Development and evaluation of a rapid and simple diagnostic assay for COVID-19 based on loop-mediated isothermal amplification루프 매개 등온 증폭을 기반으로 한 신속하고 간단한 코로나19 진단 분석법 개발 및 평가Research Article Published on 2020-11-042022-08-13 Journal: PLoS Neglected Tropical Diseases [Category] Biochemistry, COVID-19, SARS, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus battery caused clinical clinical evaluation coronavirus COVID-19 COVID-19 case detect development Diagnosis diagnostic Direct highly pathogenic human coronavirus isothermal amplification less Loop-mediated isothermal amplification nasal swab Novel coronavirus outbreak Patient performed platform Pneumonia point-of-care Prevent Probability Rapid required respiratory reverse transcription RNA extraction RT-LAMP rural areas SARS-CoV SARS-CoV-2 SARS-CoV-2 pneumonia severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 specimens spread of COVID-19 Surveillance Swab Treatment Viral Viral RNA [DOI] 10.1371/journal.pntd.0008855 PMC 바로가기 [Article Type] Research Article
Low-dose chest CT for diagnosing and assessing the extent of lung involvement of SARS-CoV-2 pneumonia using a semi quantitative scoreResearch Article Published on 2020-11-032022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, SARS, [키워드] age analysed Analysis calculated Chest CT clinical consolidation correlated correlation cough determine diabete diagnosing Dyspnea feature Fever GGO ground-glass opacity group groups hypertension impairment low-dose lung involvement male Mann-Whitney test material mean value no symptom objective Patient positive RT-PCR Predictive Prognosis pulmonary involvement Quantitative respiratory rate Result risk factor RT-PCR SARS-COV-2 infection SARS-CoV-2 pneumonia score severity shown significantly Spearman Symptom the mean was performed was used were recorded [DOI] 10.1371/journal.pone.0241407 PMC 바로가기 [Article Type] Research Article
Coagulation biomarkers are independent predictors of increased oxygen requirements in COVID-19응고 바이오마커는 COVID-19에서 증가된 산소 요구량에 대한 독립적인 예측자입니다.Article Published on 2020-11-012022-09-11 Journal: Journal of thrombosis and haemostasis : JTH [Category] 바이오마커, [키워드] 95% CI 95% confidence interval activated Admission adult COVID-19 patient adverse outcome adverse outcomes age Analysis Antigen association baseline Biomarker Biomarkers BMI body mass body mass index C-reactive protein Coagulation Comorbidity confounder contribute COVID-19 COVID-19 patients CRP D-dimer D-dimers death diabetes factor VIII fibrinogen Follow-up FVIII hazard ratio hypercoagulability hypertension independent predictor leucocytes metabolic syndrome outcomes oxygen Oxygen requirement Oxygen requirements partial thromboplastin time Pathogenesis plasma Platelet platelet-poor plasma Platelets Pneumonia Predictive Prothrombin time regression analysis risk SARS-CoV-2 pneumonia SARS-CoV2 Sex significantly subdistribution syndrome THROMBOPLASTIN thrombosis univariable von Willebrand factor vWF [DOI] 10.1111/jth.15067 PMC 바로가기 [Article Type] Article
Severe SARS-CoV-2 pneumonia in a 58-year-old patient with HIV: a clinical case report from the Republic of CyprusHIV에 감염된 58세 환자의 중증 SARS-CoV-2 폐렴: 키프로스 공화국의 임상 사례 보고Case Reports Published on 2020-11-012022-09-11 Journal: Journal of medical virology [Category] 치료제, [키워드] Case report Cyprus Patient SARS-CoV-2 pneumonia [DOI] 10.1002/jmv.26053 PMC 바로가기 [Article Type] Case Reports
Retinal involvement and ocular findings in COVID-19 pneumonia patientsArticle Published on 2020-10-152022-10-04 Journal: Scientific Reports [Category] MERS, SARS, 치료기술, 치료법, [키워드] absence affected alteration change chorioretinitis Co-infection Coagulation system Cohort conducted Conjunctival swab corneal sensitivity COVID-19 COVID-19 infection COVID-19 pneumonia patient cross-sectional demonstrated described evaluated Eye manifestations females Hospitalized ICU immune Infectious disease intensive care male median age ocular Pathogens Patient patients patients hospitalized PCR analysis Pneumonia provided Retinal SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pneumonia severe COVID-19 Severe COVID-19 pneumonia tap viral infection viral spread with COVID-19 [DOI] 10.1038/s41598-020-74446-6 PMC 바로가기 [Article Type] Article
COVID-19 pneumonia in kidney transplant recipients-Where we are?신장 이식 환자의 COVID-19 폐렴-우리는 어디에 있습니까?Review Published on 2020-10-012022-09-11 Journal: Transplant infectious disease : an official journa [Category] SARS, 치료제, [키워드] Azithromycin Brazil China coronavirus disease Coronavirus disease 2019 country COVID COVID-19 diagnosed discharge drug heparin Human Hydroxychloroquine hydroxychloroquine and azithromycin immune Immunosuppression Infectious diseases involved kidney kidney and liver transplantation kidney transplant liver Liver transplantation nonpathogen nonpathogen-specifc immune parameters. Novel coronavirus novel coronavirus SARS-CoV-2 parameters patient symptom Patient symptoms patient with SARS-CoV-2 Pneumonia recipient reduction report reported respiratory Respiratory failure Respiratory illness SARS-CoV-2 pneumonia Support symptomatic therapy treated [DOI] 10.1111/tid.13306 PMC 바로가기 [Article Type] Review
Hospital-acquired SARS-CoV-2 pneumonia in a person living with HIVCase Reports Published on 2020-09-212022-10-31 Journal: International Journal of STD & AIDS [Category] COVID-19, SARS, [키워드] Antiretroviral therapy Combination ART (cART), HIV (Human immunodeficiency virus), Location, Other, South America, Viral disease HIV hospital Hospital stay Infection intraventricular management outcome SARS CoV-2 SARS-CoV-2 pneumonia Symptom with HIV [DOI] 10.1177/0956462420957528 PMC 바로가기 [Article Type] Case Reports
Strongyloides infection manifested during immunosuppressive therapy for SARS-CoV-2 pneumoniaSARS-CoV-2 폐렴에 대한 면역억제 치료 중 나타난 Strongyloides 감염Case Reports Published on 2020-09-102022-09-12 Journal: Infection [Category] MERS, SARS, 진단, [키워드] abdominal pain bilateral pneumonia Complication Corticosteroid Corticosteroids Course cytokine cytokine inhibitor cytokine inhibitors Dexamethasone eosinophil Eosinophil count Evidence full recovery High dose High-dose Hyperinflammatory Immunosuppression immunosuppressive Immunosuppressive agents immunosuppressive therapy Infection infections interstitial intravenous intravenous dose involved Italian itching Ivermectin Latent infections manifested Pathogenesis Patient Pneumonia public health Reactivation risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pandemic SARS-CoV-2 pneumonia severe COVID-19 severe disease steroid Steroids Stool examination Strongyloides stercoralis strongyloidiasis suggested therapy Tocilizumab treated Treatment [DOI] 10.1007/s15010-020-01522-4 PMC 바로가기 [Article Type] Case Reports
Hydroxychloroquine and dexamethasone in COVID-19: who won and who lost?Review Published on 2020-09-092022-11-01 Journal: Clinical and Molecular Allergy : CMA [Category] COVID-19, [키워드] “cytokine storm” adopted alveolar anti-inflammatory drug Antiviral ARDS benefit cause CCL-2 Chloroquine Combination Control Controlled COVID-19 COVID-19 case COVID-19 patient COVID-19 treatment cytokine Cytokine storm syndrome death deaths Dexamethasone effective Efficacy Evidence Evidence Based Medicine FDA gold hospital Hospitalized hospitalized patients Hydroxychloroquine IL-12 IL-6 IL-8 immunological include indication Lopinavir Lopinavir—ritonavir lung damage mechanically ventilated NIH non-randomized offer patients hospitalized patients receiving oxygen patients with COVID-19 performed Pharmacologic provide provided RCT RCTs reduced reducing reducing mortality Remdesivir reported respiratory retrospective SARS-CoV-2 SARS-CoV-2 pneumonia service Severe case Standard the disease the WHO therapy therapy for COVID-19 TNFα Treatment treatment for COVID-19 Trial turn University of Oxford Vascular with COVID-19 [DOI] 10.1186/s12948-020-00132-7 PMC 바로가기 [Article Type] Review
Bacterial and viral co-infections in patients with severe SARS-CoV-2 pneumonia admitted to a French ICUResearch Published on 2020-09-072022-10-28 Journal: Annals of Intensive Care [Category] COVID-19, [키워드] Acinetobacter administration Atypical Bacteria Bacterial bacterial co-infection baseline Co-infection Combination COVID-19 COVID-19 patient Critically ill patient Culture distribution empiric antibiotic Enterobacteriaceae French Haemophilus influenzae ICU ICU admission invasive mechanical involved median monotherapy Moraxella catarrhalis pathogenic pathogenic bacteria Patient PCR performed Pneumonia positive predictor Prevalence prognostic Pseudomonas aeruginosa quartile Respiratory failure Result Retrospective study RT-PCR SARS-CoV-2 SARS-CoV-2 pneumonia SARSCoV-2 severe SARS-CoV-2 Staphylococcus aureus Streptococcus pneumoniae viruses [DOI] 10.1186/s13613-020-00736-x PMC 바로가기 [Article Type] Research