Integrated multiomics analysis to infer COVID-19 biological insightsarticle Published on 2023-01-312024-09-05 Journal: Burma Med J [Category] update2024, [키워드] metabolomics Proteins proteomics Systems biology [DOI] 10.1038/s41598-023-28816-5 PMC 바로가기 [Article Type] article
Alterations in platelet proteome signature and impaired platelet integrin α IIb β 3 activation in patients with COVID-19Original Article Published on 2023-01-282024-09-05 Journal: Journal of thrombosis and haemostasis : JTH [Category] update2024, [키워드] COVID-19 platelet activation proteomics SARS-CoV-2 Thromboinflammation [DOI] 10.1016/j.jtha.2023.01.018 PMC 바로가기 [Article Type] Original Article
Proteomics Profiling Reveals Regulation of Immune Response to Salmonella enterica Serovar Typhimurium Infection in Mice단백질체 프로파일링은 쥐에서 살모넬라 엔테리카 세로바르 타이피무리움 감염에 대한 면역 반응의 조절을 밝혀냅니다.Article Published on 2023-01-242024-08-22 Journal: Infection and Immunity [Category] 살모넬라증, [키워드] genetic regulation immune response mass spectrometry mouse proteome proteomics S. Typhimurium Salmonella
Gene-by-gene screen of the unknown proteins encoded on Plasmodium falciparum chromosome 3Article Published on 2023-01-182024-08-27 Journal: Cell Syst [Category] 말라리아, [키워드] BioID evolution of genes kinetochore knock sideways malaria mitosis nucleus orphan genes Plasmodium falciparum protein function proteomics SKA taxon-specific proteins.
Proteomic Discovery of Plasma Protein Biomarkers and Development of Models Predicting Prognosis of High-Grade Serous Ovarian Carcinomaarticle Published on 2023-01-172024-09-05 Journal: Molecular & Cellular Proteomics [Category] update2024, [키워드] aHR, adjusted hazard ratio AUC, area under the receiver operating characteristic curve CI, Confidence interval enzyme-linked immunosorbent assay FDR, false discovery rate FIGO, Federation of Gynecology and Obstetrics GO, Gene ontology GSN, gelsolin HGSOC, high-grade serous ovarian carcinoma high-grade serous carcinoma iBAQ, intensity-based absolute quantification IDS, interval debulking surgery MS, mass spectrometry NAC, neoadjuvant chemotherapy OS, overall survival Ovarian neoplasms PARP, poly(ADP-ribose) polymerase PDS, primary debulking surgery PFS, progression-free survival PRMT1, protein arginine methyltransferase 1 Prognosis proteomics SIGLEC14, sialic acid–binding Ig-like lectin 14 SND1, staphylococcal nuclease, tudor domain containing 1 VCAN, versican [DOI] 10.1016/j.mcpro.2023.100502 PMC 바로가기 [Article Type] article
An integrated metabolomic and proteomic approach for the identification of covalent inhibitors of the main protease (Mpro) of SARS-COV-2 from crude natural extractsArticle Published on 2023-01-152022-11-15 Journal: Talanta [Category] SARS, 유전자 메커니즘, 치료제, [키워드] Analysis applied approach baicalein binding carried catalytic characteristic Chinese complementary complex Compound Covalent binder Cys145 database drug target electrophilic Final functional HIS163 HIS164 His41 independent inhibitor inhibitors Ion knowledge M pro M(pro) mass mass spectrometry maturation metabolomic metabolomics Michael molecular dynamics MPro nucleophilic peptide platform polyprotein protease protein-ligand Proteins proteomic proteomics residue SARS-CoV-2 Scutellaria baicalensis tested the SARS-CoV-2 [DOI] 10.1016/j.talanta.2022.123824 PMC 바로가기
Integrative systems immunology uncovers molecular networks of the cell cycle that stratify COVID‐19 severityResearch Article Published on 2023-01-132024-09-05 Journal: Journal of medical virology [Category] update2024, [키워드] cell cycle associated molecules COVID‐19 severity proteomics SARS‐CoV‐2 systems immunology transcriptomics [DOI] 10.1002/jmv.28450 PMC 바로가기 [Article Type] Research Article
Proteomics Investigation of Diverse Serological Patterns in COVID-19article Published on 2023-01-052024-09-05 Journal: Molecular & Cellular Proteomics : MCP [Category] update2024, [키워드] C1, complement 1 cellular immunity CLIA, chemiluminescence immunoassay COVID-19 COVID-19, Coronavirus disease 2019 DEP, differentially expressed protein EHR, electronic hospital record HDL-C, high-density lipoprotein cholesterol Inflammation IQR, interquartile range LDL-C, low-density lipoprotein cholesterol nAb, Neutralizing Antibody nonVac, nonvaccinated PCA, principal component analysis proteomics R1, 1-year follow-up R2, 2-year follow-up RT-PCR, reverse-transcriptase polymerase-chain-reaction serology TG, triglyceride TMT, tandem mass tag Vac, vaccinated [DOI] 10.1016/j.mcpro.2023.100493 PMC 바로가기 [Article Type] article
SARS-CoV-2 replication in airway epithelia requires motile cilia and microvillar reprogrammingArticle Published on 2023-01-052023-07-11 Journal: Cell [Category] COVID19(2023년), [키워드] airway epithelial cells cilia COVID-19 microvilli organoids protein kinases proteomics respiratory synctital virus respiratory virus SARS-CoV-2 [DOI] 10.1016/j.cell.2022.11.030 PMC 바로가기
Mass spectrometry detection of monkeypox virus: Comprehensive coverage for ranking the most responsive peptide markersArticle Published on 2023-01-012023-06-09 Journal: Proteomics [Category] 원숭이두창, [키워드] detection DIA markers mass spectrometry Monkeypox proteomics virus [DOI] 10.1002/pmic.202200253