Genetic Polymorphisms of P2RX7 but Not of ADORA2A Are Associated with the Severity of SARS-CoV-2 InfectionArticle Published on 2024-06-022024-09-05 Journal: International Journal of Molecular Sciences [Category] update2024, [키워드] adenosine A2A receptor ATP P2X7 receptor COVID-19 Polymorphisms SARS-CoV-2 [DOI] 10.3390/ijms25116135 PMC 바로가기 [Article Type] Article
Colorectal Cancer Risk Prediction Using the rs4939827 Polymorphism of the SMAD7 Gene in the Romanian PopulationArticle Published on 2024-01-192024-09-05 Journal: Diagnostics [Category] update2024, [키워드] Colorectal cancer Disease-free survival Polymorphisms Single nucleotide polymorphism SMAD7 [DOI] 10.3390/diagnostics14020220 PMC 바로가기 [Article Type] Article
Angiotensin-converting enzyme 2 (ACE2) polymorphisms and susceptibility of severe SARS-CoV-2 in a subset of Pakistani populationarticle Published on 2023-06-122024-09-05 Journal: Virology Journal [Category] update2024, [키워드] ACE2 Polymorphisms rs2285666 SARS-CoV-2 SNPs variants [DOI] 10.1186/s12985-023-02091-2 PMC 바로가기 [Article Type] article
Evaluation and limitations of different approaches among COVID-19 fatal cases using whole-exome sequencing dataResearch Published on 2023-01-102024-09-05 Journal: BMC Genomics [Category] update2024, [키워드] COVID-19 genetic association gnomAD Non-invasive prenatal testing Polymorphisms SARS-CoV-2 whole-exome sequencing [DOI] 10.1186/s12864-022-09084-5 PMC 바로가기 [Article Type] Research
Angiotensin-converting enzyme 1 and voltage-gated potassium channel-interacting protein 4 gene polymorphisms in COVID-19 patients from east of IranArticle Published on 2022-11-012022-11-15 Journal: Clinica chimica acta; international journal of cli [Category] 진단, [키워드] ACE1 acute respiratory syndrome affecting Angiotensin-converting enzyme Angiotensin-converting enzyme 1 Care case-control study caused coronavirus Coronavirus disease 2019 COVID-19 COVID-19 pathogenesis COVID-19 patient COVID-19 susceptibility death disease enzyme Ethnic groups Factor Frequency Genetic Genotype genotyped Health healthy controls I/D polymorphism Infection Iran KCNIP4 material outcome pandemic pathogen PCR polymorphism Polymorphisms populations Potassium Prognostic factor Protein Region Research Respiratory disease severe acute respiratory syndrome coronavirus 2 severity statistically significant supported survival Variation Voltage-gated potassium (Kv) channel-interacting protein 4. [DOI] 10.1016/j.cca.2022.09.006 PMC 바로가기
Association of the Transmembrane Serine Protease-2 (TMPRSS2) Polymorphisms with COVID-19Article Published on 2022-09-072022-11-15 Journal: Viruses [Category] SARS, 치료기술, 치료제, [키워드] ACE2 receptor anti-SARS-CoV-2 antibody cellular protease COVID-19 COVID-19 disease disease dominant exonuclease Genetic genetic susceptibility Genotype Haplotype high risk individual Infection lactic acid dehydrogenase LDH Patient patients with COVID-19 polymorphism Polymorphisms Protective risk risk of COVID-19 RT-PCR test SARS-CoV-2 SARS-COV-2 infection Serine TaqMan assays target cells the SARS-CoV-2 TMPRSS2 transmembrane transmembrane serine protease-2 (TMPRSS2). with COVID-19 [DOI] 10.3390/v14091976 PMC 바로가기
Inflammasome Genetic Variants Are Associated with Protection to Clinical Severity of COVID-19 among Patients from Rio de Janeiro, BrazilArticle Published on 2022-09-052022-11-16 Journal: BioMed Research International [Category] SARS, 변종, 유전자 메커니즘, [키워드] activated allele association Asymptomatic Brazil CARD8 center clinical clinical evolution Clinical management clinical manifestations contributing to COVID-19 COVID-19 severity death disease disease severity Factors Genetic Genetic variant Genotype group Haplotype Host host cells Inflammasome Inpatient investigated knowledge logistic regression models mechanism moderate NLRP3 NLRP3 inflammasome outcomes Patient performed polymorphism Polymorphisms profile protection Real-time PCR recruited Rio de Janeiro risk risk factor SARS-COV-2 infection SARS-CoV-2-infected individual scale severe symptom severity Significant single-nucleotide SNP SNPs Symptom the WHO two group two groups variants virus was determined WHO with mild disease [DOI] 10.1155/2022/9082455 PMC 바로가기
Genome-wide association study of SARS-CoV-2 infection in Chinese population중국 인구의 SARS-CoV-2 감염에 대한 게놈 차원의 연관성 연구Article Published on 2022-09-012022-09-11 Journal: European Journal of Clinical Microbiology & Infect [Category] MERS, SARS, 변종, 진단, [키워드] analyzed ANKRD27 association Asymptomatic carried CD200R1L Chinese close contact conducted coronavirus disease Coronavirus disease 2019 correlation COVID-19 COVID-19 severity ERAP1 Exome Genetic genetic association genetic variability Genetic variant genetic variants Genome sequencing Genome-wide association study global public health GWAS heterogeneous individual LINC00700 loci locus MAN1A2 molecular NEIL3 pathogenesis of COVID-19 Patient PCNX2 PLCL2 POLR2A Polymorphisms positive provided recruited SARS-CoV-2 SARS-COV-2 infection SARS-CoV2 Sequencing severity single-nucleotide Single-nucleotide polymorphisms suggested susceptibility symptomatic patient tested therapeutic options ZMAT3 [DOI] 10.1007/s10096-022-04478-5 PMC 바로가기 [Article Type] Article
The relationship between NTCP gene varieties and the progress of liver disease after HBV infection: an updated systematic review and meta-analysisMeta-Analysis Published on 2022-08-012023-06-11 Journal: The American journal of the medical sciences [Category] B형 간염, [키워드] Hepatitis B virus Hepatocellular carcinoma Liver cirrhosis NTCP Polymorphisms [DOI] 10.1016/j.amjms.2022.03.014 [Article Type] Meta-Analysis
The association of COVID-19 severity and susceptibility and genetic risk factors: A systematic review of the literatureReview article Published on 2022-08-012022-10-05 Journal: Gene [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 진단, [키워드] ACE addition affecting age article association CCR5 cellular protease Clinical outcome Comorbidities correlation COVID-19 COVID-19 severity Deletion evaluate expression finding Genetic Genetic predisposition genetic risk genetic susceptibility genetics help HLA haplotypes host genetics IFNs IFNλ immune system individual Mortality mutations polymorphism Polymorphisms Proteins reduced retrieved risk risk factor SARS-CoV-2 several gene severity severity of COVID-19 smoking susceptibility systematic review TLR TMPRSS2 TNF Treatment upregulation vaccination Variability with COVID-19 [DOI] 10.1016/j.gene.2022.146674 [Article Type] Review article