post-translational modification
[용어속성] Term
Proteolytic inactivation of CXCL12 in the lungs and circulation of COVID-19 patients
Original Article
[키워드] COVID-19
CXCL12
lung transplantation
post-translational modification
protease inhibitors
proteolysis
[DOI] 10.1007/s00018-023-04870-0 PMC 바로가기 [Article Type] Original Article
[DOI] 10.1007/s00018-023-04870-0 PMC 바로가기 [Article Type] Original Article
SARS-CoV-2 Infection Induces HMGB1 Secretion Through Post-Translational Modification and PANoptosis
Original Article
[키워드] HMGB1 protein
PANoptosis
post-translational modification
severe acute respiratory syndrome coronavirus 2
[DOI] 10.4110/in.2023.23.e26 PMC 바로가기 [Article Type] Original Article
[DOI] 10.4110/in.2023.23.e26 PMC 바로가기 [Article Type] Original Article
Open Modification Searching of SARS-CoV-2-Human Protein Interaction Data Reveals Novel Viral Modification Sites
Article
[키워드] open modification searching
Phosphorylation
post-translational modification
protein–protein interactions
S-nitrosylation
SARS-CoV-2
ubiquitination
[DOI] 10.1016/j.mcpro.2022.100425 PMC 바로가기
[DOI] 10.1016/j.mcpro.2022.100425 PMC 바로가기
Friend or foe: RIG- I like receptors and diseases
Article
[키워드] Activation
anti-tumor immunity
antibody
Antiviral
antiviral immune response
Autoimmune diseases
autoinflammatory disease
Autoinflammatory diseases
Bacterial infections
cascade
disease
Diseases
Friend
genes encoding
Guidance
Host
IFNs
immunomodulatory therapy
include
involved
malaria
MDA5
mechanism
mechanisms
microRNA
miRNAs
Mutation
polymorphism
post-translational modification
proinflammatory cytokines
Proteins
recent finding
receptor
Regulatory
RIG-I
RLR
RLRs
RLRs.
RNA virus
SARS-CoV-2
Signaling
single-nucleotide
SNPs
transcriptional
type I interferon
[DOI] 10.1016/j.autrev.2022.103161 PMC 바로가기
[DOI] 10.1016/j.autrev.2022.103161 PMC 바로가기
SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry
Article
[키워드] acute respiratory syndrome
Affect
antiviral response
attenuate
caused
chromatin
Control
coronavirus
coronavirus disease
COVID-19
Critical
Deletion
demonstrated
disrupt
Epigenetic
function
global pandemic
Host
host cell
host cell response
Infection
mechanism
mimicking
molecular basis
motif
ORF8
ORF8 gene
post-translational modification
promote
Protein
provide
recent
Region
Regulation
required
SARS-CoV-2
severity of COVID-19
suppress
the SARS-CoV-2
transcriptional regulation
transcriptional response
viral genome
Viral protein
[DOI] 10.1038/s41586-022-05282-z PMC 바로가기
[DOI] 10.1038/s41586-022-05282-z PMC 바로가기
Contributions of the N-terminal intrinsically disordered region of the severe acute respiratory syndrome coronavirus 2 nucleocapsid protein to RNA-induced phase separation
Article
[키워드] activity
acute respiratory syndrome
addition
affected
change
coronavirus
COVID-19 infections
decrease
droplet
engage
Genome
genomic RNA
host infection
induce
intrinsically
liquid-liquid phase separation
modulating
molecular
Mutation
N-terminal
N-terminus
NMR
nucleocapsid protein
omicron
phosphorylated
post-translational modification
Protein
Replication
RNA
RNA concentration
SARS-CoV-2
Structural properties
the SARS-CoV-2
Transcription
undergo
variant
viral replication
virions
[DOI] 10.1002/pro.4409 PMC 바로가기
[DOI] 10.1002/pro.4409 PMC 바로가기
Sulfide regulation of cardiovascular function in health and disease
Reviews
[키워드] Activation
Arrhythmias
Atherosclerosis
Bioavailability
Biological functions
cardiovascular disease
Cardiovascular function
Cardiovascular health
cardiovascular system
cascades
Clinical finding
clinical study
cystathionine β-synthase
disease
enzyme
Enzymes
Health
heart failure
highlight
hydrogen
implication
Injury
Interaction
involved
metabolites
molecular
Myocardial infarction
nitric oxide
Pathologies
polymorphism
post-translational modification
PROTECT
reduced
Regulation
review
shown
single-nucleotide
[DOI] 10.1038/s41569-022-00741-6 [Article Type] Reviews
[DOI] 10.1038/s41569-022-00741-6 [Article Type] Reviews
Early prediction of COVID-19 patient survival by targeted plasma multi-omics and machine learning
Research article
Published on
Journal: Molecular & Cellular Proteomics : MCP [Category] COVID19(2023년), SARS, 바이오마커, 변종, 진단, 치료기술,
Journal: Molecular & Cellular Proteomics : MCP [Category] COVID19(2023년), SARS, 바이오마커, 변종, 진단, 치료기술,
[키워드] BSAbovine serum albumin COVID-19
Dickinson and Company
3-nitrophenylhydrazine
AAAamino acid analysis
Accuracy
ACDacid citrate dextrose
acetonitrile
acid citrate dextrose
ACNacetonitrile
Alpha 1-antichymotrypsin
Alpha-1-antichymotrypsin
amino acid analysis
analysis of variance
ANOVAanalysis of variance
APCS
APOA2
APOA4
APOH Beta-2-glycoprotein 1
Apolipoprotein A-IIAPOA4
Apolipoprotein A-IVAPOH Beta-2-glycoprotein 1
area under the curve
AUC
AUCarea under the curve
B2MBeta-2-microglobulin
BDBecton
Becton
Beta-2-microglobulin
BHTbutylated hydroxyl toluene
bovine serum albumin COVID-19
BQC19
building
butylated hydroxyl toluene
C-reactive protein
C1RLComplement C1r subcomponent-like protein
C2Complement C2
C3Complement C3
C4AComplement C4
C4b-binding protein alpha chain
C4BPAC4b-binding protein alpha chain
C5Complement C5
C7Complement C7
C9Complement C9
CAMPCathelicidin antimicrobial peptide
capillary zone electrophoresis
Carboxypeptidase B2
Cathelicidin antimicrobial peptide
CFBComplement factor B
CFHComplement factor H
Clinical Proteomic Tumor Analysis Consortium
Coagulation factor XIII A chain
Complement C1r subcomponent-like protein
Complement C2
Complement C3
Complement C4
Complement C5
Complement C7
Complement C9
Complement factor B
Complement factor H
Concentration
concentrations
Control
COVID-19 hospitalization
COVID-19 patient
CPB2Carboxypeptidase B2
CPTACClinical Proteomic Tumor Analysis Consortium
CRPC-reactive protein
CST3Cystatin-C
Cystatin-C
CZEcapillary zone electrophoresis
disease severity
dithiothreitol
DTTdithiothreitol
ECMOextracorporeal membrane oxygenation
extracorporeal membrane oxygenation
F13A1Coagulation factor XIII A chain
FAFormic acid
false discovery rate
FDRfalse discovery rate
FGAFibrinogen alpha chain
FGBFibrinogen beta chain
FGGFibrinogen gamma chain
Fibrinogen alpha chain
Fibrinogen beta chain
Fibrinogen gamma chain
FIVE
Formic acid
Gelsolin
Gene name /Protein nameAPCS
globe
GSNGelsolin
haptoglobin
Healthcare system
Heparin cofactor 2
Hospitalization
hospitalized COVID-19 patients
HPhaptoglobin
IAAiodoacetamide
ICUIntensive Care Unit
IGFALSInsulin-like growth factor-binding protein complex acid labile subunit
Insulin-like growth factor-binding protein complex acid labile subunit
intensive care unit
Inter-alpha-trypsin inhibitor heavy chain H2
Inter-alpha-trypsin inhibitor heavy chain H4
iodoacetamide
ITIH2Inter-alpha-trypsin inhibitor heavy chain H2
ITIH4Inter-alpha-trypsin inhibitor heavy chain H4
K3EDTAtripotassium ethylenediaminetetraacetic acid
L-(tosylamido-2-phenyl) ethyl chloromethyl ketoneTrisHCl
LC-MSliquid chromatography-mass spectrometry
LC/MRM-MSliquid chromatography/multiple reaction monitoring mass spectrometry
Leucine-rich alpha-2-glycoprotein
liquid chromatography-mass spectrometry
liquid chromatography/multiple reaction monitoring mass spectrometry
LLOQLower Limit of Quantitation
Lower Limit of Quantitation
LRG1Leucine-rich alpha-2-glycoprotein
lysoPClysophosphatidylcholine
lysophosphatidylcholine
MALDImatrix assisted laser desorption ionization
mass spectrometry
matrix assisted laser desorption ionization
MeOHmethanol
metabolite
methanol
Mortality
MSmass spectrometry
N-acetylmuramoyl-L-alanine amidase
Neuropilin-2
Non-survivors
NPH3-nitrophenylhydrazine
NRP2Neuropilin-2
patient survival
PBSPhosphatase buffered saline
PCAprincipal component analysis
PCRpolymerase chain reaction
PGLYRP2N-acetylmuramoyl-L-alanine amidase
phenylisothiocyanate
Phosphatase buffered saline
PITCphenylisothiocyanate
plasma
polymerase chain reaction
post-translational modification
predict
Predictive
PRG4Proteoglycan 4
principal component analysis
PROS1Vitamin K-dependent protein S
Protein
Proteoglycan 4
PTMpost-translational modification
QCquality control
Quality control
reversed phase ultrahigh performance liquid chromatography
robust
RP-UHPLCreversed phase ultrahigh performance liquid chromatography
SAA2Serum amyloid A-1 and A-2 proteins
SAA4Serum amyloid A-4 protein
SARS-CoV-2SIS
Scientific and Cultural Organization
Sequential Organ Failure AssessmentSPE
SERPINA1Alpha-1-antichymotrypsin
SERPINA3Alpha 1-antichymotrypsin
SERPIND1Heparin cofactor 2
Serum amyloid A-1 and A-2 proteins
Serum amyloid A-4 protein
Serum amyloid P-componentAPOA2
significant difference
SIS
SOFA
solid-phase extractionSVM
SPE
stable-isotope labeled internal standardSOFA
Stratification
Support Vector MachineTPCK
survival
survivor
SVM
The Universal Protein Resource
TPCK
Transthyretin
Treatment
tripotassium ethylenediaminetetraacetic acid
Tris (hydroxymethyl) aminomethane hydrochlorideUNESCO
TrisHCl
TTRTransthyretin
UNESCO
UniProtThe Universal Protein Resource
unique
United Nations EducationalScientific and Cultural Organization
Vascular cell adhesion protein 1
VCAM1Vascular cell adhesion protein 1
Vitamin K-dependent protein S
[DOI] 10.1016/j.mcpro.2022.100277 [Article Type] Research article
[DOI] 10.1016/j.mcpro.2022.100277 [Article Type] Research article