Seroprevalence Surveys for Anti-SARS-CoV-2 Antibody in Different Populations in Taiwan With Low Incidence of COVID-19 in 2020 and Severe Outbreaks of SARS in 20032020년 COVID-19 발병률이 낮고 2003년 SARS 발병이 심한 대만의 다양한 인구에서 Anti-SARS-CoV-2 항체에 대한 혈청 유병률 조사Immunology Published on 2021-05-182022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, 치료제, [키워드] Abbott Abbott SARS-CoV-2 IgG acute respiratory syndrome anti-SARS-CoV-2 anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody chemiluminescent immunoassay community transmission conducted country COVID-19 COVID-19 vaccine cross-reactivity cross-sectional determined by effective Elecsy Epidemic epidemiological exclusion False-positive frontline healthcare worker group healthy IgG antibodies IgG antibody immunoassay imperative Infection lateral flow immunoassay LINE outbreak pandemic participant Participants Population positive result Prevalence provide qRT-PCR respiratory risk Roche SARS SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 IgG SARS-CoV-2 seroprevalence sera Seroprevalence Severe acute respiratory syndrome Spread survey symptomatic patient Taiwan tested [DOI] 10.3389/fimmu.2021.626609 PMC 바로가기 [Article Type] Immunology
SARS-CoV-2 antibody immunoassays in serial samples reveal earlier seroconversion in acutely ill COVID-19 patients developing ARDS일련의 샘플에서 SARS-CoV-2 항체 면역 분석 결과 ARDS가 발병하는 급성 COVID-19 환자에서 조기 혈청 전환이 나타남Research Article Published on 2021-05-132022-09-12 Journal: PLoS ONE [Category] SARS, 진단, [키워드] acute respiratory distress acute respiratory distress syndrome anti-SARS-CoV-2 Antibody testing ARDS ARDS patient ARDS patients clinical evaluation Cohort cohorts conducted COVID-19 pandemic COVID-19 patient determine diagnostics Disease prevalence Elecsy Elecsys ELISA Germany healthy subject IgA IgG immunoassay individual Lubeck marker objective occurred Patient patients PCR-negative Population potential risk Rate respiratory distress Respiratory distress syndrome Result risk marker Roche Diagnostics SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 antibody testing sensitivities Seroconversion serum side significantly higher Specificities specificity specimen stratified suggested Switzerland syndrome tested therapeutic utility were measured were used [DOI] 10.1371/journal.pone.0251587 PMC 바로가기 [Article Type] Research Article
Vaccination strategy and anti – SARS-CoV-2 S titers in healthcare workers of the INT – IRCCS “Fondazione Pascale” Cancer Center (Naples, Italy)Research Article Published on 2021-05-122022-10-30 Journal: Infectious Agents and Cancer [Category] COVID-19, [키워드] administration age anti-RBD anti-SARS-CoV-2 vaccination anti-spike serology Antibody Response Antibody titer Beads-based linear serology calculated Cancer institute center change Cohort contract the virus coronavirus 2 coronavirus disease COVID-19 disease domain dose Efficacy Elecsy evaluated FDA first dose fold Fold change geometric mean titer glycoprotein healthcare worker humoral immune response immune response immunoassay individual Infection INT IRCCS Italy limit mRNA vaccine naïve subjects Naples Older Post-COVID-19 single dose vaccine. pre-vaccination respiratory Result resulting Roche SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike SARS-CoV-2-infected individual second dose serum sample shown significantly higher spread to statistically significant subject subjects susceptibility the SARS-CoV-2 trimeric spike Vaccine vaccine administration vaccine doses vaccinees [DOI] 10.1186/s13027-021-00375-2 PMC 바로가기 [Article Type] Research Article
Anti-SARS-CoV-2 Receptor-Binding Domain Total Antibodies Response in Seropositive and Seronegative Healthcare Workers Undergoing COVID-19 mRNA BNT162b2 VaccinationArticle Published on 2021-05-042022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] acute respiratory syndrome age age and sex Analysis anti-SARS-CoV-2 anti-SARS-CoV-2 antibody antibodies antibody baseline coronavirus COVID-19 COVID-19 mRNA BNT162b2 COVID-19 vaccination COVID-19 vaccine dependent on domain dose Elecsy Final healthcare worker Humoral response immune response individual Italy magnitude Male sex mRNA patients Pfizer predicted RBD recipients response Roche Roche Diagnostics SARS-CoV-2 seronegative seropositive seropositive subjects Significant significantly study population subject subjects Total total antibodies vaccination Vaccine vaccine dose venous blood Verona women worker [DOI] 10.3390/diagnostics11050832 PMC 바로가기 [Article Type] Article
Target specific serologic analysis of COVID-19 convalescent plasmaCOVID-19 회복기 혈장의 표적 특이적 혈청학적 분석Research Article Published on 2021-04-282022-09-12 Journal: PLoS ONE [Category] MERS, SARS, 진단, [키워드] access anti-RBD assays Beckman Coulter Characteristics clinical clinical sample clinical sensitivity collected convalescent plasma coronavirus disease Coronavirus disease 2019 correlation COVID-19 COVID-19 disease diagnosed with COVID-19 DiaSorin disease disease symptom disease symptoms Donor donors Elecsy Emergency False negative false negative result false negative results FDA IgG investigated LIAISON no difference Panel PCR plasma Roche Roche Diagnostics S1/S2 Sample SARS-CoV-2 SARS-CoV-2 IgG sensitivity serologic analysis serology serology assay specificity statistically significant difference target tested [DOI] 10.1371/journal.pone.0249938 PMC 바로가기 [Article Type] Research Article
Nationwide seroprevalence of antibodies to SARS-CoV-2 in asymptomatic population in South Korea: a cross-sectional study한국의 무증상 인구에서 SARS-CoV-2에 대한 전국적인 혈청 유병률: 횡단면 연구Article Published on 2021-04-242022-09-12 Journal: BMJ Open [Category] MERS, SARS, 진단, [키워드] age analysed anti-SARS-CoV-2 antibody Asymptomatic Characteristics clinical status country COVID-19 COVID-19 outbreak cross-sectional diabetes Elecsy Elecsys electrochemiluminescence immunoassay Epidemiology Fisher Germany Health hypertension Immunity immunologically Infection infection control Korean Logistic regression analysis men MOST obesity performed populations Randomly Region residual respiratory medicine (see thoracic medicine) risk Roche SARS-CoV-2 SARS-CoV-2 antibody secondary outcome selected serological test seropositive serum sample Sex significantly smoking South South Korea subject Thoracic was used were measured women [DOI] 10.1136/bmjopen-2021-049837 PMC 바로가기 [Article Type] Article
Evaluation of a New Spike (S)-Protein-Based Commercial Immunoassay for the Detection of Anti-SARS-CoV-2 IgGArticle Published on 2021-03-312022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] Abbott SARS-CoV-2 IgG analyzed anti-SARS-CoV-2 anti-SARS-CoV-2 S1 IgG antibody assays binding convalescent convalescent patient coronavirus correlated COVID-19 COVID-19 pandemic detection diagnostic DiaSorin Elecsy ELISA evaluated highest Humoral response IgG immunoassay investigated LIAISON Live virus negative control neutralization neutralization tests New non-responder nucleocapsid pandemic protection Proteins pseudovirus representing Roche S1 IgG S1/S2 Sample SARS-CoV-2 sensitivity Sensitivity and specificity Serological assay serum sample spike subject tested the antibody response titer [DOI] 10.3390/microorganisms9040733 PMC 바로가기 [Article Type] Article
Quantitative Measurement of Anti-SARS-CoV-2 Antibodies: Analytical and Clinical EvaluationAnti-SARS-CoV-2 항체의 정량적 측정: 분석 및 임상 평가Article Published on 2021-03-192022-09-11 Journal: Journal of Clinical Microbiology [Category] SARS, 진단, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analytical sensitivity analyzed Anti-SARS-CoV-2 S antibody Antibody Response Antibody testing Antibody titer causative agent claimed clinical clinical evaluation clinical sensitivity coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cross-reactivity detect determine diagnose Elecsy evaluated exhibited facilitate help highest immunoassays Infection Infectious disease interindividual variation limit linearity measure measurement Negative predictive value NPV Patient PCR positivity PCR-positive patient Positive predictive value PPV Predictive value Quality control quantitation Quantitative respiratory Roche Roche Diagnostics S protein SARS-CoV-2 sensitivity serologic assay serologic testing serology severe acute respiratory syndrome Coronavirus specificity specimen target the antibody response the S protein U/mL Vaccines Variation Virology while [DOI] 10.1128/JCM.03149-20 PMC 바로가기 [Article Type] Article
Comparison of the clinical performance and usefulness of five SARS-CoV-2 antibody tests5가지 SARS-CoV-2 항체 검사의 임상 성능 및 유용성 비교Comparative Study Published on 2021-02-082022-09-10 Journal: PLoS ONE [Category] MERS, 진단, 치료기술, [키워드] both groups comparable COVID-19 antibody COVID-19 patients cut-off Elecsy Elecsys epidemiological studies examined FIVE group immunochromatography in both groups Infection Interpretation Japanese Roche SARS-CoV-2 antibody SARS-CoV-2 antibody test serum sample serum samples severe cases severity specificity two group two groups [DOI] 10.1371/journal.pone.0246536 PMC 바로가기 [Article Type] Comparative Study
SARS Coronavirus-2 Microneutralisation and Commercial Serological Assays Correlated Closely for Some but Not All Enzyme ImmunoassaysSARS 코로나바이러스-2 미세중화 및 상업적 혈청학적 분석은 일부 효소 면역분석에 대해 밀접한 상관관계가 있지만 전부는 아님Article Published on 2021-02-042022-09-01 Journal: Viruses [Category] MERS, 진단, 치료기술, 치료제, [키워드] anti-SARS-CoV-2 antibody Antigen antigens best binding antibodies binding antibody collected convalescent plasma correlated correlation COVID-19 COVID-19 pandemic cut-off detect determinant diagnostic Donor donors Elecsy enzyme enzyme immunoassays Euroimmun expressed FIVE greater Host immune response house IgA IgG immunoassay incidence Infection information laboratory-confirmed SARS-CoV-2 infection marker microneutralisation assay negative control Neutralising Antibodies neutralising antibody neutralising antibody titre neutralising antibody titres performance Post-infection Prevalence protective immunity provide Quantitative recovered patient recovered patients reported Research SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-specific antibodies SARS-CoV-2-specific antibody Sensitivity and specificity sera Serological testing serology Spike protein targets vaccination were assessed [DOI] 10.3390/v13020247 PMC 바로가기 [Article Type] Article