Misalignment between coronavirus financial aid and public health policies: negative incentives for outpatient clinics in the United StatesViewpoint Published on 2020-09-252022-10-30 Journal: Journal of public health policy [Category] Coronavirus, SARS, [키워드] Act AID Clinical practice clinics coronavirus COVID-19 COVID-19 infection downstream Effect employment evaluated implication increased risk maintain Measures patients Policy Program protection public health relief SARS-CoV2 security Telemedicine the United State United State [DOI] 10.1057/s41271-020-00256-9 PMC 바로가기 [Article Type] Viewpoint
The Coronaviruses of Animals and Birds: Their Zoonosis, Vaccines, and Models for SARS-CoV and SARS-CoV2Veterinary Science Published on 2020-09-242022-11-01 Journal: Frontiers in Veterinary Science [Category] COVID-19, [키워드] accumulated addition addressed animal animal model BCoV bovine canine carried contribute coronavirus Coronaviruses determinant Diseases effective vaccine effort Factor family Coronaviridae FCoV human coronavirus implementation mammal MERS-CoV Model mutations New coronavirus Pathogenesis proceed quasispecy raising RNA viruses SARS-CoV SARS-CoV-2 SARS-CoV2 Treatment Trial Vaccine Vaccine development Vaccines virus zoonosis zoonotic disease [DOI] 10.3389/fvets.2020.582287 PMC 바로가기 [Article Type] Veterinary Science
The Possible Dual Role of the ACE2 Receptor in Asthma and Coronavirus (SARS-CoV2) InfectionCellular and Infection Microbiology Published on 2020-09-232022-10-31 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID-19, MERS, SARS, [키워드] ACE2 Asthma COVID 19 Inflammation role SARS-CoV2 [DOI] 10.3389/fcimb.2020.550571 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
Retrospective Analysis of a Modified Organizational Model to Guarantee CT Workflow during the COVID-19 Outbreak in the Tertiary Hospital of Padova, ItalyArticle Published on 2020-09-212022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] acute respiratory syndrome approach average Care Cluster Computed tomography coronavirus COVID-19 COVID-19 patient Department diagnostic Diagnostic imaging evaluated examined Health healthcare HRCT ICU In-hospital intensive care unit Italy maintain Model Non-COVID-19 patients occurred organizational model outbreak pathway Patient per day performed positive patient positive patients preparedness radiology Resolution Safe SARS-CoV2 Surgical Procedure Tertiary Transmission university [DOI] 10.3390/jcm9093042 PMC 바로가기 [Article Type] Article
Heterogeneous expression of the SARS-Coronavirus-2 receptor ACE2 in the human respiratory tractResearch Paper Published on 2020-09-212022-11-01 Journal: EBioMedicine [Category] COVID-19, MERS, SARS, [키워드] ACE2 ACE2 mRNA ACE2 protein Alveolar Type II alveolar type II cells apical surface association caused Cell children ciliated cells cofactor coronavirus correlation COVID-19 COVID-19 pandemic determine disease disease severity evaluated examined expression Factor Factors finding highest Host human respiratory tract immunohistochemistry incidence interactions Lower respiratory tract lung lung parenchyma material mRNA abundance Numerous offer outbreak protein levels question raise receptor receptor ACE2 reduced Region responsible risk factor SARS-CoV-2 SARS-CoV-2 susceptibility SARS-CoV2 severe COVID-19 severe disease Single-cell RNA sequencing subset susceptibility tissue TMPRSS2 Transmission transmitted Viral transmission [DOI] 10.1016/j.ebiom.2020.102976 PMC 바로가기 [Article Type] Research Paper
Cardiac inflammation in COVID-19: Lessons from heart failureReview Article Published on 2020-09-212023-07-02 Journal: Life sciences [Category] SARS, [키워드] ACE, angiotensin-converting enzyme ARDS, acute respiratory distress syndrome COVID-19 CRP, C-reactive protein CRS, Cytokine release syndrome CVD, cardiovascular disease Cytokine storm heart failure hs-TnI, high sensitivity cardiac troponin I immunopathology macrophages MERS-CoV, Middle East Respiratory Syndrome associated coronavirus Monocytes myocarditis Myofibroblasts Neutrophils NT-proBNP, N-terminal pro-B-type natriuretic peptide SARS-CoV-2, Severe Acute Respiratory Syndrome associated coronavirus SARS-CoV2 TMPRSS2, Transmembrane Protease Serine 2 [DOI] 10.1016/j.lfs.2020.118482 PMC 바로가기 [Article Type] Review Article
Strategies for Targeting SARS CoV-2: Small Molecule Inhibitors—The Current StatusImmunology Published on 2020-09-182022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] ACE-2 ACE2 acute respiratory syndrome ADE aggravate angiotensin Antibody-dependent enhancement Antiviral binding clinical manifestation combating Complication coronavirus strains country COVID-19 current death disease economic loss effective Efficacy exhibit feature genomic Health high mortality human cell immunopathology imperative include infected cases infection with SARS-CoV-2 infections Inflammation inhibitor interfere Lung injury mitigate molecular target molecule more difficult natural antiviral natural Nrf-2 modulators NSMIs oxidative stress patients pharmacological agent Pneumonia positive Protein reported respiratory S-protein SARS-CoV SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 strain SARS-CoV2 small molecule inhibitor spike status Strategy targeting the SARS-CoV-2 Vaccine viral entry viral propagation [DOI] 10.3389/fimmu.2020.552925 PMC 바로가기 [Article Type] Immunology
Immunopathogenesis of COVID-19: Summary and Possible InterventionsImmunology Published on 2020-09-172022-11-01 Journal: Frontiers in Immunology [Category] Coronavirus, MERS, SARS, [키워드] COVID-19 COVID-19 infection COVID-19 pandemic current died effective hyperinflammation Hyperinflammatory immune response immunology Immunosuppression Intervention knowledge Laboratory manifestation mechanism MERS Middle East respiratory SARS-CoV2 therapeutic intervention therapeutic interventions viral escape virus [DOI] 10.3389/fimmu.2020.564925 PMC 바로가기 [Article Type] Immunology
Statin Use Is Associated with Decreased Risk of Invasive Mechanical Ventilation in COVID-19 Patients: A Preliminary StudyArticle Published on 2020-09-172022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] adjusted Admission Affect age Analysis analyzed Anti-inflammatory association associations cardiovascular disease chronic pulmonary disease Comorbidity conducted confidence Course COVID-19 COVID-19 patient CVD Decreased demographics diabetes HMG-CoA HMG-CoA reductase inhibitors hospital Hospitalization hospitalized patients ICU immunomodulatory effects implication IMV In-hospital death inhibitor intensive care interval Invasive mechanical ventilation management Mechanical medication medications multivariate logistic regression obesity outcome past medical history Patient patients hospitalized performed pleiotropic Prospective Study Ratio retrospective cohort study Rhode Island risk SARS-CoV2 severe COVID-19 Sex significantly statin statins Support USA were recorded with COVID-19 [DOI] 10.3390/pathogens9090759 PMC 바로가기 [Article Type] Article
Clinical impact of COVID-19 in a single-center cohort of a prospective study in cancer patients receiving immunotherapyPreliminary Communication Published on 2020-09-162022-10-31 Journal: Immunotherapy [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome Anti-PD-1 cancer patient Cancer patients cardiovascular disease clinical Cohort coronavirus Course COVID-19 diagnosis of COVID-19 eight enrolled Evaluating event feature high risk Immune checkpoint inhibitors Immunotherapy incidence Infection Influenza influenza vaccine interstitial pneumonia males multicenter Patient patients patients died Pharyngeal swab positive Prospective Study receiving reported Respiratory failure SARS-CoV-2 SARS-CoV2 single-center the patient treated [DOI] 10.2217/imt-2020-0211 PMC 바로가기 [Article Type] Preliminary Communication