Coronavirus-19 disease (COVID-19): A case series of early suspected cases reported and the implications towards the response to the pandemic in ZimbabweShort communication Published on 2020-06-012022-10-05 Journal: Journal of microbiology, immunology, and infection [Category] SARS, 진단, [키워드] Africa case sery conducted consequence coronavirus country COVID-19 COVID-19 pandemic COVID-19 test diagnostic test disease Emergency preparedness and response ENhance Health care worker implication management Mental offered official pandemic Psychological reported resource risk screening process Surveillance training virus were used Zimbabwe [DOI] 10.1016/j.jmii.2020.04.002 [Article Type] Short communication
Severe Acute Respiratory Syndrome Coronavirus 2 from Patient with Coronavirus Disease, United StatesExpedited Published on 2020-06-012022-10-31 Journal: Emerging Infectious Diseases [Category] COVID-19, SARS, [키워드] 2019 novel coronavirus disease absence acute respiratory syndrome Cell culture center characterization characterized Control coronavirus coronavirus 2 COVID-19 Diagnosis Infection Isolation Medical countermeasures nasopharyngeal oropharyngeal specimen outbreak Patient PCR Pneumonia prevention public health replicate Replication Research respiratory respiratory infections SARS-CoV-2 sequence severe acute respiratory syndrome coronavirus 2 the United State trypsin United State United States Vero E6 cell Vero-CCL81 cell virus viruses Washington Wuhan, China zoonoses [DOI] 10.3201/eid2606.200516 PMC 바로가기 [Article Type] Expedited
Telemedicine in the face of the COVID-19 pandemicArticle Published on 2020-06-012023-07-14 Journal: Atencion Primaria [Category] SARS, [키워드] Brote coronavirus COVID-19 Infecciones infections outbreak Telemedicina Telemedicine virus viruses [DOI] 10.1016/j.aprim.2020.04.003 PMC 바로가기
Perspectives for the use of therapeutic Botulinum toxin as a multifaceted candidate drug to attenuate COVID-19Review article Published on 2020-06-012022-10-05 Journal: Medicine in Drug Discovery [Category] 신약개발, [키워드] ACE2 acute respiratory syndrome appear attenuate Botox Botulinum toxin Brain circulation clinical symptom Clinical symptoms coronavirus coronavirus disease Coronavirus-2 cough country COVID-19 death dose Dyspnoea functional global public health humans individuals with COVID-19 induce Infection life-threatening lung Lungs Mild multi-organ dysfunction neurodegeneration Neurological deficit neurological deficits other organ outbreak paralysis Pneumonia Prevent provide pulmonary failure purified Respiratory failure resulting SARS-CoV-2 SARS-COV-2 infection the SARS-CoV-2 therapeutic therapeutic use virus while [DOI] 10.1016/j.medidd.2020.100042 [Article Type] Review article
A Snapshot of SARS-CoV-2 Genome Availability up to April 2020 and its Implications: Data AnalysisOriginal Paper Published on 2020-06-012022-10-31 Journal: JMIR Public Health and Surveillance [Category] COVID-19, SARS, [키워드] acute respiratory syndrome affecting Analysis available data coronavirus COVID-19 data set determine dissemination distress effort Evolution genetic heterogeneity genetics Genome genome sequence GISAID Infectious disease information initiative limitation limitations objective pandemic Phylogenetic phylogenetics plethora released required Result robust SARS-CoV-2 SARS-CoV-2 sequence Scientific community sequence spatiotemporal Spread the epidemic tracing tracking Transmission transmission cluster viral sequence virus [DOI] 10.2196/19170 PMC 바로가기 [Article Type] Original Paper
In Vitro Evaluation of Curcumin-Encapsulated Chitosan Nanoparticles against Feline Infectious Peritonitis Virus and Pharmacokinetics Study in CatsResearch Article Published on 2020-05-312022-10-27 Journal: BioMed Research International [Category] Coronavirus, MERS, [키워드] antiviral activity Antiviral effect average bead-based multiplex immunoassay Bioavailability biological activity C max Cell chitosan Crandell-Rees feline kidney cuboidal Curcumin decrement Effect Evidence expression Feline infectious peritonitis high mortality rate HPLC IL-1 β IL-6 immune-related protein immunoassay IMPROVE Infection Inflammatory response lower toxicity Multiple-dose multiplex nanoparticle Necrosis notable oral oral bioavailability peritonitis pharmacokinetics plasma concentration profile proinflammatory cytokines provide qPCR selective synthesised therapeutic TNF TNF α Treatment viral disease virus were used [DOI] 10.1155/2020/3012198 PMC 바로가기 [Article Type] Research Article
Towards the design of epitope candidates for Coronavirus 2Research-Article Published on 2020-05-312022-10-28 Journal: Bioinformation [Category] COVID-19, [키워드] 2019 novel coronavirus 2019-nCoV acute respiratory distress acute respiratory syndrome alveolar cell antigenicity B-cell B-cell epitope beta coronavirus candidate Care cell entry receptor Comorbidities coronavirus 2 Coronavirus-2 COVID-19 develop disease Elderly patient enzyme epitope infect linear lung pandemic peptide Pneumonia predicted Proteases public health threat SARS-CoV-2 screened selected sequence spike glycoprotein stability syndrome T-cell epitope the spike protein therapy Treatment Vaccine vaccine candidate virus [DOI] 10.6026/97320630016375 PMC 바로가기 [Article Type] Research-Article
Development of a Portable, Ultra-Rapid and Ultra-Sensitive Cell-Based Biosensor for the Direct Detection of the SARS-CoV-2 S1 Spike Protein AntigenLetter Published on 2020-05-312022-10-29 Journal: Sensors (Basel, Switzerland) [Category] COVID-19, MERS, SARS, [키워드] addition antibody Antigen applied Asymptomatic Bioelectric Recognition Assay (BERA) biosensor cellular chimeric coronavirus COVID-19 pandemic cross-reactivity detect detection Detection limit development Direct expressed individuals mammalian cell membrane engineering membrane-bound nucleocapsid protein number of infected pandemic patients platform Point-of-Care (POC) Protein provided Recognition S1 spike protein SARS-CoV-2 selective Serological assay severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) spike Spike protein the SARS-CoV-2 virus [DOI] 10.3390/s20113121 PMC 바로가기 [Article Type] Letter
Why does COVID-19 disproportionately affect older people?Review Published on 2020-05-312022-10-28 Journal: Aging (Albany NY) [Category] COVID-19, MERS, SARS, [키워드] acute respiratory distress Affect age aging cardiovascular disease Coagulopathy consolidation coronavirus disease cough COVID-19 COVID-19 patient Cytokine release syndrome Cytokine storm death diabete Dyspnea Endotheliitis epigenetic clock explain fatal disease Fever genetic test greater Hospitalization identify immune responses Immunity independent risk factor individual Infection inhibiting life-threatening lung mechanism mechanisms mild illness molecular multiple organ failure obesity Older outcome regulate risk risk of death severity survival syndrome the disease Treatment virus [DOI] 10.18632/aging.103344 PMC 바로가기 [Article Type] Review
Porcine Epidemic Diarrhea Virus nsp15 Antagonizes Interferon Signaling by RNA Degradation of TBK1 and IRF3Article Published on 2020-05-312022-10-28 Journal: Viruses [Category] Coronavirus, MERS, [키워드] acute respiratory syndrome Amino acid Analysis antagonistic antiviral response cause Cell component coronavirus correlated Critical degrade dependent on disease downregulated endoribonuclease epidemic diarrhea facilitate Host IFN IFN response IFN signaling pathway IFN-I Infection inhibit innate immune innate response interferon regulatory factor interferon signaling involved IRF3 ISGs Nsp15 other coronaviruses pathogenic mechanism pathway PEDV Protein reduction Replication residue RNA RNA degradation SARS-CoV screened stimulated suppress TBK1 type I interferon virus virus infection [DOI] 10.3390/v12060599 PMC 바로가기 [Article Type] Article