endothelial – Page 11 – Communicable Diseases Research

SARS-CoV-2 infection negatively affects ovarian function in ART patients

SARS-CoV-2 감염은 ART 환자의 난소 기능에 부정적인 영향을 미칩니다

Article

Published on 2022-01-012022-09-11
Journal: Biochimica et biophysica acta. Molecular basis of [Category] MERS, SARS, 바이오마커, 진단,

Pilot Study on the Impact of a Home-Based Exercise Program on Inflammatory Cytokines and Quality of Life in Men with Prostate Cancer Under Active Surveillance

Article

Published on 2022-01-012022-11-15
Journal: Cancer control : journal of the Moffitt Cancer Cen [Category] 바이오마커,

[키워드] 6-minute walk test 6MWT 6MWT distance Active surveillance aerobic Alpha baseline Biomarker Biomarkers body mass index collected control group COVID-19 decrease emotional endothelial exercise Exercise intervention functional Future growth factor IL-12 IL-1α IL-5 IL-6 Impact increase in INF-γ Inflammatory biomarker Inflammatory cytokine interferon-γ interleukin-6 Intervention intervention group Isolation life marker men Necrosis parallel group physical Program Prostate Prostate cancer Quality Quality of life Randomized Significant significantly increased TNF-α translation tumor progression Vascular VEGF was used
[DOI] 10.1177/10732748221130964 PMC 바로가기

Drugs Used in the Treatment of Multiple Sclerosis During COVID-19 Pandemic: A Critical Viewpoint

Covid-19 Pandemic 동안 다발성 경화증 치료에 사용되는 약물 : 중요한 관점

Article

Published on 2022-01-012022-08-31
Journal: Current neuropharmacology [Category] SARS, 치료제,

[키워드] Acetate activating acute respiratory distress acute respiratory distress syndrome Alemtuzumab analogue antiviral activity approved ARDS autoimmune disorder Autoimmune disorders caution cellular Cladribine concern COVID-19 COVID-19 infection COVID-19 pandemic cytokine Cytokine storm Defense depleting detrimental dimethyl fumarate disease Disease-modifying therapy drug early stage endothelial example fingolimod fumarate Glatiramer Glatiramer acetate health problem hyperinflammation Hyperinflammatory IFN IFNs immunomodulation interfere interferon Invasion lung Macrophage mechanisms Multiple multiple sclerosis Natalizumab neuroprotection Nrf-2 nucleotide nucleotides Ocrelizumab other organs overcome oxidative stress pathway potential risk Protective public health raised reinforcement respiratory distress risk risk-benefit ratio. Safe SARS-CoV-2 SARS-COV-2 infection sclerosis suggested syndrome Teriflunomide Treatment Viral viral replication
[DOI] 10.2174/1570159X19666210330094017 PMC 바로가기 [Article Type] Article

BPC 157 as Potential Treatment for COVID-19

Research article

Published on 2022-01-012022-10-05
Journal: Medical Hypotheses [Category] 임상, 치료법,

[키워드] activated acute respiratory distress animal model Anti-inflammatory BPC 157 cardiovascular complications caused China Clinical management clinical trial Clinical use Comorbidity complementary Complication coronavirus disease Course COVID-19 COVID-19 patient Critical Cytoprotection demonstrated Effect effective endothelial Endothelial cell Endothelial cells (ECs) Endothelial nitric oxide synthase (eNOS) examined explain functions Human immune response IMPROVE Liver damage multi-organ failure neurological nitric oxide organ injury organ system outbreak patients peptide Potential proinflammatory Prophylactic provoke reduced syndrome the disease thrombotic tissue repair Treatment Vascular vascular disease
[DOI] 10.1016/j.mehy.2021.110736 [Article Type] Research article

Distinctive Biomarker Features in the Endotheliopathy of COVID-19 and Septic Syndromes

COVID-19 및 패혈성 증후군의 내피병증에서의 독특한 바이오마커 특징

Comparative Study

Published on 2022-01-012022-09-11
Journal: Shock (Augusta, Ga.) [Category] 바이오마커,

[키워드] Activation ADAMTS adhesion analyzed Biomarker Biomarkers both groups circulating clinical disease collected complement Complement activation contributing to Control COVID-19 COVID-19 disease COVID-19 disease severity COVID-19 group COVID-19 patient COVID-19 patients COVID-19 phenotype COVID-19 pneumonia Critical critical COVID-19 patient critical COVID-19 patients Critically ill critically ill COVID-19 patients Culture disease disease severity dsDNA dysregulation e parameters endothelial Endothelial cell endothelial cells endothelial damage endotheliopathy except for Factor fibrinolysis fibrinolytic healthy donor healthy donors help heparan sulfate Hospitalization ICU in both groups increased expression information intensive care life-threatening mitigate moderate morbidity and mortality motif NETs neutrophil Neutrophil extracellular trap Neutrophil extracellular traps parameter pathophysiology Patient Phenotypes plasma samples Pneumonia progression receptor Result Sepsis sepsis syndrome septic Septic shock severity of COVID-19 significantly significantly higher significantly lower SIRS Stage Stress sulfate syndrome systemic inflammatory response systemic inflammatory response syndrome therapeutic strategy thrombomodulin TNF volunteers von Willebrand factor vWF was related with COVID-19
[DOI] 10.1097/SHK.0000000000001823 PMC 바로가기 [Article Type] Comparative Study

Exploring potential mechanisms of Suhexiang Pill against COVID-19 based on network pharmacology and molecular docking

네트워크 약리학 및 분자 도킹을 기반으로 Covid-19에 대한 수 헥치 안약의 잠재적 메커니즘 탐색

4200

Published on 2021-12-232022-08-31
Journal: Medicine [Category] 유전자 메커니즘, 치료제,

[키워드] activator Analysis Anti-viral applied AutoDock binding affinity biological processe cells chemokine Chinese classic collected Compound compounds coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 disease Cytokine storm Cytoscape software database Diagnosis disease endothelial epidermal epidermal growth factor Functional enrichment analysis GeneCard Genes growth factor guideline hub genes hypoxia immune function immune system include inflammatory storm ingredient interleukin interleukin 17 interleukin 6 Intersection janus Janus kinase KEGG Kyoto mechanism moderate molecular docking molecular mechanism Necrosis network pharmacology Ontology pathway enrichment Pathways phosphatidylinositol phosphatidylinositol 3-kinase PI3K pill plague platform potential mechanism potential therapeutic targets predicted Protein kinase B protein-protein interaction R language receptor Regulation screened severe COVID-19 signaling pathways STAT3 suggested suhexiang pill synergistic T cell T cell receptor target target gene Target genes targets TNF Traditional Chinese medicine Transcription Treatment Tumor tumor necrosis tumor necrosis factor Vascular Viral viral invasion was used
[DOI] 10.1097/MD.0000000000027112 PMC 바로가기 [Article Type] 4200

Prothrombotic Phenotype in COVID-19: Focus on Platelets

Review

Published on 2021-12-202022-10-29
Journal: International Journal of Molecular Sciences [Category] COVID-19, SARS,

[키워드] abnormality activated activation of platelet acute lung injury affecting alteration alveolar capillary Biomarker Blood Cell cell fragment chemokine Coagulation Coagulopathy contribute COVID-19 COVID-19 infection COVID-19 patient COVID-19 patients COVID-19 progression critically ill patients cytokine Cytokine storm D-dimer described elevated endothelial Endothelial cell endothelial injury Evidence fatality fibrinogen focus functions Hemostasis immune response immunothrombosis Infectious disease Inflammation Inflammatory intrinsically involved late stage membrane microthrombi Multi-organ damage NET neutrophil observation P-selectin Pathogenesis phenotype Platelet platelet activation promote prothrombotic SARS-CoV-2 severity sites of inflammation thrombosis vascular permeability von Willebrand factor
[DOI] 10.3390/ijms222413638 PMC 바로가기 [Article Type] Review

Mechanism of Blood–Heart-Barrier Leakage: Implications for COVID-19 Induced Cardiovascular Injury

혈액-심장 장벽 누출의 메커니즘: COVID-19로 인한 심혈관 손상에 대한 시사점

Article

Published on 2021-12-172022-09-10
Journal: International Journal of Molecular Sciences [Category] SARS, 변종,

[키워드] Activation acute respiratory syndrome alteration arising Blood cardiac function cardiac hypertrophy cardiovascular cause cause of death complications of COVID-19 congestive heart failure Corona virus COVID-19 COVID-19 viral myocarditis creatinine kinase isoforms death degrade Deleterious demonstrated determine dysfunction ECHO echocardiography endocardium endothelial Endothelium FITC gamut hallmark HCQ heart failure Hydroxychloroquine induced inhibit interstitium Laboratory leakage Manifestations matrix metalloproteinase matrix metalloproteinases mechanism Mfn2 mice Mitochondria mitochondrial mouse myocarditis novel corona virus Novel coronavirus phenotype Previous studies previous study respiratory Result resulting robust SARS-CoV-2 Severe acute respiratory syndrome shown Signaling subjects synchronous tissue tissue remodeling treated Treatment uncoupling variant viral myocarditis was measured were measured
[DOI] 10.3390/ijms222413546 PMC 바로가기 [Article Type] Article

Acute and Chronic Cardiovascular Manifestations of COVID-19: Role for Endotheliopathy

Review

Published on 2021-12-152022-10-30
Journal: Methodist DeBakey Cardiovascular Journal [Category] COVID-19, MERS, SARS,

[키워드] Adhesion Molecule alteration antioxidant Arrhythmias cardiovascular cause caused cerebrovascular attack chemokines chronic circulating cognitive conditions contribute coronavirus disease COVID-19 Deep venous thrombosis Dementia disease donors edema endothelial Endothelium Evidence expression heart failure homeostasis impairment indicate infiltration Inflammatory cytokine intercellular Invasion manifestation Manifestations Myocardial infarction myocarditis nitric oxide patients with COVID-19 promoted Pulmonary embolism pulmonary fibrosis role SARS-CoV-2 stroke therapeutic therapy Thromboembolism thrombosis Venous Thromboembolism ventricular virus
[DOI] 10.14797/mdcvj.1044 PMC 바로가기 [Article Type] Review

In-vivo evidence of systemic endothelial vascular dysfunction in COVID-19

Observational Study

Published on 2021-12-152022-10-05
Journal: International journal of cardiology [Category] SARS, 임상,

[키워드] 1:1 acute COVID-19 addition approach arteries blinded cardiac complication cardiovascular risk factor Case-control changes in clinical implication Control controls COVID-19 COVID-19 patient COVID-19 symptom decrease Deleterious demographics dysfunction endothelial Endothelial dysfunction endothelial function enrolled Evidence group investigated mechanism Non-invasive participant Patient patients with COVID-19 post infection prognostic reactive SARS-CoV-2 SARS-COV-2 infection scaled significantly lower study groups syndrome systemic Systemic vascular endothelial function. Vascular vascular dysfunction was obtained
[DOI] 10.1016/j.ijcard.2021.10.140 PMC 바로가기 [Article Type] Observational Study