Impaired
[용어속성] Term
The role of dysregulated immune responses in COVID-19 pathogenesis
Review
[키워드] acute respiratory distress
Adults
appear
ARDS
caused
children
clinical manifestation
Complication
Consequences
coronavirus
COVID-19
COVID-19 pathogenesis
Critical
difference
disorder
dysregulated immune response
global public health
Host
immune dysregulation
immune regulation
immune response
immune system
immunocompetent cell
Immunopathogenesis
Impaired
IMPROVE
Infant
infections
Inflammation
Local
lung
Mild
pandemic
pathogenesis of COVID-19
recognizing
reduction in
Research
SARS-CoV-2
SARS-COV-2 infection
severe COVID-19 disease
severity of COVID-19
Spread
syndrome
systemic immune response
treatment protocols
virus
[DOI] 10.1016/j.virusres.2020.198197 PMC 바로가기 [Article Type] Review
[DOI] 10.1016/j.virusres.2020.198197 PMC 바로가기 [Article Type] Review
Traditional Herbal Medicine Candidates as Complementary Treatments for COVID-19: A Review of Their Mechanisms, Pros and Cons
Review Article
Published on
Journal: Evidence-based Complementary and Alternative Medicine : eCAM [Category] COVID-19,
Journal: Evidence-based Complementary and Alternative Medicine : eCAM [Category] COVID-19,
[키워드] acute respiratory syndrome
addition
Antiviral
candidate
caused
Cinchona
clinical trial
Compound
conducted
coronavirus
Coronavirus disease 2019
COVID-19
COVID-19 pandemic
COVID-19 patients
Curcuma
drug candidate
Echinacea
effective
evaluate the effect
experiments
Factor
Herbal
immune regulation
immunomodulator
immunomodulators
Impaired
Infectious disease
Medicine
outcome
pandemic
Pathogenesis
plants
Prevent
Pro
recommendation
reported
review
SARS-CoV-2
significantly
the disease
Traditional
Treatment
[DOI] 10.1155/2020/2560645 PMC 바로가기 [Article Type] Review Article
[DOI] 10.1155/2020/2560645 PMC 바로가기 [Article Type] Review Article
Disharmonic Inflammatory Signatures in COVID-19: Augmented Neutrophils’ but Impaired Monocytes’ and Dendritic Cells’ Responsiveness
Article
[키워드] caused
COVID-19
cytokine
cytokine production
Cytokine storm
degranulation
demonstrated
dendritic cell
dendritic cells
disease
driver
feature
forms
functional
Health
highlight
hyperinflammation
IFN alpha
immature
Impaired
innate immune
Innate immunity
Interaction
interferon
involved
low expression
maturation
mechanisms
monocyte
Monocytes
NETosis
neutrophil
Neutrophils
pandemic disease
PD-L1
phenotype
profile
reduce
Research
responses
responsiveness
SARS-CoV-2
SARS-CoV-2 virus
severity of COVID-19
signature
therapeutic targeting
with COVID-19
[DOI] 10.3390/cells9102206 PMC 바로가기 [Article Type] Article
[DOI] 10.3390/cells9102206 PMC 바로가기 [Article Type] Article
Olfactory and gustatory dysfunction in COVID‐19 patients: A meta‐analysis study
Original Research
[키워드] 95% CI
95% confidence interval
Analysis
article
articles
calculated
carried
caused
Clinical course
confidence interval
COVID‐19
COVID‐19 infection
COVID‐19
demonstrated
disorder
dysfunction
early diagnosis
effective
estimated rate
Frequency
global pandemic
Gustatory
Impaired
impairment
independent
information
Joanna Briggs Institute
main outcome measure
Novel coronavirus
olfactory
participant
Patient
positive patients
Prevalence
prevalence rate
provided
random effect model
reported
Result
searched
Smell
study population
Taste
Web of Science
were assessed
were excluded
[DOI] 10.14814/phy2.14578 PMC 바로가기 [Article Type] Original Research
[DOI] 10.14814/phy2.14578 PMC 바로가기 [Article Type] Original Research
Impaired Cytotoxic CD8 + T Cell Response in Elderly COVID-19 Patients
Research Article
[키워드] absence
acute infection
acute respiratory syndrome
age
aging
analyzed
CD4
CD4+
CD8
CD8+
Cell
cells
characterized
contribute
coronavirus
COVID-19
COVID-19 patient
COVID-19 patients
cytotoxic
Cytotoxic T cell
Cytotoxic T cells
disease course
effector memory
elderly
Elderly patient
Express
granzyme
immunopathology
Impaired
Impaired Cellular Immunity
implication
induce
infected cell
Infection
information
killing
Mild
PD-1
perforin
phenotype
produced
response
responsible
SARS-CoV-2
SARS-COV-2 infection
severity of COVID-19
T cell
T cell response
T cells
terminally differentiated
Vaccine development
virus
viruses
younger patients
[DOI] 10.1128/mBio.02243-20 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1128/mBio.02243-20 PMC 바로가기 [Article Type] Research Article
Impaired immune and coagulation systems may be early risk factors for COVID-19 patients A retrospective study of 118 inpatients from Wuhan, China
3900
[키워드] 95% CI
95% confidence interval
Admission
AUC
characteristic
clinician
Coagulation system
collected
coronavirus disease
Coronavirus disease 2019
COVID-19
COVID-19 outbreak
COVID-19 patient
COVID-19 patients
d -dimer
demographics
diagnosed with COVID-19
Diagnosis
District
early diagnosis
Efficiency
enrolled
Factor
females
greater
Health
Hospital mortality
immune
Impaired
IMPROVE
In-hospital
in-hospital mortality
Inpatient
laboratory data
Logistic regression
Lymphocyte count
lymphocytopenia
male
mortality risk
multivariable logistic regression
neutrophil count
nonsurvivors
Odds ratio
Older age
outbreak
Patient
patients with COVID-19
PCT
procalcitonin
Prothrombin time
Renmin Hospital
Retrospective study
risk factor
ROC
ROC Curve
survivor
Treatment
univariable
university
Wuhan
Wuhan, China
[DOI] 10.1097/MD.0000000000021700 PMC 바로가기 [Article Type] 3900
[DOI] 10.1097/MD.0000000000021700 PMC 바로가기 [Article Type] 3900
Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients
Report
[키워드] Analysis
Antiviral
antiviral immunity
bacterial superinfections
Blood
cause
characterized
Cohort
coronavirus disease
Coronavirus disease 2019
COVID-19
COVID-19 patient
Critical
critical COVID-19 patient
deficiency
dendritic cell
Disease progression
disease severity
driven by
driving
elicit
engage
ENhance
epithelial
exacerbated
expressed
expression
functions
hallmark
host immune responses
IFN
IFN signaling
IFN-stimulated gene
IFN-α
IFN-β
IFN-λ
IFNs
immune
Immune cell
immunopathology
Impaired
increase
Inflammatory response
influenza infection
inhibiting
interfere
interferon
interleukin-6
ISGs
Local
lung
lung epithelium
Major
mice
morbidity
mucosal surface
Necrosis
nuclear
p53
parameter
patients
performed
Peripheral blood
phenotype
proinflammatory
proliferation
respiratory viral infections
response
responses
Science
secreted
severe COVID-19
severe COVID-19 patient
severity
Signaling
susceptibility
therapeutic
therapeutic approaches
thought
Transcription
transcriptional
Trigger
turn
Type
type I
Type I IFN
type I interferon
Type III IFN
viral infections
Viral load
viral respiratory disease
viral respiratory infections
Viral RNA
[DOI] 10.1126/science.abc6027 PMC 바로가기 [Article Type] Report
[DOI] 10.1126/science.abc6027 PMC 바로가기 [Article Type] Report
Impaired Fasting Glucose and Diabetes Are Related to Higher Risks of Complications and Mortality Among Patients With Coronavirus Disease 2019
Endocrinology
[키워드] 95% confidence interval
Admission
adverse outcome
age
Analysis
analyzed
association
clinical
cohort study
collected
Comorbidities
Complication
complications
coronavirus
COVID-19
Cox proportional hazard
Cox regression
death
diabete
diabetes
enrolled
evaluated
event
fasting
fasting glucose
hazard ratio
higher risk
hospital
Hospital admission
hospitalized patient
hyperglycemia
Impaired
impaired fasting glucose
increased risk
information
intensive care
interquartile range
Laboratory
mechanical ventilation
median age
Mortality
multicenter
outcome
Patient
patients with COVID-19
poor prognosis
receiving
regression models
retrospective cohort study
risk
risk factor
severe acute respiratory coronavirus 2 (SARS-CoV-2)
Sex
the patient
treatment regimens
with COVID-19
women
Wuhan
[DOI] 10.3389/fendo.2020.00525 PMC 바로가기 [Article Type] Endocrinology
[DOI] 10.3389/fendo.2020.00525 PMC 바로가기 [Article Type] Endocrinology
Role of Autophagy in Lung Inflammation
Immunology
[키워드] accompanied
activated
antigen presenting cell
approach
Asthma
asthmatic
autophagic
autophagic flux
autophagy
caused
Cell
cell type
cells
cellular
cellular homeostasis
changes in
characterized
complicate
COVID-19
decrease
develop
disease
dysfunction
Effects
eukaryotic
functions
granulocyte
human cell
Immune cell
immunometabolism
Impaired
implicated
implication
Inflammasome
Inflammation
inflammatory disease
Lineage
lung
Lung inflammation
lymphoid
lymphoid cell
lysosome
metabolism
modulation
myeloid cells
non-immune
Organisms
Pathogenesis
pathology
phenotype
Population
populations
Protein
role
SARS-CoV-2
shown
specificity
survival
Symptoms
tissue remodeling
Treatment
variety
viral pathogenesis
worse prognosis
[DOI] 10.3389/fimmu.2020.01337 PMC 바로가기 [Article Type] Immunology
[DOI] 10.3389/fimmu.2020.01337 PMC 바로가기 [Article Type] Immunology