Lymphopenia predicted illness severity and recovery in patients with COVID-19: A single-center, retrospective study림프구감소증은 COVID-19 환자의 질병 중증도 및 회복을 예측했습니다: 단일 센터, 후향적 연구Research Article Published on 2020-11-182022-08-13 Journal: PLoS ONE [Category] Biochemistry, COVID-19, MERS, [키워드] Admission C-reactive protein C-reactive protein (CRP Chest chest radiographs China clinical Clinical significance Coronary heart disease correlated COVID-19 CRP demonstrated disease disease severity duration of hospitalization enrolled Eosinopenia heart disease hospital hypertension Illness severity investigated Laboratory leukopenia lymphocyte Lymphocyte count lymphopenia median age MONITOR on admission outbreak outcome pandemic Patient Pneumonia predicted Predictive Predictive value Retrospective study SARS-CoV-2 severe cases severity single-center Treatment [DOI] 10.1371/journal.pone.0241659 PMC 바로가기 [Article Type] Research Article
Sensitivity evaluation of 2019 novel coronavirus (SARS-CoV-2) RT-PCR detection kits and strategy to reduce false negative2019 신종 코로나바이러스(SARS-CoV-2) RT-PCR 검출 키트의 민감도 평가 및 위음성 감소 전략Research Article Published on 2020-11-182022-08-13 Journal: PLoS ONE [Category] Biochemistry, COVID-19, SARS, [키워드] 2019 novel coronavirus addition asymptomatic patient asymptomatic patients community transmission Concentration COVID-19 disease criteria Detection sensitivity Diagnosis differential diagnosis discharge discharged patient discharged patients Early detection Epidemic evaluated Evidence false-negative false-negative results increase indicated initial less low viral load patients lowest Molecular diagnosis Mutation nucleic acid Nucleic acid detection nucleic acid RT-PCR test ORF1ab gene patients Prevention and control recommendation reduce respiratory respiratory infection respiratory infections RT-PCR detection RT-PCR test SARS-CoV-2 seeking specificity target validation kit Viral Viral load [DOI] 10.1371/journal.pone.0241469 PMC 바로가기 [Article Type] Research Article
Factors associated with disease severity and mortality among patients with COVID-19: A systematic review and meta-analysisCOVID-19 환자의 질병 중증도 및 사망률과 관련된 요인: 체계적인 검토 및 메타 분석Research Article Published on 2020-11-182022-08-13 Journal: PLoS ONE [Category] Biochemistry, COVID-19, MERS, [키워드] 95%CI Analysis article assist C-reactive protein Clinical characteristics congestive heart failure coronavirus coronavirus disease COVID-19 cut-off D-dimer data extraction database determine diabete diabetes died disease disease severity Dyspnea elevated English language Factor Gender greater heart failure higher odd higher odds hypertension imperative inception increasing age Laboratory Leukocytosis lung involvement lymphopenia male Meta-analysis Mortality observational studies observational study Patient patients patients with COVID-19 performed radiological resource Result risk searched severe disease severity systematic review those who survived understanding WHO [DOI] 10.1371/journal.pone.0241541 PMC 바로가기 [Article Type] Research Article
Incidence and risk factors of kidney impairment on patients with COVID-19: A meta-analysis of 10180 patientsCOVID-19 환자에서 신장 손상의 발생률 및 위험 요소: 10180명의 환자에 대한 메타 분석Research Article Published on 2020-11-162022-08-13 Journal: PLoS ONE [Category] Biochemistry, COVID-19, MERS, SARS, [키워드] Acute kidney injury AKI Analysis association Biomarker Blood urea nitrogen clinical manifestation clinical manifestations COVID-19 COVID-19 infection COVID-19 patient COVID-19 patients creatinine D-dimer damage database eligible evaluate evaluated Evidence evidence of gastrointestinal system Hematuria heterogeneity Impact impairment incidence kidney kidney dysfunction Kidney injury Laboratory laboratory feature mean differences medRxiv Meta-analysis nitrogen non-ICU Novel coronavirus pandemic Patient patients patients with COVID-19 Prevalence Proteinuria researcher respiratory Result risk factor searched serum creatinine shown the mean urea [DOI] 10.1371/journal.pone.0241953 PMC 바로가기 [Article Type] Research Article
Epidemiology, risk factors and clinical course of SARS-CoV-2 infected patients in a Swiss university hospital: An observational retrospective study스위스 대학 병원에서 SARS-CoV-2 감염 환자의 역학, 위험 요인 및 임상 경과: 관찰 후향적 연구Research Article Published on 2020-11-132022-08-13 Journal: PLoS ONE [Category] Biochemistry, COVID-19, MERS, SARS, [키워드] 95% CI Admission age Clinical course clinician COVID-19 patient CRP Electronic health records Epidemiology European greater help high risk hospital identify IQR Laboratory male Male sex mechanical ventilation median time Multivariable regression multivariate logistic regression multivariate model observational study on admission Patient patients hospitalized Primary outcome qSOFA radiological Result retrospective Retrospective study risk factor Risk factors SARS-CoV-2 infected patient SARS-COV-2 infection Seven Symptom symptoms onset university hospital [DOI] 10.1371/journal.pone.0240781 PMC 바로가기 [Article Type] Research Article
SARS-CoV-2 antibody prevalence in health care workers: Preliminary report of a single center study의료 종사자의 SARS-CoV-2 항체 유병률: 단일 센터 연구의 예비 보고서Research Article Published on 2020-11-122022-08-13 Journal: PLoS ONE [Category] Biochemistry, COVID-19, MERS, SARS, [키워드] adaptive addition adjusted age Analysis antibody blood sample Care Cell mediated immunity Cohort collected Community Complete conducted COVID-19 antibody COVID-19 symptoms cross-reactive described Fever General population greater Health healthcare healthcare worker Healthcare workers higher risk hospital household contact household contacts IgG antibodies IgG antibody implementation include increasingly independent individuals Infection Infection transmission initial investigated Local Loss of Smell mediated immunity medical staff Observed orange outcomes patient triage PCR test Personal protective equipment positive Prevalence recruited risk SARS-CoV-2 SARS-CoV-2 antibody Sensitivity and specificity serological survey Serological surveys serum analysis Significant single center subject T cell tested Travel Treatment protocol was collected with COVID-19 [DOI] 10.1371/journal.pone.0240006 PMC 바로가기 [Article Type] Research Article
Repurposing therapeutics for COVID-19: Rapid prediction of commercially available drugs through machine learning and dockingCOVID-19에 대한 용도 변경 치료제: 머신 러닝 및 도킹을 통해 상업적으로 이용 가능한 약물의 신속한 예측Research Article Published on 2020-11-122022-08-13 Journal: PLoS ONE [Category] Biochemistry, COVID-19, MERS, SARS, [키워드] accelerate Accuracy Amprenavir antiretroviral drug approach approved can be used caused clinical recovery clinical trial clinical trials Community coronavirus disease COVID-19 COVID-19 treatment criterion disease docking drug drug design Drug discovery DrugBank drugs effective Epidemic epidemic disease FDA futuristic smart drug designing strategy globe help improvement infected case machine learning market medication ML model mortality rate Naive Bayes algorithm new drug combination new virus Novel coronavirus novel coronavirus disease other disease other diseases outbreak predict protocol protocols Rapid reported repurposing required researcher SARS-CoV-2 SARS-CoV-2 virus selected selective Spread the disease the SARS-CoV-2 virus therapeutic agent therapeutic agents treat Treatment treatment of COVID-19 treatment regimen treatment regimens Vaccines virus [DOI] 10.1371/journal.pone.0241543 PMC 바로가기 [Article Type] Research Article
Thyroid Function Before, During, and After COVID-19코로나19 전, 중, 후 갑상선 기능Observational Study Published on 2020-11-122022-08-13 Journal: The Journal of Clinical Endocrinology and Metaboli [Category] Biochemistry, MERS, 임상, [키워드] Admission Adult patient Adult patients baseline case analysis Cohort college complete case analysis conducted Context COVID-19 COVID-19 patient COVID-19 patients determine disease Effect euthyroid euthyroidism Evidence Follow-up function London measure Mild Most patient Most patients National Health Service nonthyroidal illness syndrome objective observational study participant patients presenting recent reduced reductions in reported Result returned setting suppression suppression of thyroid function survivor Thyroid thyroid disease thyroid function thyroid function test Thyroid function tests thyroid gland thyrotoxicosis thyrotropin thyroxine Trust TSH were recorded with COVID-19 [DOI] 10.1210/clinem/dgaa830 PMC 바로가기 [Article Type] Observational Study
Organizing pneumonia of COVID-19: Time-dependent evolution and outcome in CT findingsCOVID-19의 폐렴 조직화: CT 소견의 시간 의존적 진화 및 결과Research Article Published on 2020-11-112022-08-13 Journal: PLoS ONE [Category] Biochemistry, COVID-19, MERS, SARS, [키워드] Admission adverse outcome analyzed Complete consolidation coronavirus disease COVID-19 COVID-19 patient CT finding CT findings CT scan death discharge discharged distribution evaluated Evolution feature Frequency GGO ground glass opacities Ground glass opacity group groups ICU involved lesion lesions linear lobar lobe material median MOST Novel coronavirus novel coronavirus disease Organizing pneumonia outcome pandemic Patient percentage percentages Pneumonia Prognosis Result severity Significant significant differences time interval time intervals [DOI] 10.1371/journal.pone.0240347 PMC 바로가기 [Article Type] Research Article
Seroprevalence of SARS-CoV-2 specific IgG antibodies in District Srinagar, northern India – A cross-sectional study인도 북부 스리나가르 지구에서 SARS-CoV-2 특이적 IgG 항체의 혈청 유병률 – 단면 연구Research Article Published on 2020-11-112022-08-13 Journal: PLoS ONE [Category] Biochemistry, COVID-19, MERS, SARS, [키워드] 95% CI adjusted age Background Prevalence cross-sectional disease District higher odd higher odds hospital IgG antibodies IgG antibody India Infection Influenza information Measures median Microparticle participated people with symptom proportion provide quarantine Result SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections selected serologic test Seroprevalence significantly specific IgG antibodies specific IgG antibody susceptible Symptom tested the District with COVID-19 [DOI] 10.1371/journal.pone.0239303 PMC 바로가기 [Article Type] Research Article