neutralizing antibody titers – Page 11 – Communicable Diseases Research

Peptide enzyme‐linked immunosorbent assay (pELISA) as a possible alternative to the neutralization test for evaluating the immune response to IBV vaccine

Research Article

Published on 2021-01-252022-10-28
Journal: BMC veterinary research [Category] Coronavirus, MERS,

Disease‐duration based comparison of subsets of immune cells in SARS CoV‐2 infected patients presenting with mild or severe symptoms identifies prognostic markers for severity

경증 또는 중증 증상을 나타내는 SARS CoV-2 감염 환자의 면역 세포 하위 집합의 질병 기간 기반 비교는 중증도에 대한 예후 마커를 식별합니다.

Comparative Study

Published on 2021-01-162022-09-12
Journal: Immunity, Inflammation and Disease [Category] MERS, SARS, 진단,

[키워드] absence adaptive adaptive immune cells Adaptive immunity addition Analysis analyzed Antibody titer association B cells CD8 T cells Cell dendritic cells determined by disease disease severity event expression flow cytometry follicular forms Frequency functional healthy subject help Humoral immunity Hyperactivation identification identify IgG IL‐6 Imbalance Immune cell immune cells Immune profile India indicated infected patient Infection innate immune cell Innate immune cells Lower lymphocyte Lymphocytes management material maturation mDC mDCs memory B cell memory B cells Mild modulation Monocytes Multivariate analysis Neutralizing antibody titer neutralizing antibody titers NK cells observation Older age pandemic Pathogenesis Patient patient cohort patients positive presenting PRNT PRNT50 Prognostic marker Prognostic markers receptor Result SARS CoV‐2 SARS‐CoV‐2 SARS‑CoV2 Severe case severe cases severe disease severe symptom severity Spectrum subset Symptoms T cell T cells T helper cells therapy understanding
[DOI] 10.1002/iid3.402 PMC 바로가기 [Article Type] Comparative Study

Dynamics of Neutralizing Antibody Titers in the Months After Severe Acute Respiratory Syndrome Coronavirus 2 Infection

중증 급성 호흡기 증후군 코로나 바이러스 2 감염 후 몇 개월 동안 항체 역가 중화의 역학

Major Articles and Brief Reports

Published on 2021-01-152022-09-12
Journal: The Journal of Infectious Diseases [Category] MERS, 진단,

[키워드] accompanied acute respiratory syndrome acute respiratory syndrome coronavirus antibody Antibody dynamics antibody levels Antibody titer Antibody titers Asymptomatic average B cell B cells binding collected coronavirus coronavirus 2 COVID-19 declined determine develop disease domain Dynamics expected fold followed by Frame immune response immune responses Immunity individual Infection initial longitudinal samples Mild moderate-severe Month MOST Neutralizing antibodies neutralizing antibody Neutralizing antibody titer neutralizing antibody titers Other respiratory viruses prospective cohort quantified RBD Receptor-binding domain respiratory respiratory viruses SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 spike Spike protein symptom onset time frames titer total antibodies total antibody Viral viral infection viral spike protein
[DOI] 10.1093/infdis/jiaa618 PMC 바로가기 [Article Type] Major Articles and Brief Reports

Emergency response for evaluating SARS-CoV-2 immune status, seroprevalence and convalescent plasma in Argentina

아르헨티나에서 SARS-CoV-2 면역 상태, 혈청 유병률 및 회복기 혈장 평가를 위한 긴급 대응

Research Article

Published on 2021-01-142022-08-13
Journal: PLoS Pathogens [Category] Biochemistry, 진단, 치료기술,

[키워드] acute and convalescent antibody responses antibody antibody kinetics antibody levels antibody quantification Antibody Response Antibody responses Antibody titers assays Asymptomatic Asymptomatic case Asymptomatic cases Author clinical trial clinical trials Combination compassionate use convalescent convalescent plasma country COVIDAR detect Donor donors ELISA ELISA test Emergency end point enzyme-linked immunosorbent enzyme-linked immunosorbent assay epidemiological evaluate Evolution framework generate Guidance health authorities Health care health care workers health institution hospital hospitalized patient hospitalized patients IgG and IgM IgG antibody IgG antibody titer IgG antibody titers IgM IgM and IgG immune response immune responses Immune status infected individual infected individuals information Kinetics Longitudinal studies longitudinal study management median neutralizing antibody titers nursing homes over pandemic Patient plasma positive correlation powerful tool produced profiles protocol protocols provided public health quantification RBD Receptor binding domain robust SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections Seroconversion seroconversion time serologic assay serologic test serologic testing Spike protein standardized protocol standardized protocols symptomatic and asymptomatic Symptomatic patients symptoms onset Therapies therapy trimer was used
[DOI] 10.1371/journal.ppat.1009161 PMC 바로가기 [Article Type] Research Article

Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses

Research

Published on 2020-12-172022-10-05
Journal: Nature Medicine [Category] SARS, 유전자 메커니즘, 임상,

[키워드] Activation acute respiratory syndrome animal Anti-spike antibody Antibody Response approach AZD1222 boost booster dose Booster vaccine cell activation cellular ChAdOx1 ChAdOx1 nCoV-19 clinical trials complement coronavirus coronavirus vaccine dose doses evaluated exploratory facilitate function functional antibody responses healthy homologous humoral immunogenicity data induce Infection Interim report magnitude multifunctional natural killer neutralizing antibody neutralizing antibody titers Open-label outcome phagocytosis phase Phase 3 Prevent preventing infection priming Randomized controlled trial receive reported Safe SARS-CoV-2 vaccine serology subgroup Support T cell response the vaccine Trial vaccination Vaccine viral spike protein Viral vector Volunteer
[DOI] 10.1038/s41591-020-01179-4 [Article Type] Research

Robust neutralizing antibodies to SARS-CoV-2 infection persist for months

SARS-CoV-2 감염에 대한 강력한 중화 항체는 몇 달 동안 지속됩니다.

Report

Published on 2020-12-042022-09-12
Journal: Science (New York, N.y.) [Category] MERS, SARS, 진단,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Anti-spike Antibody Response Antibody titers binding caused chance Cohort coronavirus COVID-19 COVID-19 case dataset detectable determine global pandemic humoral immune response Immunoglobulin Immunoglobulin G individual infected individual infected individuals Infection Longevity majority Mild mild to moderate Mild-to-moderate moderate Moderate COVID-19 Mount Sinai Mount Sinai Health System neutralization Neutralizing neutralizing antibody neutralizing antibody responses Neutralizing antibody titer neutralizing antibody titers New York City potency Reinfection remains uncertain respiratory robust robustness SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-COV-2 infection SARS-CoV-2 spike protein Science screened severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significantly Spike protein Symptom System the antibody response the SARS-CoV-2 titers Viral viral spike protein virus
[DOI] 10.1126/science.abd7728 PMC 바로가기 [Article Type] Report

Evidence of exposure to SARS-CoV-2 in cats and dogs from households in Italy

이탈리아 가정의 고양이와 개에서 SARS-CoV-2에 노출되었다는 증거

Article

Published on 2020-12-042022-09-12
Journal: Nature Communications [Category] MERS, 진단, 치료기술,

Neutralizing antibody against SARS-CoV-2 spike in COVID-19 patients, health care workers, and convalescent plasma donors

COVID-19 환자, 의료 종사자 및 회복기 혈장 기증자의 SARS-CoV-2 급증에 대한 중화 항체

Technical Advance

Published on 2020-11-192022-09-12
Journal: JCI Insight [Category] SARS, 진단,

[키워드] antibody Antibody testing Cellular immune response cohorts convalescent plasma COVID-19 COVID-19 pathogenesis COVID-19 patients COVID-19 symptoms Donor donors Efficacy evaluate followed by glycoprotein HCWs Health care Health care worker health care workers highest highlight HIV-1 hospitalized patients human antibody response ICU ICU Patients individual individuals intensive care intensive care unit intron lentiviral lentivirus Neutralization assay neutralizing antibody Neutralizing antibody titer neutralizing antibody titers Patient phenotypic phenotypic variation pseudotype pseudotyped Rapid reporter SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 spike SARS-CoV-2 strain secreted serological survey Serological surveys serum the SARS-CoV-2 Treatment Variation Virus neutralization was used
[DOI] 10.1172/jci.insight.143213 PMC 바로가기 [Article Type] Technical Advance

Persistence and decay of human antibody responses to the receptor binding domain of SARS-CoV-2 spike protein in COVID-19 patients

Reports

Published on 2020-10-082022-10-28
Journal: Science Immunology [Category] COVID-19, MERS, SARS,

[키워드] Anti-RBD IgG anti-S antibody blood sample circulating coronavirus correlated COVID patient COVID-19 patient cross-reactivity demonstrated help HKU1 Hospitalization human antibody response IgA IgA response IgG IgG antibody IgG response IgM IgM antibody individual infected individual infected with SARS-CoV-2 Infection infections isotypes tested marker median time Neutralizing antibodies neutralizing antibody titers NL63 no decrease North OC43 Older pandemic Patient plasma Protein RBD Receptor binding domain required response SARS-CoV-2 SARS-CoV-2 RBD SARS-CoV-2 spike protein sensitivity Seroconversion seropositive individual serum antibody response short-lived specificity symptom onset the median the receptor-binding domain the SARS-CoV-2 threshold while
[DOI] 10.1126/sciimmunol.abe0367 PMC 바로가기 [Article Type] Reports

Convalescent plasma transfusion for the treatment of COVID-19: Systematic review

COVID-19 치료를 위한 회복기 혈장 수혈: 체계적인 검토

Article

Published on 2020-09-012022-09-11
Journal: Journal of medical virology [Category] Fulltext, MERS, 진단, 치료제,

[키워드] administration Antibody titers appear available data clinical symptom Clinical symptoms clinical trial clinically conducted convalescent plasma convalescent plasma transfusion (CPT) coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients Critically ill critically ill patients disappearance effective Effectiveness Efficacy eligibility criteria evaluate FIVE increase individuals with COVID-19 knowledge Medline database Mortality multicenter neutralizing antibody Neutralizing antibody titer neutralizing antibody titers outcome pandemic plasma Plasma transfusion protocol reduce reduce mortality reported Safe SARS-CoV-2 SARS-CoV-2 RNA screened searched systematic review the patient therapy Treatment
[DOI] 10.1002/jmv.25961 PMC 바로가기 [Article Type] Article