A therapy for suppressing canonical and noncanonical SARS-CoV-2 viral entry and an intrinsic intrapulmonary inflammatory responseBiological Sciences Cell Biology Published on 2024-07-192024-09-05 Journal: Proceedings of the National Academy of Sciences of [Category] update2024, [키워드] COVID-19 Inflammation lung organoids macropinocytosis surfactant [DOI] 10.1073/pnas.2408109121 PMC 바로가기 [Article Type] Biological Sciences Cell Biology
Surfactant for a Patient with Refractory Pyopneumothorax and Acute Respiratory Distress Syndrome Due to Pneumococcal Necrotizing Pneumonia Complicated by a Bronchopleural Fistulaarticle Published on 2022-09-302024-09-01 Journal: Pediatr Allergy Immunol Pulmonol [Category] 폐렴구균 감염증, [키워드] acute respiratory distress syndrome Bronchopleural fistula Necrotizing pneumonia Pneumothorax surfactant [Article Type] article
An area of greatest vulnerability – Recent advances in kidney injuryArticle Published on 2022-08-012022-11-16 Journal: Biomedical journal [Category] SARS, 변종, [키워드] Acute kidney injury an area Atherosclerosis can be used Cell cerebral cerebral palsy children chronic Chronic kidney disease COVID-19 diagnose disorder HIV include invasive journal kidney Kidney injury long non-coding RNA metabolomics Metastasis multiple sclerosis observation Other Patient provided recent SARS-CoV-2 variant shown surfactant Therapeutic approach therapy Tuberculosis [DOI] 10.1016/j.bj.2022.07.006 PMC 바로가기
Reduced DMPC and PMPC in lung surfactant promote SARS-CoV-2 infection in obesity폐 계면활성제의 감소된 DMPC 및 PMPC는 비만에서 SARS-CoV-2 감염을 촉진합니다Article Published on 2022-06-012022-09-11 Journal: Metabolism: clinical and experimental [Category] COVID19(2023년), SARS, 변종, [키워드] ACE2 ACE2 expression ACE2 receptor Analysis BALF bind Bronchoalveolar lavage fluid cell-cell fusion assay characterized cholesterol COVID-19 COVID-19 disease COVID-19 pneumonia D614G mutant SARS-CoV-2 Defense DMPC Effect effector cells elevated expressing fat Feeding HEK293T HEK293T cell HEK293T cells High fat diet Hospitalization increased risk Increasing Infection infections inhibited inhibitory effect Inhibitory effects Lipid lipid composition lipid metabolism lipids lung lung surfactant lung tissue Lungs mechanism metabolism mice myristic acid obese obesity outcomes overexpression Phosphatidylcholine Pneumocytes produced promote Protein reduced respiratory virus reversed risk factor SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pseudovirus infection SARS-CoV-2 viral loads severe COVID-19 disease Severe COVID-19 pneumonia Spike protein surfactant the Spike Triglyceride triglycerides trimyristin Type II pneumocyte type II pneumocytes Vero-E6 cell Vero-E6 cells was performed were used wild type [DOI] 10.1016/j.metabol.2022.155181 PMC 바로가기 [Article Type] Article
Inhaled Placental Mesenchymal Stromal Cell Secretome from Two- and Three-Dimensional Cell Cultures Promotes Survival and Regeneration in Acute Lung Injury Model in Mice2차원 및 3차원 세포 배양에서 흡입된 태반 중간엽 간질 세포 Secretome은 마우스의 급성 폐 손상 모델에서 생존 및 재생을 촉진합니다Article Published on 2022-03-222022-09-11 Journal: International Journal of Molecular Sciences [Category] SARS, 유전자 메커니즘, [키워드] acute lung injury acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration adult stem cells ALI model ARDS Cell cell spheroids cell-free therapy content coronavirus COVID-19 COVID-19 pandemic cultivation damaged death effective Effectiveness exhibited Extracellular Extracellular vesicles FIBRIN fibroblast healthcare histological immunomodulating in some Inflammatory Inflammatory diseases inhalation Inhaled investigated lung Lung inflammation Lung injury lung surfactant lung tissue Lungs management Measures mice Model morbidity and mortality Mortality Patient placental potential therapy problem proteomic regeneration regenerative respiratory distress Respiratory distress syndrome restored SARS-CoV-2 Secretome severe acute respiratory syndrome Coronavirus severe pneumonia stromal cell surfactant survival syndrome Taking therapeutic tissue regeneration [DOI] 10.3390/ijms23073417 PMC 바로가기 [Article Type] Article
Erythro-VLPs: Anchoring SARS-CoV-2 spike proteins in erythrocyte liposomesErythro-VLPS : 적혈구 리포좀에서 SARS-COV-2 스파이크 단백질을 고정시킨다Research Article Published on 2022-03-112022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 변종, [키워드] ACE-2 acute respiratory syndrome acute respiratory syndrome coronavirus 2 Administered anchoring angiotensin angiotensin converting enzyme angiotensin converting enzyme 2 assays average binding BLI Blood blood cell Cell coronavirus coronavirus disease COVID-19 cytoplasmic membrane defined dose-dependent Dynamics ELISA enzyme enzyme-linked immunosorbent assay enzyme-linked immunosorbent assays facilitate fluorescent functional insertion intravenously Liposome membranes molecular dynamics novel open outer membrane pandemic Particles platform Protein protocol red blood cell respiratory S-protein SARS-CoV-2 spike SARS-CoV-2 spike protein scattering Seroconversion severe acute respiratory syndrome Coronavirus surfactant the SARS-CoV-2 therapeutic strategy Therapeutics Trial variants virus viruses was used [DOI] 10.1371/journal.pone.0263671 PMC 바로가기 [Article Type] Research Article
A comparison of precipitation and filtration-based SARS-CoV-2 recovery methods and the influence of temperature, turbidity, and surfactant load in urban wastewater강수 및 여과 기반 SARS-CoV-2 회수 방법과 도시 폐수에서 온도, 탁도 및 계면 활성제 부하의 영향 비교Article Published on 2022-02-202022-09-11 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 치료기술, [키워드] Affect Ammonium ammonium sulphate Characteristics choice Concentration COVID-19 Epidemiology experiment Faecal indicator virus Genome glycol had no highlighting influence of temperature less methodology next generation sequencing no significant effect pandemic Polyethylene glycol proportion qRT-PCR RNA RNA detection SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 pandemic Sequencing significant effect sulphate surfactant Surveillance temperature tested the SARS-CoV-2 turbidity virus was recorded wastewater Wastewater concentration [DOI] 10.1016/j.scitotenv.2021.151916 PMC 바로가기 [Article Type] Article
SP-D and CC-16 Pneumoproteins’ Kinetics and Their Predictive Role During SARS-CoV-2 InfectionMedicine Published on 2022-02-082022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] acute respiratory distress acute respiratory distress syndrome age Analysis ARDS association Biomarker blood sample body mass index cell protein club club cell 16 protein collected confounding variable coronavirus correlated COVID-19 death Defense determine Diabetes Mellitus Dyspnea higher risk Hospital admission Host hypertension incidence increase in independent Inflammation initial involved Kinetics Multivariate analysis Neutrophil-to-lymphocyte ratio outcome oxidative stress Patient patients with COVID-19 performed positively correlated predict Predictive Prognosis Prognostic factor Protein Result Retrospective study role SARS-CoV-2 Serum level subsequent surfactant Surfactant protein D syndrome viral outbreak [DOI] 10.3389/fmed.2021.761299 PMC 바로가기 [Article Type] Medicine
Scrutinizing the Feasibility of Nonionic Surfactants to Form Isotropic Bicelles of Curcumin: a Potential Antiviral Candidate Against COVID-19Research Article Published on 2021-12-292022-10-27 Journal: AAPS PharmSciTech [Category] COVID-19, [키워드] Against antiviral activity antiviral therapy benefit Bicelles candidate clinical study conditions COVID-19 COVID-19 patients docking ENhance Ex vivo exhibited form hydrophobic drug investigated Liposome mechanism Mixed micelles molecular docking Non-ionic surfactants permeation Phosphatidylcholine Potential SARS-CoV-2 significantly surfactant TEM therapeutic was used [DOI] 10.1208/s12249-021-02197-2 PMC 바로가기 [Article Type] Research Article
Scrutinizing the Feasibility of Nonionic Surfactants to Form Isotropic Bicelles of Curcumin: a Potential Antiviral Candidate Against COVID-19Research Article Published on 2021-12-292022-10-27 Journal: AAPS PharmSciTech [Category] Coronavirus, COVID-19, SARS, [키워드] Against antiviral activity antiviral therapy benefit Bicelles candidate clinical study conditions COVID-19 COVID-19 patients docking ENhance Ex vivo exhibited form hydrophobic drug investigated Liposome mechanism Mixed micelles molecular docking Non-ionic surfactants permeation Phosphatidylcholine Potential SARS-CoV-2 significantly surfactant TEM therapeutic was used [DOI] 10.1208/s12249-021-02197-2 PMC 바로가기 [Article Type] Research Article