Clinical significance and role of coinfections with respiratory pathogens among individuals with confirmed severe acute respiratory syndrome coronavirus-2 infectionArticle Published on 2022-09-022022-11-15 Journal: Frontiers in Public Health [Category] SARS, 치료기술, [키워드] 229E acute respiratory syndrome Adenovirus AdV age analyzed average C-reactive protein (CRP cause children Clinical data clinical feature clinical picture Clinical significance Coinfection collected Combination complications Coronavirus-2 COVID-19 CRP detect determine Diseases distribution highest HKU1 Hospital stay hospitalized patient individual Infection Influenza influenza A Influenza virus involved lymphocyte métapneumovirus NL63 OC43 other respiratory virus outcome Outpatient parainfluenza virus Patient patients with SARS Prevalence Prevent proportion respiratory pathogen respiratory syncytial virus respiratory virus respiratory viruses rhinovirus RSV SARS CoV-2 SARS-CoV-2 SARS-CoV-2 positive patient Screening seasonal coronavirus specimen tested the disease the mean Treatment Viral load virus was determined was used worsening [DOI] 10.3389/fpubh.2022.959319 PMC 바로가기
Sensitivity of severe acute respiratory syndrome coronavirus type 2 rapid antigen point-of-care tests in vaccinated patients백신 접종 환자에서 중증급성호흡기증후군 코로나바이러스 2형 신속항원 현장진단 검사 민감도Article Published on 2022-08-012022-09-11 Journal: European journal of emergency medicine : official [Category] COVID19(2023년), SARS, 치료기술, [키워드] 95% CI 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus age Antigen Antigen point-of-care test asymptomatic patients calculated confidence interval coronavirus COVID-19 infections detect evaluate evaluated inclusion criteria Patient patients performed POC test POC test result POC tests positive public health Rapid recorded reverse transcription PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 positive patient SARS-CoV-2 positive patients security sensitivities sensitivity significantly symptomatic symptomatic and asymptomatic symptomatic and asymptomatic patients symptomatic patient Symptomatic patients test result tested Viral load [DOI] 10.1097/MEJ.0000000000000928 PMC 바로가기 [Article Type] Article
SARS-COV-2 a trigger of myelin oligodendrocyte glycoprotein-associated disorderSARS-COV-2는 수초 희소돌기아교세포 당단백질 관련 장애의 촉발제Article Published on 2022-08-012022-09-12 Journal: Annals of Clinical and Translational Neurology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] affecting antibodies attack Autoimmune disease cross-reactive immune Diagnosis disorder homology Infection MOG nervous system Neurological disorder over Patient SARS-CoV-2 SARS-CoV-2 positive patient spike-protein Support [DOI] 10.1002/acn3.51609 PMC 바로가기 [Article Type] Article
Development of a Mortality Prediction Model in Hospitalised SARS-CoV-2 Positive Patients Based on Routine Kidney Biomarkers일상적인 신장 바이오마커를 기반으로 입원한 SARS-CoV-2 양성 환자의 사망률 예측 모델 개발Article Published on 2022-06-302022-09-11 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), MERS, SARS, 바이오마커, [키워드] Acute kidney injury acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age AKI an area analysed AUROC Biomarker Blood blood test blood tests characteristic Cohort coronavirus COVID-19 creatinine develop development Ethnicity focus foundation hospital hospitalised Humber in-hospital mortality increased mortality Inpatients kidney Kidney function kidney function test Kidney function tests Kidney injury Logistic regression logistic regression model main outcome measure Model Mortality National Health Service NHS outcome Patient patients without AKI PCR test positive positive RT-PCR prediction Prediction model predictor prevalent random Random forest receiver operating characteristic regions respiratory resulting retrospective cohort study routine RT-PCR test SARS-CoV-2 SARS-CoV-2 infected patients SARS-CoV-2 positive patient SARS-CoV-2 positive patients severe acute respiratory syndrome Coronavirus Sex sodium test dataset Trust United Kingdom urea [DOI] 10.3390/ijms23137260 PMC 바로가기 [Article Type] Article
Genomic surveillance of SARS-CoV-2 in patients presenting neurological manifestations신경학적 징후를 보이는 환자에서 SARS-CoV-2의 게놈 감시Article Published on 2022-06-302022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Ageusia analyzed Anosmia Anosmia/ageusia approach Cell Central nervous system CNS coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient evaluate explain feature First wave genomic Genomic surveillance group Host in vitro in vivo individual infections Mutation Nasopharyngeal swab nasopharyngeal swabs neurological manifestation neurological manifestations Neurological symptom Neurological symptoms occur Patient patients presenting raised SARS-CoV-2 SARS-CoV-2 genomes SARS-CoV-2 positive patient selected severe acute respiratory syndrome Coronavirus severe symptoms shown Spectrum subset Support viral fitness viral genome viral sequence viral sequences virus was related while whole genome sequence [DOI] 10.1371/journal.pone.0270024 PMC 바로가기 [Article Type] Article
Epidemiological characterization of SARS-CoV-2 variants in children over the four COVID-19 waves and correlation with clinical presentation네 가지 COVID-19 파동에 걸친 어린이의 SARS-CoV-2 변이체의 역학 특성 및 임상 발현과의 상관 관계Article Published on 2022-06-172022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 진단, [키워드] B.1.1.7 children circulation clade clades correlation COVID-19 defined demonstrated feature Frequency highest Hospitalization Lineage lineages Local manifestation negative correlation pandemic SARS-COV-2 infection SARS-CoV-2 lineage SARS-CoV-2 pandemic SARS-CoV-2 positive patient SARS-CoV-2 transmission SARS-CoV-2 variant severity sustained Transmission Viral load Virological [DOI] 10.1038/s41598-022-14426-0 PMC 바로가기 [Article Type] Article
Performance of the FREND™ COVID-19 IgG/IgM Duo point-of-care test for SARS-CoV-2 antibody detectionSARS-CoV-2 항체 검출을 위한 FREND™ COVID-19 IgG/IgM Duo 현장 진료 테스트의 성능Article Published on 2022-06-012022-09-11 Journal: Acta clinica Belgica [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome analyzed anti-SARS-CoV-2 assays automated Combination comparable COVID-19 COVID-19 pandemic COVID-19 symptom COVID-19 symptoms Cross reactivity dependent on diagnostic different time point different time points Elecsy IgG IgG/IgM IgM IgM/IgG immune response immunoassay multiple serological assay multiple serological assays onset of symptom PCR-confirmed performance POCT point of care point-of-care point-of-care testing reached respiratory Roche Diagnostics SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 positive patient sensitivity Serological testing serum serum sample serum samples Severe acute respiratory syndrome symptom onset time interval [DOI] 10.1080/17843286.2021.1940776 PMC 바로가기 [Article Type] Article
SARS-CoV-2 infections in mRNA vaccinated individuals are biased for viruses encoding spike E484K and associated with reduced infectious virus loads that correlate with respiratory antiviral IgG levelsmRNA 백신을 접종한 개인의 SARS-CoV-2 감염은 스파이크 E484K를 인코딩하는 바이러스에 대해 편향되어 있으며 호흡기 항바이러스성 IgG 수준과 상관관계가 있는 감소된 감염성 바이러스 부하와 관련이 있습니다.Article Published on 2022-06-012022-09-11 Journal: Journal of Clinical Virology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료제, [키워드] A significant reduction accompanied Alpha Alpha variant Amino acid Analysis Anti-viral Antiviral association B.1.1.7 B.1.526 BNT162b2 Breakthrough infection breakthrough infections caused Cell culture change Cohort collected COVID-19 cycle threshold dose E484K early phase ELISA examined Genome ICU admission IgG IgG level IgG levels immunization increase in Infectious virus investigated Lineage Moderna molecular Mortality mRNA mRNA-1273 PCR Pfizer-BioNTech positive positive sample Positive test predominant Protein reduce reduced required respiratory respiratory sample Respiratory samples Sample SARS-CoV-2 SARS-CoV-2 IgG antibody SARS-COV-2 infection SARS-CoV-2 positive patient sequenced Sequencing specimen specimens spike Spike protein symptomatic infection symptomatic infections upper respiratory tract vaccinated individual vaccinated individuals vaccination Vaccines variant Viral Viral load viral loads viral variant virus were used whole genome [DOI] 10.1016/j.jcv.2022.105151 PMC 바로가기 [Article Type] Article
Factors associated with cycle threshold values (Ct-values) of SARS-CoV2-rRT-PCRSARS-CoV 2-rT-PCR의 주기 역치 값(Ct 값)과 관련된 요인Article Published on 2022-05-012022-09-11 Journal: Molecular biology reports [Category] COVID19(2023년), SARS, 치료기술, [키워드] age association Care caution clinical clinical history COVID-19 COVID-19 severity COVID-19 testing Ct values Ct-values cycle cycle threshold Cycle threshold value Cycle threshold values demographics diagnostic distribution distributions examined Factor Health Health care individual information limitation N gene ORF1ab Patient PCR assays PCR test RdRP RdRp gene RdRp genes reported RT-PCR assay RT-PCR assays RT-PCR test SARS-CoV-2 SARS-CoV-2 positive patient SARS-CoV-2 positive patients SARS-CoV-2 RT-PCR test Sex Symptom Symptomatology the patient the SARS-CoV-2 threshold was collected [DOI] 10.1007/s11033-022-07360-x PMC 바로가기 [Article Type] Article
Baseline Plasma Gas6 Protein Elevation Predicts Adverse Outcomes in Hospitalized COVID-19 PatientsObservational Study Published on 2022-04-292022-10-05 Journal: Disease Markers [Category] COVID19(2023년), SARS, 임상, [키워드] Adverse adverse outcome Analysis baseline Biomarker clinical condition Concentration Course COVID-19 COVID-19 severity death discharge disease dysregulation Elevation ELISA enrolled evaluate Evolution fibrosis GAS6 Hospital admission Hospitalization Hypothesis ICU admission Immune homeostasis involved Italy Laboratory likelihood ratio modulating NEWS2 Odds ratio outcome pandemic parameter Patient plasma Plasma level positive predicted predictor Prognosis prognostic prospective observational study Regulation risk ROC Curve SARS-CoV-2 positive patient sensitivity severe disease specificity Stratification Support TAM thrombosis tyrosine kinase receptor variable were measured worsening [DOI] 10.1155/2022/1568352 PMC 바로가기 [Article Type] Observational Study