Preclinical safety evaluation and tracing of human mesenchymal stromal cell spheroids following intravenous injection into cynomolgus monkeysResearch article Published on 2022-10-012022-10-05 Journal: Biomaterials [Category] Coronavirus, 비임상, [키워드] addressed administration ambient Blood blood vessel Cell death demonstrated dissociate Efficacy feasible Host hypoxic condition injection intravenous Intravenous injection less lung Mesenchymal stem cells mice Monkey MSC MSCs multiple sclerosis occurred Osteoarthritis physiological change Preclinical promote retention Safe Safety Single Cell small blood vessel small vessel Spheroid Stress stromal cell survival viability wound healing [DOI] 10.1016/j.biomaterials.2022.121759 [Article Type] Research article
Physiological Effects of Wearing N95 Respirator on Medical Staff During Prolong Work Hours in Covid-19 DepartmentsObservational Study Published on 2022-06-012022-10-05 Journal: Journal of occupational and environmental medicine [Category] 임상, [키워드] abnormality change changes in Department determine Effect Gas exchange Healthcare professional healthcare worker hour increase in medical staff not differ oxygen saturation performed physiological change plasma Prolonged prospective observational study provoke Respirator subject wearing work [DOI] 10.1097/JOM.0000000000002542 PMC 바로가기 [Article Type] Observational Study
Real-time infection prediction with wearable physiological monitoring and AI to aid military workforce readiness during COVID-19COVID-19 동안 군사 인력 준비를 돕기위한 웨어러블 생리적 모니터링 및 AI를 통한 실시간 감염 예측Article Published on 2022-03-082022-09-01 Journal: Scientific Reports [Category] MERS, SARS, 진단, 치료기술, [키워드] Algorithm AUC average barrier capture COVID-19 COVID-19 pandemic Defense Department diagnostic diagnostic testing early infection feasibility Garmin healthy Impact impacts implementation increased risk Infection infection risk Infectious diseases Isolation machine learning maintenance observé physiological physiological change positive Predictive Predictive model predictive models reduce risk SARS-CoV-2 service Threats Transmission United State United States [DOI] 10.1038/s41598-022-07764-6 PMC 바로가기 [Article Type] Article
Pathophysiological and molecular considerations of viral and bacterial infections during maternal-fetal and -neonatal interactions of SARS-CoV-2, Zika, and Mycoplasma infectious diseasesSARS-CoV-2, Zika 및 Mycoplasma 전염병의 산모-태아 및 신생아 상호작용 중 바이러스 및 세균 감염의 병태생리학적 및 분자적 고려Article Published on 2022-01-012022-09-11 Journal: Biochimica et biophysica acta. Molecular basis of [Category] MERS, SARS, 바이오마커, 진단, [키워드] addition Admission age Anomaly Bacteria Bacterial infection Bacterial infections birth defects Case report case reports Case series caused cellular Characteristics children COVID-19 COVID-19 disease death disease disease severity during pregnancy elevated epidemiological data epidemiological studies Epidemiological study example fetus focus higher risk Hospitalized increase increased risk Infant Infants Infection Infectious disease intensive care intensive care unit admission Interaction macroscopic manifestation Maternal Maternal-fetal interphase mechanical ventilation mechanism microcephaly molecular mother Mycoplasma Neonate Neonates nonpregnant not increased Older outcomes pandemic Particular pathogen Pathogens pathophysiological physiological change Physiological changes Pregnancy pregnant women progression risk SARS-CoV-2 SARS-CoV-2 virus severe COVID-19 disease susceptibility susceptibility to infection susceptible the SARS-CoV-2 virus Viral virus infection viruses with COVID-19 women Zika Zika virus infection ZIKV [DOI] 10.1016/j.bbadis.2021.166285 PMC 바로가기 [Article Type] Article
Sleep and COVID-19. A Case Report of a Mild COVID-19 Patient Monitored by Consumer-Targeted Sleep Wearables수면과 코로나19. 소비자 대상 수면 웨어러블로 모니터링한 경증 COVID-19 환자의 사례 보고서Case Reports Published on 2021-11-282022-09-10 Journal: Sensors (Basel, Switzerland) [Category] MERS, SARS, 치료기술, 치료제, [키워드] Affect affected bidirectional Biomarker clinical care Clinicians consumer sleep wearables continuous monitoring COVID-19 COVID-19 progression Deprivation detect Disease progression evaluate IMPROVE Infection intensive care management Novel coronavirus offer pandemic pathologic Patient Patients at Home physician physiological change Physiological changes public health public health services report SARS-CoV-2 Sleep sleep deprivation sleep disorders sleep time Spread Total treat TST wake Wuhan Wuhan, China [DOI] 10.3390/s21237944 PMC 바로가기 [Article Type] Case Reports
Functional Effects of Cardiomyocyte Injury in COVID-19COVID-19에서 심근세포 손상의 기능적 효과Cellular Response to Infection Published on 2021-10-202022-09-10 Journal: Journal of Virology [Category] MERS, 유전자 메커니즘, [키워드] absence acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Affect Analysis Blood cardiac disease Cardiomyocytes Cell clinical Clinical data Clinical finding Clinical findings Comorbidities Comorbidity Computational biology contractile contractile apparatus coronavirus COVID-19 COVID-19 patient COVID-19 patients Culture decrease decreased expression develop disease disorganization dysfunction echocardiography Effect elevated Elevation expression Extracellular healthy heart heart disease heart tissue hearts hospitalized patient hospitalized patients identify IL-1β IL-10 IL-1β IL-6 increase infect Infection Injury interleukin Interleukins Laboratory machine learning mechanism Mount Sinai Mount Sinai Health System mRNA multinucleated cells multiple organs NL63 observation Patient physiological physiological change physiological effect physiological effects pluripotent stem cell Protein reduced respiratory resulting SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus subject subset suppresse System Treatment Trigger triggers troponin troponin I underlie ventricular ventricular ejection Viral viral infection virus virus infection [DOI] 10.1128/JVI.01063-21 PMC 바로가기 [Article Type] Cellular Response to Infection
Women’s Lives Matter—The Critical Need for Women to Prioritize Optimal Physical Activity to Reduce COVID-19 Illness Risk and SeverityReview Published on 2021-09-292022-10-30 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] activity Affect benefit caused Community COVID-19 COVID-19 illness COVID-19 pandemic effective engage exercise Health health and wellness healthcare help illness include individual Infectious disease Intervention lockdown measure Mental morbidity and mortality nonpharmacological interventions pandemic performed physical physical activity (PA) physiological change Prevent preventive healthcare problem Psychological distress reduce risk risk mitigation Safe social distancing Spread the disease vaccination vaccination against COVID-19 women women’s health [DOI] 10.3390/ijerph181910271 PMC 바로가기 [Article Type] Review
Influence of the Human Development Index on the Maternal–Perinatal Morbidity and Mortality of Pregnant Women with SARS-CoV-2 Infection: Importance for Personalized Medical CareArticle Published on 2021-08-172022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] 1:1 association case-control study Comorbidities component conducted consequence Coronavirus disease-19 (COVID-19) country COVID-19 COVID-19 severity described enrolled gestation Human Development Index human development index (HDI) hypertensive ICU admission Importance independent risk factor Infection influence maternal–perinatal morbidity and mortality maternal–perinatal outcomes morbidity morbidity and mortality Mortality need for oxygen obesity Obstetric occur outcomes pandemic participant Patient physiological change Pregnancy pregnant women produced recent Research risk factor SARS-CoV-2 SARS-COV-2 infection SARV-CoV-2 tertiary care centers therapy women [DOI] 10.3390/jcm10163631 PMC 바로가기 [Article Type] Article
The Involvement of MicroRNAs in SARS-CoV-2 Infection Comorbid with HIV-Associated PreeclampsiaHIV 관련 자간전증을 동반한 SARS-CoV-2 감염에서 MicroRNA의 관련성Review Published on 2021-04-132022-09-11 Journal: Current hypertension reports [Category] SARS, 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Anti-viral coronavirus Critical demonstrated Diseases Disruption downregulate dysregulated Epigenetic Evidence evidence of expression foundation Health HIV HIV-1 HIV-1 infection Host host miRNA Human Human immunodeficiency virus hypertension immunodeficiency immunodeficiency virus implicated in silico in viral Infection investigated involved Involvement Maternal mechanism microRNA MicroRNAs miRNA miRNAs physiological physiological change preeclampsia Pregnancy pregnant women prevalent Protein provided recent Regulatory Research SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus Side-effect silico studies South Africa synergy therapeutic viral infections women [DOI] 10.1007/s11906-021-01138-5 PMC 바로가기 [Article Type] Review
Laboratory Effects of COVID-19 Infection in Pregnant Women and Their Newborns: A Systematic Review and Meta-AnalysisGlobal Women's Health Published on 2021-04-132022-10-31 Journal: Frontiers in Global Women's Health [Category] COVID-19, [키워드] acute respiratory syndrome Admission antibody transfer article authors Blood blood assay Care complications conducted coronavirus correlated COVID-19 COVID-19 pandemic COVID-19 virus CRP database Digital Effect elevated eligibility English English language evaluate the effect Evidence excluded Generalized Google Scholar hemoglobin Identifier identify IgG/IgM antibody Infant Laboratory laboratory-confirmed lactate dehydrogenase less Maternal Meta-analysis mother Neonatal neonatal sepsis Neonate Neonates neutrophil neutrophil count object passive immunity Patient physiological change Placenta Platelet Pregnancy pregnant pregnant women Preterm birth procalcitonin procalcitonin level R code Research Respiratory pathogens review risk SARS-CoV-2 SARS-CoV-2 pandemic searched selected Sepsis the disease Transmission vertical transmission with COVID-19 [DOI] 10.3389/fgwh.2021.647072 PMC 바로가기 [Article Type] Global Women's Health