Breast Cancer: Extracellular Matrix and Microbiome InteractionsReview Published on 2024-06-302024-09-05 Journal: International Journal of Molecular Sciences [Category] update2024, [키워드] Breast cancer Extracellular matrix Microbiome tumorigenesis [DOI] 10.3390/ijms25137226 PMC 바로가기 [Article Type] Review
Hepatitis B surface antigen expression impairs endoplasmic reticulum stress-related autophagic flux by decreasing LAMP2Research Article Published on 2024-01-282024-09-05 Journal: JHEP Reports [Category] update2024, [키워드] cellular homeostasis HBV surface protein incomplete autophagy Liver cancer lysosome tumorigenesis [DOI] 10.1016/j.jhepr.2024.101012 PMC 바로가기 [Article Type] Research Article
Exploring the promising potential of induced pluripotent stem cells in cancer research and therapyarticle Published on 2023-11-282024-09-05 Journal: Molecular Cancer [Category] update2024, [키워드] immunotherapies induced pluripotent stem cells Personalized medicine regenerative medicine therapy tumorigenesis [DOI] 10.1186/s12943-023-01873-0 PMC 바로가기 [Article Type] article
Intratumoural microbiota: from theory to clinical applicationarticle Published on 2023-06-282024-09-05 Journal: Cell Communication and Signaling : CCS [Category] update2024, [키워드] anticancer treatment Intratumoural bacteria tumorigenesis [DOI] 10.1186/s12964-023-01134-z PMC 바로가기 [Article Type] article
eIF3d: A driver of noncanonical cap–dependent translation of specific mRNAs and a trigger of biological/pathological processesarticle Published on 2023-03-292024-09-05 Journal: Brain stimulation [Category] update2024, [키워드] cap-dependent translation drug resistance EIF3D signaling pathway tumorigenesis [DOI] 10.1016/j.jbc.2023.104658 PMC 바로가기 [Article Type] article
The regulation of ISG20 expression on SARS-CoV-2 infection in cancer patients and healthy individualsArticle Published on 2022-09-132022-11-15 Journal: Frontiers in Immunology [Category] SARS, 변종, 치료제, [키워드] analyzed anti-SARS-CoV-2 anticancer Bone marrow Cancer cancer cell cancer cell lines cancer patient Cancer patients chemokine combating cordycepin cordycepin (CD). correlated COVID-19 COVID-19 pandemic domain exhibited expression functional healthy healthy individual highest immune Immune cell infiltration immune infiltration individuals information inhibit Invasion ISG20 ISG20 expression isoform less Lymphocytes lymphoid tissues marker Methylation MHC molecule mRNA expression mutant N6 N6-dimethyladenosine (m 6 2A) outcome overexpression promoter receptors Regulation SARS-CoV-2 SARS-COV-2 infection significantly significantly increased significantly lower small molecule survival survival rate susceptibility the median therapeutic potential tissue tissues traditional Chinese medicines treat tumorigenesis underlie virus were used [DOI] 10.3389/fimmu.2022.958898 PMC 바로가기
Senescence and cancer — role and therapeutic opportunities Reviews Published on 2022-08-312022-10-05 Journal: Nature Reviews Clinical Oncology [Category] 변종, [키워드] anticancer benefit Cancer Cell cell cycle arrest change Clinical findings condition demonstrated Factor function involved macromolecular mechanism outcome Patients with cancer phenotype pro-inflammatory review senescence senescent cell therapeutic therapy translational tumorigenesis [DOI] 10.1038/s41571-022-00668-4 [Article Type] Reviews
USP22 controls type III interferon signaling and SARS-CoV-2 infection through activation of STINGUSP22는 STING의 활성화를 통해 III형 인터페론 신호 전달 및 SARS-CoV-2 감염을 제어합니다Article Published on 2022-08-062022-09-11 Journal: Cell Death & Disease [Category] SARS, 유전자 메커니즘, 치료제, [키워드] absence Activation Antiviral basal causative agent Control COVID-19 pandemic de novo Defense enzyme epithelial cells exogenous IFN expression function Host identify IFN IFN signaling IFN-stimulated gene IFN-stimulated genes IFN-λ IFNs implication interferons interferons (IFNs interferons (IFNs) intestinal epithelial cell involved ISG ISGs long-lasting Particles pattern Pattern recognition Pattern recognition receptors PRRs receptor reversed SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections secretion Signaling STAT Stat1 STING tumorigenesis Type Type III IFN Type III IFNs type III interferon USP22 viral infection viral replication [DOI] 10.1038/s41419-022-05124-w PMC 바로가기 [Article Type] Article
Hypoxia signaling in human health and diseases: implications and prospects for therapeutics Reviews Published on 2022-07-072022-10-05 Journal: Signal Transduction and Targeted Therapy [Category] 신약개발, [키워드] Activation addition biological processes Cancer Cell cell metabolism cell proliferation cellular pathways change Chronic diseases disease Diseases downstream gene drugs Endoplasmic reticulum ERK expression Extracellular Factor Glycolysis Health hypoxia immune response implication Infection interact involved kinase mammalian cells mechanism Metastasis microbe Molecular oxygen NF-κB nuclear oxygen pathogenic pathway question Rapamycin reaction regulate respond responses Signaling Stress subsequent therapeutic therapeutic target tumorigenesis [DOI] 10.1038/s41392-022-01080-1 [Article Type] Reviews
LncRNA TMPO-AS1 promotes esophageal squamous cell carcinoma progression by forming biomolecular condensates with FUS and p300 to regulate TMPO transcription Research Published on 2022-06-272022-10-05 Journal: Experimental & Molecular Medicine [Category] 바이오마커, [키워드] activate Cell cell proliferation cells China Combination experiment expression functional FUS fused in vivo lncRNA Long lysine malignant disease mechanism Metastasis noncoding RNA overexpressed performed positively correlated Potential biomarker progression proliferation promote promoter recruited regulate required RNA significantly siRNA survival targeting therapeutic target TMPO TMPO-AS1 Transcription tumor growth tumor progression tumorigenesis upregulated [DOI] 10.1038/s12276-022-00791-3 [Article Type] Research