SepsisReview Published on 2024-01-302024-09-05 Journal: Diagnostics [Category] update2024, [키워드] Antibiotics antimicrobial resistance Biomarker Infection organ dysfunction Organ failure Sepsis Septic shock systemic inflammation response [DOI] 10.3390/diagnostics14030300 PMC 바로가기 [Article Type] Review
SARS-CoV-2-associated organs failure and inflammation: a focus on the role of cellular and viral microRNAsarticle Published on 2023-08-092024-09-05 Journal: Virology Journal [Category] update2024, [키워드] COVID-19 Inflammation microRNA Organ failure SARS-CoV-2 [DOI] 10.1186/s12985-023-02152-6 PMC 바로가기 [Article Type] article
Recent advances in pre-conditioned mesenchymal stem/stromal cell (MSCs) therapy in organ failure; a comprehensive review of preclinical studiesarticle Published on 2023-06-072024-09-05 Journal: Stem Cell Research & Therapy [Category] update2024, [키워드] hypoxia Mesenchymal stem/stromal cells (MSCs) Organ failure Pre-conditioning transplantation [DOI] 10.1186/s13287-023-03374-9 PMC 바로가기 [Article Type] article
The value of EEG attenuation in the prediction of outcome in COVID-19 patientsArticle Published on 2022-11-012022-11-16 Journal: Neurological Sciences [Category] SARS, 유전자 메커니즘, [키워드] biomarkers of inflammation Brain imaging brain involvement Cohort collected consecutive patients correlated correlation COVID-19 pandemic COVID-19 patient COVID-19 patients EEG EEG attenuation EEG background EEG suppression Encephalopathy epileptiform evaluated heterogeneous Hypoxemia identify in-hospital mortality lesion mechanism non-survivor Non-survivors Occurrence Organ failure outcome PaO patients performed Prevalence prevalent Prognosis recorded reduced reported SARS-CoV-2 SARS-COV-2 infection significantly significantly lower suppressed [DOI] 10.1007/s10072-022-06354-8 PMC 바로가기
Vitamin D deficiency is Associated with Increased Risk of Delirium and Mortality among Critically Ill, Elderly Covid-19 PatientsResearch article Published on 2022-11-012022-10-05 Journal: Complementary therapies in medicine [Category] COVID19(2023년), SARS, 바이오마커, [키워드] adjusted association baseline blood pressure collected data Comorbidities confounders coronavirus disease COVID-19 COVID-19 mortality COVID-19 patients Critically ill deficiency delirium demographic characteristics elderly Elderly patient Face mask higher risk Hospital admission Hospitalization Hospitalized ICU ICU admission Ill IMV incidence increase in Increased increased risk information intensive care Invasive mechanical ventilation Laboratory parameters less lower risk mechanical ventilation medications Mortality Older Organ failure outcome Patient positive prevalent propofol Prospective Study Result risk SARS-CoV-2 serum single center Study participants Treatment Vitamin D vitamin D deficiency vitamin D level vitamin D sufficiency was done were recorded [DOI] 10.1016/j.ctim.2022.102855 [Article Type] Research article
Antioxidant, Anti-inflammatory, and Immunomodulatory Roles of Nonvitamin Antioxidants in Anti-SARS-CoV-2 TherapyArticle Published on 2022-10-132022-11-15 Journal: Journal of medicinal chemistry [Category] COVID19(2023년), SARS, 바이오마커, 치료제, [키워드] ACE2 receptor Activation activities alleviate Alleviating alveolar antioxidant antiviral role conformational change COVID-19 Cytokine storm Dipeptidyl peptidase 4 Direct dosage Endothelium favor furin Helicase host receptor hyperinflammation Illness severity immunogenic Inflammatory Inflammatory responses influences membranes Organ failure oxidative stress Papain-like protease pathology pathway protease reactive oxygen specy Receptor binding domain Replication risk RNA-dependent RNA polymerase role serine 2 the spike protein transmembrane vicious cycle viral spike protein [DOI] 10.1021/acs.jmedchem.2c01134 PMC 바로가기
Effect of a diet based on Iranian traditional medicine on inflammatory markers and clinical outcomes in COVID-19 patients: A double-blind, randomized, controlled trialResearch article Published on 2022-10-012022-10-05 Journal: European Journal of Integrative Medicine [Category] 바이오마커, 임상, [키워드] acute respiratory syndrome Antiviral treatment appear approved baseline characteristics C-reactive protein cause caused Cicer Cicer arietinum Clinical outcome clinical trial Combination conducted control group cough COVID-19 COVID-19 patient COVID-19 patients demographics develop diagnosis of COVID-19 diet double-blind education Effect effective Efficacy and safety Ficus ficus carica headache help Hospitalization Inflammatory biomarker Inflammatory marker Intervention intervention group Iran Laboratory life-threatening Medicine Ministry of Health myalgia no significant difference Organ failure Patient randomized clinical trial randomized, controlled trial regimen Research Result Reza Safflower Sample size SARS-CoV-2 significant difference significantly lower SPSS software statistical analysis supportive care Symptom Symptoms Tehran Traditional traditional Persian medicine Treatment treatment period Treatment protocol variables virus Vitis Vitis vinifera weakness while [DOI] 10.1016/j.eujim.2022.102179 [Article Type] Research article
Identification of COVID-19 patients at risk of hospital admission and mortality: a European multicentre retrospective analysis of mid-regional pro-adrenomedullinObservational Study Published on 2022-08-282022-10-05 Journal: Respiratory Research [Category] SARS, 바이오마커, 임상, [키워드] age Analysis assessment Bacterial infections Classifier collected Combination COVID-19 patient CRP death demographics Department discharge Emergency emergency department Europe European examined failure hospital Hospital admission hospitalisation identification identify IMPROVE in viral increased risk infected with SARS-CoV-2 Infection Inflammatory biomarker International LDH mid-regional pro-adrenomedullin Mortality MR-proADM multicenter multicentre Organ failure outcome Patient patients performed presenting previous study primary endpoint prognostic Prognostic factor random Retrospective analysis risk RT-qPCR Safe SARS-CoV-2 SARS-COV-2 infection secondary care Sepsis Septic shock SOFA SOFA score the patient Treatment utility was performed [DOI] 10.1186/s12931-022-02151-1 PMC 바로가기 [Article Type] Observational Study