A six-month study of anti-SARS-CoV-2 BNT162b2 mRNA vaccination: A comparative analysis of essential trace elements and anti-RBD IgG sera levelsArticle Published on 2022-12-012022-11-15 Journal: Journal of trace elements in medicine and biology [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] (Post)vaccinal immunity adaptive Analysis analyzed Anti-RBD IgG anti-SARS-CoV-2 anti-SARS-CoV-2 IgG Antibody detection Antibody titers association biochemical BNT162b2 mRNA BNT162b2 mRNA vaccine changes in Concentration Cu Effect elevated Essential Essential trace elements expressed female follow-up period glycoprotein healthy HEK-293 human serum IgG antibody Immunity immunization investigated mRNA vaccine not affected observation period produced producing Protein purified RBD Receptor binding domain remained SARS-CoV-2 sera serum specific IgG antibody spike T cells Total Trace element vaccination Vaccine Volunteer women Zn [DOI] 10.1016/j.jtemb.2022.127079 PMC 바로가기
New insights into antibody levels against SARS-CoV-2 for healthcare personnel vaccinated with tozinameran (Comirnaty)Article Published on 2022-11-032022-11-15 Journal: PLoS ONE [Category] SARS, 진단, [키워드] activated addition addressed administration Alto Andújar antibody booster dose COVID-19 determine Dilution Elecsy Evolution exhibited Germany Guadalquivir healthcare personnel Healthcare professional humoral IgG in vitro infected patients material Neutralizing antibodies New non-infected pandemic platform Roche SARS-CoV-2 SARS-CoV-2 vaccine second dose serum sample Spike protein subject Thermo Fisher Scientific titer total antibody vaccination Vaccine Volunteer volunteers [DOI] 10.1371/journal.pone.0276968 PMC 바로가기
The impact of COVID-19 on implementation of mass testing, treatment and tracking of malaria in rural communities in Ghana: A qualitative study가나 농촌 지역사회에서 말라리아 대량 검사, 치료 및 추적 실시에 대한 코로나19의 영향: 질적 연구Article Published on 2022-10-132022-11-15 Journal: PLoS ONE [Category] 말라리아, 진단, [키워드] addition affected analysed Analysis children Community Complication conducted Coverage COVID-19 COVID-19 pandemic Effect eight English finding group Health health worker identify implementation increase in Intervention introduced malaria mass methodology observation pandemic parent participant public health respond responsible Transcription translated treat Treatment Volunteer volunteers was used were recorded [DOI] 10.1371/journal.pone.0275976 PMC 바로가기
Differences in the immune response elicited by two immunization schedules with an inactivated SARS-CoV-2 vaccine in a randomized phase 3 clinical trialArticle Published on 2022-10-132022-11-15 Journal: eLife [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] Activation acute respiratory syndrome antibody approved blood sample Brazil CD4 cellular Chilean China circulating antibodies clinical clinical trial Concentration CoronaVac coronavirus coronavirus disease correlation COVID-19 difference dose Efficacy elicited Emergency use enrolled evaluate evaluated exhibited expression flow cytometry healthy Human humoral immune response humoral immune responses IFN-γ immune response immunization immunogenicity data immunology inactivated Indonesia Inflammation interferon marker Medicine Ministry of Health mononuclear cell multicenter neutralizing antibody neutralizing capacity pandemic PBMCs performed Peripheral blood Phase 3 phase 3 clinical trial phase 3 trial Production progression promote Randomized reported robust Sample SARS-CoV-2 SARS-CoV-2 vaccine secretion separated single center Stimulation T cell Trial Turkey Vaccine Vaccines variants of concern virus VOCs Volunteer were assessed [DOI] 10.7554/eLife.81477 PMC 바로가기
An isothermal lab-on-phone test for easy molecular diagnosis of SARS-CoV-2 near patients and in less than 1 hourArticle Published on 2022-10-012022-11-15 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, [키워드] amplification B.1.1.529 B.1.351 B.1.617.2 Beta Clinical management clinical samples conducted COVID-19 COVID-19 pandemic cross-reaction Delta demonstrated e genes gold standard Infection isothermal isothermal amplification LAMP assay less Molecular diagnosis nasopharyngeal nucleic acid amplification techniques omicron Patient point of care point-of-care point-of-care testing Population screening predominant Real-time PCR respiratory pathogen SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant sensitivity specificity Symptom Transmission Volunteer [DOI] 10.1016/j.ijid.2022.07.042 PMC 바로가기
Seroepidemiological study of factors affecting anti-spike IgG antibody titers after a two-dose mRNA COVID-19 vaccination in 3744 healthy Japanese volunteersArticle Published on 2022-09-292022-11-15 Journal: Scientific Reports [Category] 진단, [키워드] 1.26 Adverse reaction affecting age anti-S anti-S antibody anti-S IgG anti-Spike IgG antibody Antibody titer Antibody titers BNT162b2 vaccine conducted COVID-19 vaccination cross-sectional dose Effect elapsed Factor Factors female females Gender healthy healthy volunteer identify IgG antibody titer immunosuppressants immunosuppressive IQR Japanese magnitude median age mRNA mRNA-1273 mRNA-1273 vaccine Multiple positive questionnaire SARS-COV-2 infection significantly smoking tested the vaccine therapy vaccination Vaccine Volunteer [DOI] 10.1038/s41598-022-20747-x PMC 바로가기
Metabolomics-based investigation of SARS-CoV-2 vaccination (Sinovac) reveals an immune-dependent metabolite biomarkerArticle Published on 2022-09-282022-11-15 Journal: Frontiers in Immunology [Category] SARS, 바이오마커, 변종, 진단, [키워드] analyses Analysis antibodies and cytokines antibody association AUC Biomarker boost butanoate collected COVID-19 COVID-19 vaccine Cytokines determine effective fatality FDR Fold change GABA Glutamate greater help Host host immunity IgA IgG IgM immune Immunity IMPROVE individual indole Infection L-glutamic acid metabolism metabolite metabolome metabolomic metabolomic analysis metabolomics mutant strain mutated Pathways positive pre-vaccination provide respond reveal SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 virus infection sera serum serum antibody Sinovac Spread Taurine vaccination Vaccine VIP Volunteer was performed [DOI] 10.3389/fimmu.2022.954801 PMC 바로가기
Humoral response and neutralising capacity at 6 months post-vaccination against COVID-19 among institutionalised older adults in ArgentinaArticle Published on 2022-09-262022-11-15 Journal: Frontiers in Immunology [Category] SARS, 진단, [키워드] affected age aging adults Anti-spike anti-Spike IgG antibody AZD1222 B.1 BBIBP-CorV Buenos Aires Cohort Complete correlation COVID-19 COVID-19 pandemic death different time point dose elicited evaluated Evidence evidenced exhibited Gender highlighting hospitalisation humoral Humoral response IgG titer IgG titers initial management neutralising Neutralising activity Neutralising Antibodies neutralising antibodies. Older omicron pandemic participant Participants plasma sample platform provide public health resulting SARS-CoV-2 significantly higher Sputnik-V Strong vaccination vaccination schedule vaccine platform Volunteer [DOI] 10.3389/fimmu.2022.992370 PMC 바로가기
Humoral immunoresponse elicited against an adenoviral-based SARS-CoV-2 coronavirus vaccine in elderly patientsArticle Published on 2022-09-212022-11-15 Journal: Aging (Albany NY) [Category] SARS, 진단, 치료기술, [키워드] Ad26 Ad5 analyzed anti-RBD anti-RBD ELISA anti-RBD IgG antibodies antibody Cohort COVID-19 detectable dose dropped effective vaccine elderly Elderly patient elicit elicited Evolution expected females Gam-COVID-Vac Gender Genome Heterologous highest humoral immune response IgG IgG titer immune response immune responses immune system individual median post vaccination reached remained robust SARS-CoV-2 SARS-CoV-2 coronavirus SARS-COV-2 infection Sequencing seroconversion rate significant decrease significant difference specific antibody the SARS-CoV-2 the Spike Vaccine viral genome virus Volunteer [DOI] 10.18632/aging.204299 PMC 바로가기
Is IFN expression by NK cells a hallmark of severe COVID-19?Research article Published on 2022-09-012022-10-05 Journal: Cytokine [Category] 변종, 치료기술, 치료제, [키워드] addition CD107a clinical form contribute CoV COVID-19 cytolytic cytotoxic activity Cytotoxic granules decrease Defense disease elicited Express expression form Frequency Granule granzyme B groups hallmark Host IFN IFN-α IFN-γ immune responses immune system individual Innate immunity interferons involved Ki-67 Killer cell mechanism Mild natural Natural killers NK cell NK cells pathogenesis of COVID-19 PBMC PBMCs peptide pool profile question recovered COVID-19 patient reduced SARS-CoV-2 severe COVID-19 severity significant increase spike the disease the healthy viruses Volunteer [DOI] 10.1016/j.cyto.2022.155971 [Article Type] Research article