Global reports of takotsubo (stress) cardiomyopathy following COVID-19 vaccination: A systematic review and meta-analysisReview article Published on 2022-12-012022-10-05 Journal: IJC Heart & Vasculature [Category] 바이오마커, [키워드] addition age average BNT162b2 Broken heart syndrome Cardiomyopathy Case report ChAdOx1 nCoV-19 Complication concern conducted COVID-19 COVID-19 vaccinations COVID-19 vaccine COVID-19 vaccines ECG Ejection fraction elevated female first dose Google Scholar Hospital stay individual life-threatening LVEF male Messenger RNA Meta-analysis mRNA mRNA vaccine mRNA-1273 occurred onset of symptom Pain participated Patient patients raised receiving second dose Stress Stress cardiomyopathy Symptom Symptoms systematic literature search systematic review Takotsubo cardiomyopathy TCM the mean the patient troponin test vaccination Vaccines ventricular Web of Science with COVID-19 [DOI] 10.1016/j.ijcha.2022.101108 [Article Type] Review article
Network analysis for elucidating the mechanisms of Shenfu injection in preventing and treating COVID-19 combined with heart failureResearch article Published on 2022-09-012022-10-05 Journal: Computers in biology and medicine [Category] COVID19(2023년), SARS, 바이오마커, 유전자 메커니즘, [키워드] acting acute respiratory syndrome Analysis approach biological process biological processe caused cell differentiation China Chinese components Compound compound screening coronavirus COVID-19 COVID-19 case Critical cytokine signaling Cytoscape Cytoscape software Diagnosis drug-likeness Effectiveness enrichment analysis Evidence heart failure Hemostasis identify IL-17 immune system indicated Infection Inflammatory response injection involved KEGG pathway Kyoto Lung injury mechanism Medicine National Health Commission network network analysis novel coronavirus disease objective overlapped Pathway analysis Pathway enrichment analysis Pathways patients with COVID-19 pharmacological mechanism Pharmacological mechanisms Pharmacology progression protein-protein interaction regulated Respiratory failure Result SARS-CoV-2 Shenfu injection signaling pathway Stage suggested syndrome System target targets TCM Th17 therapeutic therapy Traditional treat treating COVID-19 Treatment was used [DOI] 10.1016/j.compbiomed.2022.105845 [Article Type] Research article
A review on computational approaches that support the researches on traditional Chinese medicines (TCM) against COVID-19COVID-19에 대한 전통적인 중국 의약품 (TCM)에 대한 연구를 지원하는 계산 접근법에 대한 검토Review Published on 2022-09-012022-08-31 Journal: Phytomedicine : international journal of phytother [Category] 신약개발, 치료제, [키워드] antiviral agent Antiviral agents antiviral medication applied approach approaches article articles artificial intelligence AutoDock AutoDock vina category caused Chinese collected complex mechanism complex mechanisms Compound computational approach Computational approaches computational method contagious infection contagious infections COVID-19 database death Direct direct-acting Diseases disrupting Drug discovery effort eligible examined exclusion criteria Google Scholar Gromacs help highlight include Inclusion Knowledge-mining lead MD simulation Medicine molecular docking molecular mechanism Network-based approach other diseases Prevention and control Prophylactic provided required Research ResearchGate resource retrieved Science Science Direct Structure-based approach Support targets TCM TCMSP Traditional Traditional Chinese medicine Traditional Chinese Medicine (TCM). Vaccine Web of Science [DOI] 10.1016/j.phymed.2022.154324 PMC 바로가기 [Article Type] Review
Traditional Chinese medicine treatment for COVID-19: An overview of systematic reviews and meta-analysesCovid-19에 대한 전통 중국 의약 치료 : 체계적인 검토 및 메타 분석의 개요Review Published on 2022-09-012022-08-31 Journal: Journal of integrative medicine [Category] meta-analysis, 임상, 치료법, [키워드] addition Analysis assessment can be used caused China Chinese Chinese traditional Chongqing clinical decision Clinical efficacy clinical outcomes clinical trial clinical trials Cochrane Library Combination control group conversion coronavirus disease Coronavirus disease 2019 COVID-19 data extraction Decision making defined development duration of symptoms Efficacy evaluate evaluated Evidence evidence of examined Factors Hospital stay improve clinical outcomes indicated Infrastructure integrative medicine intervention group lung measurement Medicine meta-analyses Meta-analysis meta-analysis Methodological quality moderate Mortality outcome outcome measure performed proliferation Randomized controlled trial Randomized controlled trials rapidly spreading disease review searched SinoMed Symptom systematic review systematic review. systematic reviews TCM therapy Traditional Chinese medicine Treatment Version VIP was used Web of Science were used [DOI] 10.1016/j.joim.2022.06.006 PMC 바로가기 [Article Type] Review
Reveal the Mechanisms of Yi-Fei-Jian-Pi-Tang on Covid-19 through Network Pharmacology Approach네트워크 약리학 접근법을 통해 Covid-19에 대한 Yi-Fei-Jian-Pi-Tang의 메커니즘 공개Article Published on 2022-07-162022-09-11 Journal: Computational Intelligence and Neuroscience [Category] 유전자 메커니즘, [키워드] activated activator Adhesion Molecule AKT AKT1 Alpha Beta binding C-C motif chemokine ligand C-C motif chemokine ligand 2 cancers CASP8 caspase caspase 8 CCL2 chemokine Chinese contribute Corona Critical CXCL8 Cytoscape database demonstrated effective EGFR enhancer enrichment analysis epidermal epidermal growth factor ERBB2 Formula foundation Gene ontology genomes growth factor Herb HIF1a HMOX1 hypoxia ICAM1 IL10 IL1A IL1B IL2 IL4 IL6 ingredient inhibitor inquiry intercellular intercellular adhesion molecule interferon gamma interleukin interleukin 2 Interleukin 4 interleukin 6 JUN KEGG Kyoto Ligand MAPK3 MAPK8 mechanism Medicine mitogen-activated protein kinase MMP1 MMP3 motif MPO myeloperoxidase Necrosis network network pharmacology NFE2 NFE2L2 NFkB NFKBIA nitric oxide nitric oxide synthase NOS3 nuclear oncogene outcome p53 pathway Pathways Patient Pharmacology PPARA Protein protein kinase protein p53 protein-protein interaction receptor RELA Research Serine Stat1 STRING database subunit target target protein targets TCM TGFB1 therapeutic target threonine Timp1 TNF TP53 Traditional Traditional Chinese medicine Transcription transcription factor transforming growth factor Tumor tumor necrosis tumor necrosis factor tyrosine UniProt Virus Disease [DOI] 10.1155/2022/1493137 PMC 바로가기 [Article Type] Article
Decoding herbal materials of TCM preparations with the multi-barcode sequencing approach Research Published on 2022-04-092022-10-05 Journal: Scientific Reports [Category] 바이오마커, 유전자 메커니즘, [키워드] Analysis analyzed approach approach Biomarkers Chinese classical Combination DNA High-throughput sequencing technology ingredient Medicine Previous studies Quality control reliability selected sensitivity sequencing approach shown TCM Traditional trnL [DOI] 10.1038/s41598-022-09979-z [Article Type] Research
Timely treatment and higher compliance to traditional Chinese medicine: New influencing factors for reducing severe COVID-19 based on retrospective cohorts in 2020 and 2021Research article Published on 2022-04-012022-10-05 Journal: Pharmacological research [Category] COVID19(2023년), SARS, 변종, 치료법, [키워드] addition adhere age Antibiotics antiviral medicine association calculated changed characterized Chinese cohort study cohorts collected Compliance Concomitant medication conditions conducted control limit COVID-19 patient COVID-19 patients diagnosed Diagnosis disease E-value effective Effectiveness enrolled Epidemic Factor Final hospital Hospitalization Hospitalized incidence independent risk factor initial symptom initial symptoms LCL less measure Mild mild COVID-19 Moderate COVID-19 multivariate logistic regression New objective outcome participant Patient predict Prognosis progressed proportion public health reduced reducing Result retrospective cohort retrospective cohort study sensitivity analysis Severe case severe cases severe COVID-19 Severity of disease Sex TCM The proportion to severe status Traditional Chinese medicine treat Treatment were used Wuhan [DOI] 10.1016/j.phrs.2022.106174 [Article Type] Research article
Manifestations and Mechanism of SARS-CoV2 Mediated Cardiac InjurySARS-CoV2 매개 심장 손상의 징후 및 메커니즘Review Published on 2022-03-282022-09-11 Journal: International Journal of Biological Sciences [Category] SARS, 치료기술, [키워드] accompanied ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 angiotensin Angiotensin-converting enzyme arrhythmia Autopsy blood vessel blood vessels cardiac cardiac damage cardiac injury caused clinical manifestation clinical manifestations coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Critically ill critically ill patients damaged edema evidenced global pandemic heart heart failure Heart injury heart tissue immune response Injury kidney liver lymphocyte Macrophage Macrophage infiltration manifestation mechanism Mediated membrane Mild morbidity and mortality Mortality Myocardial myocardial injury myocarditis Necrosis organs Patient Respiratory system SARS-CoV2 SARS-CoV2. severe acute respiratory syndrome Coronavirus severe patients significantly Spike protein systemic inflammatory Takotsubo cardiomyopathy TCM the disease tissues Treatment virus virus RNA [DOI] 10.7150/ijbs.69677 PMC 바로가기 [Article Type] Review
Integrated hepatic single-cell RNA sequencing and untargeted metabolomics reveals the immune and metabolic modulation of Qing-Fei-Pai-Du decoction in mice with coronavirus-induced pneumonia통합 된 간 단일 세포 RNA 시퀀싱 및 표적화되지 않은 대사체는 코로나 바이러스-유도 폐렴과 마우스에서 Qing-Fei-Pai-Du 달인의 면역 및 대사 조절을 보여준다.Article Published on 2022-03-012022-08-31 Journal: Phytomedicine : international journal of phytother [Category] 유전자 메커니즘, 치료제, [키워드] alteration Analysis attenuate B cells BALB/c mice best CD4 CD8 clinically Cold Cold-damp environment Combination Control control group coronavirus coronavirus disease Coronavirus disease 2019 Coronavirus pneumonia COVID-19 patients Cytokines damp environment disease disease-associated exposure to Gene Expression HCoV HCoV-229E Human coronavirus IFN-γ IL-6 immune immune function Immunity immunological IMPROVE indicated infecting Infection Inflammation Inflammatory cytokine Inflammatory cytokines knowledge Liver injury liver tissue Lymphocytes mechanism mechanism of action metabolic function metabolism metabolomics mice Model modulate modulation mouse model Mouse models performed Peripheral blood peripheral blood lymphocyte peripheral blood lymphocytes Pneumonia profile purine Qing-Fei-Pai-Du decoction reduce regulated Regulatory reveal RNA RNA sequencing significantly significantly increased Single-cell RNA sequencing status T cells TCM therapy TNF-α transcriptional treat treated Treatment Untargeted metabolomics. [DOI] 10.1016/j.phymed.2021.153922 PMC 바로가기 [Article Type] Article
Screening of potential spike glycoprotein / ACE2 dual antagonists against COVID-19 in silico molecular docking인실리코 분자 도킹에서 COVID-19에 대한 잠재적 스파이크 당단백질/ACE2 이중 길항제의 스크리닝Article Published on 2022-03-012022-09-11 Journal: Journal of virological methods [Category] SARS, 치료제, [키워드] ACE2 antagonist Antiviral antiviral drugs Candidates caused Chinese Chrysophanol component coronavirus disease COVID-19 Dual antagonists effective effective drug effective drugs glycoprotein in silico inhibitory activity Invasion investigated medical resource Medicine molecular docking Novel coronavirus novel coronavirus disease oleanolic acid Recognition rhein SARS-CoV-2 Screening spike spike glycoprotein spike glycoprotein. Spike protein Spread sustained TCM the epidemic Traditional Traditional Chinese medicine Treatment treatment of COVID-19 [DOI] 10.1016/j.jviromet.2021.114424 PMC 바로가기 [Article Type] Article