Spatiotemporal pattern recognition and dynamical analysis of COVID-19 in Shanghai, ChinaArticle Published on 2022-12-072022-11-15 Journal: Journal of theoretical biology [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] Analysis Autocorrelation analysis China COVID-19 COVID-19 disease Daily Daily reproduction number diffusion disease dissemination dynamic Dynamic model early stage Effect hotspot IMPROVE mutant omicron outbreak provided retrospective SARS-CoV-2 transmission Shanghai Spatial statistics. spatiotemporal statistical suffered suppress the epidemic [DOI] 10.1016/j.jtbi.2022.111279 PMC 바로가기
The associations between COVID-19 vaccination and psychological disorders among healthcare workers in ChinaArticle Published on 2022-12-012022-11-16 Journal: Journal of affective disorders [Category] COVID19(2023년), SARS, 치료기술, [키워드] adverse event analyzed Anxiety association caused China collected conducted Coverage COVID-19 COVID-19 vaccination COVID-19 vaccine cross-sectional DASS-21 Depression Factor healthcare healthcare worker incidence Logistic regression mean score nonparametric test participant Prevalence Psychological psychological disorder Psychological state Public Health Agency scored significantly higher significantly lower Sociodemographic characteristics Stress Stress Scale subgroups suffered the mean vaccination vaccination rate Vaccines [DOI] 10.1016/j.jad.2022.08.080 PMC 바로가기
Longitudinal survey of humoral and cellular response to SARS-CoV-2 infection in childrenArticle Published on 2022-11-012022-11-15 Journal: Microbiological research [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] Abbott acute infection age analysed anti-RBD IgG antibody antibody blood sample cellular response children COVID-19 decrease diagnosed humoral Humoral response IgG IgG antibodies IgG antibody IgG response immune response Infection longitudinal longitudinal study molecular nasopharyngeal swabs Oxford paediatric patient participant Patient persistence positive SARS-CoV-2 SARS-CoV-2 IgG SARS-COV-2 infection seroconversion rate seroconverted seropositive significant decrease suffered T-cell Response [DOI] 10.1016/j.micres.2022.127145 PMC 바로가기
Characteristics of hospitalized patients with SARS-CoV-2 infection during successive waves of the COVID-19 pandemic in a reference hospital in SpainArticle Published on 2022-10-172022-11-16 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, [키워드] age assisted ventilation Characteristics collected Comorbidities COVID-19 pandemic death delta variant demographic data died enrolled Examining FIVE hospital Hospitalized hospitalized patient incidence Infection intensive care unit medical records mortality rate outcome Patient receive SARS-COV-2 infection Spain successive wave suffered Symptoms the patient those who survived vaccination [DOI] 10.1038/s41598-022-22145-9 PMC 바로가기
Cross-sectional study for COVID-19-related mortality predictors in a Brazilian state-wide landscape: the role of demographic factors, symptoms and comorbiditiesArticle Published on 2022-10-172022-11-15 Journal: BMJ Open [Category] 진단, [키워드] 95% CI Analysis association cardiac epidemiology Clinical severity Comorbidity COVID-19 COVID-19 pandemic criteria criterion cross-sectional study dataset death demographic characteristics Demographic factors diabete diabetes & diagnosed disease disorder Effects electronic medical record endocrinology Epidemiology evaluate Factor health system healthcare highlight hospitalisation hospitalised ICU implementation increased mortality information Intervention kidney kidney & Kidney disease majority measure mitigate Mortality multicollinearity non-hospitalised non-ICU non-ICU patient occurred Patient patients patients older predictor Prevent public health reverse transcription-PCR secondary outcome selected severity Sex state suffered Symptom Urinary tract urinary tract disorders virus [DOI] 10.1136/bmjopen-2021-056801 PMC 바로가기
Detection of SARS-CoV-2 in a dog with hemorrhagic diarrheaArticle Published on 2022-10-122022-11-15 Journal: BMC veterinary research [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] acute respiratory syndrome Affect African amino acid substitution analyzed Asymptomatic B.1.177 Bacterial Cell Ceuta characteristic circulation coronavirus COVID-19 detection diarrhea disease dog Dog COVID-19 excluded fecal gastrointestinal tract Genome Hemorrhagic Highland human SARS-CoV-2 human-to-animal transmission Ile402Val S protein substitution Infection Interaction intrinsic knowledge mapped microbial Microbiome MOST negative test Next-generation sequencing NGS North one health pandemic Pathogens pathology positive presenting RBD Receptor binding domain reported RT-PCR test S protein SARS-CoV-2 SARS-CoV-2 genome sequence Sequencing Spain Spanish suffered Terrier the S protein the spike protein USA variant viral loads viral variant virus West zoonosis [DOI] 10.1186/s12917-022-03453-8 PMC 바로가기
A novel vaccine based on SARS-CoV-2 CD4+ and CD8+ T cell conserved epitopes from variants Alpha to OmicronArticle Published on 2022-10-062022-11-15 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] 100% conserved Analysis Antigen Beta caused CD4 CD4+ CD8 CD8+ T cell clade clades composed confirmed cases conserved COVID-19 cross-protective deaths Delta epitope Epitopes Epsilon Eta Gamma Genome genomes GISAID greater highly antigenic HLA binding hydrophobic IFN-γ IL-10 IL-12 IL-2 IL-6 immune response immune responses immunoinformatics in silico approaches in vivo Lambda long-lasting majority memory Metadata molecular docking Mortality Mutation non-toxic offer omicron ORF ORF1ab ORF8 proteins peptide performed promoted Protein reduced Reinfection SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 variants secretion severity Strains suffered T cell epitope TGF-β Th1 the Spike the vaccine TLR4 Vaccine variant variants virus virus transmission WHO Wuhan [DOI] 10.1038/s41598-022-21207-2 PMC 바로가기
New-Onset and Relapsed Membranous Nephropathy post SARS-CoV-2 and COVID-19 VaccinationArticle Published on 2022-09-282022-11-15 Journal: Viruses [Category] SARS, 진단, [키워드] aberrant immune response Acute kidney injury acute respiratory syndrome AKI antibody Clinical characteristics collected contribute Conventional coronavirus COVID-19 COVID-19 vaccination Cross immunity disease disease onset elevated exceeded FIVE immune response immunosuppressive drug Immunosuppressive medication induce kidney tissue mechanism Membranous nephropathy occurred outbreak Pathogenesis Patient patients phospholipase Phospholipase A2 positive Prognosis receptor remained reported SARS-CoV-2 SARS-COV-2 infection second dose serum subepithelial suffered Treatment vaccination Vaccine Viral antigen virus particle was measured [DOI] 10.3390/v14102143 PMC 바로가기
Coagulation parameters predict COVID-19-related thrombosis in a neural network with a positive predictive value of 98Article Published on 2022-09-282022-11-15 Journal: Frontiers in Immunology [Category] 진단, [키워드] age C-reactive protein changes in clinical complication coagulation factor Coagulation system Cohort complexes complicate COVID-19 COVID-19 infection COVID-19 patient hospital Hospital admission ICU admission IgM Laboratory multifactorial neural net Neural network parameter pathogenesis of COVID-19 Patient patients Positive predictive value predict prediction serum Sex suffered thrombin Thrombin generation thrombosis thrombotic event variable [DOI] 10.3389/fimmu.2022.977443 PMC 바로가기
Most frequently harboured missense variants of hACE2 across different populations exhibit varying patterns of binding interaction with spike glycoproteins of emerging SARS-CoV-2 of different lineagesArticle Published on 2022-09-012022-11-16 Journal: Computers in biology and medicine [Category] COVID19(2023년), SARS, 변종, [키워드] accumulated African amino acid substitution Analysis AY.1 B.1.617.2 B.1.621 binding binding interaction China Combination complexes COVID-19 Delta docking domain Effect exhibited Factors Genetic hACE2 Host human Angiotensin-converting enzyme Interaction investigated Latin Lineage missense variant Missense variants MM/GBSA molecular docking molecular docking analysis molecular dynamics Molecular dynamics simulation MOST Mutation mutations non-Finnish European omicron Population populations predict prevalent protein stability rate of infection RBD Receptor binding risk SARS-CoV-2 SARS-CoV-2 RBD South Asian spike glycoprotein suffered the SARS-CoV-2 Transmissibility variant variants variants of concern viral variant virus was performed Wuhan [DOI] 10.1016/j.compbiomed.2022.105903 PMC 바로가기