A Novel Benchmark Dataset for COVID-19 Detection during Third Wave in Pakistan파키스탄의 제3의 물결 동안 COVID-19 탐지를 위한 새로운 벤치마크 데이터 세트Article Published on 2022-08-122022-09-11 Journal: Computational Intelligence and Neuroscience [Category] SARS, 치료기술, [키워드] approach automated caused Chain Reaction Clinicians contribute country COVID-19 COVID-19 infection COVID-19 patient COVID-19 patients COVID-19 sample Decision tree detection detection rate detection system diagnosing Early detection evaluate experiment feature Features help limitations machine learning Medical Science novel PCR PCR test PCR tests PIMS polymerase chain polymerase chain reaction positive reagents Respiratory Coronavirus SARS-CoV-2 separated severe acute respiratory coronavirus Severe infection time-consuming Wave [DOI] 10.1155/2022/6354579 PMC 바로가기 [Article Type] Article
(+)-Usnic acid and its salts, inhibitors of SARS-CoV-2, identified by using in silico methods and in vitro assay(+)-Usnic acid 및 그 염, SARS-CoV-2 억제제, in silico 방법 및 시험관 내 분석을 사용하여 확인Article Published on 2022-07-302022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, 신약개발, 치료제, [키워드] anti-SARS-CoV-2 Antiviral Beta variant beta variants calculated caused compounds continuum COVID-19 COVID-19 treatment database Efficacy immunofluorescence In silico method in vitro in vivo inhibitors inhibitors of SARS-CoV-2 investigated molecular molecular dynamics monoclonal antibodies Mpro protein pandemic positive control Protein target protein-ligand interaction Remdesivir required RMSD SARS-CoV-2 SARS-CoV-2 protein SARS-CoV-2 variants selectivity index severe acute respiratory coronavirus Severe acute respiratory coronavirus-2 sodium surface area targets Treatment treatment for COVID-19 usnic acid Virtual screening was performed was selected [DOI] 10.1038/s41598-022-17506-3 PMC 바로가기 [Article Type] Article
Fatal COVID-19 outcomes are associated with an antibody response targeting epitopes shared with endemic coronaviruses치명적인 COVID-19 결과는 풍토성 코로나바이러스와 공유되는 에피토프를 표적으로 하는 항체 반응과 관련이 있습니다Article Published on 2022-07-082022-09-11 Journal: JCI Insight [Category] COVID19(2023년), MERS, SARS, 진단, 치료법, [키워드] Adaptive immunity antibody Antibody Response Antibody responses antigenic beta-coronavirus characteristic conservation coronavirus coronavirus disease Coronavirus disease 2019 correlated strongly correlation COVID-19 cross-reactive disease Disease progression domain Endemic epitope Epitopes fatal COVID-19 full-length spike protein highest ICU immune response immune responses immunology Imprinting individual Infection Infectious disease intensive care intensive care unit less magnitude not significantly different nucleocapsid outcome outcomes proportion Protective Region respiratory Respiratory Coronavirus response S2 subunit SARS-CoV-2 SARS-CoV-2 nucleocapsid SARS-CoV-2 spike protein severe acute respiratory coronavirus Spike protein Spike proteins subunits the antibody response the SARS-CoV-2 variable regions [DOI] 10.1172/jci.insight.156372 PMC 바로가기 [Article Type] Article
Tumor marker response to SARS-CoV-2 infection among patients with cancer암 환자의 SARS-CoV-2 감염에 대한 종양 표지자 반응Article Published on 2022-07-012022-09-11 Journal: Cancer Medicine [Category] COVID19(2023년), MERS, SARS, 바이오마커, [키워드] Antigen available data Cancer cancer diagnosis Cancer management cancer patient Cancer patients cancer progression carbohydrate Carcinoembryonic antigen Case series case sery CEA clinical Clinical data Clinical management clinical observations condition conducted coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection demographics Diagnosis Electronic health record Elevation Evidence evidence of Health health record implication induce Infection Inflammatory response Inflammatory responses knowledge Laboratory Laboratory test malignancy marker occurred Patient patients Patients with cancer patients with COVID-19 PCR test positive SARS-CoV-2 PCR positive SARS-CoV-2 PCR test Post-infection Research respiratory Respiratory Coronavirus response resulting SARS-CoV-2 SARS-COV-2 infection severe acute respiratory coronavirus severity of COVID-19 solid tumor Treatment Tumor tumor marker tumor markers Viral viral infection [DOI] 10.1002/cam4.4646 PMC 바로가기 [Article Type] Article
Pyronaridine Protects against SARS-CoV-2 Infection in Mouse파이로나리딘은 마우스의 SARS-CoV-2 감염으로부터 보호합니다Article Published on 2022-06-102022-09-11 Journal: ACS Infectious Diseases [Category] COVID19(2023년), SARS, 진단, 치료제, [키워드] Antiviral antiviral activity antiviral drug antiviral drugs approved assist Cell cells chemokine coronavirus COVID-19 demonstrated Ebola Efficacy evaluated in vitro in vivo infiltration inhibit SARS-CoV-2 inhibited involved K18-hACE lung Lung pathology Lungs M pro mice molecular mechanism mouse pro-inflammatory pro-inflammatory cytokines pyronaridine reducing reduction in Remdesivir Replication respiratory Respiratory Coronavirus SARS-CoV-2 SARS-CoV-2 replication severe acute respiratory coronavirus Spike protein statistically significant reduction structure activity relationship the SARS-CoV-2 therapeutic Transgenic mouse Treatment Viral Viral load [DOI] 10.1021/acsinfecdis.2c00091 PMC 바로가기 [Article Type] Article
Impact of Gestational COVID-19 on Neonatal Outcomes: Is Vertical Infection Possible?신생아 결과에 대한 임신성 COVID-19의 영향: 수직 감염이 가능합니까?Observational Study Published on 2022-06-012022-09-11 Journal: The Pediatric Infectious Disease Journal [Category] COVID19(2023년), SARS, 임상, 치료기술, [키워드] acute infection analyzed Asymptomatic biological sample Blood breast milk Chain Reaction Characteristics Clinical characteristics Cohort conditions Cord blood Coronavirus-2 COVID-19 demographic demographic and clinical characteristics evaluated Follow-up hospital Impact in urine Infant Infants Infection life maternal blood meconium microbiologically Mild symptom mild symptoms MOST mother Nasopharyngeal swab nasopharyngeal swabs Neonatal Neonatal infection neonatal period Newborn no difference no differences Placenta polymerase chain reaction Pregnancy pregnant women remained reverse transcriptase reverse transcriptase-polymerase chain reaction SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 viral load SARS-CoV2 severe acute respiratory coronavirus Severe acute respiratory coronavirus-2 Spanish susceptibility tested Transmission transmission of SARS-CoV-2 Urine vertical vertical transmission Viral load viral loads women [DOI] 10.1097/INF.0000000000003518 PMC 바로가기 [Article Type] Observational Study
Rapid Replacement of SARS-CoV-2 Variants by Delta and Subsequent Arrival of Omicron, Uganda, 2021델타에 의한 SARS-CoV-2 변이체의 신속한 교체 및 2021년 우간다 오미크론 도착Article Published on 2022-05-012022-09-11 Journal: Emerging Infectious Diseases [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 community transmission coronavirus coronavirus disease Coronaviruses COVID-19 deep sequencing Delta genomic Genomic surveillance highlight infection control measure omicron pandemic Prevent Rapid rapid replacement replacement Respiratory Coronavirus respiratory infections SARS-CoV-2 severe acute respiratory coronavirus severe acute respiratory coronavirus 2 severe acute respiratory syndrome Coronavirus Surveillance Uganda variant variants viruses whole-genome whole-genome deep sequencing zoonoses [DOI] 10.3201/eid2805.220121 PMC 바로가기 [Article Type] Article
Cardiovascular disturbances in COVID-19: an updated review of the pathophysiology and clinical evidence of cardiovascular damage induced by SARS-CoV-2COVID-19의 심혈관 장애 : SARS-COV-2에 의해 유도 된 심혈관 손상의 병리 생리학 및 임상 증거에 대한 업데이트 된 검토.Review Published on 2022-03-092022-09-10 Journal: BMC Public Health [Category] 치료기술, [키워드] angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme-2 Asymptomatic binding cardiovascular cardiovascular damage cardiovascular disorder Cardiovascular disorders cardiovascular morbidities cardiovascular morbidity cardiovascular system causative agent cause clinical evidence coronavirus coronavirus disease coronavirus disease-2019 Coronavirus-2 COVID-19 Critical cytokine Cytokine storm disease disease manifestation Evolution expresse Follow-up imaging Infection intensive care intensive care unit Mild Mild disease morbidity morbidity and mortality Most patients myocarditis outcome pathophysiology patients Perturbation phenotype Phenotypes Positron emission tomography receptor respiratory respiratory virus SARS-Co SARS-CoV-2 SARS-COV-2 infection severe acute respiratory coronavirus Severe acute respiratory coronavirus-2 severe disease significantly Symptomatic patients systemic Takotsubo cardiomyopathy the disease Thromboembolism Treatment virus [DOI] 10.1186/s12872-022-02534-8 PMC 바로가기 [Article Type] Review
SARS-CoV-2 enzyme-linked immunosorbent assays as proxies for plaque reduction neutralisation testsSARS-COV-2 효소-연결 면역 흡착제 분석 플라크 환원 중화 시험을위한 프록시로서Clinical Trial Published on 2022-03-012022-09-01 Journal: Scientific Reports [Category] MERS, SARS, 임상, 진단, 치료기술, 치료법, 치료제, [키워드] antibodies can be used cells coronavirus correlated detect determined by Diagnostic markers diagnostic test diagnostic tests ELISA enzyme enzyme-linked immunosorbent assay enzyme-linked immunosorbent assays evaluated generate IgG IgG and IgM IgM immune response immune responses Immunoglobulin immunoglobulins infecting likelihood magnitude MOST NAb NAbs neutralisation test neutralising Neutralising Antibodies neutralising antibody nucleocapsid protein plaque Prevent PRNT Receptor binding domain reduction respiratory Respiratory Coronavirus rising robust SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 spike severe acute respiratory coronavirus severe acute respiratory coronavirus 2 Spread subunit titre viral infection virus [DOI] 10.1038/s41598-022-07263-8 PMC 바로가기 [Article Type] Clinical Trial
Co-circulation of two SARS-CoV-2 variant strains within imported pet hamsters in Hong Kong홍콩에서 수입된 애완용 햄스터 내에서 두 개의 SARS-CoV-2 변종 균주의 공동 순환Coronaviruses Published on 2022-02-272022-09-10 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] adaptive animal animals aviation binding energy can not coronavirus COVID-19 Delta delta variant epidemiologically Europe European hamster hamsters Hong Kong Human human ACE2 interspecies molecular docking Netherland Netherlands outbreak Outbreaks Patient phylogenetically positive Prevent RBD reported respiratory Respiratory Coronavirus risk SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 variant SARS-CoV-2 variants severe acute respiratory coronavirus spike mutation spike receptor-binding domain spike variant spike variants strain Strains subsequent suggested susceptible Testing these viruses Transmission triggered variant virus viruses warehouse while zoonosis [DOI] 10.1080/22221751.2022.2040922 PMC 바로가기 [Article Type] Coronaviruses