Rational Design of Peptides Derived from Odorant-Binding Proteins for SARS-CoV-2-Related Volatile Organic Compounds RecognitionArticle Published on 2022-06-182023-07-09 Journal: Molecules [Category] COVID19(2023년), [키워드] computational tools odorant-binding protein peptide rational design SARS-CoV-2 Volatile organic compounds [DOI] 10.3390/molecules27123917 PMC 바로가기
Targeting Viral Surface Proteins through Structure-Based DesignReview Published on 2021-07-082022-10-28 Journal: Viruses [Category] COVID-19, [키워드] Antiviral computational protein design emerging respiratory viruses glycoprotein Glycoproteins host cell Intervention Mutation pathogenic virus Prevent Protective public health rational design respiratory viruses Spread structural vaccinology structure-based design surface targeting therapy Vaccine Vaccines viral infection viral particle virus zoonotic origin [DOI] 10.3390/v13071320 PMC 바로가기 [Article Type] Review
COVID-19: Rational discovery of the therapeutic potential of Melatonin as a SARS-CoV-2 main Protease InhibitorResearch Paper Published on 2020-07-302022-10-29 Journal: International Journal of Medical Sciences [Category] COVID-19, MERS, SARS, [키워드] ACE-2 addition angiotensin-converting enzyme 2 Anti-inflammatory antiviral activity binding site carried Cell clinical trials complexes Compound conserved coronavirus COVID-19 described disease disorder docking docking study early stage Effect Efficacy enzyme evaluated globe hospital hyper-inflammation identify immunomodulatory in silico inhibitor inhibitors Interaction Ligand maintain melatonin Molecular docking study mortality rate MPro oxidative stress pandemic PDB pharmacological Protein Data Bank raised rational design reduce SARS-CoV-2 SARS-CoV-2 main protease Sepsis similarity Spread Stage the cytokine storm the disease therapeutic potential Treatment WHO World Health Organization [DOI] 10.7150/ijms.48053 PMC 바로가기 [Article Type] Research Paper
Characterization and stabilization in process development and product formulation for super large proteinaceous particlesReview Published on 2020-07-192023-08-30 Journal: Engineering in Life Sciences [Category] E형 간염, [키워드] characterization denaturation rational design super large proteinaceous particles [DOI] 10.1002/elsc.202000033 PMC 바로가기 [Article Type] Review