Differential avidity determination of IgG directed towards the receptor-binding domain (RBD) of SARS-CoV-2 wild-type and its variants in one assay: Rational tool for the assessment of protective immunityArticle Published on 2022-11-012022-11-15 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] acute respiratory syndrome avidity binding coronavirus IgG IgG RBD Infection LINE mandatory marker mRNA much lower Omicron variant Protective protective immunity RBD reached Receptor-binding domain recom Line SARS-CoV-2 IgG. SARS-CoV-2 SARS-CoV-2 IgG SARS-COV-2 infection serology Spike protein the receptor-binding domain vaccination variant wild-type WT SARS-CoV-2 [DOI] 10.1002/jmv.28006 PMC 바로가기
Concordance of B- and T-cell responses to SARS-CoV-2 infection, irrespective of symptoms suggestive of COVID-19Article Published on 2022-11-012022-11-15 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 진단, [키워드] absence Analysis anti-IgG antibodies antibody Antibody titer Cellular immune response cellular immunity Cohort correlated correlated strongly COVID COVID-19 COVID-19 pandemic ELISA Evidence Final First wave IgG individual pandemic participant positive antibody response Regulatory response SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 peptide SARS-CoV2 infection spike Symptom symptom response. symptomatic and asymptomatic T cell T-cell T-cell Response TwinsUK were assessed [DOI] 10.1002/jmv.28016 PMC 바로가기
Sensitive Serology Measurements in the Saliva of Individuals with COVID-19 Symptoms Using a Multiplexed ImmunoassayArticle Published on 2022-10-292022-11-15 Journal: The journal of applied laboratory medicine [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] acute respiratory syndrome Antigen benefit causative pathogen collected controls coronavirus coronavirus disease COVID-19 cut-off detect Diagnosis domain group IgG individual individuals with COVID-19 infected individual infected individuals levels of antibody measurement multiplex serology multiplexed immunoassay N-terminal domain nucleocapsid nucleocapsid protein PSO Receptor-binding domain ROC ROC AUC Saliva salivary SARS-CoV-2 sensitive sensitivity Seroconversion serology specificity subjects uninfected uninfected control with COVID-19 [DOI] 10.1093/jalm/jfac073 PMC 바로가기
Longitudinal serologic and viral testing post-SARS-CoV-2 infection and post-receipt of mRNA COVID-19 vaccine in a nursing home cohort-Georgia, October 2020‒April 2021Article Published on 2022-10-272022-11-15 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] administration Antibody detection Antibody Response binding binding antibody blood collection Card Cohort conducted COVID-19 COVID-19 vaccination COVID-19 vaccine Culture detectable dose evaluate evaluated Final first dose geometric IgA antibodies IgA antibody IgG IgG titer IgM antibodies immune response Immunocompromised Infection longitudinal median age mounted mRNA nasal nine nursing home observation participant polymerase chain positive Post-infection Quantitative questionnaire reverse transcription robust RT-PCR SARS-CoV-2 SARS-CoV-2 antibody SARS-COV-2 infection SARS-CoV-2-specific immune response serology specimen subsequent vaccination viral culture [DOI] 10.1371/journal.pone.0275718 PMC 바로가기
Seroprevalence, correlates and kinetics of SARS-CoV-2 nucleocapsid IgG antibody in healthcare workers and nonclinical staff at a tertiary hospital: A prevaccine census studyArticle Published on 2022-10-272022-11-15 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 진단, [키워드] adjusted age Antibody test Asymptomatic category Chemiluminescent assay Comorbidity conducted confidence interval country COVID-19 COVID-19 vaccination determine effective enrolled General population HCW healthcare worker hospital hospital management IgG IgG antibody IgG test implementation increased risk Infection lowest mild symptoms Odds ratio over positive positive PCR test positive SARS-CoV-2 PCR predictor Prevalence preventive measure SAR-CoV-2 SARS-COV-2 infection SARS-CoV-2 nucleocapsid sensitivity Seroprevalence Sex staff Symptoms university was performed [DOI] 10.1371/journal.pone.0267619 PMC 바로가기
Utilization of the Abbott SARS-CoV-2 IgG II Quant Assay To Identify High-Titer Anti-SARS-CoV-2 Neutralizing Plasma against Wild-Type and Variant SARS-CoV-2 VirusesArticle Published on 2022-10-262022-11-15 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] 95% confidence interval Abbott Abbott SARS-CoV-2 IgG acute respiratory syndrome Analysis approach authorization BAU Beta binding antibody unit Canada CCP characterized Chicago Chicago IL clinical trial convalescent convalescent plasma coronavirus COVID-19 COVID-19 convalescent plasma Cutoff Delta disease course drug Emergency EUA evaluated Evidence experiment FDA food Gamma highest hospitalized patient Humoral immunity identify IgG immune IMPROVE Mann-Whitney U method comparisons Neutralization assay Neutralizing neutralizing antibody outcome Patient patient group plaque reduction neutralization plaque reduction neutralization. plasma PRNT quantitative determination required SARS-CoV-2 SARS-CoV-2 antibody selected significantly specimen tested the SARS-CoV-2 time-consuming treat United State utilization variant VLP VoC wild-type with COVID-19 [DOI] 10.1128/spectrum.02811-22 PMC 바로가기
Declining Prevalence of SARS-CoV-2 Antibodies among Vaccinated Nursing Home Residents and Staff Six Months after the Primary BNT162b2 Vaccination Campaign in Belgium: A Prospective Cohort StudyArticle Published on 2022-10-262023-07-10 Journal: Viruses [Category] COVID19(2023년), [키워드] BNT126b2 COVID-19 vaccination elderly IgG IgM nursing home residents SARS-CoV-2 Seroprevalence [DOI] 10.3390/v14112361 PMC 바로가기
Correlation of SARS-CoV-2 Viral Neutralizing Antibody Titers with Anti-Spike Antibodies and ACE-2 Inhibition among Vaccinated IndividualsArticle Published on 2022-10-262022-11-15 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 진단, [키워드] ACE-2 ACE2 ACE2 binding analyzed Angiotensin converting enzyme-2 Anti-RBD IgG Anti-spike anti-spike antibody anti-Spike IgG antibody binding blood collection BNT162b2 calculated collected Concentration correlated correlation correlation coefficient correlation coefficients COVID-19 COVID-19 antibody demonstrated dosing interval examined Fisher group groups IgG individual inhibition interval intervals labor-intensive measure mRNA mRNA-1273 vaccines Neutralizing antibodies neutralizing antibody Neutralizing antibody titer neutralizing antibody titers NTD Participants performed RBD Sample SARS-CoV-2 Secondary analyses Spearman correlation coefficient subgroup tested the median the vaccine titer vaccinated individual vaccination Vaccine vaccinee vaccinees Validity viral neutralization wild-type with COVID-19 women [DOI] 10.1128/spectrum.01315-22 PMC 바로가기
Immunogenicity of inactivated COVID-19 vaccine in patients with autoimmune inflammatory rheumatic diseasesArticle Published on 2022-10-262022-11-15 Journal: Scientific Reports [Category] 진단, [키워드] antibody antibody unit Autoimmune comparable control group COVID-19 vaccine COVID-19 vaccine development defined dose Efficacy General population HCQ IgG IgG antibodies IgG antibody immunogenic immunogenicity immunomodulatory medications inactivated Inflammatory low dose median MTX no difference Patient patients treated positive serum antibodies Progress Protein reduced rheumatic disease second vaccination Seropositivity serum IgG significantly SLE statistical significance statistically significant suppressed treated [DOI] 10.1038/s41598-022-22839-0 PMC 바로가기
Association of Results of Four Lateral Flow Antibody Tests with Subsequent SARS-CoV-2 InfectionArticle Published on 2022-10-262022-11-15 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] 95% confidence interval acute respiratory syndrome adjusted anti-SARS-CoV-2 IgG antibody assist association baseline Cohort cohort study conducted coronavirus Coverage COVID COVID-19 demonstrated disease risk England fire Flow Follow-up hospital IgG Immunity immunoassay immunoassays incidence rate individual Infection investigated Laboratory laboratory assays Lateral Lateral flow device lateral flow device. lateral flow immunoassay Lateral flow test LFIA LFIAs management microbiologically natural infection pandemic participant point-of-care test Poisson regression model Police service Population screening positive predicted prospective cohort study Protective Rapid Rapid test rapid test cassette recruitment Research Result risk risk factor Roche SARS-CoV-2 SARS-CoV-2 disease SARS-CoV-2 IgG SARS-COV-2 infection specificity subsequent Surescreen susceptibility symptomatic SARS-CoV-2 infection Test threshold United Kingdom unvaccinated populations Vaccine was tested [DOI] 10.1128/spectrum.02468-22 PMC 바로가기