Coagulation profile of COVID-19 patients admitted to the ICU: An exploratory studyICU에 입원한 COVID-19 환자의 응고 프로파일: 탐색적 연구Research Article Published on 2020-12-152022-08-13 Journal: PLoS ONE [Category] Biochemistry, MERS, SARS, 치료기술, [키워드] abnormality addressed alteration anticoagulation Antithrombin aPTT baseline both groups change characterized Coagulation coagulation tests complex Conventional COVID-19 patient D-dimer Day decrease exploratory study fibrinogen Fibrinogen levels fibrinolysis fibrinolytic groups hypercoagulability ICU in both group in both groups INR Laboratory test Laboratory tests less Longitudinal evaluation magnitude median objective organ dysfunction Patient plasma plasminogen Platelet Protein protein C protein S remained Result severity slight increase SOFA SOFA score study period two groups were measured with COVID-19 [DOI] 10.1371/journal.pone.0243604 PMC 바로가기 [Article Type] Research Article
Risk factors for COVID-19 patients with cardiac injury: pulmonary ventilation dysfunction and oxygen inhalation insufficiency are not the direct causes코로나19 심장부상 위험인자: 폐환기부전과 산소흡입부족은 직접적인 원인이 아니다Research Paper Published on 2020-12-152022-09-10 Journal: Aging (Albany NY) [Category] 바이오마커, [키워드] Admission analyzed assessment Biomarker cardiac injury cause Characteristics Chest clinical laboratory collected community-acquired pneumonia confirmed case coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient death defined develop distress Dyspnea Factor failure hypertension independent risk factor independent risk factors Injury laboratory data logistic regression model no significant difference Older age outcome oxygen PaO Patient patients with COVID-19 Pneumonia Prognostic value pulmonary ventilation reported respiratory rates risk factor Risk factors serum severe COVID-19 severe disease severe patients significantly significantly more Society SOFA SOFA score Treatment upper reference limit ventilation dysfunction [DOI] 10.18632/aging.104148 PMC 바로가기 [Article Type] Research Paper
Comparison of 2 Triage Scoring Guidelines for Allocation of Mechanical VentilatorsResearch Published on 2020-12-142022-10-29 Journal: JAMA Network Open [Category] Coronavirus, MERS, SARS, [키워드] 95% CI Admission Admissions age agreement allocation applied approach assessment calculated Characteristics clinical assessment cohort study collected conducted coronavirus disease criteria Critically ill determine Elective surgery exposure failure finding guideline hospital hospital discharge implication Importance initial intensive care intensive care unit interquartile range knowledge lowest male measure Mechanical mechanical ventilation median New York objective outcome pandemic participant Patient Philip Point Population proportion recognizing Relevance reported resources Result retrospective cohort study Scoring setting SOFA SOFA score state survival survival rate the mean Triage used data ventilator were assessed white [DOI] 10.1001/jamanetworkopen.2020.29250 PMC 바로가기 [Article Type] Research
Risk factors for severe COVID-19 in middle-aged patients without comorbidities: a multicentre retrospective studyResearch Published on 2020-12-072022-10-30 Journal: Journal of Translational Medicine [Category] COVID-19, MERS, [키워드] 95% CI abnormality addition Admission ARDS AUC Characteristics China clinician Coagulation collected data Comorbidities Comorbidity Complication complications conducted coronavirus COVID-19 COVID-19 patient COVID-19 patients D-dimer died early treatment elevated Factor greater hospital incidence lymphocyte management middle-aged multicentre Multivariable regression neutrophil NLR organ Patient patient with COVID-19 patients reliability resource Result Retrospective study risk factor Risk factors SARS-CoV-2 severe COVID-19 significant difference SOFA [DOI] 10.1186/s12967-020-02655-8 PMC 바로가기 [Article Type] Research
Severe infection due to the SARS-CoV-2 coronavirus: Experience of a tertiary hospital with COVID-19 patients during the 2020 pandemicObservational Study Published on 2020-12-012022-10-05 Journal: Medicina intensiva [Category] SARS, 임상, [키워드] Admission age APACHE II arterial assisted ventilation Automatic Bacterial Care carried Characteristics Cohort Comorbidities complications COVID-19 Deceased Demographic variables experience Fisher exact test Frequency General population HFO high-flow oxygen therapy hospital hypertension IMV incidence Infection initial Insuficiencia respiratoria Invasive mechanical ventilation laboratory data lack males Mann-Whitney Mechanical mechanical ventilation medians obesity Oxygen therapy Oxygenation pandemic PaO parameters Patient patients patients with COVID-19 Pneumonia Prognostic marker required respiratory Respiratory failure severity single-center SOFA survivor the patient the SARS-CoV-2 turn variables Ventilación mecánica Ventilation was used Wilcoxon test with COVID-19 [DOI] 10.1016/j.medin.2020.05.018 PMC 바로가기 [Article Type] Observational Study
Hospital Resources May Be an Important Aspect of Mortality Rate among Critically Ill Patients with COVID-19: The Paradigm of GreeceArticle Published on 2020-11-202022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] Acute hypoxemic respiratory failure acute respiratory distress acute respiratory distress syndrome Admission ARDS aspect coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient Critical care Critically ill patient determine Greece high mortality rate hospital hospital resource hospital resources ICU Ill intensive care interquartile range IQR limitation moderate Mortality mortality rates outcome pandemic PaO paradigm Patient patients patients with COVID-19 performed Prognosis prospective observational study provided Rate reported resource resources Sequential Organ Failure Assessment severe ARDS SOFA syndrome the disease [DOI] 10.3390/jcm9113730 PMC 바로가기 [Article Type] Article
Association of SARS-CoV-2 genomic load trends with clinical status in COVID-19: A retrospective analysis from an academic hospital center in New York CityResearch Article Published on 2020-11-172022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] 24 hour America assessment clinical status correlation cycle decrease diagnosed with COVID-19 duration of symptoms failure genomic hospital inclusion criteria increase in independent Infectious disease initial inverse correlation IQR median nasopharyngeal New York City Patient patients with COVID-19 Pneumonia positive Prognostic value reflected Research question Retrospective analysis retrospective cohort study RT-PCR SARS-CoV-2 sequential test Society SOFA SOFA score statistically significant subsequent threshold was used [DOI] 10.1371/journal.pone.0242399 PMC 바로가기 [Article Type] Research Article
Corticosteroid therapy for coronavirus disease 2019-related acute respiratory distress syndrome: a cohort study with propensity score analysisResearch Published on 2020-11-102022-11-01 Journal: Critical Care [Category] COVID-19, SARS, [키워드] 95% CI 95% confidence interval acute respiratory distress age analyzed Antiviral treatment ARDS ARDS patient calculate caused CIs Clinical practice Cohort cohort study Comorbidities coronavirus disease Coronavirus disease 2019 Corticosteroid corticosteroid therapy corticosteroid treatment Corticosteroids COVID-19 COVID-19 patient Cox regression analysis Cox regression model dose enrolled hazard ratio Hospital admission HRs In-hospital death in-hospital mortality Invasive mechanical ventilation IQR low-dose corticosteroid median Methylprednisolone Mortality Organ failure outcome Patient patients with ARDS per day Primary outcome Propensity score propensity score analysis reduced risk reduction in Respiratory Support Result retrospective risk risk of death severe acute respiratory syndrome coronavirus 2 Sex single-center SOFA SOFA score standard treatment systemic corticosteroid therapy Treatment viral RNA clearance were used [DOI] 10.1186/s13054-020-03340-4 PMC 바로가기 [Article Type] Research
Risk factors for the critical illness in SARS-CoV-2 infection: a multicenter retrospective cohort studyResearch Published on 2020-10-212022-10-28 Journal: Respiratory Research [Category] COVID-19, MERS, [키워드] Admission age alanine aminotransferase Area Aspartate transaminase assessment Blood urea nitrogen breath Care Combination COVID-19 COVID-19 patient Critical Critically ill Curve determine Dyspnea elevated enrolled Factor failure fibrinogen Health hospital Hospitalized ICU identify independent risk factor intensive care Leukocytosis Logistic regression lymphopenia management marker multicenter Older performed positive patient reported resources Result retrospective cohort study risk factor Risk factors SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 nucleic acid SOFA SOFA score the patient total bilirubin ventilator Wuhan [DOI] 10.1186/s12931-020-01492-z PMC 바로가기 [Article Type] Research
Blood purification therapy with a hemodiafilter featuring enhanced adsorptive properties for cytokine removal in patients presenting COVID-19: a pilot studyResearch Published on 2020-10-122022-11-01 Journal: Critical Care [Category] COVID-19, MERS, [키워드] Acute kidney injury acute renal injury Administered Adsorption adsorptive property adverse events AKI attenuate baseline biochemical bleeding Blood purification calculated characterized Combination Complication Concentration correlated COVID-19 Critically ill patient cytokine cytokine removal decrease disorders dose EBP Endpoint evaluated expected expected mortality feasible feature filtration fraction ICU IL-6 Infection Inflammation IQR Kruskal-Wallis test Local median mitigate Mortality mortality rate Multiorgan Multiorgan dysfunction multiple organ dysfunction multiple organ failure occurred Occurrence organ function outcome Patient patients patients with COVID-19 pilot study presenting Prevent Prospective Study purification receiving reduction reduction in renal function Result RRT serum significant decrease significantly SOFA SOFA score Support systemic systemic inflammation the mean therapy Thromboembolism treated Treatment Variation Vascular venous were recorded with COVID-19 [DOI] 10.1186/s13054-020-03322-6 PMC 바로가기 [Article Type] Research