Pre-analytical sample stabilization by different sampling devices for PCR-based COVID-19 diagnosticsPCR 기반 COVID-19 진단을 위한 다양한 샘플링 장치에 의한 사전 분석 샘플 안정화Article Published on 2022-09-252022-09-11 Journal: New biotechnology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] Bacterial cell culture systems copy number copy numbers COVID-19 Critical detectability detectable diagnostic diagnostic testing diagnostics examined except for gold gold standard growth handling healthcare worker infectious Infectivity inhibited outbreak pandemic Patient Pre-analytic Quantitative RT-PCR reduction remained RNA RNA stability room temperature Saliva Saliva collection devices SARS-CoV-2 SARS-CoV-2 pandemic SARS-CoV-2 RNA Sensitivity and specificity specimen specimen collection stability Swab Swab systems. temperature test results tested the SARS-CoV-2 Transport Viral Viral RNA [DOI] 10.1016/j.nbt.2022.04.001 PMC 바로가기 [Article Type] Article
Phytochemical Discrimination, Biological Activity and Molecular Docking of Water-Soluble Inhibitors from Saussurea costus Herb against Main Protease of SARS-CoV-2SARS-CoV-2의 주요 프로테아제에 대한 Saussurea costus Herb의 수용성 억제제의 식물화학적 판별, 생물학적 활성 및 분자 도킹Article Published on 2022-08-012022-09-11 Journal: Molecules [Category] SARS, 변종, [키워드] activity andrographolide ATCC Bacterial binding affinity Bioavailability Biological biological activity carbohydrate carbohydrates carboxylic acid catalytic dyad Cell cell entry Compound coronavirus coronavirus SARS-CoV-2 costus COVID-19 Cys145 D614G variant Delta discrimination docked Escherichia coli event Fatty acid fatty acids FIVE followed by Gamma gas chromatography Gas Chromatography-Mass Spectrometry GC-MS GC-MS profiling Herb His41 HSV-1 virus inhibit inhibitor inhibitory effect investigated M pro main protease mass spectrometry medical system molecular docking molecular docking. phytochemical preference prevalent protease Protein pseudovirus ranged residue room temperature SARS-CoV-2 SARS-CoV-2 entry Saussurea Saussurea costus Siddha spike Spike proteins Staphylococcus aureus Sterol Strains tannin tannins temperature these compounds variant virucidal virus VoC water [DOI] 10.3390/molecules27154908 PMC 바로가기 [Article Type] Article
Intranasal Delivery of Thermostable Subunit Vaccine for Cross-Reactive Mucosal and Systemic Antibody Responses Against SARS-CoV-2SARS-CoV-2에 대한 교차 반응성 점막 및 전신 항체 반응을 위한 열안정성 소단위 백신의 비강내 전달Article Published on 2022-05-032022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] ACE2 addition Against Alpha angiotensin angiotensin converting enzyme angiotensin converting enzyme 2 anti-RBD Anti-RBD antibody antibody Antibody Response Antibody responses Antibody titer Antibody titers approved Beta binding binding domain Breakthrough infection breakthrough infections chitosan circulation COVID-19 COVID-19 vaccines CpG cross-reactive delivery Delta variants domain Efficacy effort enzyme exclusion FIVE genetic material help Hesitancy IgA antibodies IgG1 IgG2a IL-12 Immunity immunization IMPROVE induce inhibited interleukin interleukin-12 intranasal intranasal vaccination intranasally isotype Laboratory mice mucosal mucosal immunity. mutant oligonucleotide polypeptide Prevent PROTECT RBD RBD-specific antibodies RBD-specific antibody receptor Receptor binding domain receptor binding domain (RBD) reduce respiratory respiratory viruses response responses room temperature SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants specific antibodies stability subcutaneous vaccination subunit Subunit vaccine systemic temperature the vaccine thermostable upper respiratory tract vaccination Vaccine Vaccine development Vaccine hesitancy vaccine platform variants virus [DOI] 10.3389/fimmu.2022.858904 PMC 바로가기 [Article Type] Article
Long-Term Preservation of SARS-CoV-2 RNA in Silk for Downstream RT-PCR Tests다운스트림 RT-PCR 테스트를 위한 실크에서 SARS-CoV-2 RNA의 장기 보존Article Published on 2022-03-152022-09-11 Journal: Analytical Chemistry [Category] SARS, 유전자 메커니즘, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition ambient assays can be used Chain Reaction circumvent cold chain component Control coronavirus determined by diagnostic distribution eliminating inactivated limit limits Limits of detection mechanism Nuclease nuclease-free water offer pathogen Pathogens PCR assays polymerase chain polymerase chain reaction positive controls preservation preserved primer probe reaction reference standard reverse transcription reverse transcription polymerase chain reaction RNA room temperature RT-PCR RT-PCR reaction RT-PCR reactions SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 RT-PCR severe acute respiratory syndrome Coronavirus Silk silk fibroin stability storage targets temperature Test the SARS-CoV-2 water without affecting [DOI] 10.1021/acs.analchem.2c00169 PMC 바로가기 [Article Type] Article
E.Co.Tech-electrochemical handheld breathalyzer COVID sensing technologyE.Co.Tech-전기화학 휴대용 음주측정기 코로나 감지 기술Article Published on 2022-03-142022-09-11 Journal: Scientific Reports [Category] 바이오마커, 진단, 치료제, [키워드] 95% confidence interval arising breath can be used Concentration COVID demonstrated detect Diagnosis diffusion electrical evaluated faster health monitoring Interaction limit of detection linearity liquid modulation negative and positive nitric oxide Non-invasive pandemic platform prototype reproducibility respiratory inflammation room room temperature SARS CoV SARS CoV-2 sensitivity sensor significantly specificity subject tested Tetrafluoroborate utility [DOI] 10.1038/s41598-022-08321-x PMC 바로가기 [Article Type] Article
Self-collected gargle specimen as a patient-friendly sample collection method for COVID-19 diagnosis in a population context인구 맥락에서 COVID-19 진단을위한 환자 친화적 샘플 수집 방법으로서 자체 수집 된 양치용 표본Article Published on 2022-03-082022-09-01 Journal: Scientific Reports [Category] MERS, SARS, 진단, 치료기술, [키워드] asked Assay systems cause clinical microbiology COVID-19 COVID-19 diagnosis demonstrated detect diagnosed with COVID-19 discomfort gargle healthcare worker Indonesia Infectious-disease diagnostics Inpatient Inpatients limitation nasopharyngeal Oropharyngeal Outpatient outpatients Patient patients PCR testing qRT-PCR remained RNA extraction kit room temperature RT-PCR kits SARS-CoV-2 SARS-CoV-2 testing Scaling sensitivity specimen specimens Swab swab specimen swabs temperature tracing Viral viral infection Viral RNA [DOI] 10.1038/s41598-022-07690-7 PMC 바로가기 [Article Type] Article
Photothermal inactivation of universal viral particles by localized surface plasmon resonance mediated heating filter membrane국소화 된 표면 플라즈몬 공명 매개 가열 필터 멤브레인에 의한 보편적 바이러스 입자의 광열 불 활성화Article Published on 2022-02-022022-09-01 Journal: Scientific Reports [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] 50% tissue culture infective dose cells Chain Reaction coated components Crystal violet Culture deformation denaturation dose effective gold H1Npdm09 HFM inactivation infectious sample infectious samples infective Infective dose Influenza virus irradiation Mardin membrane membrane protein Membrane proteins Nanoparticles Nanophotonics and plasmonics Natural hazards polymerase chain polymerase chain reaction provide qRT-PCR Quality control Quantitative reduce reduction reduction in reverse transcription room temperature SARS-CoV-2 staining surface plasmon surface plasmon resonance surface temperature TCID temperature tissue tissue culture Viral viral gene viral genes viral infectivity viral particle virus titer was reduced [DOI] 10.1038/s41598-022-05738-2 PMC 바로가기 [Article Type] Article
SPEEDS: A portable serological testing platform for rapid electrochemical detection of SARS-CoV-2 antibodiesSPEEDS: SARS-CoV-2 항체의 신속한 전기화학적 검출을 위한 휴대용 혈청학적 테스트 플랫폼Article Published on 2022-02-012022-09-11 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] antibody collected Concentration COVID-19 COVID-19 pandemic COVID-19 patient serum Diagnosis different time point different time points effective vaccine Effective vaccines electrochemical biosensing evaluated Evidence evidence of Health Health crisis human serum IgG IgG and IgM IgM immune response Immunity screening Immunoglobulin Immunoglobulin G immunoglobulin M Infection Patient platform point-of-care Point-of-care diagnosis population immunity provide provided quantification Rapid required room temperature SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 spike protein SARS-CoV-2 virus serological test Serological test. Serological testing serum antibodies serum antibody serum samples Spike protein spread of COVID-19 symptom onset temperature the SARS-CoV-2 the SARS-CoV-2 virus vaccination Viral viral infection [DOI] 10.1016/j.bios.2021.113762 PMC 바로가기 [Article Type] Article
Presence and stability of SARS-CoV-2 on environmental currency and money cards in Utah reveals a lack of live virus유타의 환경 통화 및 머니 카드에 대한 SARS-COV-2의 존재 및 안정성은 살아있는 바이러스가 부족하다는 것을 보여줍니다Research Article Published on 2022-01-252022-09-10 Journal: PLoS ONE [Category] SARS, 치료기술, [키워드] 24 hours 48 hours Brigham Young Campus coins Community contagious COVID-19 pandemic credit cards favor greater initial investigated lack Live virus microbial pathogen Pathogens plastic Presence reduction in reveal room temperature SARS-CoV-2 SARS-CoV-2 RNA shown Spread stability suggested supported swabbing temperature the United State Transmission United States university Utah Viral Viral detection virus [DOI] 10.1371/journal.pone.0263025 PMC 바로가기 [Article Type] Research Article
Accessible detection of SARS-CoV-2 through molecular nanostructures and automated microfluidics분자 나노구조 및 자동화된 미세유체학을 통한 SARS-CoV-2의 접근 가능한 검출Article Published on 2021-12-152022-09-11 Journal: Biosensors & bioelectronics [Category] SARS, 진단, 치료기술, 치료제, [키워드] activate Activation activities automated Automated microfluidics catalytically clinically evaluated complex Coordinate COVID-19 COVID-19 patients Critical Detection limit diagnose diagnostics Electrochemical sensor ENhance enzymatic activity extracted RNA implementation IMPROVE lysate molecular Molecular nanostructures nucleic acid Nucleic acid detection Nucleic acid detection. Patient patients platform Reactions recognize reducing RNA room temperature SARS-CoV-2 SARS-CoV-2 RNA spread of COVID-19 Structure Swab target temperature [DOI] 10.1016/j.bios.2021.113629 PMC 바로가기 [Article Type] Article