Production of functional oocytes requires maternally expressed PIWI genes and piRNAs in golden hamsters Research Published on 2021-09-062022-10-05 Journal: Nature cell biology [Category] 유전자 메커니즘, [키워드] adaptive assumption Cell conserved deficiency Disruption DNA methylation expressed female functional Gene Expression Genes Genome hamster hamsters humans involved lack male mammalian mechanism Oocyte oocytes pathway Piwi piwi-interacting RNA PIWIL1 PIWIL3 Production transposon was reduced [DOI] 10.1038/s41556-021-00745-3 [Article Type] Research
Generation of WAe001-A-58 human embryonic stem cell line with inducible expression of the SARS-CoV-2 nucleocapsid proteinSARS-CoV-2 뉴클레오캡시드 단백질의 유도성 발현을 갖는 WAe001-A-58 인간 배아 줄기 세포주의 생성Article Published on 2021-05-012022-09-11 Journal: Stem cell research [Category] SARS, 치료법, [키워드] activate celebrex cell line cell types Comorbidities Comorbidity COVID-19 death discharged embryonic embryonic stem cell expression Generation hospitalized COVID-19 patient hospitalized COVID-19 patients Host karyotype morphology multiple organ multiple organs nucleocapsid nucleocapsid protein PGE prostaglandin prostaglandin E Protein SARS-CoV SARS-CoV-2 SARS-CoV-2 N protein stem cell suggested the SARS-CoV-2 Transcription transcriptionally transposon Treatment [DOI] 10.1016/j.scr.2021.102197 PMC 바로가기 [Article Type] Article
An Africa-wide genomic evolution of insecticide resistance in the malaria vector Anopheles funestus involves selective sweeps, copy number variations, gene conversion and transposons말라리아 매개체 Anopheles funestus의 살충제 저항성의 아프리카 전역 게놈 진화에는 선택적 스윕, 복제 수 변이, 유전자 전환 및 트랜스포존이 포함됩니다Research Article Published on 2020-06-042022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, 말라리아, [키워드] alleles Analysis Anophele approach bed net complex copy number cytochrome P450 driven by Effectiveness Evidence evidence of Evolution exhibited gene conversion gene flow Genes genetic diversity genomic genomic change genomic region glutathione greater haplotypes highlighting independent insecticide insecticides insertion Intervention Local loci locus malaria malaria control malaria vector management metabolic Metabolic resistance molecular molecular evolution Multiple performed Population pyrethroid respond risk selection pressure selective sweep selective sweeps signature Spread Temporal transposon Variation variations vector control whole genome [DOI] 10.1371/journal.pgen.1008822 PMC 바로가기 [Article Type] Research Article
Long transposon-rich centromeres in an oomycete reveal divergence of centromere features in Stramenopila-Alveolata-Rhizaria lineages난균류의 긴 트랜스포존이 풍부한 중심체는 Stramenopila-Alveolata-Rhizaria 계통에서 중심체 기능의 발산을 나타냅니다.Research Article Published on 2020-03-092022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Aneuploidy assembly binding Cell cell division centromere ChIP-seq chromatin chromatin immunoprecipitation chromosomal chromosomal region chromosome segregation Cluster CoLT criterion diatoms Divergence DNA sequence DNA sequences element eukaryotes Evolution facilitated feature focus followed by Frequency functional fungal Genome genome assembly genome organization genomes help heterochromatin identification identify knowledge lack life life stage Lineage Long microorganism microorganisms Modification MOST nuclear organism Plasmodium Plasmodium falciparum platform provide reference strain Region regions reveal SAR Sequencing subset transcribed transposon turn [DOI] 10.1371/journal.pgen.1008646 PMC 바로가기 [Article Type] Research Article
Recombinant Hepatitis E Viruses Harboring Tags in the ORF1 ProteinArticle Published on 2019-07-172023-08-30 Journal: Journal of Virology [Category] E형 간염, [키워드] HEV open reading frame 1 protein Positive-strand RNA virus replicase replication complex replicon transposon viral life cycle [DOI] 10.1128/JVI.00459-19 PMC 바로가기
Essential gene deletions producing gigantic bacteria거대 박테리아를 생성하는 필수 유전자 결실Research Article Published on 2019-06-102022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] accelerated Acinetobacter Analysis antibiotic Antibiotics Bacteria Bacterial Bacterial infections blocked Cell cell wall cell wall synthesis cells cleave consequence conserved creating dead dead cell dead cells deleted Deletion eliminating enzyme Essential feature function functions Genetic Giant giant cell giant cells help hydrolysis identify inactivated independent life lysed lytic transglycosylase mutant mutants Mutation natural transformation osmotic overcome overlapping pathogenic pathway peptide peptidoglycan polymerization precursor predicted produced producing required respond responsible resulting sacculus targets the cell the dead Tn-seq transposon Treatment [DOI] 10.1371/journal.pgen.1008195 PMC 바로가기 [Article Type] Research Article
CDI/CDS system-encoding genes of Burkholderia thailandensis are located in a mobile genetic element that defines a new class of transposonBurkholderia thailandensis의 CDI/CDS 시스템 인코딩 유전자는 새로운 종류의 트랜스포존을 정의하는 이동성 유전 요소에 있습니다.Research Article Published on 2019-01-072022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] acquisition allele Bacteria Bacterial Burkholderia CDS Cell cells Characteristics chromosome Community community development composed cooperation Critical DNA dsDNA element Escherichia coli Evidence facilitate fitness functional Genes genes encoding Genetic genetic material growth helping immune Immunity induce inhibit insertion insertion sequence Interaction Intercellular communication involved killing lack left mechanism microbial Microbial communities Mobility occur Organisms phenomenon Phenotypes Propagation Protein provide reaction required self sequence sequences Signaling Support synthesis target cell transposon turn [DOI] 10.1371/journal.pgen.1007883 PMC 바로가기 [Article Type] Research Article
Cell envelope stress in mycobacteria is regulated by the novel signal transduction ATPase IniR in response to trehalose마이코박테리아의 세포 외피 스트레스는 트레할로스에 대한 반응으로 새로운 신호 전달 ATPase IniR에 의해 조절됩니다Research Article Published on 2017-12-272022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Activation activator Affect assembly ATPase Author BAC bacterial cell biogenesis cascade Cell cell envelope cell wall complex compounds damaged defect domain domains drug ethambutol experiment explain exposure to family Gram-negative bacteria homologue identify include induce inducer integrity involved isoniazid latter gene Lipid lipids locus mechanism Mutagenesis mutant mutants mutations mycobacteria mycobacterial Mycobacterium operon overexpression pathway promoter PROTECT regulated Regulation regulator Regulatory regulatory gene respond RNAseq shown signal Signal transduction Signaling Stress stress response sugar sugars the cell transcriptional regulator transposon trehalose Tuberculosis understanding unique [DOI] 10.1371/journal.pgen.1007131 PMC 바로가기 [Article Type] Research Article
The nucleoid occlusion protein SlmA is a direct transcriptional activator of chitobiose utilization in Vibrio choleraenucleoid occlusion protein SlmA는 Vibrio cholerae에서 키토비오스 활용의 직접적인 전사 활성제입니다.Research Article Published on 2017-07-062022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Activation activity addition aquatic environment bind Catabolism cause Cell cell division ChiS chitin chitobiose cholera cholerae composed Critical disaccharide disease disparate disrupt downstream drinking water Evolution expression function Gene regulation gene transfer horizontal gene Horizontal gene transfer identify implicated in vivo Interaction involved locus mechanism member mutant pathogen persistence Point mutation point mutations promoter Protein Proteins regulated Regulation regulator required TetR the marine transcriptional transcriptional activation transcriptional regulator transfer transposon utilization Vibrio cholerae water [DOI] 10.1371/journal.pgen.1006877 PMC 바로가기 [Article Type] Research Article
Antimicrobial resistance in zoonotic nontyphoidal Salmonella: an alarming trend?인수공통 비장티푸스성 살모넬라의 항균제 내성: 우려스러운 추세인가?Review Published on 2016-12-012023-06-03 Journal: Clinical microbiology and infection : the official [Category] 살모넬라증, 조류인플루엔자, [키워드] food-borne pathogen Horizontal gene transfer Plasmid transposon zoonosis [DOI] 10.1016/j.cmi.2016.07.033 [Article Type] Review