A Review on the use of Synthetic and Recombinant Antigens for the Immunodiagnosis of Tegumentary Leishmaniasisarticle Published on 2024-03-192024-09-05 Journal: Current Medicinal Chemistry [Category] update2024, [키워드] Diagnosis etiologic agents Recombinant multiepitope protein Recombinant protein synthetic peptide Tegumentary leishmaniasis [DOI] 10.2174/0109298673298705240311114203 PMC 바로가기 [Article Type] article
SARS-CoV-2 inhibitory activity of a short peptide derived from internal fusion peptide of S2 subunit of spike glycoproteinarticle Published on 2023-07-152024-09-05 Journal: Virus research [Category] update2024, [키워드] antiviral activity coronavirus internal fusion peptide region S2 Spike glycoprotein SARS-CoV-2 synthetic peptide [DOI] 10.1016/j.virusres.2023.199170 PMC 바로가기 [Article Type] article
Two MP2CL5 Antigen Vaccines from Naegleria fowleri Stimulate the Immune Response against Meningitis in the BALB/c ModelFungal and Parasitic Infections Published on 2023-06-052024-09-05 Journal: Infection and Immunity [Category] update2024, [키워드] membrane protein MP2CL5 Naegleria fowleri protective immune responses Smp145 synthetic peptide Vaccines [DOI] 10.1128/iai.00181-23 PMC 바로가기 [Article Type] Fungal and Parasitic Infections
Humoral Immune Response Diversity to Different COVID-19 Vaccines: Implications for the “Green Pass” Policy다양한 COVID-19 백신에 대한 체액 면역 반응 다양성: "그린 패스" 정책에 대한 시사점Article Published on 2022-05-112022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] ACE2 binding activities Ad26 Ad26.COV2.S age Analysis anti-RBD anti-RBD antibody titer antibody Antibody Response Antibody titer appear assumption average binding BNT162b2 booster vaccination ChAdOx1 ChAdOx1 nCoV-19 ChAdOx1 nCoV-19 vaccine ChAdOx1 nCoV-19 vaccines concentrations country COV2.S COVID-19 COVID-19 infection COVID-19 pandemic detect Diversity elicit elicited eligibility epitope evaluated Features green Green Pass Policy heterogeneous humoral humoral immune response immune Immunity implication individual maintain mRNA mRNA-1273 Neutralizing Neutralizing activity Neutralizing antibodies neutralizing antibody observé Pass peptides Policy Protein Randomly Rapid test rationale RBD RBD-ACE2 reactivity reactogenicity Receptor-binding domain reduce reopening response Safe SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike selected sera serum serum sample significantly spike Spike protein synthetic peptide the receptor-binding domain titer vaccinated individual vaccination Vaccine virus spread [DOI] 10.3389/fimmu.2022.833085 PMC 바로가기 [Article Type] Article
Peptide-based simple detection of SARS-CoV-2 with electrochemical readout전기화학적 판독으로 SARS-CoV-2의 펩티드 기반 단순 검출Article Published on 2022-05-012022-09-11 Journal: Analytica chimica acta [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome coronavirus antigens approaches caused complex coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 detect followed by gold impedance Impedimetric biosensor infected patient infected patients Infectious disease Interaction limit of detection lysed nanomaterials outbreak pandemic path peptide platform Protein reported reproducibility respiratory SARS-CoV-2 SARS-CoV-2 particles SARS-CoV-2 spike protein Screen sensitivity Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 simplicity Spectroscopy spike Spike protein synthetic synthetic peptide tested the Spike virus [DOI] 10.1016/j.aca.2022.339739 PMC 바로가기 [Article Type] Article
Two Different Therapeutic Approaches for SARS-CoV-2 in hiPSCs-Derived Lung OrganoidshiPSC에서 파생된 폐 오르가노이드에서 SARS-CoV-2에 대한 두 가지 다른 치료 접근 방식Article Published on 2022-04-052022-09-11 Journal: Cells [Category] COVID19(2023년), SARS, 바이오마커, 변종, [키워드] ACE2 airways alveolar approach approaches AT2 candidate Cell complex COVID-19 COVID-19 treatment develop dipeptidyl peptidase Dipeptidyl peptidase-4 distal DPP4 drugs Efficacy Efficiency evaluate Evidence Express expression of gene health emergency hiPSCs hLORGs homologous host cells human cells implicated in vitro in vivo Infection Inflammatory response Innate immunity lung modulation monoclonal Neutralizing neutralizing antibody neutralizing monoclonal antibody organ Organoid peptide pluripotent stem cell Protein proximal pseudovirus receptor receptors reducing reduction SARS-CoV-2 SARS-CoV-2 S SARS-CoV2 SARS-CoV2 pseudovirus spike Spike protein stem cells Structure synthetic peptide tested tetravalent therapeutic These data treated Treatment variant Viral viral entry were infected [DOI] 10.3390/cells11071235 PMC 바로가기 [Article Type] Article
Epitope mapping from Mycobacterium leprae proteins: Convergent data from in silico and in vitro approaches for serodiagnosis of leprosyarticle Published on 2021-10-312024-09-01 Journal: Molecular Immunology [Category] 한센병, [키워드] epitope mapping Immunodiagnosis immunoinformatics in silico prediction leprosy synthetic peptide [Article Type] article
A Peptide-Based Assay Discriminates Individual Antibody Response to the COVID-19 Pfizer/BioNTech mRNA VaccineCommunication Published on 2021-09-032022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] acute respiratory syndrome analyzed antibodies antibody Antibody Response antibody response against appear coronavirus coronavirus disease correlated COVID-19 described different time point dose effective elicited ELISA enzyme-linked immunosorbent first dose individual injection MONITOR mRNA mRNA vaccine Neutralizing antibodies neutralizing capacity pandemic peptide peptide-based peptides persistence Pfizer Pfizer/BioNTech reactive response SARS-CoV-2 selected shown Spike protein subject synthetic peptide the antibody response the SARS-CoV-2 the spike protein vaccination Vaccine was measured [DOI] 10.3390/vaccines9090987 PMC 바로가기 [Article Type] Communication
Resourcing, annotating, and analysing synthetic peptides of SARS-CoV-2 for immunopeptidomics and other immunological studies면역펩티도믹스 및 기타 면역학적 연구를 위한 SARS-CoV-2 합성 펩티드 자원화, 주석 달기 및 분석Article Published on 2021-09-012022-09-11 Journal: Proteomics [Category] SARS, 유전자 메커니즘, [키워드] annotation Antigen applied binding affinities caused COVID19 database dataset document Epitopes examined facilitate generate human leukocyte antigen immune immune response immune responses immunological information LC-MS leukocyte library mass spectrometry modifications MS spectra pandemic peptide peptides predicted proteome proteomic provided SARS-CoV-2 SARS-CoV-2 proteome synthetic peptide synthetic peptides T cell T cell epitope T cell epitopes Tandem mass spectrometry target targets the SARS-CoV-2 vaccination [DOI] 10.1002/pmic.202100036 PMC 바로가기 [Article Type] Article
Role of Peptides in Diagnostics진단에서 펩티드의 역할Review Published on 2021-08-172022-09-12 Journal: International Journal of Molecular Sciences [Category] MERS, SARS, 진단, [키워드] Analysis Antigen applicability biofluids Blood Cancer Chemokine receptor clearance Computed tomography COVID-19 diagnostic diagnostics disease Diseases ELISA enzyme enzyme-linked immunosorbent assay evaluated gastrin Gastrin-releasing peptide imaging diagnostic immunogenicity information integrin interleukin interleukin 2 Lateral flow device low molecular weight membrane Microarray molecular molecular imaging molecular weight non-imaging diagnostic penetration peptide peptide-based peptides pet platform point-of-care positron emission Positron emission tomography probe probes Prostate purity radiolabeled receptor Receptor imaging receptors role single-photon emission computed tomography Somatostatin specificity SPECT stability synthetic peptide synthetic peptides tissue tomography [DOI] 10.3390/ijms22168828 PMC 바로가기 [Article Type] Review