Covid-19 Symptomatic Patients with Oral Lesions: Clinical and Histopathological Study on 123 Cases of the University Hospital Policlinic of Bari with a Purpose of a New ClassificationArticle Published on 2021-02-132022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] Analysis anticoagulant therapy classification clinical correlation COVID-19 diagnosed disorders early stage Evolution feature four group histopathological initial lesion lesions Necrosis New oral oral lesions oral ulcers Patient patients Policlinic Stage Symptom the timing Therapies therapy thrombosis tissues ulcerative university vessel was performed [DOI] 10.3390/jcm10040757 PMC 바로가기 [Article Type] Article
Meta-analysis of host transcriptional responses to SARS-CoV-2 infection reveals their manifestation in human tumorsSARS-CoV-2 감염에 대한 숙주 전사 반응의 메타 분석은 인간 종양에서의 발현을 나타냅니다Meta-Analysis Published on 2021-01-282022-09-01 Journal: Scientific Reports [Category] 유전자 메커니즘, 진단, [키워드] A549 activated adenocarcinoma bronchial epithelial cell Calu Calu-3 Cancer cancer cell Cancer cells Cell cell line cell line data common Data integration defined eight epithelial cells Gene regulatory networks histopathological Host immune response host response host responses Host transcriptional response IL-6 immune Immune cell infiltration immune response immune responses implicated Infection Inflammation interferon signaling lung adenocarcinoma lung cancer manifested model system Molecular biology NF-κB NHBE pathway Pathways Patient reveal SARS-CoV-2 SARS-COV-2 infection similarity subset the cell the SARS-CoV-2 Therapeutic strategies therapeutic strategy transcriptional transcriptomic Tumor Tumour immunology type II interferon Viral viral infection viral infections virus viruses [DOI] 10.1038/s41598-021-82221-4 PMC 바로가기 [Article Type] Meta-Analysis
Fatal pulmonary arterial thrombosis in a COVID-19 patient, with asymptomatic history, occurred after swab negativizationCase Report Published on 2021-01-062022-10-29 Journal: Thrombosis Journal [Category] COVID-19, [키워드] Analysis Antithrombotic Asymptomatic Asymptomatic COVID-19 Asymptomatic individuals asymptomatic patient bilateral pneumonia Cardiomyopathy Complete contribute COVID-19 COVID-19 patient death develop diagnostic distress drug early treatment Evidence form heart heterogeneous histopathological hypercoagulability Inflammatory kidneys lesion liver lung lung tissue main pulmonary artery Mild moderate Modification occurred pathological change pathophysiological mechanism Patient Post-mortem provide recommendation reported risk SARS-CoV-2 SARS-CoV-2 infected individual SARS-COV-2 infection spleen Swab Symptoms thrombosis thrombotic thrombotic complication Thrombotic complications Thrombus Topic Treatment Vascular was performed whole body [DOI] 10.1186/s12959-020-00255-6 PMC 바로가기 [Article Type] Case Report
Cutaneous manifestations in patients with coronavirus disease 2019: clinical and histological findings2019년 코로나바이러스 질환 환자의 피부 발현: 임상 및 조직학적 소견Article Published on 2021-01-012022-09-11 Journal: Human pathology [Category] SARS, 치료기술, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody appear biopsy caused characterized coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Cutaneous cutaneous manifestation Cutaneous manifestations dermatitis dermatopathology dermis described descriptions detectable detection differential diagnosis feature flu-like symptoms histological histopathological histopathological feature Hospitalized hypersensitivity reaction Immunochemistry immunohistochemistry immunostaining In situ hybridation In situ hybridization Inflammatory Initially interface dermatitis manifestation Mild nucleocapsid protein pathology Patient patients worldwide performed perivascular polyclonal presenting Protein Rash rashes reported respiratory retrieved SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-infected patient severe acute respiratory syndrome Coronavirus skin skin biopsies skin biopsy skin lesions spongiosis university university hospital Viral Viral RNA virus [DOI] 10.1016/j.humpath.2020.10.011 PMC 바로가기 [Article Type] Article
Is SARS-CoV-2 present in the periodontium? A post-mortem studySARS-CoV-2가 치주에 존재합니까? 사후 연구Comment Published on 2021-01-012022-09-11 Journal: Evidence-based dentistry [Category] 치료기술, [키워드] age Analysis applicability Autopsy blunt blunt dissection Chain Reaction Comorbidities Comorbidity connective tissue COVID-19 infection COVID-19 test criteria cross cross-sectional cross-sectional study cycle threshold Cycle threshold value Data analysis death Deceased Descriptive analysis Effect eosin exclusion criteria facial first molar FIVE General population genetic material Haematoxylin histopathological hospitalisation individual individuals individuals with COVID-19 insertion intensive care intensive care unit Invasive mechanical ventilation Medicine men molecular analysis nasopharyngeal Nasopharyngeal swab nasopharyngeal swab test nuclear nuclear pleomorphism onset of symptom periodontal tissue polymerase chain polymerase chain reaction positive Post-mortem Real-time reverse transcriptase polymerase chain reaction responsible reverse transcriptase rRT-PCR salivary Sample size SARS-CoV-2 School Seven smoking smoking status test result tooth transcriptase university virus was collected was obtained was performed was used women [DOI] 10.1038/s41432-021-0184-0 PMC 바로가기 [Article Type] Comment
Pathological changes in the lungs and lymphatic organs of 12 COVID-19 autopsy casesClinical Medicine Published on 2020-12-292022-10-30 Journal: National Science Review [Category] COVID-19, [키워드] alteration Analysis Autopsy changes changes in Characteristics COVID-19 COVID-19 patients Critically ill Diffuse alveolar damage dysregulation evaluated Evidence expression facilitate fibrosis histopathological Histopathology IL-1β IL-6 immune Immune cell immune disorder Inflammation Inflammatory Inflammatory factor Injury interstitial IP-10 lesion lung Lungs Lymph node lymph nodes lymphatic organ lymphopenia Macrophage Macrophage infiltration pathological SARS-CoV-2 spleen the disease tissue TNFα [DOI] 10.1093/nsr/nwaa247 PMC 바로가기 [Article Type] Clinical Medicine
Simulation of the Clinical and Pathological Manifestations of Coronavirus Disease 2019 (COVID-19) in a Golden Syrian Hamster Model: Implications for Disease Pathogenesis and Transmissibility골든 시리아 햄스터 모델에서 코로나바이러스 질병 2019(COVID-19)의 임상 및 병리학적 징후 시뮬레이션: 질병 발병 및 전염성에 대한 의미Article Published on 2020-12-032022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] MERS, SARS, 진단, 치료법, [키워드] ACE2 Activation adaptive airway alveolar damage angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 animal Antibody titer Antibody titers Apoptosis atrophy binding Blood change chemokine clinical Clinical sign Clinical signs Contact convalescent serum coronavirus COVID-19 Diffuse alveolar damage docking expression hamster hamsters histopathological Histopathology immunoprophylaxis initial intestinal involvement with Koch's postulates Laboratory lung Lung pathology lung viral load lymphoid mammal manifestation molecular docking Mortality Mutation Neutralizing antibody titer nonsynonymous option organ Pathogenesis pathological pathology performed physiological proliferative rapid breathing Receptor-binding domain resulting SARS-CoV-2 Serum neutralizing antibody significant decrease Simulation Spike protein spleen suggested the receptor-binding domain tissue tissue repair titer Transmission Treatment vaccination Viral Viral load viral nucleocapsid protein virus virus titer viruses weight loss [DOI] 10.1093/cid/ciaa325 PMC 바로가기 [Article Type] Article
Periodontal tissues are targets for Sars-Cov-2: a post-mortem studyOther Published on 2020-11-262022-10-30 Journal: Journal of Oral Microbiology [Category] COVID-19, [키워드] age alteration Analysis analyzed Autopsies Autopsy average conducted coronavirus SARS-CoV-2 COVID-19 COVID-19 case COVID-19 pandemic COVID-19 positive patients cytoplasm determinant female patient FIVE histopathological identify infection control invasive Laboratory test nuclear pleomorphism nucleus oral manifestation Other patients periodontal periodontal tissue positive Post-mortem post-mortem biopsy respiratory impairment responsible RNA RT-PCR SARS-CoV-2 Seven Spread surpassed target the SARS-CoV-2 tissue tissues Transmission vacuolization virus [DOI] 10.1080/20002297.2020.1848135 PMC 바로가기 [Article Type] Other
The other side of COVID‐19 pandemic: Effects on male fertilityReview Published on 2020-11-222022-11-01 Journal: Journal of medical virology [Category] COVID-19, SARS, [키워드] ACE Affect affected cause caused cellular entry changes in Clinical data component coronavirus COVID‐19 Effect expression functional genital tract histopathological increases in induce lung male male genital system male genital tract mechanism novel coronavirus disease organ outbreak pandemic Pandemics pathway RAS Respiratory disease SARS‐CoV‐2 TMPRSS2 virus [DOI] 10.1002/jmv.26667 PMC 바로가기 [Article Type] Review
Surgical Mask Partition Reduces the Risk of Noncontact Transmission in a Golden Syrian Hamster Model for Coronavirus Disease 2019 (COVID-19)외과용 마스크 파티션은 코로나바이러스 질병 2019(COVID-19)에 대한 골든 시리아 햄스터 모델에서 비접촉 전파의 위험을 줄입니다Article Published on 2020-11-192022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 aerosol-generating procedures benefit caused changes chloride closed system coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 transmission experimental evidence exposure to expression hamster hamsters healthcare histopathological Histopathology in vivo infected individuals investigated isolator lack manifestation Mask Masks medium Model nuclei nucleocapsid antigen Partition porous prevention of COVID-19 reduced respiratory respiratory droplet Respiratory droplets respiratory tract tissues SARS-CoV-2 separated severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significantly specimen Support surgical tested Transmission transmitted Viral Viral load [DOI] 10.1093/cid/ciaa644 PMC 바로가기 [Article Type] Article