SARS-CoV-2 Spike Protein Mutations and Escape from Antibodies: A Computational Model of Epitope Loss in Variants of ConcernSARS-CoV-2 스파이크 단백질 돌연변이 및 항체 탈출: 우려되는 변이체에서 에피토프 손실의 계산 모델Article Published on 2021-09-012022-09-10 Journal: Journal of Chemical Information and Modeling [Category] SARS, 변종, 진단, [키워드] antibody Antibody binding antibody binding sites applied changes in characterized concern consequence Contact COVID-19 vaccines D614G develop dominant Efficacy elicited epitope Epitopes escape evade glycosylated helping Host immunogenic immunological immunoreactivity Loss Model Modification modifications molecular molecular dynamics mutant mutants Mutation performed predict Protein raise reactivity Recognition recognize reduce Region regions S-protein S-protein variant SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 spike variants sequence solution spike Structure translate Treatment Vaccine vaccine efficacy Vaccines variant variants Viral viral surface virus while [DOI] 10.1021/acs.jcim.1c00857 PMC 바로가기 [Article Type] Article
RT qLAMP-Direct Detection of SARS-CoV-2 in Raw Sewage미처리 하수에서 SARS-CoV-2의 RT qLAMP-직접 검출Article Published on 2021-09-012022-09-11 Journal: Journal of biomolecular techniques : JBT [Category] SARS, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 amplification Analysis applicability basic Characteristics clinical sample clinical samples complex Concentration coronavirus COVID-19 incidence described detect detection downstream Health health department independent isothermal amplification LAMP Local media N-gene number of sample ORF1a primer primer set primer sets Quantitative Recognition Region reported reverse transcriptase SARS-CoV-2 SARS-CoV-2 detection selected selective severe acute respiratory syndrome Coronavirus sewage significantly target tested to define transcriptase Treatment Viral RNA virus [DOI] 10.7171/jbt.21-32-03-016 PMC 바로가기 [Article Type] Article
HRPZyme Assisted Recognition of SARS-CoV-2 infection by Optical Measurement (HARIOM)광학 측정(HARIOM)을 통한 HRPZyme 지원 SARS-CoV-2 감염 인식Article Published on 2021-09-012022-09-11 Journal: Biosensors & bioelectronics [Category] SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antibody detection Antigen antigen tests assays colorimetric detection Concordance coronavirus COVID-19 detect diagnostics DNAZyme enzymatic assay genetic material Health Policies HRPZyme include Infection less mass Mass screening measurement molecular NAT NATs negative sample nucleic acid On-site diagnostics. PCR positive promise public health Recognition resource respiratory resulting robust Saliva SARS-CoV-2 SARS-COV-2 infection sensitivity Sensitivity and specificity severe acute respiratory syndrome Coronavirus specificity subjects to define Viral Viral protein Viral RNA while [DOI] 10.1016/j.bios.2021.113280 PMC 바로가기 [Article Type] Article
Recognition of COVID-19 from CT Scans Using Two-Stage Deep-Learning-Based Approach: CNR-IEMN †Article Published on 2021-08-312022-10-29 Journal: Sensors (Basel, Switzerland) [Category] COVID-19, MERS, SARS, [키워드] Accuracy addition approach CAP Classifier Community community-acquired pneumonia COVID-19 COVID-19 pandemic CT scan CT scans deep learning first stage multi-tasks strategy Recognition Research sensitivity slice-level classification stages test dataset Topic trained model volumetric Wuhan, China [DOI] 10.3390/s21175878 PMC 바로가기 [Article Type] Article
Associations of SARS-CoV-2 serum IgG with occupation and demographics of military personnel군인의 직업 및 인구 통계와 SARS-CoV-2 혈청 IgG의 연관성Research Article Published on 2021-08-302022-09-12 Journal: PLoS ONE [Category] MERS, SARS, 진단, [키워드] 95% CI aircraft Armed Forces association Biomarker Biomarkers Black race COVID-19 demographic data demographics Disease surveillance elevated ELISA enzyme-linked immunosorbent assay enzyme-linked immunosorbent assays exhibited Follow-up globe highest highlight household size Humoral response humoral responses IgG increased risk Infection information International International airport live SARS-CoV-2 Local moderate MOS neutralizing capacity New York City occupational Odds ratios plaque plaque assays questionnaire Recognition remained Result Risk factors SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 seroprevalence SARS-CoV-2 spike SARS-CoV-2 spike antigen Seropositivity serum serum IgG serum neutralizing capacity significantly spike IgG study population subject were used [DOI] 10.1371/journal.pone.0251114 PMC 바로가기 [Article Type] Research Article
The Role of the PFNA Operon of Bifidobacteria in the Recognition of Host’s Immune Signals: Prospects for the Use of the FN3 Protein in the Treatment of COVID-19숙주의 면역 신호 인식에서 비피도박테리아의 PFNA 오페론의 역할: COVID-19 치료에서 FN3 단백질의 사용에 대한 전망Review Published on 2021-08-262022-09-10 Journal: International Journal of Molecular Sciences [Category] MERS, SARS, 유전자 메커니즘, [키워드] addressed anti-inflammatory drug Anti-inflammatory drugs Bacteria bifidobacteria binding Cluster consequence core genes COVID-19 creation cytokine cytokine receptor Cytokine storms domain domains Evolution FIVE host immune system host-microbe interaction humans immune system immunomodulatory properties immunomodulatory property implicated implication Interaction mechanism microbial motif motifs operon over PFNA operon Protein protein kinase question Recognition resulting role SARS-COV-2 infection Serine species threonine TNF-α transmembrane region [DOI] 10.3390/ijms22179219 PMC 바로가기 [Article Type] Review
SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and stringent CARF ribonuclease activationSCOPE는 유연한 표적화 및 엄격한 CARF 리보뉴클레아제 활성화를 사용하여 유형 III CRISPR-Cas 진단을 가능하게 합니다.Article Published on 2021-08-192022-09-10 Journal: Nature Communications [Category] MERS, SARS, 진단, 치료기술, 치료제, [키워드] 3′ end Activation Assay systems Base pairing binding CARF cleavage cleave complexes CRISPR-Ca CRISPR-Cas systems develop diagnostic diagnostics elements escape flexible Genetic Host immune response include Infectious-disease diagnostics nasal swab Prevent Recognition recognize regions resulting RNA SARS-CoV-2 SARSCoV-2 sensitivities sensitivity subsequent Type type III Variation [DOI] 10.1038/s41467-021-25337-5 PMC 바로가기 [Article Type] Article
Development and Progress in Sensors and Technologies for Human Emotion Recognition인간 감정 인식을 위한 센서 및 기술의 개발 및 진행Review Published on 2021-08-182022-09-10 Journal: Sensors (Basel, Switzerland) [Category] MERS, SARS, 치료기술, [키워드] advancement Algorithms analyzed artificial intelligence build collected communication detect development emotion help Human human emotion Interaction Internet Internet of Things motion analysis pandemic physiological physiological parameters monitoring platform privacy processed Progress proliferation Recognition Research robotics robust scalability security sensor sensors technology Transparency Trust wearable sensors wireless communications [DOI] 10.3390/s21165554 PMC 바로가기 [Article Type] Review
Is My Cough a Cold or Covid? A Qualitative Study of COVID-19 Symptom Recognition and Attitudes Toward Testing in the UKPublic Health Published on 2021-08-182022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] Accuracy Anosmia approach Asymptomatic Attitude Cold collected conducted Contact cough COVID-19 COVID-19 symptoms COVID-19 testing determine engage facilitator female participant General population high temperature illnesses IMPROVE Infection knowledge male Mild symptom NHS offer participant Perceived risk Population positive Qualitative Recognition reducing resources response similarity spread of COVID-19 student Symptom symptom recognition symptoms of COVID-19 Test Testing thematic analysis trace [DOI] 10.3389/fpubh.2021.716421 PMC 바로가기 [Article Type] Public Health
Virtual screening of plant-derived compounds against SARS-CoV-2 viral proteins using computational tools컴퓨터 도구를 사용한 SARS-CoV-2 바이러스 단백질에 대한 식물 유래 화합물의 가상 스크리닝Article Published on 2021-08-102022-09-11 Journal: The Science of the total environment [Category] SARS, 치료제, [키워드] 3-chymotrypsin-like protease addition amyrin antiviral activity Atazanavir AutoDock binding Chloroquine chymotrypsin Chymotrypsin-like protease Compound computational tool Control COVID-19 COVID-19 pandemic delphinidin dicumarol docking Docking studies drug evaluate evaluated explain glycoprotein Glycyrrhetinic acid glycyrrhizin highest affinity host cell host cells hydrogen Hydrogen bond hydrophobic hydrophobic interaction hydrophobic interactions Hydroxychloroquine identify in viral inhibitor Interaction involved lowest M pro molecular molecular docking molecular target nelfinavir new SARS-CoV-2 plants protease Protein Proteins public health Recognition Replication responsible S protein SARS-CoV-2 SARS-CoV-2 viral SARS-CoV2 spike spike glycoprotein taraxasterol target umifenovir Viral protein Viral proteins viral replication viral spike virus was performed were used [DOI] 10.1016/j.scitotenv.2021.146400 PMC 바로가기 [Article Type] Article