Physiological jump in erythrocyte redox potential during Plasmodium falciparum development occurs independent of the sickle cell traitarticle Published on 2022-12-312024-09-01 Journal: Redox Biology [Category] 말라리아, [키워드] Erythrocyte redox potential Genetically encoded redox sensors glutathione Oxidation Plasmodium falciparum infected red blood cells reduction roGFP2 secretory pathway sickle cell trait [Article Type] article
Raman Fingerprints of the SARS-CoV-2 Delta Variant and Mechanisms of Its Instantaneous Inactivation by Silicon Nitride BioceramicsSARS-CoV-2 Delta 변이체의 라만 지문과 질화규소 바이오세라믹에 의한 즉각적인 비활성화 메커니즘Article Published on 2022-08-122022-09-11 Journal: ACS Infectious Diseases [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] Amino acid arginine B.1.617.2 collected Delta delta variant effective environmental sanitation fingerprint fraction hydrophobic hydrophobic interaction hydrophobic interactions inactivation Inorganic compound instantaneous instantaneous virus inactivation Japanese Lineage marker mechanism methionine molecular Mutation mutations Nitride Occurrence Oxidation Particle Protein purine purines pyrimidines Raman spectroscopy reaction receptor recorded referred to residue residues RNA Safe SARS-CoV-2 secondary structure silicon silicon nitride. sulfur the SARS-CoV-2 tyrosine variant viral inactivation virion virions virus [DOI] 10.1021/acsinfecdis.2c00200 PMC 바로가기 [Article Type] Article
In vitro potential antiviral SARS-CoV-19- activity of natural product thymohydroquinone and dithymoquinone from Nigella sativaNigella sativa의 천연물 티모하이드로퀴논 및 디티모퀴논의 시험관 내 잠재적 항바이러스 SARS-CoV-19- 활성Article Published on 2022-03-012022-09-11 Journal: Bioorganic chemistry [Category] SARS, 치료제, [키워드] acute respiratory distress acute respiratory distress syndrome Anti-SARS-CoV-2 Activity Antiviral antiviral activity assist calculated can be used Compound compounds Concentration coronavirus COVID-19 cytotoxicity Dithymoquinone essential oil Hydrothymoquinone IC50 Immunity in vitro MTT Nigella Nigella Sativa Oxidation protocol respiratory distress SARSCoV-19 selectivity index syndrome thymoquinone Treatment Vitamin E Zinc [DOI] 10.1016/j.bioorg.2021.105587 PMC 바로가기 [Article Type] Article
Horseradish peroxidase-triggered direct in situ fluorescent immunoassay platform for sensing cardiac troponin I and SARS-CoV-2 nucleocapsid protein in serum혈청에서 심장 트로포닌 I 및 SARS-CoV-2 뉴클레오캡시드 단백질을 감지하기 위한 홀스래디쉬 퍼옥시다제 트리거 직접 제자리 형광 면역분석 플랫폼Article Published on 2022-02-152022-09-11 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 치료기술, 치료법, [키워드] adjusted analogue antigens applied Biomarker cardiac cardiac troponin Cardiac troponin I diagnostics Direct dynamic range ELISA enzyme-linked immunosorbent enzyme-linked immunosorbent assay evaluate exhibited fluorescent Fluorescent immunoassay generate group Horseradish horseradish peroxidase immunoassay investigated limit of detection mechanism N-protein nitrogen nucleocapsid protein Oxidation p-Phenylenediamine PEI peroxidase platform Protein Rapid reported SARS-CoV-2 N protein SARS-CoV-2 nucleocapsid SARS-CoV-2 nucleocapsid protein scavenger serum troponin I Wavelength-tunable. [DOI] 10.1016/j.bios.2021.113823 PMC 바로가기 [Article Type] Article
Cysteamine with In Vitro Antiviral Activity and Immunomodulatory Effects Has the Potential to Be a Repurposing Drug Candidate for COVID-19 Therapy시험 관내 항 바이러스 활성 및 면역 조절 효과를 갖는 시스 티민은 COVID-19 요법에 대한 용도의 약물 후보가 될 가능성이있다.Article Published on 2021-12-242022-08-31 Journal: Cells [Category] SARS, 신약개발, 치료제, [키워드] activity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Anti-inflammatory anti-inflammatory effect Antiviral antiviral action Antiviral effect antiviral effects applied assays Bacteria blood sample Blood samples calu-3 cells candidate caused coronavirus coronavirus disease coronavirus disease-2019 COVID-19 COVID-19 patients COVID-19 therapy CPE cystamine cysteamine Cytopathic effect cytopathic effects decrease demonstrated determine Disulfide drug Drug repurposing Effect IFN-γ immune response immunomodulatory effects in vitro independent independent of investigated modulate Oxidation pandemic parasites Potential repurposing respiratory SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus significantly the SARS-CoV-2 therapy for COVID-19 these compound these compounds Treatment Vero E6 VERO E6 cells Viral viruses [DOI] 10.3390/cells11010052 PMC 바로가기 [Article Type] Article
Oxidative Stress and Pathogenesis in Malaria말라리아의 산화 스트레스와 병인학Article Published on 2021-11-302024-08-08 Journal: Frontiers in Cellular and Infection Microbiology [Category] 말라리아, [키워드] cerebral malaria malaria Oxidation oxidative stress Pathogenesis Plasmodium falciparum Plasmodium vivax reactive oxygen species [DOI] 10.3389/fcimb.2021.768182 PMC 바로가기
Transformation of antiviral ribavirin during ozone/PMS intensified disinfection amid COVID-19 pandemicCOVID-19 전염병 속에서 소독을 강화한 오존/PMS 중 항바이러스 리바비린의 변환Article Published on 2021-10-102022-09-11 Journal: The Science of the total environment [Category] SARS, 치료제, [키워드] accelerated accounted Advanced oxidation process amide Antiviral Bicarbonate bromide chloride Concentration condition coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic Degradation Disinfection dominant dosage ecosystem Efficiency ENhance followed by Health hospital hydroxyl hydroxyl group hydroxyl groups investigated Iodide methanol organic matter Oxidation Oxidation by-products Ozonation Ozone Peroxymonosulfate potential risk rate constant reaction rate reduced released ribavirin risk significantly higher Spread transformation wastewater [DOI] 10.1016/j.scitotenv.2021.148030 PMC 바로가기 [Article Type] Article
7-Ketocholesterol: Effects on viral infections and hypothetical contribution in COVID-197-케토콜레스테롤: 바이러스 감염에 미치는 영향 및 COVID-19에 대한 가설적 기여Review Published on 2021-09-012022-09-11 Journal: The Journal of steroid biochemistry and molecular [Category] MERS, 바이오마커, 치료제, [키워드] 7-Ketocholesterol activate activities activity acute respiratory distress acute respiratory distress syndrome adjuvant adjuvant therapies adjuvant therapy affected Age-related macular degeneration alveolar cells Alzheimer's disease Anti-viral antiviral activity Apoptosis appear assumed auto-oxidation autophagy Biomarker cancers cardiovascular diseases cell death cholesterol chronic inflammatory bowel diseases concentrations contribute contributing to COVID-19 COVID-19 patients Deleterious density disease Diseases Effect food hypothetical Inflammatory bowel disease inflammatory bowel diseases involved macular degeneration outcome Oxidation oxidized oxysterol Oxysterols pathophysiology pro-inflammatory produced promote provided recent respiratory distress Respiratory distress syndrome resulting SARS-CoV-2 serum shown side chain significantly suggested syndrome toxic effect toxic effects Viral Viral diseases viral infection [DOI] 10.1016/j.jsbmb.2021.105939 PMC 바로가기 [Article Type] Review
Multiplexed Magnetofluorescent Bioplatform for the Sensitive Detection of SARS-CoV-2 Viral RNA without Nucleic Acid Amplification핵산 증폭 없이 SARS-CoV-2 바이러스 RNA의 민감한 검출을 위한 다중 자기형광 바이오플랫폼Article Published on 2021-08-172022-09-11 Journal: Analytical Chemistry [Category] SARS, 치료기술, 치료제, [키워드] acid Biotin clinical sample clinical samples complementary conditions COVID-19 pandemic death detect detection dynamic range fluorescent Genes genetic material gold gold standard help Hepatitis hepatitis C horseradish peroxidase linear loci magnetic bead Magnetic beads measles mitigate N genes Nasopharyngeal swab nasopharyngeal swabs Nile ORF1a outbreak Oxidation Patient patients peroxidase phenylenediamine point of care probe Rapid reached related virus reporter RNA RT-qPCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA SARS-CoV-2 virus sensitive sensitivity Sensitivity and specificity subjects the SARS-CoV-2 total RNA Viral RNA viruses were used West [DOI] 10.1021/acs.analchem.1c01950 PMC 바로가기 [Article Type] Article
Reductive Power Generated by Mycobacterium leprae Through Cholesterol Oxidation Contributes to Lipid and ATP Synthesis마이코박테리움 레프라에 의한 콜레스테롤 산화로 생성된 환원력은 지질 및 ATP 합성에 기여한다.Original Research Published on 2021-07-282024-07-29 Journal: Frontiers in Cellular and Infection Microbiology [Category] 한센병, [키워드] 3β-HSD cholestenone cholesterol Mycobacterium leprae Oxidation PDIM PGL-I reductive power [DOI] 10.3389/fcimb.2021.709972 PMC 바로가기 [Article Type] Original Research