pH- and Matrix Metalloproteinase-Responsive Multifunctional Bilayer Microneedles Platform for Treatment of Tinea PedispH 및 매트릭스 메탈로프로테이나제 반응성 다기능 이층 마이크로니들 플랫폼을 이용한 무좀 치료Article Published on 2024-05-132024-08-17 Journal: ACS Biomater Sci Eng [Category] 백선증, [키워드] bilayer microneedles FK13-a1 pH- and MMP-responsive salicylic acid tinea pedis
Chloropyridinyl Esters of Nonsteroidal Anti-Inflammatory Agents and Related Derivatives as Potent SARS-CoV-2 3CL Protease Inhibitors강력한 SARS-CoV-2 3CL 프로테아제 억제제로서의 비스테로이드성 소염제 및 관련 유도체의 클로로피리디닐 에스테르Article Published on 2021-09-242022-09-10 Journal: Molecules [Category] SARS, 치료제, [키워드] 3CL 3CLpro 3CLpro inhibitors active site agent Analysis Antiviral antiviral activity carboxylic acid characterized Compound covalent bond covalent inhibitors COVID-19 derivative EDC enzyme ester evaluated exhibited gel ibuprofen ibuprofen derivative in vitro indomethacin indomethacin derivative inhibitor inhibitory activity mode molecular Nonsteroidal potent protease purified Quantitative RdRP RdRp inhibitor Remdesivir salicylic acid salicylic acid derivative SARS-CoV-2 silica silica gel spectral analysis suggested synthesis VeroE6 cells [DOI] 10.3390/molecules26195782 PMC 바로가기 [Article Type] Article
Comparative Anti-Inflammatory Effects of Salix Cortex Extracts and Acetylsalicylic Acid in SARS-CoV-2 Peptide and LPS-Activated Human In Vitro SystemsSARS-COV-2 펩티드 및 LPS- 활성화 된 인간 시험 관내 시스템에서 살릭 피질 추출물 및 아세틸 살리실산의 비교 항 염증 효과Comparative Study Published on 2021-06-232022-08-31 Journal: International Journal of Molecular Sciences [Category] MERS, SARS, 치료제, [키워드] Salix species Acetylsalicylic acid acetylsalicylic acid (ASA) acid activated Anti-inflammatory anti-inflammatory drug Anti-inflammatory drugs Anti-inflammatory effects anti-inflammatory treatment Cell cells co-culture Comparative compounds cortex COVID-19 patient Culture cytokine Cytokines Effect Efficacy enzyme activity Extract Fever Human human body human PBMC IL-10 IL-1β IL-6 IMPROVE in vitro in vitro data Inflammation Inflammatory ingredient intestinal liver cell LPS-activated mediator metabolism outcome Pain PBMCs peptide peptides PGE PGE2 precursor prostaglandin prostaglandin E2 protein expression retained salicin salicylic acid SARS-CoV-2 SARS-CoV-2 peptide SARS-CoV-2 peptides suppressed suppression System therapy Willow willow bark [DOI] 10.3390/ijms22136766 PMC 바로가기 [Article Type] Comparative Study
Chorismate synthase mediates cerebral malaria pathogenesis by eliciting salicylic acid-dependent autophagy response in parasiteChorismate synthase는 기생충에서 살리실산 의존성자가 포식 반응을 유도하여 뇌 말라리아 발병을 중재합니다Research Article Published on 2020-12-152024-07-27 Journal: Biology open [Category] 말라리아, [키워드] Plasmodium berghei ANKA cerebral malaria Chorismate synthase Plasmodium falciparum salicylic acid [DOI] 10.1242/bio.054544 PMC 바로가기 [Article Type] Research Article
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha‐hydroxy acid) for acnearticle Published on 2020-05-012024-09-04 Journal: The Cochrane database of systematic reviews [Category] 대상포진, [키워드] Acne vulgaris Acne Vulgaris/drug therapy Adapalene Adapalene/adverse effects Adapalene/therapeutic use Adolescent Adult Anti-bacterial agents Anti-Bacterial Agents/therapeutic use Benzoyl Peroxide Benzoyl Peroxide/therapeutic use bias Child Clindamycin Clindamycin/adverse effects Clindamycin/therapeutic use Dermatologic Agents Dermatologic Agents/adverse effects Dermatologic Agents/therapeutic use Dicarboxylic Acids Dicarboxylic Acids/adverse effects Dicarboxylic Acids/therapeutic use erythromycin Erythromycin/adverse effects Erythromycin/therapeutic use female Glycolates Glycolates/therapeutic use humans Keratolytic Agents Keratolytic Agents/therapeutic use male Mandelic Acids Mandelic Acids/therapeutic use niacinamide Niacinamide/adverse effects Niacinamide/therapeutic use Patient Dropouts pyruvic acid Pyruvic Acid/adverse effects Pyruvic Acid/therapeutic use Quality of life salicylic acid Salicylic Acid/therapeutic use sulfur Sulfur/therapeutic use Tretinoin Tretinoin/therapeutic use young adult Zinc Zinc/therapeutic use [DOI] 10.1002/14651858.CD011368.pub2 PMC 바로가기 [Article Type] article