ROS production – Communicable Diseases Research

Toxicity and virucidal activity of a neon-driven micro plasma jet on eukaryotic cells and a coronavirus

Article

Published on 2022-10-012022-11-15
Journal: Free radical biology & medicine [Category] COVID19(2023년), SARS, 치료제,

Angiotensin II induces reactive oxygen species, DNA damage, and T cell apoptosis in severe COVID-19

Research article

Published on 2022-09-012022-10-05
Journal: The Journal of Allergy and Clinical Immunology [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘,

[키워드] ACE2 acute respiratory syndrome Admission age Angiotensin II angiotensin II receptor angiotensin-converting enzyme 2 antioxidant Apoptosis coronavirus coronavirus disease COVID-19 COVID-19 pathogenesis death DNA damage DNA oxidation ELISA flow cytometry form healthy controls high plasma level ICU ICU Patients immunofluorescence induce infected with SARS-CoV-2 Infection intensity intensive care Lymphocyte count Lymphocytes lymphopenia monocyte neighboring cells objective oxidative stress Patient patients patients with COVID-19 PBMC Predictive programmed cell death protease reactive oxygen species reactive oxygen specy receptor released responsible Result ROS ROS production SARS-CoV-2 severe COVID-19 survival T cell T-cell Trigger was measured were measured
[DOI] 10.1016/j.jaci.2022.06.020 [Article Type] Research article

SARS-CoV-2 infection of human-induced pluripotent stem cells-derived lung lineage cells evokes inflammatory and chemosensory responses by targeting mitochondrial pathways

인간 유도 만능 줄기 세포 유래 폐 계통 세포의 SARS-CoV-2 감염은 미토콘드리아 경로를 표적으로 하여 염증 및 화학 감각 반응을 유발합니다

Article

Published on 2022-07-012022-09-12
Journal: Journal of cellular physiology [Category] COVID19(2023년), MERS, SARS, 진단,

[키워드] activated acute respiratory syndrome addition Affect airway alveolar alveolar cells Antiviral Apoptosis caused Cell cells chemosensory chemosensory response complexes Consequences coronavirus COVID-19 COVID-19 disease COVID-19 patients Defense developmental distal dysregulation epithelial HMOX1 IL-13 IL-6 immune responses in viral in vitro Increased induced pluripotent stem cells INF-γ infected cell Inflammatory Inflammatory response Lineage lung lung epithelial Lung epithelial cells Lung injury lung tissue maturation mechanism metabolic processe mitochondrial mitochondrial damage. pathway precursor Proinflammatory cytokine proximal replicated response resulting robust ROS ROS production SARS-CoV-2 SARS-COV-2 infection spatiotemporal therapeutic drug TNF-α transcriptomics Transport upregulated upregulation
[DOI] 10.1002/jcp.30755 PMC 바로가기 [Article Type] Article

High generation of reactive oxygen species from neutrophils in patients with severe COVID-19

Research

Published on 2022-06-212022-10-05
Journal: Scientific Reports [Category] 치료기술, 치료법,

Inactivation of SARS-CoV-2 by a chitosan/α-Ag2WO4 composite generated by femtosecond laser irradiation

Research

Published on 2022-05-172022-10-05
Journal: Scientific Reports [Category] COVID19(2023년), SARS, 치료제,

Ergosterol Peroxide Inhibits Porcine Epidemic Diarrhea Virus Infection in Vero Cells by Suppressing ROS Generation and p53 Activation

Article

Published on 2022-02-152022-10-28
Journal: Viruses [Category] Coronavirus, MERS,

Interaction of SARS-CoV-2 with cardiomyocytes: Insight into the underlying molecular mechanisms of cardiac injury and pharmacotherapy

SARS-CoV-2와 심근세포의 상호작용: 심장 손상 및 약물 요법의 기본 분자 메커니즘에 대한 통찰력

Review

Published on 2022-02-012022-09-11
Journal: Biomedicine & pharmacotherapy = Biomédecine & phar [Category] COVID19(2023년), SARS, 치료제,

[키워드] Abnormalities accessory protein accessory proteins ACE2 adopted advent arteries blood cell calcium cardiac cardiac disease cardiac injuries cardiomyocyte cause CD147 circulating complications Coronary arteries COVID-19 COVID-19 patient dysfunction electrical exhibited Express Extracellular vesicles facilitate heart help homeostasis Infection Injury insight integrin Interaction involved Lungs Manifestations manifested mechanism molecular mechanism pathway Pathways pericyte pericytes pharmacotherapy PROTECT Protein receptor reduced Respiratory illness ROS production SARS-CoV-2 SARS-CoV-2 particle SARS-CoV-2 particles SARS-CoV-2 vaccines severe COVID-19 Side effect Side effects signaling pathway Spectrum subject Support the SARS-CoV-2 TMPRSS2 Treatment Vaccine virus
[DOI] 10.1016/j.biopha.2021.112518 PMC 바로가기 [Article Type] Review

Levistolide A Inhibits PEDV Replication via Inducing ROS Generation

Article

Published on 2022-01-272022-10-28
Journal: Viruses [Category] Coronavirus,

Hyperinflammatory environment drives dysfunctional myeloid cell effector response to bacterial challenge in COVID-19

Research Article

Published on 2022-01-102022-10-29
Journal: PLoS Pathogens [Category] COVID-19,

[키워드] abrogated Anti-inflammatory therapy anti-inflammatory treatment autocrine Bacterial Bacterial infection bacterial superinfection bacterial superinfections caused CD11b CD163 CD66b CD86 Cell cellular characterized classical Clusters complicate Course COVID-19 COVID-19 patient COVID-19 patients Critically ill CRP CXCR1 CXCR2 CXCR4 cytokine cytokine levels cytokine signaling Dexamethasone disease severity driven by dysregulated dysregulation elevated Ex vivo exacerbate exhibited expression function functional HLA-DR host response host-response hypercytokinemia Hyperinflammatory ICU IFN-γ IL-4 IL-6 level Immune cell immune cells immune response IMPROVE increased mortality induce Inflammatory marker inflammatory mediator Inflammatory mediators innate immune function Innate immunity low expression monocyte Monocytes MPO myeloid cell NET neutrophil paracrine paralysis patients phenotype phenotypic plasma provide receiving reduced reduction reduction in reflected response ROS production SARS-CoV-2 SARS-CoV-2 pathogenesis subsequent suppressed surface receptor Symptom synergistic systemic inflammation the disease TNF-α treated utility
[DOI] 10.1371/journal.ppat.1010176 PMC 바로가기 [Article Type] Research Article

Hydroxychloroquine treatment on SARS-CoV-2 receptor ACE2, TMPRSS2 and NRP1 expression in human primary pterygium and conjunctival cells

인간의 일차 익상편 및 결막 세포에서 SARS-CoV-2 수용체 ACE2, TMPRSS2 및 NRP1 발현에 대한 히드록시클로로퀸 치료

Multicenter Study

Published on 2022-01-012022-09-11
Journal: Experimental eye research [Category] SARS, 바이오마커,

[키워드] ACE2 ACE2 protein acute respiratory syndrome acute respiratory syndrome coronavirus angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 applied binding Cell cell viability cells Combination concentration of hydroxychloroquine Conjunctiva conjunctival coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 treatment decrease elevated enzyme epithelial evaluate expression fibroblasts host cell host cell receptor Hydroxychloroquine hydroxychloroquine treatment increase in Infection influences neuropilin Neuropilin-1 NRP1 oxidative stress pandemic pathogen Protein protein expression Pterygium reduced reduction respiratory ROS production SARS-CoV-2 SARS-CoV-2 receptor Serine severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Side effect significantly SOD2 Spike protein tissue TMPRSS2 TMPRSS2 expression TMPRSS2 inhibitor TMPRSS2 protein transmembrane serine protease Treatment Treatment strategies type II transmembrane serine protease viability
[DOI] 10.1016/j.exer.2021.108864 PMC 바로가기 [Article Type] Multicenter Study