Neutralizing antibodies – Page 131 – Communicable Diseases Research

Persistence and decay of human antibody responses to the receptor binding domain of SARS-CoV-2 spike protein in COVID-19 patients

Reports

Published on 2020-10-082022-10-28
Journal: Science Immunology [Category] COVID-19, MERS, SARS,

The SARS-CoV-2 Spike Glycoprotein Biosynthesis, Structure, Function, and Antigenicity: Implications for the Design of Spike-Based Vaccine Immunogens

Immunology

Published on 2020-10-072022-11-01
Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS,

An approach to lifting self-isolation for health care workers with prolonged shedding of SARS-CoV-2 RNA

SARS-CoV-2 RNA의 장기간 배출이 있는 의료 종사자를 위한 자가 격리 해제 방법

Original Paper

Published on 2020-10-062022-09-10
Journal: Infection [Category] MERS, SARS, 치료기술, 치료제,

[키워드] approach assumed authority Blood blood sample Blood samples carriers Cell culture Clinical improvement collected convalescent COVID-19 Ct-value Ct-values ELISA test European Guidance HCW Health authority Health care worker healthcare worker healthy infectiousness interval Isolation lack median medical records nasopharyngeal negative RT-PCR neutralization test Neutralizing antibodies neutralizing antibody non-infectiousness onset of symptoms Oropharyngeal oropharyngeal swab oropharyngeal swabs Particle PCR tests PCR-confirmed performed positive positive PCR positive PCR result positive RT-PCR Public remained respiratory respiratory specimen respiratory specimens Result RNA RT-PCR RT-PCR Ct RT-PCR tests SARS-COV-2 infection SARS-CoV-2 RNA SARS-CoV-2 viral RNA SARS-CV-2 Self-isolation serum neutralization test serum samples Swab swab sample symptom onset tested the patient threshold Viral virion virus growth virus isolation was performed
[DOI] 10.1007/s15010-020-01530-4 PMC 바로가기 [Article Type] Original Paper

Virological and Serological Discordant Profiles in COVID-19 Pneumonia: Two Atypical Clinical Cases

Immunology

Published on 2020-10-022022-11-01
Journal: Frontiers in Immunology [Category] COVID-19, MERS,

Progress and Pitfalls in the Quest for Effective SARS-CoV-2 (COVID-19) Vaccines

Immunology

Published on 2020-10-022022-11-01
Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS,

[키워드] adverse effects adverse events of special interest (AESI) antibody antibody dependent enhancement (ADE) approach approaches Bacillus Calmette-Guérin (BCG) candidate candidate vaccine Cell mediated immunity clinical trial Coalition for Epidemic Preparedness Innovations (CEPI) COVID-19 Critical effective Efficacy effort Ensuring globe groups Human immune immune response immunize immunogenic impacts in healthy individual Innate immunity knowledge likelihood Neutralizing antibodies occur pandemic Progress PROTECT quest required Safe safety profile SARS-CoV-2 SARS-CoV-2 vaccine shown Spike protein stimulate Surveillance T cell response Trial Vaccine Vaccine development virus
[DOI] 10.3389/fimmu.2020.579250 PMC 바로가기 [Article Type] Immunology

SARS-CoV-2 antibodies, serum inflammatory biomarkers and clinical severity of hospitalized COVID-19 patients

Research article

Published on 2020-10-012022-10-05
Journal: Journal of Clinical Virology [Category] SARS, 바이오마커,

[키워드] analyzed anti-RBD antibody approaches association Blood C reactive protein Clinical data Clinical severity collected comparable Complete correlation COVID-19 COVID-19 patient COVID-19 severity CRP demographic different time point domain ELISA event exhibited ferritin GFP hospitalized COVID-19 patient hospitalized patient ICU ICU patient IgG IgGs IL-6 inflammatory biomarkers intensive care interleukin-6 investigated LDH Neutralizing antibodies neutralizing antibody non-ICU patient onset of symptom Patient platform pro-inflammatory biomarkers Protein Pseudotyped virus RBD recognizing Result retrieved retrospective SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 IgG SARS-CoV-2 RBD sera serum inflammatory biomarker Serum level suggested Support were measured
[DOI] 10.1016/j.jcv.2020.104611 [Article Type] Research article

Update on newer approaches to prevent or treat COVID-19 infection: What we all need the most right now!!

COVID-19 감염을 예방하거나 치료하기 위한 새로운 접근 방식에 대한 업데이트: 지금 우리 모두에게 가장 필요한 것!!

Review

Published on 2020-10-012022-09-12
Journal: Transfusion and apheresis science : official journ [Category] MERS, SARS, 진단,

Ad26 vector-based COVID-19 vaccine encoding a prefusion-stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses

Prefusion-stabilized SARS-CoV-2 Spike 면역원을 인코딩하는 Ad26 벡터 기반 COVID-19 백신은 강력한 체액 및 세포 면역 반응을 유도합니다

Article

Published on 2020-09-282022-09-10
Journal: NPJ Vaccines [Category] 변종, 비임상, 임상,

[키워드] Ad26 Ad26.COV2.S best binding breath Cellular immune response cellular immunity cleavage clinical trial coronavirus coronavirus S coronavirus S protein COVID-19 COVID-19 vaccine Critical demonstrated development effective element elicited etiologic agent evaluated folded protein furin furin cleavage site Heterologous hinge region humoral Humoral immunity IFN-γ induce Intervention membrane-bound mice Mutation Neutralizing Neutralizing antibodies neutralizing antibody non-neutralizing antibody observation peptide peptides Phase I prefusion conformation proline prolines prophylactic measure prophylactic measures Protein S protein S protein-based vaccine SARS-CoV-2 SARS-CoV-2 vaccine shown signal peptide signal peptides spike Substitution substitutions Th1 the S protein translated Vaccine Vaccines Viral viral infection viral replication viral surface wild-type
[DOI] 10.1038/s41541-020-00243-x PMC 바로가기 [Article Type] Article

Intercellular Transmission of Naked Viruses through Extracellular Vesicles: Focus on Polyomaviruses

Review

Published on 2020-09-262023-08-29
Journal: Viruses [Category] E형 간염,

[키워드] BKPyV en bloc transmission Extracellular vesicles JCPyV MCPyV Neutralizing antibodies Polyomavirus SV40 TSPyV
[DOI] 10.3390/v12101086 PMC 바로가기 [Article Type] Review

Cross-Protection against MERS-CoV by Prime-Boost Vaccination Using Viral Spike DNA and Protein

Vaccines and Antiviral Agents

Published on 2020-09-232022-10-30
Journal: Journal of Virology [Category] COVID-19,

[키워드] addition amino acids binding cause cell-mediated immune response Cellular immune response cellular receptor Combination Coronavirus vaccines Coronaviruses cross-neutralization cross-protection cross-protective demonstrated develop DNA DNA plasmid DNA viruses effective examined expected Heterologous high mortality human DPP4 humoral immunization immunized immunized mice induce interferon MERS-CoV mice Middle East mouse Mutation Neutralizing antibodies neutralizing antibody platform priming promote Protein provided RBD Recombinant protein regimen respiratory syndrome coronavirus RNA virus S-protein S-pseudovirion sequence sera severe respiratory illness spike spike glycoprotein strain subunit suggested the receptor-binding domain vaccination Vaccine Vaccine development Vaccines variant viral infection viral strain viruses wild-type
[DOI] 10.1128/JVI.01176-20 PMC 바로가기 [Article Type] Vaccines and Antiviral Agents