Biomedical applications of engineered heparin-based materialsReview Article Published on 2023-08-102024-09-05 Journal: Bioactive Materials [Category] update2024, [키워드] Biological biomedical applications heparin nanomaterials physicochemical preparation [DOI] 10.1016/j.bioactmat.2023.08.002 PMC 바로가기 [Article Type] Review Article
Omicron Severe Acute Respiratory Syndrome Coronavirus 2 Neutralization by Immunoglobulin Preparations Manufactured From Plasma Collected in the United States and EuropeArticle Published on 2022-10-172022-11-15 Journal: The Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] acute respiratory syndrome antibody collected coronavirus coronavirus 2 coronavirus disease COVID-19 Donor Europe European Immunoglobulin Infection intravenous Intravenous immunoglobulin less neutralization Neutralizing Neutralizing antibodies new virus omicron pandemic plasma preparation Primary Immunodeficiency Prophylaxis proportion raising respiratory SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 antibody potency the United State union United State vaccination variant virus [DOI] 10.1093/infdis/jiac358 PMC 바로가기
Preparation and pre-clinical evaluation of flagellin-adjuvanted NOM vaccine candidate formulated with Spike protein against SARS-CoV-2 in mouse modelArticle Published on 2022-10-012022-11-15 Journal: Microbial pathogenesis [Category] COVID19(2023년), SARS, 진단, [키워드] 3D structure acute respiratory syndrome Analysis anti-S Antigen Antisera bind Cell Cell-mediated immune responses chimeric China Cluster coronavirus cytokine develop docking effective elicit ELISA ENhance evaluated expressed flagellin groups humoral IFN-γ IgG IL-10 IL-17 IL-22 IL-6 immune response immunoinformatics indicated Infection Interaction mice Ni-NTA NOM protein ORF3a outbreak performed pneumonia case preparation promoted Protein purified raised receptor S protein Salmonella SARS-CoV-2 significantly increased spike spleen TLR5 TNF-α Total vaccination Vaccine vaccine candidate vaccine candidates was selected were assessed Wuhan [DOI] 10.1016/j.micpath.2022.105736 PMC 바로가기
High-Throughput COVID-19 Testing of Naso-Oropharyngeal Swabs Using a Sensitive Extraction-Free Sample Preparation MethodArticle Published on 2022-08-312022-11-15 Journal: Microbiology Spectrum [Category] SARS, 치료기술, [키워드] approach calibrated Cobas costly COVID-19 detection system diagnosis of SARS-CoV-2 diagnostic Direct direct method downstream extraction-free extraction-free method gold standard High-throughput Infection International lack less log medium naso-oropharyngeal swab nasopharyngeal swab specimen nucleic acid extraction offer ORF1ab outcome PCR PCR assay per day PlexPCR pool positive sample preparation proteinase protocol purification quantification RdRP reagent reagents reduction in required Respiratory Coronavirus reverse transcription-PCR RNA Roche Sample SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 RNA sensitive sensitivity tested Testing time-consuming Transport Treatment Viral load Viral RNA WHO [DOI] 10.1128/spectrum.01358-22 PMC 바로가기
High activity of an affinity-matured ACE2 decoy against Omicron SARS-CoV-2 and pre-emergent coronavirusesOmicron SARS-CoV-2 및 사전 출현 코로나바이러스에 대한 친화성 성숙 ACE2 유인물의 높은 활성Article Published on 2022-08-252022-09-11 Journal: PLoS ONE [Category] SARS, 변종, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adeno-associated virus affinity airway angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 antigenic antigenic drift binding can not clade complicate coronavirus coronavirus disease Coronavirus disease 2019 Coronaviruses COVID-19 COVID-19 pandemic decoy develop drug Efficacy Evolution exceptional genetic diversity human ACE2 inhibitor intranasal intrinsic mitigate monoclonal antibody mutant nanomolar affinity Neutralizing omicron pandemic populations preparation Prophylaxis receptor Receptor-binding domain sarbecovirus Sarbecoviruses SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 variant SARS-CoV-2 variants severe acute respiratory syndrome Coronavirus Spike protein the SARS-CoV-2 the spike protein therapeutic Threats Treatment Vaccine variant variants viral evolution viral genome viral spike viral strain viral strains virus widespread zoonotic [DOI] 10.1371/journal.pone.0271359 PMC 바로가기 [Article Type] Article
Preparation of the luciferase-labeled antibody for improving the detection sensitivity of viral antigen바이러스 항원의 검출감도 향상을 위한 루시페라제 표지 항체의 제조Article Published on 2022-07-282022-09-11 Journal: Virology Journal [Category] COVID19(2023년), SARS, 치료기술, [키워드] antibody antigen detection antigens applied Automatic Automatic magnet chemiluminescence immune assay (AMCA) auxiliary chemiluminescence clinical evaluation clinical sensitivity detect detection antibody Detection sensitivity Diagnosis ELISA evaluated expected gold Highly sensitive HRP immune IMPROVE Improving inactivated labeled antibody labeling limit of detection luciferase monoclonal antibody nano luciferase nLuc pathogen PCR-negative PCR-positive peroxidase preparation produced reached reporter respiratory syndrome coronavirus respiratory syndrome coronavirus 2 SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 virus sensitivity significantly specificity Spike protein swab sample swab samples the SARS-CoV-2 Viral antigen viral infections viral spike protein virus virus antigens virus detection virus infection [DOI] 10.1186/s12985-022-01855-6 PMC 바로가기 [Article Type] Article
Coordination of SARS-CoV-2 wastewater and clinical testing of university students demonstrates the importance of sampling duration and collection timeSARS-CoV-2 폐수 및 대학생의 임상 시험의 조정은 샘플링 기간 및 수집 시간의 중요성을 보여줍니다Article Published on 2022-07-152022-09-11 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 치료기술, [키워드] Analysis approach Clinical data clinical testing collected Collection complexes Concentration control sample controls coordination correlated COVID-19 COVID-19 pandemic epidemiological Epidemiology evaluated fecal infected individuals Local Method development methodology not different occur populations positive preparation processing provide sample collection SARS-CoV-2 SARS-CoV-2 detection sensitivity shedding shown significantly higher spring Surveillance test result trajectory university virus detection Virus recovery wastewater Wastewater-based epidemiology [DOI] 10.1016/j.scitotenv.2022.154619 PMC 바로가기 [Article Type] Article
Sustaining the Australian respiratory workforce through the COVID-19 pandemic: a scoping literature reviewCOVID-19 전염병을 통해 호주 호흡기 인력 유지: 범위 지정 문헌 검토Review Published on 2022-07-012022-09-11 Journal: Internal medicine journal [Category] COVID19(2023년), SARS, 변종, [키워드] addressed changes in China COVID-19 COVID-19 pandemic Critical care Europe HCW health systems healthcare healthcare worker Healthcare workers Infection intensive care unit intensive care units literature review mass vaccination Mental mental health North America outbreak pandemic preparation recommendation respiratory risk SARS-CoV2 Support Transmission vaccination variant [DOI] 10.1111/imj.15718 PMC 바로가기 [Article Type] Review
Making waves: Wastewater surveillance of SARS-CoV-2 in an endemic future파도 만들기: 풍토병의 미래에 SARS-CoV-2의 폐수 감시Article Published on 2022-07-012022-09-11 Journal: Water research [Category] COVID19(2023년), SARS, 변종, [키워드] attribute attributes changes in circulating Cost-effective COVID-19 COVID-19 pandemic disease disease incidence Endemic epidemiological Epidemiology General population Genome Genome sequencing IMPROVE include Infection Making mass mass surveillance MONITOR Non-invasive pandemic Population population surveillance preparation public health Quantitative reduce SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 variants Spread Surveillance target targets upstream utility vaccination Vaccine variant Viral load viral loads wastewater wastewater surveillance [DOI] 10.1016/j.watres.2022.118535 PMC 바로가기 [Article Type] Article
Assessment of the Benefits of Targeted Interventions for Pandemic Control in China Based on Machine Learning Method and Web Service for COVID-19 Policy SimulationCOVID-19 정책 시뮬레이션을 위한 기계 학습 방법 및 웹 서비스를 기반으로 한 중국의 전염병 통제를 위한 표적 개입의 이점 평가Article Published on 2022-05-202022-09-11 Journal: Biomedical and environmental sciences : BES [Category] COVID19(2023년), SARS, 변종, [키워드] Accuracy assessment assist benefit China Chinese choice Combination compartment model conducted Control coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 outbreak cumulative dropped Effectiveness example Final Impact Intervention Intervention policy simulation machine learning Measures outbreak outcome parameter parameters performed Policy preparation Prevention and control public health Quantitative analysis reliability service Simulation Taking targeted interventions Transmission transmissions vaccination Viral variants was performed Web Xiamen [DOI] 10.3967/bes2022.057 PMC 바로가기 [Article Type] Article