Piezoelectric point-of-care biosensor for the detection of SARS-COV-2 (COVID-19) antibodiesResearch article Published on 2022-08-012022-10-05 Journal: Sensing and Bio-Sensing Research [Category] 진단, 치료기술, [키워드] analyzed antibodies antibody Antigen assays caused changes COVID-19 diagnose diagnostic diagnostics different disease disease facilitate faster feature Frequency global pandemic high mortality In-vitro Novel coronavirus Piezoelectric biosensor platform POC biosensor point-of-care resulting SARS SAW selective sensitivity sensor specific disease Surface acoustic waves tested the disease the vaccine Vaccine development [DOI] 10.1016/j.sbsr.2022.100510 [Article Type] Research article
Invariant in variants변이의 불변Article Published on 2022-08-012022-09-11 Journal: Ultrasonics [Category] 변종, [키워드] Biochemistry coronavirus demonstrated Effectiveness experiment flexible Frequency help IMPROVE mechanism mutate pandemic pathogen physical the vaccine ultrasound wave variant variants viral spike [DOI] 10.1016/j.ultras.2022.106749 PMC 바로가기 [Article Type] Article
In silico SARS-CoV-2 vaccine development for Omicron strain using reverse vaccinology역백신학을 이용한 오미크론 균주에 대한 In silico SARS-CoV-2 백신 개발Article Published on 2022-08-012022-09-11 Journal: Genes & genomics [Category] COVID19(2023년), SARS, 변종, [키워드] 3D structure 3D Structures ACE2 ACE2 receptor acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 allergenicity angiotensin angiotensin converting enzyme angiotensin converting enzyme 2 antigenic antigenicity applied B cell epitope B cell epitopes B.1.1.529 binding collected coronavirus develop Efficacy effort enzyme epitope Epitopes estimation final vaccine construct Health Organization in silico MHC I MHC II molecular docking analysis Mutation non-allergenic non-toxic omicron pandemic Physicochemical properties physicochemical property predict predicted Prevent profile RaptorX reduce reverse vaccinology SARS-CoV-2 SARS-CoV-2 vaccine second secondary structure secondary structures selected severe acute respiratory syndrome Coronavirus solubility Spread stability Structure tested the vaccine Toxicity Vaccine vaccine candidate vaccine construct Vaccine design Vaccines variant viral genome sequences virus VoC was performed were used WHO wild type World Health Organization [DOI] 10.1007/s13258-022-01255-8 PMC 바로가기 [Article Type] Article
COVID-19 and pregnancy: clinical outcomes; mechanisms, and vaccine efficacyReview article Published on 2022-08-012022-10-05 Journal: Translational research : the journal of laboratory [Category] SARS, 변종, 임상, [키워드] ACE2angiotensin-converting enzyme 2 acute respiratory distress syndrome addressed angiotensin-converting enzyme 2 ARDSacute respiratory distress syndrome cells Characteristics clinical trials complications COVID-19 COVID-19 pandemic developmental effective Effectiveness Efficacy Entry mechanism feature genomic growth highlight Immune escape immune response increased risk indicate individual investigated mechanism mechanisms mRNA-based COVID-19 vaccine Neonates pathology placental Pregnancy pregnant Preterm birth proteomic RASRenin-angiotensin system renin-angiotensin system risk SARS-CoV-2 SARS-CoV-2 disease SARS-COV-2 infection SARS-CoV-2severe acute respiratory syndrome coronavirus-2 severe acute respiratory syndrome coronavirus-2 Stillbirth the vaccine Transmissibility Vaccine Vaccines variants of concern variants of SARS-CoV-2 vector VOCvariants of concern [DOI] 10.1016/j.trsl.2022.08.007 [Article Type] Review article
Sputnik-V reactogenicity and immunogenicity in the blood and mucosa: a prospective cohort study혈액 및 점막의 스푸트니크-V 반응원성과 면역원성: 전향적 코호트 연구Article Published on 2022-08-012022-09-11 Journal: Scientific Reports [Category] SARS, 임상, 진단, 치료기술, 치료법, [키워드] adverse event adverse events alteration assays baseline Blood blood platelet collected condition correlated COVID-19 COVID-19 vaccine COVID-19 vaccines detectable diagnostic dose Effect Efficacy Elevation elicited Gam-COVID-Vac growth Heterologous immune immunization immunology injection Kazakhstan Local Mild-to-moderate mucosal nasal Nasopharyngeal swab nasopharyngeal swabs oncogene outcome participant performed Platelet count populations potentially life-threatening proportion prospective cohort study Questionnaires reactogenic reactogenicity reduced regimen regulated reported SARS-CoV-2 SARS-CoV-2 immunity seroconversion rate Serum level serum levels subject systemic adverse event systemic reactions the vaccine vaccination Vaccine vector Virus neutralization while [DOI] 10.1038/s41598-022-17514-3 PMC 바로가기 [Article Type] Article
Immune Persistence and Safety After SARS-CoV-2 BNT162b1 mRNA Vaccination in Chinese Adults: A Randomized, Placebo-Controlled, Double-Blind Phase 1 Trial중국 성인에서 SARS-CoV-2 BNT162b1 mRNA 백신 접종 후 면역 지속성 및 안전성: 무작위, 위약 대조, 이중 맹검 1상 시험Clinical Trial Published on 2022-08-012022-09-12 Journal: Advances in therapy [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] Administered Antibody titer BNT162b1 candidate vaccine Chinese COVID declined dose geometric mean titer GMT GMTs immune persistence maintain mRNA mRNA vaccine NAb neutralizing antibody nucleoside-modified mRNA Older participant Participants persistence Phase 1 Registered reported Safety safety profile SARS-CoV-2 SARS-CoV-2 vaccine Serious Adverse Event the vaccine vaccination vaccination schedule Vaccine was determined [DOI] 10.1007/s12325-022-02206-1 PMC 바로가기 [Article Type] Clinical Trial
Anxiety disorders, COVID-19 fear, and vaccine hesitancyResearch article Published on 2022-08-012022-10-05 Journal: Journal of anxiety disorders [Category] 진단, [키워드] adverse effect Anxiety Anxiety Disorder anxiety disorders coronavirus COVID-19 COVID-19 vaccine development disorders Effectiveness Efficacy examined Factor greater group groups Influenza less not differ predict predictor Prevent PROTECT reducing the vaccine Vaccine Vaccine hesitancy Vaccines [DOI] 10.1016/j.janxdis.2022.102598 [Article Type] Research article
Efficacy and safety of mRNA SARS-CoV-2 vaccines in lung transplant recipients폐 이식 환자에서 mRNA SARS-CoV-2 백신의 효능 및 안전성Article Published on 2022-08-012022-09-12 Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] adverse event analyzed Antibody Response BNT162b2 vaccine clinical study conducted Control controls COVID-19 dose Efficacy and safety evaluated Fever humoral immune response IgG Immunosuppression IMPROVE in both groups increase in Japan Logistic regression lung transplant lung transplantation mRNA mRNA vaccination mRNA vaccine mRNA-1273 vaccine nonrandomized Open-label percentage plasma concentration positive antibody response Prospective Study recipient recruited regimen SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 vaccination SARS-CoV-2 vaccine serology significantly the antibody response the vaccine university vaccination Vaccine Vaccines was measured while [DOI] 10.1016/j.jiac.2022.04.019 PMC 바로가기 [Article Type] Article
Robust humoral and cellular immune responses in long-term convalescent COVID-19 individuals following one-dose SARS-CoV-2 inactivated vaccinationSARS-CoV-2 비활성화 백신 접종 후 장기간 회복 중인 COVID-19 개인의 강력한 체액 및 세포 면역 반응Article Published on 2022-08-012022-09-11 Journal: Frontiers in Immunology [Category] SARS, 변종, 진단, [키워드] addition anti-S Antigen antigen-specific T cell Antigen-specific T cells B cell booster caused CD4 Cellular immune response characterized convalescent COVID-19 death demonstrated Efficacy exhibited frequencies Frequency healthy healthy individual healthy individuals Hospitalization humoral IFN-γ IgG IL-2 immune immune responses inactivated Inactivated vaccine individual infected patient Infection long-term convalescent. NAbs Neutralizing antibodies neutralizing antibody neutralizing capacity RBD IgG RBD-specific IgG recipients recovered patient recovered patients robust SARS-CoV-2 SARS-CoV-2 inactivated vaccine SARS-CoV-2 RBD SARS-CoV-2 vaccine severe disease significantly significantly higher significantly increased single dose subject T cell T cell response T cell responses T cells the vaccine TNF-α utility vaccination Vaccine vaccine-induced immune response variants variants of concern VoC VOCs wild type [DOI] 10.3389/fimmu.2022.966098 PMC 바로가기 [Article Type] Article
A multidisciplinary effort to increase COVID-19 vaccination among the older adults노년층의 코로나19 예방접종 확대를 위한 다학제적 노력Article Published on 2022-08-012022-09-11 Journal: Frontiers in Public Health [Category] 변종, [키워드] addressed Adults adverse effect analyzed approach case study clinics Cluster Community COVE COVID-19 COVID-19 vaccination COVID-19 vaccine Data analysis dose effort elderly expressed facilitated healthcare worker Healthcare workers implementation information initiated Intention morbidity and mortality multidisciplinary team Older older adult Phase 1 Phase I primary care reduce reported risk of infection significantly Singapore SMS the vaccine vaccinate vaccination vaccination appointment vaccination appointments Vaccination program Vaccine Vaccine hesitancy vaccine promotion variants of concern Volunteer [DOI] 10.3389/fpubh.2022.904161 PMC 바로가기 [Article Type] Article