Adaptive immune response – Page 10 – Communicable Diseases Research

Hyperinflammatory Immune Response and COVID-19: A Double Edged Sword

Immunology

Published on 2021-09-302022-11-01
Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS,

Normal T and B Cell Responses Against SARS-CoV-2 in a Family With a Non-Functional Vitamin D Receptor: A Case Report

Immunology

Published on 2021-09-302022-11-01
Journal: Frontiers in Immunology [Category] COVID-19, SARS,

Natural Polyphenols as Immunomodulators to Rescue Immune Response Homeostasis: Quercetin as a Research Model against Severe COVID-19

면역 반응 항상성을 구조하기 위한 면역 조절제로서의 천연 폴리페놀: 심각한 COVID-19에 대한 연구 모델로서의 케르세틴

Review

Published on 2021-09-252022-09-10
Journal: Molecules [Category] SARS, 치료제,

[키워드] Adaptive immune response Analysis appearance approved asymptomatic infection autophagy broad spectrum caused China Chronic diseases clinical disease clinical trial collected COVID-19 COVID-19 pandemic COVID-19 pathogenesis Cytokines death develop driving dysregulated dysregulated immune response elicited Health Health crisis identify immune responses immunological mechanism immunomodulation immunomodulatory activity Immunomodulatory agent Immunomodulatory agents in vitro in vivo Inflammation Inflammatory response Lymphocytes macrophages mechanism Model natural Pathogenesis polyphenol polyphenols producing quercetin reducing rescue Research response SARS-CoV-2 SARS-COV-2 infection severe COVID-19 severity Spread suggested therapeutic drug treat Vaccines
[DOI] 10.3390/molecules26195803 PMC 바로가기 [Article Type] Review

Pattern Recognition Proteins: First Line of Defense Against Coronaviruses

Immunology

Published on 2021-09-232022-11-01
Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS,

[키워드] acute respiratory distress syndrome adaptive Adaptive immune response Affect affecting Against apoptotic cell ATH - atherosclerosis atherosclerotic lesions C-reactive protein C1q cardiovascular complication cardiovascular system caused clearance combination treatment complement Complication composed coronavirus Coronaviruses COVID- 19 COVID-19 COVID-19 disease death development Direct Effect enhancement global healthcare host’s immune system IgM antibodies immune Immunity Innate innate and adaptive IgM antibodies Innate immunity involved killing LINE lung novel coronavirus SARS-CoV-2 outbreak pandemic patients with SARS-CoV-2 pattern pattern recognition proteins Prevent Prophylactic Protein Recognition recognition protein reduce RNA virus RNA viruses SARS-CoV-2 SARS-CoV-2 virus severe disease severe respiratory syndrome surfactant surfactant proteins A and D (SP-A and SP-D) the SARS-CoV-2 Therapeutic approach therapy Vaccine viral particle virus worldwide pandemic Wuhan, China
[DOI] 10.3389/fimmu.2021.652252 PMC 바로가기 [Article Type] Immunology

Lymphopenia Caused by Virus Infections and the Mechanisms Beyond

Review

Published on 2021-09-202022-10-28
Journal: Viruses [Category] COVID-19,

Association of HLA genotypes, AB0 blood type and chemokine receptor 5 mutant CD195 with the clinical course of COVID-19

HLA 유전자형, AB0 혈액형 및 케모카인 수용체 5 돌연변이 CD195와 COVID-19의 임상 경과와의 연관성

Observational Study

Published on 2021-09-162022-09-10
Journal: European Journal of Medical Research [Category] 변종, 임상, 진단,

[키워드] ABO blood group absence Adaptive immune response addition addressed age Analysis anti-S IgG anti-S IgG levels Antigen antigens antiviral immune response association benefit Blood Blood Group carriers caused CCR5 Chemokine receptor Clinical course clinical courses Cohort Composite courses COVID-19 COVID-19 convalescent patient Cox regression deletion mutant disease disease severity DRB1 exploratory fatal disease Follow-up genetics genotypes Group antigen heterozygous Hierarchical HLA HLA allele HLA alleles HLA class I HLA class I genotypes HLA class II Human human leukocyte antigen humoral immune responses immunogenetic background infection with SARS-CoV-2 investigated leukocyte median Mild Moderate COVID-19 morbidity mutant Mutation Neutralizing antibodies neutralizing capacity observation observational study pandemic disease parameter patient cohort patient population pauci-symptomatic potential risk presence or absence progression prolonged disease Prospective Protective protective effect reduced required Result SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants severe disease severity significantly supplementary material the patient vaccination response virus was performed
[DOI] 10.1186/s40001-021-00560-4 PMC 바로가기 [Article Type] Observational Study

A Combination Adjuvant for the Induction of Potent Antiviral Immune Responses for a Recombinant SARS-CoV-2 Protein Vaccine

재조합 SARS-CoV-2 단백질 백신에 대한 강력한 항바이러스 면역 반응 유도를 위한 조합 보조제

Immunology

Published on 2021-09-162022-09-11
Journal: Frontiers in Immunology [Category] SARS, 변종, 진단,

[키워드] activate Adaptive immune response adaptive immune responses adjuvant adjuvants antibody Antibody titers Antigen B.1.351 breadth candidate cellular response Combination cross-protection effective elicited ENhance Heterologous homologous Immune profile immune responses Immunity IMPROVE induction intranasal intranasal vaccine mice mucosal mucosal adjuvant N501Y mutation nanoemulsion (NE) neutralizing antibody titers NLRP3 P.1 variants passive transfer potent recombinant response RIG-I RIG-I agonist RNA robust SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 variant SARS-CoV-2 variants Spike protein TLR TLRs transfer vaccination variant variants variety Viral viral challenge virus-neutralizing antibody
[DOI] 10.3389/fimmu.2021.729189 PMC 바로가기 [Article Type] Immunology

B Cell Receptor Repertoire Analysis in Malaria-Naive and Malaria-Experienced Individuals Reveals Unique Characteristics of Atypical Memory B Cells

말라리아에 노출되지 않은 개인과 말라리아 경험이 있는 개인의 B 세포 수용체 레퍼토리 분석은 비정형 기억 B 세포의 독특한 특성을 드러냅니다.

Research Article

Published on 2021-09-152024-08-08
Journal: mSphere [Category] 말라리아,

[키워드] Adaptive immune response HCDR3 Humoral immunity IgM Plasmodium Somatic hypermutation
[DOI] 10.1128/mSphere.00726-21 PMC 바로가기 [Article Type] Research Article

Immunopathology and Immunosenescence, the Immunological Key Words of Severe COVID-19. Is There a Role for Stem Cell Transplantation?

Cell and Developmental Biology

Published on 2021-09-142022-10-31
Journal: Frontiers in Cell and Developmental Biology [Category] COVID-19,

Resveratrol as an Adjunctive Therapy for Excessive Oxidative Stress in Aging COVID-19 Patients

Review

Published on 2021-09-092022-10-28
Journal: The Cochrane database of systematic reviews [Category] COVID-19,

[키워드] accelerate accompanied Adaptive immune response Adaptive immunity age aging antioxidant antioxidants antiviral activity antiviral immunity Asymptomatic Comorbidities coronavirus disease COVID-19 COVID-19 symptom Cytokine storm deficiency dendritic cell determinant disease distress dysregulation Elderly patient Healthcare system heterogeneous Illness severity immune function Immunosuppression Infection Inflammation Inflammatory inflammatory immune response inhibiting viral replication Innate immunity interferon Macrophage Mild molecular mechanism outcomes oxidative oxidative stress pandemic pathophysiological progression response resulting resveratrol risk SARS-CoV-2 SARS-COV-2 infection Sex Symptoms the patient Treatment viral infections
[DOI] 10.3390/antiox10091440 PMC 바로가기 [Article Type] Review