Diagnostic Significance of Serum Long Noncoding HOX Antisense Intergenic Ribonucleic Acid in Patients with Hepatitis B Virus Related Hepatocellular CarcinomaOriginal Article Published on 2024-05-012024-09-05 Journal: The Turkish journal of gastroenterology : the official journal of Turkish [Category] update2024, [키워드] Alpha-Fetoprotein Hepatocellular carcinoma HOX transcript antisense RNA long noncoding RNAs serum biomarker [DOI] 10.5152/tjg.2024.23314 PMC 바로가기 [Article Type] Original Article
Serial measurements of lymphocytes, D-dimer, LDH, and CRP do not improve the ability to predict COVID-19 adverse outcomesRetrospective Clinical Research Report Published on 2023-05-122024-09-05 Journal: The Journal of international medical research [Category] update2024, [키워드] adverse outcome COVID-19 Mortality prediction retrospective cohort serum biomarker [DOI] 10.1177/03000605231173795 PMC 바로가기 [Article Type] Retrospective Clinical Research Report
Sputnik V vaccine-related complications and its impression on inflammatory biomarkers in healthcare providersObservational Study Published on 2023-05-012024-09-02 Journal: Indian Journal of Medical Microbiology [Category] 대상포진, [키워드] COVID-19 serum biomarker Side effects Sputnik-V vaccine [DOI] 10.1016/j.ijmmb.2022.10.012 PMC 바로가기 [Article Type] Observational Study
Efficacy and safety of nitazoxanide in treating SARS-CoV-2 infection: a systematic review and meta-analysis of blinded, placebo-controlled, randomized clinical trialsArticle Published on 2022-11-012022-11-15 Journal: European Journal of Clinical Pharmacology [Category] SARS, 치료제, [키워드] 95% CI 95% confidence interval addition anti-inflammatory effect antiparasitic antiviral activity blinded clinical benefit continuous variable COVID-19 D-dimer D-dimer level death dichotomous variable Disease progression Effect effect size Efficacy and safety element eligibility enrolled Evidence Frequency ICU admission in vitro individual Inflammation Invasive mechanical ventilation lactate dehydrogenase LDH magnitude Meta-analysis Mild moderate Moderate COVID-19 nitazoxanide no difference Patient patients peer-reviewed performed Placebo placebo-controlled positive positive RT-PCR Primary outcome randomized clinical trial RCT RCTs receiving reducing reduction in reported risk SARS-CoV-2 SARS-COV-2 infection secondary outcome serum biomarker SMD standardized mean difference systematic review tested to define treat treated Viral load WBC were used White blood cell with COVID-19 [DOI] 10.1007/s00228-022-03380-5 PMC 바로가기
Acute exacerbation of idiopathic hypereosinophilic syndrome following asymptomatic coronavirus disease 2019: a case reportArticle Published on 2022-08-312022-11-15 Journal: Journal of Medical Case Reports [Category] 바이오마커, 진단, [키워드] abdominal discomfort antibody Asthma Asymptomatic Autoimmune disease Autoimmune diseases back pain Bone marrow Case report caused coronavirus disease COVID-19 cytoplasmic determine develop Diagnosis eosinophilia Eosinophilic eosinophilic granulomatosis with polyangiitis excluded gastrointestinal tract glucocorticoid ground-glass opacity Hypereosinophilic asthma with systemic manifestations Hypereosinophilic syndrome initiated Japanese lesion loss of appetite Lungs multidisciplinary discussion multiple organ involvement multiplex nervous system normal Occurrence Peripheral Neuropathy presenting proliferation quarantine raised rare disease reported Research serum biomarker skin rash Standard therapy suggested Symptom symptomatic syndrome Tachycardia tested the patient Vasculitis weight loss [DOI] 10.1186/s13256-022-03543-z PMC 바로가기
Combining Deep Phenotyping of Serum Proteomics and Clinical Data via Machine Learning for COVID-19 Biomarker DiscoveryCOVID-19 바이오마커 발견을 위한 기계 학습을 통한 혈청 단백질체학 및 임상 데이터의 심층 표현형 결합Article Published on 2022-08-152022-09-11 Journal: International Journal of Molecular Sciences [Category] 바이오마커, 유전자 메커니즘, [키워드] analyzed Biomarker Biomarkers cardiometabolic CD200R1 Central nervous system clinical Clinical practice contributed COVID-19 COVID-19 disease COVID-19 disease severity COVID-19 patient dataset deep disease disease severity Diseases downregulated enrolled Factors IL6 IMPROVE Inflammation KIT LTBP2 lymphocyte lymphocyte counts machine learning MATN3 MCP1 MOST MRAP natural history neurologic neurologic disease neutrophil nine outcome pathology persistence Phenotyping Protective Protein proximity extension assay sera serological data serum biomarker serum biomarkers severe cases small sample size statistical TRANCE unique variable [DOI] 10.3390/ijms23169161 PMC 바로가기 [Article Type] Article
Longitudinal Serum Proteome Characterization of COVID-19 Patients With Different Severities Revealed Potential Therapeutic Strategies다양한 중증도를 가진 COVID-19 환자의 세로 혈청 프로테옴 특성이 잠재적인 치료 전략을 드러냄Article Published on 2022-07-262022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] Activation alteration Analysis Asymptomatic asymptomatic patient asymptomatic patients caused characterization cholesterol cholesterol metabolism Cluster cluster analysis coagulation cascade collected complement Complement activation control group control groups COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients disease Disease progression dysregulation effective expand global healthcare heterogeneity Hierarchical hierarchical cluster analysis immune response individuals involved longitudinal metabolism Mild moderate Moderate COVID-19 moderate COVID-19 patients molecular Non-COVID-19 not recovered Pathogenesis pathophysiological Patient patients performed PLGLB1 Potential potential therapeutic target potential therapeutic targets progression Protein Proteins proteomic proteomics restored Revealed SARS-CoV-2 serum serum biomarker serum biomarkers Serum level serum sample serum samples severity Strategy symptomatic Treatment understanding [DOI] 10.3389/fimmu.2022.893943 PMC 바로가기 [Article Type] Article
A roadmap for serum biomarkers for hepatitis B virus: current status and future outlook Reviews Published on 2022-07-202022-10-05 Journal: Nature reviews. Gastroenterology & hepatology [Category] B형 간염, Fulltext, 바이오마커, 진단, [키워드] antiviral therapy Biomarker Biomarkers causes Clinical practice clinical utility Coalition complementary Course curative develop Disease progression effort HBV HBV disease hepatitis B Hepatitis B virus host response immunological Infection Interpretation knowledge Liver cancer meeting MONITOR participated progression Replication serum biomarker Therapies therapy Treatment Treatment response Vaccine [DOI] 10.1038/s41575-022-00649-z [Article Type] Reviews
Nanoligomers Targeting Human miRNA for the Treatment of Severe COVID-19 Are Safe and Nontoxic in Mice심각한 COVID-19 치료를 위해 인간 miRNA를 표적으로 하는 나노 올리고머는 마우스에서 안전하고 독성이 없습니다Article Published on 2022-07-112022-09-11 Journal: ACS Biomaterials Science & Engineering [Category] COVID19(2023년), SARS, 치료제, [키워드] accumulation acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration antisense therapy Antiviral strategies Antiviral treatment bind biodistribution biodistribution study body weight Compound coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 disease Effect fatality Histopathology Host Host immune response Human human cell human cells immune immunogenicity Infection Inflammation intranasal intraperitoneal intravenous Intravenous administration kidney kidneys liver Lungs mice microRNA miRNA MOST mouse model organ organs pandemic parameters produced question response Safe Safety SARS-CoV-2 serum biomarker serum biomarkers severe acute respiratory syndrome Coronavirus Severe case severe cases spleen targeting tested Urine with infection [DOI] 10.1021/acsbiomaterials.2c00510 PMC 바로가기 [Article Type] Article
Prognostic serum biomarkers in cancer patients with COVID-19: A systematic reviewResearch article Published on 2022-07-012022-10-05 Journal: Translational Oncology [Category] 바이오마커, 치료제, [키워드] Biomarker Biomarkers Cancer cancer patient Cancer patients changes in circulation coronavirus COVID-19 COVID-19 severity COVID-19 treatments CRP Deterioration determine Disease progression down-regulated eligible evaluated Express ferritin hemoglobin IL-6 Immunotherapy LDH literature review MONITOR neoplasm outcome patients patients with COVID-19 PCT predict Prognosis prognostic Prognostic biomarkers Prognostic marker Result SARS-CoV-2 serum biomarker significantly survived systematic review the SARS-CoV-2 Treatment up-regulated utility was performed were measured were used with COVID-19 [DOI] 10.1016/j.tranon.2022.101443 [Article Type] Research article