Broad and durable antibody response after vaccination with inactivated SARS-CoV-2 in individuals with a history of 2003 SARS-CoV infection2003년 SARS-CoV 감염 이력이 있는 개인에서 비활성화된 SARS-CoV-2 백신 접종 후 광범위하고 지속적인 항체 반응Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, [키워드] activity antibody Antibody Response Antigen Beta Delta dosage greater Heterologous heterologous immunization inactivated Inactivated vaccine individual naïve vaccinees neutralizing activities Neutralizing activity nucleoprotein omicron pseudovirus pseudoviruses RBD of SARS-CoV-2 receiving SARS-CoV SARS-CoV infection SARS-CoV-2 SARS-CoV-2 vaccine SARS-related coronaviruses second vaccination significantly higher suggested undetectable Universal vaccine vaccination Vaccine vaccinee vaccinees variant variants virus viruses were infected Wuhan [DOI] 10.1080/22221751.2022.2076613 PMC 바로가기 [Article Type] Article
Reduced neutralization of SARS-CoV-2 Omicron variant by BNT162b2 vaccinees’ sera: a preliminary evaluationBNT162b2 백신접종자 혈청에 의한 SARS-CoV-2 오미크론 변이체 중화 감소: 예비 평가Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] BNT162b2 neutralization omicron SARS-CoV-2 vaccinee variant [DOI] 10.1080/22221751.2022.2045878 PMC 바로가기 [Article Type] Article
Comparable antigen-specific T cell responses in vaccinees with diverse humoral immune responses after the primary and booster BBIBP-CorV vaccinationArticle Published on 2022-12-012022-11-15 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 진단, 치료기술, 치료제, [키워드] Anti-spike Antibody Response B cell B cell responses BBIBP-CorV booster booster vaccination CD4 CD8 comparable COVID-19 COVID-19 vaccines de novo demonstrated detectable dramatic increase Epidemic exhibited Features humoral immune response Humoral immunity humoral responses interferon-γ Neutralizing antibodies omicron remained S protein SARS-CoV-2 SARS-COV-2 infection serotype Severe case Shanghai significantly T cell T cell response T cell responses T cell responses. Th1 cytokine vaccination vaccinee vaccinees wild type [DOI] 10.1080/22221751.2022.2130101 PMC 바로가기
Analysis of anti-SARS-CoV-2 Omicron-neutralizing antibody titers in different vaccinated and unvaccinated convalescent plasma sourcesArticle Published on 2022-10-292022-11-15 Journal: Nature Communications [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] anti-SARS-CoV-2 Antibody titer CCP collected convalescent plasma COVID-19 Donor dose effective geometric geometric mean titer Immune escape Immunocompromised implication Infection lesson monoclonal antibodies monoclonal antibody mRNA vaccine neutralization neutralize Neutralizing Neutralizing antibody titer omicron Outpatient pandemic plasma plasma activity provide recipients reduction representing SARS-CoV-2 variant sera subject therapeutic Therapies uninfected vaccinee variant variants of concern [DOI] 10.1038/s41467-022-33864-y PMC 바로가기
Correlation of SARS-CoV-2 Viral Neutralizing Antibody Titers with Anti-Spike Antibodies and ACE-2 Inhibition among Vaccinated IndividualsArticle Published on 2022-10-262022-11-15 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 진단, [키워드] ACE-2 ACE2 ACE2 binding analyzed Angiotensin converting enzyme-2 Anti-RBD IgG Anti-spike anti-spike antibody anti-Spike IgG antibody binding blood collection BNT162b2 calculated collected Concentration correlated correlation correlation coefficient correlation coefficients COVID-19 COVID-19 antibody demonstrated dosing interval examined Fisher group groups IgG individual inhibition interval intervals labor-intensive measure mRNA mRNA-1273 vaccines Neutralizing antibodies neutralizing antibody Neutralizing antibody titer neutralizing antibody titers NTD Participants performed RBD Sample SARS-CoV-2 Secondary analyses Spearman correlation coefficient subgroup tested the median the vaccine titer vaccinated individual vaccination Vaccine vaccinee vaccinees Validity viral neutralization wild-type with COVID-19 women [DOI] 10.1128/spectrum.01315-22 PMC 바로가기
Longitudinal Serological Surveillance for COVID-19 Antibodies after Infection and VaccinationArticle Published on 2022-10-262022-11-15 Journal: Microbiology Spectrum [Category] 진단, [키워드] Ad26.COV2.S vaccine addition analyzed Anti-spike anti-spike antibody antibody Antibody titer association booster vaccination booster vaccinations Breakthrough infection breakthrough infections can be used Characteristics Cohort Complete conducted Confirmed COVID-19 infection COVID-19 COVID-19 infection COVID-19 infections COVID-19 pandemic Defense evaluate event events exhibited Health care system immunization include Infection infection risk infections Infectious disease information longitudinal mRNA mRNA vaccines occurred participant positively correlated Prevalence receive receiving reported Research risk significantly social distancing subject subjects the timing threshold vaccinated individuals vaccination vaccination responses Vaccination strategy vaccinee vaccinees [DOI] 10.1128/spectrum.02026-22 PMC 바로가기
Hybrid Immunity Shifts the Fc-Effector Quality of SARS-CoV-2 mRNA Vaccine-Induced ImmunityArticle Published on 2022-10-262022-11-15 Journal: mBio [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] accelerate antibody antibody function Antibody Response Antibody titer Antigen binding antibody Combination comparable conserved COVID-19 cross-reactivity disease dose expected Fc-receptors first dose function functional functions humoral immune response hybrid Hybrid immunity immune immune priming Immunity immunization immunodominance increases in indicate individual individuals Infection magnitude modify mRNA mRNA vaccination mRNA vaccine mRNA vaccines neutralizing antibody offer Quality receive recent Region remained resulting robust SARS-CoV-2 second dose selective serology shift spike subsequent symptomatic T cell the SARS-CoV-2 the Spike unique vaccination Vaccine vaccine-induced immune response vaccinee Vaccines variants of concern virus while [DOI] 10.1128/mbio.01647-22 PMC 바로가기
Evaluation of the systemic and mucosal immune response induced by COVID-19 and the BNT162b2 mRNA vaccine for SARS-CoV-2Article Published on 2022-10-182022-11-15 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, [키워드] antibody antibody production appear BNT162b2 BNT162b2 mRNA vaccine convalescent correlated COVID-19 COVID-19 patients decrease detectable eight elicit functional generate Heterologous humoral humoral immune response Immunity immunization increase induce marker mRNA vaccination mRNA vaccine mucosal mucosal immune NAb Neutralizing neutralizing capacity of BNT162b2 omicron peaked progression proportion protective immune response RBD RBD-binding antibody reduced Saliva SARS-CoV-2 second dose second vaccination sera significantly Spike protein subsequent the RBD the S1 subunit the SARS-CoV-2 vaccinated individual vaccination Vaccine vaccinee vaccinees variant virus neutralizing titers VoC VOCs wildtype [DOI] 10.1371/journal.pone.0263861 PMC 바로가기
Cellular interferon-gamma and interleukin-2 responses to SARS-CoV-2 structural proteins are broader and higher in those vaccinated after SARS-CoV-2 infection compared to vaccinees without prior SARS-CoV-2 infectionArticle Published on 2022-10-172022-11-15 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 진단, [키워드] assays BNT162b2 BNT162b2 vaccine class correlated demonstrated develop dose doses epitope exhibited Frequency greater healthcare worker healthy IFN-γ IgG response IL-2 IL2 Immunity individual infected with SARS-CoV-2 Infection Interferon-gamma interleukin-2 magnitude Moderna mRNA-1273 vaccine mononuclear cell mRNA-1273 N and M nine participant Participants PCR testing peptide Peripheral blood Pfizer-BioNTech positive Post-infection Proteins proteome repeated responders response responses against robust S glycoprotein S1 and S2 S2 subunit SARS-CoV-2 SARS-COV-2 infection structural protein subunit subunits T cell response T-cell Response the SARS-CoV-2 uninfected vaccination vaccinee was determined were expressed with COVID-19 [DOI] 10.1371/journal.pone.0276241 PMC 바로가기
Comparison of the kinetics and magnitude of antibody responses to different SARS-CoV-2 proteins in Sinopharm/BBIBP-CorV vaccinees following the BNT162b2 booster or natural infectionArticle Published on 2022-10-132022-11-15 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 진단, [키워드] ACE2 anti-RBD antibodies antibody Antibody Response BNT162b2 booster Cohort dose Frequency highest IgG antibody immune response implication individual infected individual Infection investigated lowest magnitude natural infection persistence post vaccination Protein receive remained robust S1 and S2 SARS-CoV-2 protein second dose significantly higher Sinopharm subsequent the N protein the RBD the SARS-CoV-2 virus total antibody uninfected vaccinee vaccinees were infected [DOI] 10.1371/journal.pone.0274845 PMC 바로가기