Plasma cell – Communicable Diseases Research

The long term vaccine-induced anti-SARS-CoV-2 immune response is impaired in quantity and quality under TNFα blockade

장기간의 백신 유발 항SARS-CoV-2 면역 반응은 TNFα 차단으로 인해 양과 질이 저하됩니다.

Article

Published on 2022-12-012022-11-15
Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 백일해, 변종, 진단, 파상풍,

Immune response to SARS-CoV-2 vaccination in relation to peripheral immune cell profiles among patients with multiple sclerosis receiving ocrelizumab

오크렐리주맙을 투여받는 다발성 경화증 환자의 말초 면역 세포 프로필과 관련된 SARS-CoV-2 백신 접종에 대한 면역 반응

Article

Published on 2022-09-012022-09-12
Journal: Journal of neurology, neurosurgery, and psychiatry [Category] COVID19(2023년), MERS, SARS, 진단,

[키워드] adverse event analysed antibodies antibody B cell B cell subset baseline Blood Cell-mediated immunity Clinical data Clinical effect clinical trial correlated courses effective facilitate Follow-up humoral immune response identify IFN-γ IgM Immune cell immune response Immunocompromised patient Immunomodulatory therapies interferon long-lasting median multiple sclerosis parameter Patient patients performed peripheral peripheral lymphocyte Plasma cell positive correlation positively correlated preserved profile receiving required Retrospective study SARS-CoV-2 transmission SARS-CoV-2 vaccination SARS-CoV-2 vaccine severe disease T cell response titre titres treatment regimen vaccinate vaccination vaccine dose were assessed were measured
[DOI] 10.1136/jnnp-2021-328197 PMC 바로가기 [Article Type] Article

SARS-CoV-2 vaccination can elicit a CD8 T-cell dominant hepatitis

SARS-CoV-2 예방 접종은 CD8 T 세포 우성 간염을 유발할 수 있습니다

Case Reports

Published on 2022-09-012022-09-12
Journal: Journal of hepatology [Category] A형 간염, COVID19(2023년), Fulltext, MERS, SARS, 진단,

[키워드] accumulate activated activated T cell antibody Autoimmune Autoimmune hepatitis B cells bimodal BNT162b2 mRNA vaccination CD4 T cells CD8 T cell CD8 T-cell CD8+ CD8+ T cell Cell contribute controls correlated COVID-19 COVID-19 vaccination Cytometry described dissect distribution dominant elicit ELISA feature Flow Hepatitis identify imaging immune immune correlates immune profiling Immune-mediated Immunity immunoglobulins Immunosuppression individual Inflammation intrahepatic Laboratory results liver Liver disease male myeloid cell occur pathophysiology Patient Peripheral blood phenotype Plasma cell presenting reactive SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination severity systemic steroids T cell T cells tissue unique vaccination virus-specific T cell was performed
[DOI] 10.1016/j.jhep.2022.03.040 PMC 바로가기 [Article Type] Case Reports

Immune modulation as a consequence of SARS-CoV-2 infection

Article

Published on 2022-08-302022-11-15
Journal: Frontiers in Immunology [Category] SARS, 진단, 치료기술,

Maternal vaccination as an additional approach to improve the protection of the nursling: Anti-infective properties of breast milk

Article

Published on 2022-08-102022-11-15
Journal: Clinics [Category] 진단,

[키워드] anti-SARS-CoV-2 anti-SARS-CoV-2 vaccines antibody Antibody Response approach B lymphocyte bacterial antigen Bioactive factors Breast breast milk Breastfeeding chemokines complement component cytokine elevated Factors fatty acids function Growth factors hormone Human IgA IgA antibodies IgA antibody IgG antibody IMPROVE inactivated induce lactation lactoferrin leukocyte mammary Maternal maternal immunization MicroRNAs nucleic acids oligosaccharides pandemic passive immunity performed Placenta Plasma cell plethora polysaccharide Pregnancy produced Proteins respiratory infections respiratory tracts secretion secretory secretory IgA Secretory IgA antibodies. Specific specific antibody unique vaccination Vaccine Vaccines virus virus-neutralizing viruses
[DOI] 10.1016/j.clinsp.2022.100093 PMC 바로가기

Intranasal administration of a virus like particles-based vaccine induces neutralizing antibodies against SARS-CoV-2 and variants of concern

입자 기반 백신과 같은 바이러스의 비강 투여는 SARS-CoV-2 및 우려되는 변이체에 대한 중화 항체를 유도합니다.

Article

Published on 2022-08-012022-09-11
Journal: Allergy [Category] COVID19(2023년), SARS, 변종, 진단,

[키워드] administration Aerosols antibody antibody response against candidate vaccine Cell clinical trial contagious COVID-19 displaying elicited epitope evaluated help helper cell IgA antibodies IgA antibody immune response immunogenicity induce intranasal ligands local immune response lung tissue maintain Mask Masks mucosal mucosal immune murine model neutralize neutralizing antibody plasma Plasma cell platform Protective RBD RBD of SARS-CoV-2 recognize reduce required respiratory respiratory droplet Respiratory droplets SARS-CoV-2 Seven systemic and local T helper cell TLR7 TLR7/8 Transmission transmitted tropism tropism of SARS-CoV-2 Vaccine vaccine platform Vaccines variants of concern Viral viral shedding virus Virus-like particle virus-like particles VLPs VOCs
[DOI] 10.1111/all.15311 PMC 바로가기 [Article Type] Article

Autoimmune hepatitis with history of HCV treatment triggered by COVID-19 vaccination: case report and literature review

코로나19 예방접종으로 촉발된 HCV 치료 이력이 있는 자가면역 간염: 증례 보고 및 문헌 검토

Review

Published on 2022-08-012022-09-11
Journal: Clinical journal of gastroenterology [Category] 치료제,

COVID-19 and plasma cells: Is there long-lived protection?

COVID-19 및 형질 세포: 오래 지속되는 보호 기능이 있습니까?

Review

Published on 2022-08-012022-09-11
Journal: Immunological reviews [Category] COVID19(2023년), MERS, SARS, 변종, 진단,

Acute Surge of Atypical Memory and Plasma B-Cell Subsets Driven by an Extrafollicular Response in Severe COVID-19

심각한 COVID-19에서 난포 외 반응에 의해 구동되는 비정형 기억 및 혈장 B-세포 하위 집합의 급성 급증

Article

Published on 2022-07-082022-09-12
Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, 진단,

[키워드] accumulating acute phase acute respiratory syndrome addition anti-SARS-CoV-2 antibody Antibody Response Atypical B cell B cells B-cell B-cell response BCR Cell Clinical severity coronavirus coronavirus disease COVID-19 COVID-19 patient Critical cytokine expression dataset disease course Disease progression disease severity driven by driver elevated Evidence extrafollicular response feature Features groups heterogeneous humoral Humoral immunity Inflammatory investigated mechanism memory B cell moderate naïve pandemic pathogenic pathway PC2 Peripheral blood plasma Plasma cell Plasma cells progression public health receptor response RNA robust Sequencing analysis severe COVID-19 severe COVID-19 patients severe disease severe patients severity single-cell subset Trajectory analysis transcriptional Vaccine with COVID-19
[DOI] 10.3389/fcimb.2022.909218 PMC 바로가기 [Article Type] Article

Analysis of memory B cells identifies conserved neutralizing epitopes on the N-terminal domain of variant SARS-Cov-2 spike proteins

기억 B 세포의 분석은 변이체 SARS-Cov-2 스파이크 단백질의 N-말단 도메인에서 보존된 중화 에피토프를 식별합니다

Article

Published on 2022-06-142022-09-11
Journal: Immunity [Category] COVID19(2023년), MERS, SARS, 변종, 진단,

[키워드] anti-NTD neutralizing antibodies. antibodies antibody capture Cell class clinical outcomes Cohort conserved contribute Course domain epitope Epitopes Gamma group identify infected individuals Infection memory B cell memory B cells N-terminal domain neutralized Neutralizing Neutralizing antibodies Neutralizing antibody response neutralizing antibody responses neutralizing epitope NTD omicron plasma Plasma cell probe producing Rapid RBD Re-infection Receptor-binding domain recruitment SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variants Spike protein spike trimer Subsequent infection subsequent infections target targeted epitope vaccination variant
[DOI] 10.1016/j.immuni.2022.04.003 PMC 바로가기 [Article Type] Article