Biominerals and Bioinspired Materials in Biosensing: Recent Advancements and ApplicationsReview Published on 2024-04-252024-09-05 Journal: International Journal of Molecular Sciences [Category] update2024, [키워드] biomimetic materials biominerals biosensor electrochemical sensors environmental monitoring magnetic biosensor Optical sensors point-of-care diagnostics selectivity sensitivity [DOI] 10.3390/ijms25094678 PMC 바로가기 [Article Type] Review
Long-Term Safety, Efficacy, and Patient-Centered Outcomes of Filgotinib in the Treatment of Rheumatoid Arthritis: Current PerspectivesReview Published on 2023-10-062024-09-04 Journal: Molecular pharmacology [Category] 대상포진, [키워드] disease-modifying antirheumatic drug DMARD JAKi Janus kinase inhibitors RA selectivity [DOI] 10.2147/PPA.S417677 PMC 바로가기 [Article Type] Review
Weak Point of SARS-CoV-2: Human and Viral Ion Channels under External Physical FieldsArticle Published on 2022-12-022023-07-11 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), [키워드] Brownian motions ionic nanochannels Numerical simulations SARS-CoV-2 selectivity Ultrasound viroporins viruses [DOI] 10.3390/ijms232315185 PMC 바로가기
Synthesis, antimicrobial, molecular docking and molecular dynamics studies of lauroyl thymidine analogs against SARS-CoV-2: POM study and identification of the pharmacophore sitesSARS-CoV-2에 대한 라우로일 티미딘 유사체의 합성, 항균, 분자 도킹 및 분자 역학 연구: POM 연구 및 약전 부위 식별Article Published on 2022-08-012022-09-11 Journal: Bioorganic chemistry [Category] COVID19(2023년), SARS, 치료제, [키워드] 6LU7 aliphatic Analysis antimicrobial Antimicrobial activities Antiviral aromatic group Bacteria binding binding affinity characterisation chemical structures Combination complex Compound condition COVID-19 COVID-19 pandemic cytotoxicity distribution drug-likeness drug-resistant drugs evaluate experiment FIVE fungi HCQ help Hydroxychloroquine in silico in vitro indicated Interaction investigated less metabolism molecular molecular docking molecular dynamics Molecular dynamics simulation MONITOR nucleoside nucleoside analog nucleoside analogs observation Pass PASS and POM pharmacophore sites identification Pathologies performed Perspective pharmacokinetic physicochemical physiological condition precursor protease respiratory pathologies SARS-CoV-2 SARS-CoV-2 main protease selectivity shown stability Structure Support synthesis synthesised thymidine Thymidine analogs. Treatment viral respiratory was performed [DOI] 10.1016/j.bioorg.2022.105850 PMC 바로가기 [Article Type] Article
Effects of non-steroidal anti-inflammatory drugs and other eicosanoid pathway modifiers on antiviral and allergic responses: EAACI task force on eicosanoids consensus report in times of COVID-19비스테로이드성 소염제 및 기타 에이코사노이드 경로 조절제가 항바이러스 및 알레르기 반응에 미치는 영향: COVID-19 시대의 에이코사노이드 합의 보고서에 대한 EAACI 태스크포스Article Published on 2022-08-012022-09-11 Journal: Allergy [Category] COVID19(2023년), SARS, 치료제, [키워드] allergic allergic diseases allergic inflammation allergy analgesic effect antagonist Anti-inflammatory anti-inflammatory drug Antipyretic Antiviral applied Asthma Biologicals biologicals. cannabinoids chronic inflammatory disease Consensus COVID-19 COVID-19 treatment Effect eicosanoid General population Horizon identify Inflammation Inflammatory diseases Interaction knowledge leukotriene leukotriene receptor antagonist leukotriene receptor antagonists LTRA mechanism mechanism of action medication medications NERD non-steroidal anti-inflammatory drug Non-steroidal anti-inflammatory drugs NSAID NSAIDS pandemic of COVID-19 pathway Pathways predict prostaglandin prostaglandin D2 Research Respiratory disease respiratory infections response SARS-CoV-2 selectivity Symptom therapy Treatment unmet need viral infection viral infections [DOI] 10.1111/all.15258 PMC 바로가기 [Article Type] Article
MicroRNA of N-region from SARS-CoV-2: Potential sensing components for biosensor developmentSARS-CoV-2의 N-영역 MicroRNA: 바이오센서 개발을 위한 잠재적 감지 구성 요소Article Published on 2022-08-012022-09-11 Journal: Biotechnology and applied biochemistry [Category] SARS, 치료기술, 치료제, [키워드] acute respiratory syndrome Analysis bioinformatics Biomarker biosensor carried complementary Complementary DNA component coronavirus coronavirus disease coronavirus strains COVID-19 Cross-validation database diagnosis of COVID-19 DNA DNA probe early diagnosis framework GC content GCA gene analysis Genome identity In silco analysis Local microRNA miRbase Multiple sequence alignment N-gene parameter Potential probe regions SARS-CoV-2 selectivity sequence Sequence alignment Sequence analysis Severe acute respiratory syndrome strain virus was used [DOI] 10.1002/bab.2239 PMC 바로가기 [Article Type] Article
Point-of-care COVID-19 testing: colorimetric diagnosis using rapid and ultra-sensitive ramified rolling circle amplification현장 진료 COVID-19 테스트: 신속하고 매우 민감한 분기형 롤링 서클 증폭을 사용한 비색 진단Article Published on 2022-08-012022-09-11 Journal: Analytical and bioanalytical chemistry [Category] COVID19(2023년), SARS, 치료기술, [키워드] amplification color change colorimetric detection Colorimetric sensing Combination COVID-19 Diagnosis diagnosis of SARS-CoV-2 diagnostic displaying DNA amplification evidenced gene amplification Genome isothermal isothermal amplification molecular naked eye nucleotide performed point-of-care polymerase positive Prevent probe Propagation Pyrophosphate Ramified rolling circle amplification (RAM) reaction Reactions released respiratory syncytial virus respiratory viral RHthio-CuSO 4 probe Rolling circle amplification SARS-CoV-2 selectivity sensitivity simple treatment temperature this system Treatment virus [DOI] 10.1007/s00216-022-04156-7 PMC 바로가기 [Article Type] Article
Electrochemical immunosensors using electrodeposited gold nanostructures for detecting the S proteins from SARS-CoV and SARS-CoV-2SARS-CoV 및 SARS-CoV-2에서 S 단백질을 검출하기 위해 전기도금된 금 나노구조를 사용하는 전기화학적 면역센서Article Published on 2022-07-012022-09-11 Journal: Analytical and bioanalytical chemistry [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] amperometry Analysis antibody capture carbon carried Complete Device Diagnosis electrode Features gold Gold nanoparticles group immunosensor Ion limit of detection MAA mercaptoacetic acid monolayer point-of-care proof proof of concept Protein protocol reduction S protein S proteins Saliva SAM SARS-CoV SARS-CoV-2 selectivity sensitivity target protein target proteins the S protein Volume was performed was tested [DOI] 10.1007/s00216-022-03956-1 PMC 바로가기 [Article Type] Article
Peptide Binder with High-Affinity for the SARS-CoV-2 Spike Receptor-Binding DomainSARS-CoV-2 스파이크 수용체 결합 도메인에 대한 고친화성을 갖는 펩티드 결합제Article Published on 2022-06-292022-09-11 Journal: ACS applied materials & interfaces [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affinity peptide albumin antigen detection assembly binder binding binding affinity Biomarker Biomarkers bovine bovine serum albumin Characteristics coronavirus Delta diagnostics dissociation Dissociation constant early diagnosis exhibited fluctuation Gamma gold Gold nanoparticle high affinity Human serum albumin identify independent Interaction interface Lambda mutant omicron Omicron variants peptide phage Rapid rapid detection method RBD Receptor-binding domain recombinants respiratory SARS-CoV-2 SARS-CoV-2 spike protein selectivity sensor sequence serum albumin severe acute respiratory syndrome Coronavirus spike Spike protein the binding affinity the RBD the receptor-binding domain the SARS-CoV-2 variants [DOI] 10.1021/acsami.2c03707 PMC 바로가기 [Article Type] Article
Evaluation of electropolymerized molecularly imprinted polymers (E-MIPs) on disposable electrodes for detection of SARS-CoV-2 in saliva타액에서 SARS-CoV-2 검출을 위한 일회용 전극의 전기중합 분자 각인 폴리머(E-MIP) 평가Article Published on 2022-05-082022-09-11 Journal: Analytica chimica acta [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] absence biosensor capture COVID-19 COVID-19 negative crosslinked demonstrated Electrochemical impedance spectroscopy Electrochemical polymerization evaluated functional isothermal LAMP limit of detection log Molecularly imprinted polymers monoclonal antibody monomer N,N'-methylenebisacrylamide National Health Service nine nucleic acid nucleic acid amplification Other respiratory viruses Patient PCA Polymer positive positive sample Principal component principal component analysis pseudoparticle respiratory respiratory viruses Saliva saliva samples SARS-CoV-2 selective selectivity specificity threshold threshold value transfer Treatment UK National Health Service virus [DOI] 10.1016/j.aca.2022.339777 PMC 바로가기 [Article Type] Article