hospitalized COVID-19 patients – Page 11 – Communicable Diseases Research

Liver Injury and Elevated FIB-4 Define a High-Risk Group in Patients with COVID-19

Article

Published on 2021-12-282022-10-30
Journal: Journal of Clinical Medicine [Category] COVID-19,

Final Results of a Randomized, Placebo-Controlled, Two-Arm, Parallel Clinical Trial of Proxalutamide for Hospitalized COVID-19 Patients: A Multiregional, Joint Analysis of the Proxa-Rescue AndroCoV Trial

Endocrinology/Diabetes/Metabolism

Published on 2021-12-252022-10-31
Journal: Cureus [Category] COVID-19,

[키워드] 1:1 95% CI 95% confidence interval ACE2 addition all-cause mortality androgen Androgen receptor angiotensin-converting enzyme 2 antiandrogens Arm ARMS baseline Brazil clinical clinical trial COVID COVID-19 Day demonstrated discharge Drug efficacy effective Efficacy evaluate expression female Final highest hospital Hospital stay Hospitalization hospitalized COVID-19 patient hospitalized COVID-19 patients improvement Inflammatory response interquartile range IQR joint material median mortality rate mortality rates North outcome outcomes oxygen pandemic performed Placebo placebo group preliminary report Prevent proxalutamide randomization randomized clinical trial RCT RCTs reduced reduction in Region Regulation Result risk ratio SARS-CoV-2 score Sepsis South statistical analysis statistically statistically significant stratified by sex study population subject the placebo group TMPRSS2 transmembrane protease serine 2 Trial usual care was performed WHO
[DOI] 10.7759/cureus.20691 PMC 바로가기 [Article Type] Endocrinology/Diabetes/Metabolism

Epidemiological Characteristics of Hospitalized Patients with Moderate versus Severe COVID-19 Infection: A Retrospective Cohort Single Centre Study

Article

Published on 2021-12-232022-11-01
Journal: Diseases [Category] COVID-19,

[키워드] age Analysis ARDS average C-reactive protein CDC Clinical characteristics clinical factor Clinical outcome clinical outcomes Comorbidity conducted COVID-19 COVID-19 severity CRP D-dimer Demographic factors elevated epidemiological Epidemiological factors Factor Factors fatality FIVE Hospitalized hospitalized COVID-19 patient hospitalized COVID-19 patients identify intensive care Intervention Laboratory Laboratory parameters LDH majority male management marker mechanical ventilation moderate Mortality NIV non-invasive ventilation non-severe patient noticeable difference Older Oman Patient prevalent progression reduce resource Respiratory disease retrospective cohort study SARS-CoV-2 selected Sepsis severe COVID-19 illness Severe patient severity single-center steroid syndrome therapeutic therapeutic intervention WBC were assessed white cell with COVID-19
[DOI] 10.3390/diseases10010001 PMC 바로가기 [Article Type] Article

Overweight and Obesity Are Associated With Acute Kidney Injury and Acute Respiratory Distress Syndrome, but Not With Increased Mortality in Hospitalized COVID-19 Patients: A Retrospective Cohort Study

Endocrinology

Published on 2021-12-142022-10-31
Journal: Frontiers in Endocrinology [Category] COVID-19,

[키워드] acute kidney failure Acute kidney injury acute respiratory distress Analysis association Clinical course complications condition COVID-19 during admission evaluate groups Hospital stay hospitalized COVID-19 patient hospitalized COVID-19 patients in-hospital mortality in-hospital mortality rate Increased increased mortality Length malignancy Mortality multicenter multivariate logistic regression obese obesity objective Observational cohort study organ outcome outcomes overweight Patient patients patients hospitalized performed Probability recipients respiratory Result retrospective syndrome with COVID-19 women
[DOI] 10.3389/fendo.2021.747732 PMC 바로가기 [Article Type] Endocrinology

Physical and Psychosocial Well-Being of Hospitalized and Non-Hospitalized Patients With COVID-19 Compared to the General Population in Qatar

Psychiatry

Published on 2021-12-132022-10-31
Journal: Frontiers in Psychiatry [Category] COVID-19,

[키워드] Analysis Anxiety Care carried component Control controls covariates COVID-19 COVID-19 patient COVID-19 patients cross-sectional Depression emotional examined expected explained female gender form functioning General population growth healthy controls Hospitalized hospitalized COVID-19 patients individual Inpatients limitation mental health Older age pandemic Patient Perspective physical Population Prevalence problems psychiatric history Psychological Psychosocial Quality of life quarantined quarantined patients Randomly Resilience resulting scored selected shown stress symptom Support survey three group
[DOI] 10.3389/fpsyt.2021.792058 PMC 바로가기 [Article Type] Psychiatry

Anaemia and enhancement of coagulation are associated with severe COVID-19 infection

Observational Study

Published on 2021-12-012022-10-05
Journal: Scandinavian journal of clinical and laboratory in [Category] 임상,

[키워드] Activation Anaemia analysed anonymously Antithrombin Blood Blood coagulation C reactive protein characteristic Coagulation coagulation test collected complete blood count correlated COVID-19 COVID-19 patient criteria CRP D-dimer D-dimer level Disseminated intravascular coagulation elevated examined fibrinogen First wave FVIII Haemoglobin Helsinki hospitalized COVID-19 patient hospitalized COVID-19 patients ICU ICU admission ICU patient Inflammation Inflammatory marker Inflammatory response information intensive care unit Laboratory leukocyte marker men non-ICU patients pandemic Patient Platelet Presence R 2 reflected Severe COVID-19 Infection severe inflammation severity the patient university was reduced women
[DOI] 10.1080/00365513.2021.2001845 PMC 바로가기 [Article Type] Observational Study

Assessing the potential correlation of polymorphisms in the IL6R with relative IL6 elevation in severely ill COVID-19 patients’

중증 COVID-19 환자에서 IL6R의 다형성과 상대적 IL6 상승의 잠재적 상관 관계 평가

Clinical Trial

Published on 2021-12-012022-09-11
Journal: Cytokine [Category] 바이오마커, 변종, 임상,

[키워드] Affect affecting Analysis Assessing association baseline Baseline assessment baseline level blood sample Blood samples clinical response Clinical studies clinical study clinical variable collected Combination Control correlation COVID-19 COVID-19 patient COVID-19 patients COVID19 COVID19 patients cytokine level cytokine levels Cytokine storm defined determine elevated Elevation Genetic Genetic variant genetic variants Glucose help highest hospitalized COVID-19 patient hospitalized COVID-19 patients hospitalized patient hospitalized patients identify IL-6 IL-6 inhibition IL-6 level IL-6 levels IL6 IL6R interleukin-6 Interpretation mild COVID-19 patient Mortality norm not seen outcome oxygen P-value p-value < 0.01 Participants pathophysiology patient population patients Phase 3 Placebo plasma Plasma levels Pneumonia polymorphism randomized study receiving Regulatory report robust rs2228145 Sequencing analysis serum severe and mild COVID-19 patients severe COVID-19 severe patients severity shown significantly significantly increased supplemental oxygen support tested the patient tradipitant Treatment unlikely variant variants were measured while WHO whole genome Whole genome sequencing
[DOI] 10.1016/j.cyto.2021.155662 PMC 바로가기 [Article Type] Clinical Trial

A comparison between virus- versus patients-centred therapeutic attempts to reduce COVID-19 mortality

COVID-19 사망률을 줄이기 위한 바이러스 중심 치료와 환자 중심 치료 간의 비교

Review

Published on 2021-12-012022-09-10
Journal: Emerging Microbes & Infections [Category] SARS, 치료제,

[키워드] ACE2 acute respiratory disease acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 aging angiotensin angiotensin converting enzyme angiotensin converting enzyme 2 anti-inflammatory treatment anti-inflammatory treatments Antiviral antivirals bind caused changed Comorbidities coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 mortality death rate death rates Dexamethasone dysfunction Effectiveness effort elderly elderly patients enzyme explain hospitalized COVID-19 patient hospitalized COVID-19 patients hospitalized patient hospitalized patients Infection inhibit limit majority Mas receptor Mortality Patient patients patients hospitalized reduce Renin renin-angiotensin system replicative required respiratory Respiratory failure SARS-CoV-2 SARS-CoV-2 viral load Scientific community severe acute respiratory syndrome Coronavirus severe COVID-19 symptoms severity severity of symptom Spike protein syndrome the disease the spike protein therapeutic therapeutic option therapeutic options therapeutic strategy those with comorbidity Tocilizumab Treatment Viral Viral load virus with COVID-19
[DOI] 10.1080/22221751.2021.2006579 PMC 바로가기 [Article Type] Review

Epidemiology and Risk Factors of COVID-19-Related Mortality

Internal Medicine

Published on 2021-12-012022-10-31
Journal: Cureus [Category] COVID-19,

[키워드] Admission analyzed Characteristics Clinical characteristics Clinical findings Comorbidities Comorbidity conducted coronavirus disease Course COVID-19 COVID-19 confirmed patients COVID-19 India COVID-19 mortality COVID-19 patient COVID-19 severity demographic characteristics demographics Department diabete diabetes and hypertension Diabetes Mellitus epidemiological epidemiology and public health Factor Final greater hospital hospitalized COVID-19 patients hypertension identify IMV India intensive care Intervention Invasive mechanical ventilation laboratory data laboratory parameter less Logistic regression analysis Lower Medical Sciences Medicine Mortality multivariate need for oxygen New NIV non-invasive ventilation outcomes oxygen saturation oxygen supplementation pandemic Patient performed predictors presence of comorbidities prognostic Result retrospective risk-factors serum creatinine severe disease Systolic blood pressure the patient therapy Vaccination strategies
[DOI] 10.7759/cureus.20072 PMC 바로가기 [Article Type] Internal Medicine

COVID-19 In-Hospital Mortality in People with Diabetes Is Driven by Comorbidities and Age—Propensity Score-Matched Analysis of Austrian National Public Health Institute Data

Article

Published on 2021-11-302022-10-28
Journal: Viruses [Category] COVID-19, MERS, SARS,