From Detection to Protection: Antibodies and Their Crucial Role in Diagnosing and Combatting SARS-CoV-2Review Published on 2024-04-252024-09-05 Journal: Vaccines [Category] update2024, [키워드] Antibody-dependent enhancement convalescent plasma COVID-19 diagnostic Immunotherapy Long COVID neutralizing monoclonal antibodies Omicron subvariants original antigenic sin SARS-CoV-2 SARS-CoV-2-specific antibodies serological assays Vaccine variants of concern (VOC) [DOI] 10.3390/vaccines12050459 PMC 바로가기 [Article Type] Review
Back to the Future: Immune Protection or Enhancement of Future CoronavirusesReview Published on 2024-03-192024-09-05 Journal: Microorganisms [Category] update2024, [키워드] Antibody-dependent enhancement conserved T-cell epitopes COVID-19 human coronaviruses original antigenic sin SARS-CoV-2 [DOI] 10.3390/microorganisms12030617 PMC 바로가기 [Article Type] Review
Potential immune evasion of the severe acute respiratory syndrome coronavirus 2 Omicron variantsImmunology Review Published on 2024-02-232024-09-05 Journal: Frontiers in immunology [Category] update2024, [키워드] Hybrid immunity immune evasion Omicron variant original antigenic sin SARS-CoV-2 [DOI] 10.3389/fimmu.2024.1339660 PMC 바로가기 [Article Type] Immunology Review
Immunological imprinting shapes the specificity of human antibody responses against SARS-CoV-2 variantsArticle Published on 2024-01-092024-09-05 Journal: medRxiv [Category] update2024, [키워드] antibodies B cells immune evasion immune imprinting mRNA vaccines Omicron BA.5 original antigenic sin SARS-CoV-2 viral evolution XBB.1.5 [DOI] 10.1101/2024.01.08.24301002 PMC 바로가기 [Article Type] Article
Cross protection to SARS-CoV-2 variants in hamsters with naturally-acquired immunityarticle Published on 2023-07-282024-09-05 Journal: Virology Journal [Category] update2024, [키워드] Cross-immunity hamster original antigenic sin SARS-CoV-2 variants of concern [DOI] 10.1186/s12985-023-02136-6 PMC 바로가기 [Article Type] article
SARS-CoV-2 infections elicit higher levels of original antigenic sin antibodies compared with SARS-CoV-2 mRNA vaccinationsArticle Published on 2022-10-182022-11-15 Journal: Cell Reports [Category] COVID19(2023년), SARS, 진단, [키워드] acute respiratory syndrome antibodies antibody antigenic assays boost coronavirus CP: Immunology cross-react determine elicit Health care worker human coronavirus human coronaviruses Infection magnitude mRNA mRNA vaccination mRNA vaccines original antigenic sin participant proportion reactive responses SARS-CoV-2 SARS-COV-2 infection specificity vaccination [DOI] 10.1016/j.celrep.2022.111496 PMC 바로가기
Pre-Pandemic Cross-Reactive Immunity against SARS-CoV-2 among Central and West African PopulationsArticle Published on 2022-10-142022-11-15 Journal: Viruses [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] Africa African antibody Antigen antigenic Asian blood donor collected control sample coronavirus 2 coronavirus disease-2019 COVID-19 COVID-19 pandemic CoviDiag detect evaluate France French highlighting human population Hypothesis identify IgG Immunity incidence rate investigated morbidity natural immunity neutralizing antibody original antigenic sin pandemic Population pre-existing immunity Prevalence Protective Region reported respiratory SARS-CoV-2 SARS-CoV-2 protein sera statistically significant difference tested virus West [DOI] 10.3390/v14102259 PMC 바로가기
A comprehensive review of BBV152 vaccine development, effectiveness, safety, challenges, and prospectsArticle Published on 2022-09-132022-11-16 Journal: Frontiers in Immunology [Category] SARS, 변종, [키워드] Administered Adults age antigenic approved booster children clinical development comparable country CoV COVID-19 pandemic COVID-19 severity disease Effectiveness Efficacy Emergency use Emergency use authorization generate geometric mean titer group Healthcare system Heterologous heterologous prime and boost vaccines heterologous prime-boost immune response inactivated Inactivated vaccine inactivated virus adjuvanted vaccine increase in India induce Like memory B morbidity Mortality neutralization neutralization titer original antigenic sin over pandemic pediatric phase Population prime and boost reactogenicity reduce reduction in robust safety profile SARS – CoV – 2 SARS-CoV-2 variant seroconversion rate symptomatic COVID-19 disease synergy T-cell responses TLR7/8 vaccinated individuals vaccination Vaccine vaccine challenges Vaccine development vaccine dose Vaccines variants of concern variants of concern (VOCs) virus VOCs waning immunity [DOI] 10.3389/fimmu.2022.940715 PMC 바로가기
mRNA-1273 or mRNA-Omicron boost in vaccinated macaques elicits similar B cell expansion, neutralizing responses, and protection from OmicronArticle Published on 2022-03-252023-06-16 Journal: Cell [Category] COVID19(2023년), MERS, SARS, [키워드] antibody B cells boost COVID-19 immune memory mRNA vaccine omicron original antigenic sin SARS-CoV-2 T cells [DOI] 10.1016/j.cell.2022.03.038 PMC 바로가기 [Article Type] Article
Beta RBD boost broadens antibody-mediated protection against SARS-CoV-2 variants in animal modelsArticle Published on 2021-10-232022-10-31 Journal: Cell Reports Medicine [Category] COVID-19, MERS, SARS, [키워드] Abstract Against animal challenge animal model Antibody Response antigenic antigens Beta Beta variant boost booster Cell Critical cross-neutralizing antibody response disease Efficacy elicit Evidence Heterologous Heterotypic heterotypic boost Humoral immunity immunization immunized Infection K18-hACE2 mice macaque memory B neutralizing antibody Neutralizing antibody response original antigenic sin outcome pandemic passive immunization passive transfer plasma PROTECT Protein RBD Receptor binding domain reduced response restored rhesus macaque SARS-CoV-2 SARS-CoV-2 variant single dose Spread subsequent Vaccine Vaccines variant variants of concern VoC VOCs widespread [DOI] 10.1016/j.xcrm.2021.100450 PMC 바로가기 [Article Type] Article