Intravenous Injection of Coronavirus Disease 2019 (COVID-19) mRNA Vaccine Can Induce Acute Myopericarditis in Mouse Model코로나바이러스 질환 2019(COVID-19) mRNA 백신의 정맥 주사가 마우스 모델에서 급성 심근염을 유발할 수 있음Article Published on 2022-06-102022-09-12 Journal: Clinical Infectious Diseases: An Official Publicat [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] acute respiratory syndrome antigen expression Apoptosis Ballooning degeneration Blood Can cardiac Cardiac pathology change changes clinical manifestations coronavirus coronavirus disease COVID-19 COVID-19 mRNA vaccine different time point dose Evidence evidenced hepatocyte histological change histopathological IL-6 immunization immunostaining in vivo induce infiltrating immune cell inflammatory cell infiltration injection interferon intracardiac intramuscular intravenous Intravenous injection Messenger RNA mice Model mouse mouse model mRNA mRNA expression mRNA vaccine myocytes Myopericarditis Necrosis other organ provided reduce reported risk SARS-CoV-2 serum Serum level significantly significantly higher skeletal tissue Vaccine vaccine injection Vaccines vascular endothelial cells visceral weight loss Withdrawal [DOI] 10.1093/cid/ciab707 PMC 바로가기 [Article Type] Article
SARS-CoV-2 infection induces inflammatory bone loss in golden Syrian hamstersArticle Published on 2022-05-092022-10-04 Journal: Nature Communications [Category] COVID19(2023년), MERS, SARS, 치료기술, 치료법, [키워드] acute respiratory syndrome amplified benefit cascade cause circulating pro-inflammatory cytokine Complication complications of COVID-19 coronavirus COVID-19 COVID-19 patients COVID19 Cytokine dysregulation Effect evaluated Extrapulmonary hamster hamsters increasingly induce Infection Inflammatory inflammatory disease information less Long-term follow-up metabolism organ system pathogenesis of SARS-CoV-2 Patient pro-inflammatory Prophylactic respiratory tract SARS-CoV-2 SARS-COV-2 infection skeletal therapeutic intervention tissue tissues vertebrae viral infection [DOI] 10.1038/s41467-022-30195-w PMC 바로가기 [Article Type] Article
A Custom-Made Electronic Dynamometer for Evaluation of Peak Ankle Torque after COVID-19Observational Study Published on 2022-03-072022-10-04 Journal: Sensors (Basel, Switzerland) [Category] MERS, SARS, 임상, [키워드] Ankle ankle joint both group COVID-19 decrease demonstrated dynamometer Effect evaluate fatigue Final ICC include initial Multivariate analysis muscle Muscle strength Musculoskeletal no significant difference non-COVID-19 group Observational cohort study Participants peak reproducibility SARS-CoV-2 SARS-COV-2 infection skeletal statistical difference Symptom torque two group Variability was measured was obtained with COVID-19 [DOI] 10.3390/s22052073 PMC 바로가기 [Article Type] Observational Study
Extensive progressive heterotopic ossification post-Covid-19 in a man남성의 코로나19 이후 광범위한 진행성 이소성 골화Case Reports Published on 2022-02-012022-09-11 Journal: Bone [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] ACVR1 affecting association Atypical Brain cause characteristic characterized classic Clinical severity Clinical significance coding region coding regions congenital malformation COVID-19 Deletion deletions disorder duplication duplications elbows exonic regions Extensive fascia fibrodysplasia ossificans progressiva form Genetic great toe Hallux valgus healthy Heterotopic ossification include Infection Local mechanism muscle reported SARS-CoV-2 SARS-COV-2 infection severe SARS severe SARS-CoV-2 skeletal skeletal muscles Soft tissue soft tissues spinal cord suffered surgery swelling systemic inflammation trauma variant [DOI] 10.1016/j.bone.2021.116287 PMC 바로가기 [Article Type] Case Reports
Outcome of COVID19 in Patients With Osteogenesis Imperfecta: A Retrospective Multicenter Study in Saudi ArabiaEndocrinology Published on 2022-01-132022-10-31 Journal: Frontiers in Endocrinology [Category] COVID-19, MERS, [키워드] age bisphosphonate children collagen complications condition contributed Course COVID - 19 COVID-19 COVID-19 in patient COVID-19 severity COVID19 disease evaluate Fracture functional genetic disease Genetic diseases genetic disorder hospital Hospitalization IMPROVE ineligible infected with COVID-19 Infection Jeddah Kyphoscoliosis less male Mild mild illness multicenter study Osteogenesis osteogenesis imperfecta outcome Patient patients Pneumonia prognosis of patient reduce Restrictive lung disease Result resulting retrospective Saudi Arabia skeletal the patient vaccination was performed were recorded with COVID-19 [DOI] 10.3389/fendo.2021.800376 PMC 바로가기 [Article Type] Endocrinology
Osteoclast-mediated bone loss observed in a COVID-19 mouse modelCOVID-19 마우스 모델에서 관찰된 파골세포 매개 뼈 손실Article Published on 2022-01-012022-09-11 Journal: Bone [Category] SARS, 치료기술, [키워드] added affected aging analyzed animal Asymptomatic body weight bone Bone mass consequence controls cortical cortical bone COVID-19 criteria days post infection death Decline decrease develop eight euthanized examined expressing fraction greater group groups hACE2 Health healthy help human ACE2 human disease human SARS-CoV-2 increase in increases in Infection intranasal K18-ACE2 K18-hACE2 K18-hACE2 transgenic mice knowledge mice moderate moderate disease moderate to severe Musculoskeletal Musculoskeletal health musculoskeletal system no difference no differences non-infected Osteoclasts parameter Patient plaque forming units Post-infection posture receiving reduction in remained resulting risk robust SARS-CoV-2 SARS-COV-2 infection severe disease skeletal staining TRAP treated Viral load viral loads Volume volume fraction were infected while [DOI] 10.1016/j.bone.2021.116227 PMC 바로가기 [Article Type] Article
Vitamin D: Dosing, levels, form, and route of administration: Does one approach fit all?Article Published on 2021-12-232022-10-28 Journal: Reviews in Endocrine & Metabolic Disorders [Category] COVID-19, SARS, [키워드] administration affecting appear approach bone clinical conditions condition Conference COVID-19 deficiency Diabetes Mellitus different disease Dosing Extraskeletal effects General population Glucocorticoids greater healthy indicated International International Conference kidney liver management mechanism metabolism obesity Osteoporosis outcomes parathyroid hormone Parenteral Patient populations SARS-COV-2 infection skeletal Specific syndrome therapeutic to define treated Vitamin Vitamin D vitamin D administration vitamin D level Vitamin D supplementation [DOI] 10.1007/s11154-021-09693-7 PMC 바로가기 [Article Type] Article
Research Progress in the Treatment of Complications and Sequelae of COVID-19Medicine Published on 2021-12-022022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] addition cardiovascular system caused Complication consequence COVID-19 COVID-19 vaccine digestive system eight eight major systems Endocrine Guidance neurological system patients with COVID-19 Prognosis Progress reduce reported reproductive Research Respiratory system robust Sequelae Side effect skeletal syndrome the epidemic the SARS-CoV-2 the vaccine therapeutic strategy Treatment trials urinary system vaccination virus widespread [DOI] 10.3389/fmed.2021.757605 PMC 바로가기 [Article Type] Medicine
Neurological complications and infection mechanism of SARS-CoV-2SARS-CoV-2의 신경학적 합병증 및 감염 기전Review Published on 2021-11-232022-09-12 Journal: Signal Transduction and Targeted Therapy [Category] MERS, SARS, 진단, 치료제, [키워드] Brain cause caused Central nervous system CNS Complication Diseases of the nervous system Encephalitis Encephalopathy Evidence experimental model experimental models global pandemic Guillain-barrè syndrome incidence infection mechanism Infectious diseases mechanism Meningitis muscular nervous system Neurological complication Neurological diseases Peripheral nervous system potential mechanism potential mechanisms respiratory diseases SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 neuroinvasion skeletal Symptoms syndrome These data were used [DOI] 10.1038/s41392-021-00818-7 PMC 바로가기 [Article Type] Review
The health effects of vitamin D supplementation: evidence from human studies Reviews Published on 2021-11-232022-10-05 Journal: Nature Reviews Endocrinology [Category] 유전자 메커니즘, [키워드] 25OHD activities Adults baseline benefit Cancer Cardiovascular events causal link children Concentration concentrations Consensus consequence deficiency Effect Endocrine evaluated Evidence Health increased risk indicated individual Infant Mendelian randomization studies Mendelian randomization study multiple sclerosis null effects Observational data Older outcome over participant post-hoc analysis Preclinical Prevent prevented progression randomized clinical trial ricket serum serum 25-hydroxyvitamin D skeletal suggested type 2 diabete Vitamin D Vitamin D supplementation [DOI] 10.1038/s41574-021-00593-z [Article Type] Reviews