Stratifying risk of disease in haematuria patients using machine learning techniques to improve diagnosticsOncology Original Research Published on 2024-05-082024-09-05 Journal: Frontiers in Oncology [Category] update2024, [키워드] Biomarkers Bladder cancer decision support system haematuria machine learning Stratification unbalanced data [DOI] 10.3389/fonc.2024.1401071 PMC 바로가기 [Article Type] Oncology Original Research
Enhanced liver fibrosis (ELF) score predicts hepatic decompensation and mortalityResearch Article Published on 2024-03-112024-09-05 Journal: JHEP Reports [Category] update2024, [키워드] Enhanced Liver Fibrosis testing Liver fibrosis Multi-aetiology non-invasive tests Prognostication Referral pathway Stratification [DOI] 10.1016/j.jhepr.2024.101062 PMC 바로가기 [Article Type] Research Article
Using blood transcriptome analysis for Alzheimer’s disease diagnosis and patient stratificationResearch Article Published on 2024-02-072024-09-05 Journal: Alzheimer's & dementia : the journal of the Alzhei [Category] update2024, [키워드] Alzheimer's disease Blood co‐expression Deconvolution Diagnosis neutrophil Stratification Transcriptome [DOI] 10.1002/alz.13691 PMC 바로가기 [Article Type] Research Article
‘Forest malaria’ in Myanmar? Tracking transmission landscapes in a diversity of environments미얀마의 '숲 말라리아'? 다양한 환경에서 전파 경관 추적Article Published on 2023-09-122024-08-01 Journal: Parasites & Vectors [Category] 말라리아, [키워드] Eco-epidemiological zones Environment Greater Mekong Subregion malaria mapping Stratification [DOI] 10.1186/s13071-023-05915-w PMC 바로가기
Multiplex PCR Detection of Respiratory Tract Infections in SARS-CoV-2-Negative Patients Admitted to the Emergency Department: an International Multicenter Study during the COVID-19 PandemicArticle Published on 2022-10-262022-11-15 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] acute respiratory syndrome Adults age age and sex association Bacterial caused Characteristics children circulating coronavirus coronavirus disease country COVID-19 COVID-19 pandemic detect detection determine diagnostic Emergency emergency department etiological agent Europe Evidence hospital human coronavirus Human rhinovirus Infection Intervention logistic regression model métapneumovirus Middle East multicenter study Multiplex PCR multiplex PCR assay Nasopharyngeal swab pandemic Panel pathogen Patient PCR prevalent respiratory respiratory pathogen respiratory syncytial virus respiratory tract respiratory tract infection respiratory viruses SARS-CoV-2 significantly higher Stratification Symptom symptomatic Symptoms target targets tested tract utility variety viral infection viruses [DOI] 10.1128/spectrum.02368-22 PMC 바로가기
An explainable model of host genetic interactions linked to COVID-19 severityArticle Published on 2022-10-262022-11-16 Journal: Communications Biology [Category] 변종, 유전자 메커니즘, [키워드] age and gender Analysis classifiers Cohort contributing to covariates COVID-19 COVID-19 severity dataset Factor Features Follow-up Genetic GWAS high accuracy highest Host identify immune pathways immune system increased risk Inflammatory Interaction Italian patients MCC molecular mechanism offer outcome Patient phenotypic predict predicted Predictive screened several variant Severe COVID-19 Infection severity Signaling significantly Stratification stratified Support tested therapeutic intervention Thoracic variant viral infection WES with COVID-19 [DOI] 10.1038/s42003-022-04073-6 PMC 바로가기
Characterization of coagulopathy and outcomes in cancer patients with severe COVID -19 illness: Longitudinal changes in hospitalized cancer patientsArticle Published on 2022-10-012022-11-15 Journal: Cancer Medicine [Category] COVID19(2023년), SARS, 바이오마커, [키워드] 1:1 Anderson blood cell count Cancer cancer patient Cancer patients CBC center change changes in characterization clinical clinical observations Coagulopathy Complete correlated COVID COVID-19 COVID-19 illness COVID-19 patient Critical CRP death disease elevated feature fibrinogen FIVE future risk had more help hematological hematological cancer Hospital admission Hospital stay Hospitalization Hospitalized IL-6 inflammatory markers interleukin-6 lack longitudinal Lymphocyte count management measure mechanical ventilation mechanism Mortality neutrophil Non-COVID-19 outcome outcomes Peripheral blood Platelet prognostic Prognostic factor required Retrospective analysis risk Risk assessment Serum ferritin severe COVID-19 illness Stratification survival thrombosis Thrombotic complications unique viral infection with COVID-19 [DOI] 10.1002/cam4.4753 PMC 바로가기
Cystatin C is associated with adverse COVID-19 outcomes in diverse populationsResearch article Published on 2022-10-012022-10-05 Journal: iScience [Category] 바이오마커, 변종, 유전자 메커니즘, 임상, [키워드] 95% CI African analyzed association Cohort cohort of patient courses COVID-19 Critical cystatin C demonstrated European Factor functional Hospitalized hospitalized COVID-19 patient Host host response human metabolism ICU admission independent Logistic regression Mortality outcome Patient patients with COVID-19 performed plasma Population populations Predictive prognostic proteomics Stratification UKB Virology with COVID-19 [DOI] 10.1016/j.isci.2022.105040 [Article Type] Research article
CGRP Plasma Levels Correlate with the Clinical Evolution and Prognosis of Hospitalized Acute COVID-19 PatientsArticle Published on 2022-09-262022-11-15 Journal: Viruses [Category] SARS, 바이오마커, [키워드] baseline Biomarker blood sample calcitonin calcitonin gene-related peptide (CGRP) clinical clinical disease Coagulopathy collected correlated correlation COVID-19 Critical diagnosed disease disease severity eligible etiological agent Evolution heterogenous higher risk highlighting Hospitalization Hospitalized hyperinflammation immune modulation In-hospital investigated involved IP10 Italian Laboratory test Level lung majority moderate pandemic pathophysiology Patient peptide performed plasma predicted prospective cohort study pulmonary intravascular coagulopathy. SARS-CoV-2 SARS-CoV-2 patient severe COVID-19 patients severe respiratory failure Stratification Support Vasoactive [DOI] 10.3390/v14102123 PMC 바로가기
Circulating pyruvate is a potent prognostic marker for critical COVID-19 outcomesArticle Published on 2022-09-142022-11-15 Journal: Frontiers in Immunology [Category] SARS, 바이오마커, [키워드] abundance acute phase acute respiratory syndrome Alter Analysis approach assays body mass index C-reactive protein circulating clinical decision Compromised coronavirus COVID-19 COVID-19 pathogenesis COVID-19 patient creatinine criterion Critical Critically ill cut-off value determine disease disrupt driven by dysregulation energy-related metabolites evaluated Extracellular fluorometric quantification Glucose Health Host Host immune response immune response implicated IMPROVE Increased independent predictor Infection Lactate mechanisms metabolism metabolite metabolomics mitochondrial outcome outcomes Patient Potential biomarker Prognosis Prognostic marker provided pyruvate quantification Quantitative recruited risk SARS-CoV-2 SARS-COV-2 infection semi-targeted metebolomics. serum severe COVID-19 illness severity Signaling Stratification Support validation cohort virus [DOI] 10.3389/fimmu.2022.912579 PMC 바로가기