Respiratory Coronavirus

[키워드] Activation acute lung injury administration Alanine ALT animal Anti-inflammatory anti-inflammatory property Aspartate aminotransferase AST BALB/c mice canine Cell Chinese coronavirus disease COVID-19 cytokine Cytokines ELISA evaluated expressed expression H1N1 IAV IFN-α IFN-β IFN-γ IL-10 IL-6 in vitro Indigo Naturalis Inflammation Influenza influenza A virus influenza viruses inhibited inoculated interferon interferon γ interleukin-6 intranasally IP-10 kidney liver liver index Lung injury lung tissue MCP-1 MDA mechanism mice monocyte chemoattractant protein-1 Mortality MPO multi organ failure myeloperoxidase nitric oxide organ pandemic peritoneal macrophage Protein RANTES reduced regulated Respiratory Coronavirus Result SARS-CoV-2 secreted significantly significantly increased spleen staining suppressed survival rate T cell TCM TLR4 TNF-α toll-like receptor 4 treat treated Treatment tumor necrosis factor-α viral replication virus replication were recorded
[DOI] 10.1186/s13020-020-00415-w PMC 바로가기 [Article Type] Research