Are Dyskeratosis Congenita patients at higher risk of symptomatic COVID-19?Correspondence Published on 2022-06-012022-10-05 Journal: Medical Hypotheses [Category] 유전자 메커니즘, [키워드] association BMFBone Marrow Failure bone marrow failure clinical care complex Coronavirus disease 2019 COVID-19 COVID-19coronavirus disease 2019 DCDyskeratosis Congenita disease disorder Dyskeratosis Congenita heterogeneous higher risk increase indicated leukocyte mortality rate mutated Patient RNA severe symptom stem cells symptomatic telomerase Telomere Length TLTelomere Length transcriptase [DOI] 10.1016/j.mehy.2022.110843 [Article Type] Correspondence
Prognostic significance of serum telomerase activity in the monitoring of hepatitis B viral infectionArticle Published on 2022-05-042023-06-12 Journal: Journal of immunoassay & immunochemistry [Category] B형 간염, [키워드] Hepatitis B virus Hepatocellular carcinoma telomerase telomere shortening. [DOI] 10.1080/15321819.2021.2004162
Molecular Mechanisms of Alveolar Epithelial Stem Cell Senescence and Senescence-Associated Differentiation Disorders in Pulmonary Fibrosis폐 섬유증에서 폐포 상피 줄기 세포 노화 및 노화 관련 분화 장애의 분자 기전Review Published on 2022-03-032022-09-11 Journal: Cells [Category] MERS, SARS, 유전자 메커니즘, 진단, [키워드] accelerated alveolar caused Cell cell senescence cellular senescence COVID-19 Degradation developmental differentiation disorder disrupt DNA damage DNA damage response dysfunction epithelial fibrosis followed by framework Idiopathic pulmonary fibrosis induce inhibiting inhibitor Intervention IPF low-grade inflammation mechanism molecular mechanism molecular mechanisms OIS oncogene pathway Premature Protein pulmonary pulmonary fibrosis replicative replicative senescence reported reverse transcriptase RNA SARS-CoV-2 viral infection senescence senescent cell senescent cells STEM stem cell suppression susceptibility telomerase telomerase and telomeres. telomeres TERC TERT TGF TGF-β TGF-β signalling TPP1 transcriptase Viral viral infection [DOI] 10.3390/cells11050877 PMC 바로가기 [Article Type] Review
Distinct Patterns of HBV Integration and TERT Alterations between in Tumor and Non-Tumor Tissue in Patients with Hepatocellular CarcinomaArticle Published on 2021-06-302023-06-03 Journal: International Journal of Molecular Sciences [Category] B형 간염, [키워드] Hepatitis B virus Liver cancer Point mutation telomerase virus integration [DOI] 10.3390/ijms22137056 PMC 바로가기 [Article Type] Article
Cellular aging dynamics after acute malaria infection: A 12‐month longitudinal study급성 말라리아 감염 후 세포 노화 역학: 12개월 종단 연구Original Article Published on 2017-11-162024-08-12 Journal: Aging Cell [Category] 말라리아, [키워드] CDKN2A cellular aging malaria Plasmodium falciparum telomerase telomeres [DOI] 10.1111/acel.12702 PMC 바로가기 [Article Type] Original Article
Ku Binding on Telomeres Occurs at Sites Distal from the Physical Chromosome Ends텔로미어의 Ku 결합은 물리적 염색체 말단에서 먼 부위에서 발생Research Article Published on 2016-12-082022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] association bind binding Cancer caused cells chromatin chromosome chromosomes complex difficulty DNA DNA binding DNA break DNA breaks DNA replication double-stranded elements elongation End facilitate finding followed by function generate Genome hallmark independent induce interstitial lead mechanism NHEJ non-homologous occur physical predict Previous studies protein-protein interaction proximal reduce Region repair Replication replication fork reported Site solution telomerase telomere telomeres transition turn yeast [DOI] 10.1371/journal.pgen.1006479 PMC 바로가기 [Article Type] Research Article
Establishment of feline intestinal epithelial cell cultures for the propagation and study of feline enteric coronavirusesResearch Published on 2013-08-212022-10-28 Journal: Veterinary Research [Category] Coronavirus, MERS, [키워드] addition Cell culture circulating compared coronavirus Culture cultures death different epithelial evaluated Feline infectious peritonitis growth healthy Infection infectious inoculated intestinal intestinal epithelial cells lack mutant no infection observation replicated replication capacity Research serotype significantly more strain Strains susceptible susceptible cell Suspension SV40 telomerase tissue tissue homogenates virulent virus was done [DOI] 10.1186/1297-9716-44-71 PMC 바로가기 [Article Type] Research