neutralizing antibody titers – Communicable Diseases Research

Humoral and Cellular Immune Response to Covid-19 Vaccination in Patients with Chronic Graft-versus-Host Disease on Immunosuppression

Article

Published on 2022-11-012022-11-15
Journal: Transplantation and cellular therapy
[Category] SARS, 진단, 치료기술,

Correlation of SARS-CoV-2 Viral Neutralizing Antibody Titers with Anti-Spike Antibodies and ACE-2 Inhibition among Vaccinated Individuals

Article

Published on 2022-10-262022-11-15
Journal: Microbiology Spectrum
[Category] COVID19(2023년), SARS, 진단,

[키워드] ACE-2 ACE2 ACE2 binding analyzed Angiotensin converting enzyme-2 Anti-RBD IgG Anti-spike anti-spike antibody anti-Spike IgG antibody binding blood collection BNT162b2 calculated collected Concentration correlated correlation correlation coefficient correlation coefficients COVID-19 COVID-19 antibody demonstrated dosing interval examined Fisher group groups IgG individual inhibition interval intervals labor-intensive measure mRNA mRNA-1273 vaccines Neutralizing antibodies neutralizing antibodies. neutralizing antibody Neutralizing antibody titer neutralizing antibody titers NTD Participants performed RBD Sample SARS-CoV-2 Secondary analyses Spearman correlation coefficient subgroup tested the median the vaccine titer vaccinated individual vaccination Vaccine vaccinee vaccinees Validity viral neutralization wild-type with COVID-19 women
[DOI] 10.1128/spectrum.01315-22 PMC 바로가기

Protein vaccine NVX-CoV2373 elicits functional T cell immunity

Article

Published on 2022-10-032022-11-15
Journal: The Journal of Clinical Investigation
[Category] COVID19(2023년), SARS, 진단,

Humoral immune response to authentic circulating severe acute respiratory syndrome coronavirus 2 variants elicited by booster vaccination with distinct receptor-binding domain subunits in mice

생쥐에서 뚜렷한 수용체 결합 도메인 소단위로 부스터 백신 접종에 의해 유도된 진정한 순환 중증 급성 호흡기 증후군 코로나바이러스 2 변이체에 대한 체액 면역 반응

Article

Published on 2022-09-012022-09-11
Journal: Journal of medical virology
[Category] COVID19(2023년), MERS, SARS, 변종, 진단,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Antibody titer Antibody titers binding booster booster vaccination circulating comparable coronavirus coronavirus disease Coronavirus disease 2019 domain dose Efficacy elicited expected humoral immune response humoral immune response. Immune escape immune response immunization immunogens induce mice Mutation Neutralizing antibody titer neutralizing antibody titers omicron Protein RBD RBD protein respiratory SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significantly increased Spike protein subunit the spike protein Vaccine vaccine efficacy variant variants virus strain virus strains wild type
[DOI] 10.1002/jmv.27882 PMC 바로가기 [Article Type] Article

Comparison of commercial SARS-CoV-2 surrogate neutralization assays with a full virus endpoint dilution neutralization test in two different cohorts

두 개의 다른 코호트에서 상용 SARS-CoV-2 대리 중화 분석과 전체 바이러스 종말점 희석 중화 테스트의 비교

Article

Published on 2022-09-012022-09-11
Journal: Journal of virological methods
[Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료제,

[키워드] ACE2 angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 antibody Antibody titers biosafety level Cohort cohorts convalescent Convalescent SARS-CoV-2-infected individuals COVID COVID vaccinated individuals Cutoff detect Determination Dilution Endpoint Full virus neutralization test glycoprotein gold gold standard indicate infected individuals Infection Interaction labor labor-intensive level 3 neutralization Neutralization assay neutralization test neutralization tests Neutralizing antibodies neutralizing antibody Neutralizing antibody titer neutralizing antibody titers Qualitative quantitative measurement RBD Receptor binding domain receptor protein Replication SARS-CoV-2 SARS-CoV-2-infected individual spike glycoprotein surrogate surrogate virus neutralization test Surrogate virus neutralization test. sVNT the RBD vaccinated individuals Viral viral spike virus Virus neutralization virus neutralization test VNT
[DOI] 10.1016/j.jviromet.2022.114569 PMC 바로가기 [Article Type] Article

Antibody and Memory B-Cell Immunity in a Heterogeneously SARS-CoV-2-Infected and -Vaccinated Population

Article

Published on 2022-08-302022-11-15
Journal: mBio
[Category] COVID19(2023년), SARS, 변종, 진단,

Severe Acute Respiratory Syndrome Coronavirus 2 Adaptive Immunity in Nursing Home Residents Following a Third Dose of the Comirnaty Coronavirus Disease 2019 Vaccine

Comirnaty 코로나 바이러스 질병 2019 백신의 세 번째 접종 후 요양원 거주자의 중증 급성 호흡기 증후군 코로나 바이러스 2 적응 면역

Article

Published on 2022-08-242022-09-11
Journal: Clinical Infectious Diseases: An Official Publicat
[Category] SARS, 변종, 진단,

Omicron spike function and neutralizing activity elicited by a comprehensive panel of vaccines

포괄적인 백신 패널에 의해 유도된 오미크론 스파이크 기능 및 중화 활성

Article

Published on 2022-08-192022-09-11
Journal: Science (New York, N.y.)
[Category] COVID19(2023년), MERS, SARS, 변종, 진단,

A circular mRNA vaccine prototype producing VFLIP-X spike confers a broad neutralization of SARS-CoV-2 variants by mouse sera

VFLIP-X 스파이크를 생성하는 원형 mRNA 백신 프로토타입은 마우스 혈청에 의한 SARS-CoV-2 변이체의 광범위한 중화를 제공합니다

Article

Published on 2022-08-012022-09-11
Journal: Antiviral Research
[Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술,

[키워드] addition Amino acid amino acid sequence amino acids Antibody titers B.1.1.529 B.1.617.2 balance BNT162b2 boost cellular immune responses cleavage site COVID-19 vaccine Critical D614G detectable Disulfide disulfide bond E484K Evolution of SARS-CoV-2 FIVE flexible glycosylation greater humoral Humoral and cellular immune responses immune responses immunization immunized induce K417N L452R linear linker mice mRNA mRNA vaccine mRNA vaccines mRNA-1273 N501Y neutralization Neutralizing activity Neutralizing antibody response Neutralizing antibody titer neutralizing antibody titers offer pre-fusion producing proline proline substitutions prolines reduced response S-2P SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 variant SARS-CoV-2 variants SARS-CoV-2 virus sequence sera shown spike Spike protein spike trimer stability suggested T478K the spike protein transcript trimer trimeric Vaccine vaccine. Vaccines variant variants variants of concern variants of interest VFLIP virus VOCs VOIs wildtype
[DOI] 10.1016/j.antiviral.2022.105370 PMC 바로가기 [Article Type] Article

rVSV-ΔG-SARS-CoV-2-S vaccine: repeated intramuscular (IM) toxicity, local tolerance, immunogenicity and biodistribution study in NZW rabbits

rVSV-ΔG-SARS-CoV-2-S 백신: NZW 토끼에서 반복되는 근육내(IM) 독성, 국소 내성, 면역원성 및 생체 분포 연구

Article

Published on 2022-08-012022-09-11
Journal: Archives of Toxicology
[Category] COVID19(2023년), MERS, SARS, 비임상, 진단, 치료기술,

[키워드] Administered animals antibody antibody levels Antibody titers Antigen assigned binding biodistribution biodistribution study body temperature body weight breath C-reactive protein change Clinical pathology Clinical signs clinical trial clinical trials correlated COVID-19 detection elicited evaluate Express followed by Gross High-dose high-dose group histopathological iliac lymph node immunogenicity inflammatory reaction injection intervals intramuscular intramuscularly Local local reactions Lymph node mesenteric lymph nodes Necrosis Neutralizing antibodies Neutralizing antibody titer neutralizing antibody titers New Nonclinical ophthalmology pathology Phase 2 platform Reactions repeated RNA Safe Safety SARS-CoV-2 SARS-CoV-2-S significant increase spleen stomatitis supported systemic the vaccine Tolerance Toxicity two group two groups Urinalysis vaccination Vaccine vaccine doses vaccine. Vector-based vaccine vesicular stomatitis vesicular stomatitis virus Viremia VSV was performed
[DOI] 10.1007/s00204-022-03302-5 PMC 바로가기 [Article Type] Article