Downregulation of CD45 Signaling in COVID-19 Patients Is Reversed by C24D, a Novel CD45 Targeting Peptide
Medicine
[키워드] Activation
acute respiratory syndrome
bind
Breast cancer
CD45
Cell
Coronavirus-2
COVID-19
COVID-19 patient
demonstrated
function
healthy volunteers
Hypothesis
immune
Immune suppression
immune system
Immunosuppression
in viral
inhibited
interfere
intracellular signaling
leukocytes
modulating
mononuclear cell
novel
Patient
patients
PBMC
PBMCs
peptide
Peripheral blood
Phosphorylation
potential therapeutic target
predominant
Protein
reported
required
rescued
SARS-CoV-2
Signaling
signaling pathway
similarity
Src family of tyrosine kinases
T cell receptor
targeting
tested
therapeutic
transmembrane
tyrosine
tyrosine phosphatase
virus
[DOI] 10.3389/fmed.2021.675963 PMC 바로가기 [Article Type] Medicine
[DOI] 10.3389/fmed.2021.675963 PMC 바로가기 [Article Type] Medicine