Early risk markers for severe clinical course and fatal outcome in German patients with COVID-19독일 COVID-19 환자의 심각한 임상 경과 및 치명적인 결과에 대한 조기 위험 표지자Research Article Published on 2021-01-292022-09-10 Journal: PLoS ONE [Category] MERS, 치료기술, [키워드] acute respiratory distress acute respiratory distress syndrome Admission analysed ARDS Biomarker Biomarkers body mass body mass index Clinical course clinical manifestation clinical manifestations Comorbidities Comorbidity Corona Course COVID-19 death develop disease early stage early stages Extrapulmonary Fever group help high risk identify increased risk interleukin-6 lymphocyte marker medication non-survivor Non-survivors not differ not different on admission outcome parameter Patient patients with ARDS patients with COVID-19 Predictive respiratory distress risk risk markers SARS-CoV-2 serum significantly significantly more subgroup subgroups survival survivor Survivors syndrome therapeutic option two groups Viral viral spread Virus Disease [DOI] 10.1371/journal.pone.0246182 PMC 바로가기 [Article Type] Research Article
Cardiac Troponin I association with critical illness and death risk in 726 seriously ill COVID-19 patients: A retrospective cohort studyResearch Paper Published on 2021-01-292022-10-29 Journal: International Journal of Medical Sciences [Category] COVID-19, MERS, [키워드] adjusted Admission age Analysis analyzed association cardiac cardiac troponin Clinical characteristics coronavirus disease Coronavirus disease 2019 (COVID-19) COVID-19 Critical Critically ill patient critically ill patients death demonstrated Factor help hypersensitive hypersensitive cardiac troponin I (hs-cTnI) independent risk factor Laboratory test lactate dehydrogenase lactate dehydrogenase (LDH) LDH Medical resources Mortality mortality risk non-survivor outcome parameter Patient predict Predictive procalcitonin Prognosis respiratory rate retrospective cohort study risk risk factor ROC Curve serious COVID-19 severe acute respiratory syndrome coronavirus (SARS-CoV-2) severe group survivor Symptom Tongji Hospital Treatment troponin Wuhan, China [DOI] 10.7150/ijms.53641 PMC 바로가기 [Article Type] Research Paper
Risk factors for mortality of coronavirus disease-2019 (COVID-19) patients in two centers of Hubei province, China: A retrospective analysis중국 후베이성 두 곳의 코로나19(COVID-19) 환자 사망 위험 요인: 후향적 분석Research Article Published on 2021-01-282022-09-10 Journal: PLoS ONE [Category] 치료기술, [키워드] 95% confidence interval Acute cardiac injury acute respiratory distress acute respiratory distress syndrome Admission age analyzed approach ARDS assist cardiac injury Characteristics China CK-MB clinical clinician collected Comorbidities Comorbidity Complication Computed tomography conducted consolidation coronavirus coronavirus disease COVID-19 COVID-19 patients Cox regression analysis creatine creatine kinase death Dyspnea enrolled Factor Frequency global pandemic hazard ratio hemoglobin identify independent risk factor independent risk factors indicated Laboratory Lactate lactate dehydrogenase LDH Mortality multivariate multivariate Cox regression analysis non-survivor Older on admission outbreak overall mortality Patient patient age PCT poor prognosis predictor procalcitonin radiological radiological features renal respiratory distress Respiratory distress syndrome Result Retrospective analysis risk factor Risk factors survivor syndrome the median Treatment variable variables Wuhan Wuhan, China [DOI] 10.1371/journal.pone.0246030 PMC 바로가기 [Article Type] Research Article
Serum Prealbumin Concentrations, COVID-19 Severity, and Mortality: A Systematic Review and Meta-AnalysisMedicine Published on 2021-01-262022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95% CI affected age assist Biomarker C-reactive protein Combined Concentration conducted coronavirus disease COVID-19 COVID-19 patient COVID-19 severity defined disease severity effect size Egger heterogeneity ICU Inflammation intensive care Malnutrition management marker mean difference mechanical ventilation Meta-analysis Mortality non-survivor Patient patients with COVID-19 prealbumin receiving review risk stratification searched sensitivity analysis serum severe disease severity significantly significantly lower SMD systematic review t -test turn Viral load Web of Science with COVID-19 [DOI] 10.3389/fmed.2021.638529 PMC 바로가기 [Article Type] Medicine
Subcutaneous emphysema and pneumomediastinum in patients with COVID-19 disease; case series from a tertiary care hospital in PakistanOriginal Paper Published on 2021-01-202022-11-01 Journal: Epidemiology and Infection [Category] COVID-19, MERS, [키워드] acute respiratory distress Admission age assisted ventilation average Care case sery Chest clinical symptom Complication Convalescent plasma therapy coronavirus disease Corticosteroid cough COVID patient COVID-19 COVID-19 ARDS patients Critically ill Dyspnoea emphysema Fever highest hospital Hospital stay incidence Inflammatory response initial interquartile range Invasive mechanical ventilation lung damage lung disorder median men non-invasive ventilation non-survivor outcome PaO Patient patients died patients of COVID-19 patients with COVID-19 PEEP Pneumomediastinum Positive end-expiratory pressure positive pressure ventilation Seven subcutaneous emphysema survivor Symptom syndrome the patient Tocilizumab triggered [DOI] 10.1017/S095026882100011X PMC 바로가기 [Article Type] Original Paper
ICU Admission Levels of Endothelial Biomarkers as Predictors of Mortality in Critically Ill COVID-19 Patients중환자실 COVID-19 환자의 사망률 예측인자로서의 내피 바이오마커의 ICU 입원 수준Observational Study Published on 2021-01-192022-09-11 Journal: Cells [Category] MERS, 바이오마커, 임상, [키워드] Adhesion Molecule Admission Ang-1 angiopoietin association Biomarker Biomarkers characteristic Cohort COVID-19 COVID-19 patient Critically ill critically ill COVID-19 patients determine died E-selectin elevated endothelial endothelial damage endothelial marker Endothelial markers endotheliopathy greater growth factor hospitalized patients ICU ICU admission Ill intensive care intensive care unit intercellular intercellular adhesion molecule involved Kaplan–Meier analysis Level marker Mortality non-survivor observational study predict Probability Prognostic value receiver operating characteristic ROC ROC Curve sE-selectin selectin sICAM-1 significantly sP-selectin suggested survival survivor Survivors Vascular vascular endothelial growth factor VEGF von Willebrand factor was used were assessed were measured [DOI] 10.3390/cells10010186 PMC 바로가기 [Article Type] Observational Study
The risk factors associated with COVID-19-Related death among patients with end‐stage renal diseaseObservational Study Published on 2021-01-192022-10-04 Journal: BMC Nephrology [Category] 임상, [키워드] 95% confidence interval adjusted Admission age Alborz association AST Blood blood test CIs Comorbidities Concentration conducted confounding factors COVID-19 COVID-19 patient COVID-19 patients COVID-19-related death death Demographic factors disease distribution End‐stage renal disease ESRD Factor Factors group hazard high risk higher risk Hospitalized HRs identify in-hospital mortality increased risk Iran Kidney failure diseases lack less log-rank lymphocyte medical record Mortality multivariable Cox regression neutrophil count non-survivor O2 Saturation Older parameter Patient predict Ratio renal Result retrospective cohort study risk factor Risk factors Sex significant difference suggested survival survivor Survivors Symptoms univariable [DOI] 10.1186/s12882-020-02221-w PMC 바로가기 [Article Type] Observational Study
Mortality risk of COVID-19 in elderly males with comorbidities: a multi-country studyResearch Paper Published on 2021-01-152022-10-28 Journal: Aging (Albany NY) [Category] COVID-19, MERS, SARS, [키워드] accounted age Analysis analyzed cause Cerebrovascular disease China chronic obstructive Cohort Comorbidities Comorbidity COPD COVID-19 COVID-19 pandemic COVID-19 patient Critical care Dexamethasone elderly European Factors female Gender had more high mortality Hospital stay incidence male morbidity and mortality Mortality non-survivor North America Patient populations pulmonary disease Region regions Remdesivir risk risk factor Risk factors risk of COVID-19 SARS-CoV-2 Shortness of breath significantly higher significantly shorter Support survival time survivor Survivors symptom onset [DOI] 10.18632/aging.202456 PMC 바로가기 [Article Type] Research Paper
Red Blood Cell Distribution Width, Disease Severity, and Mortality in Hospitalized Patients with SARS-CoV-2 Infection: A Systematic Review and Meta-AnalysisArticle Published on 2021-01-142022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] 95% CI acute respiratory syndrome Admission age assist Biomarker Blood Cell conducted coronavirus coronavirus disease correlation COVID-19 COVID-19 patient database defined disease severity distribution effect size Egger’s test end point Evidence extreme Gender hematological ICU Infection intensive care mean difference Meta-analysis Mortality non-survivor outcome parameter Patient patients with SARS-CoV-2 Predictive Red red blood cell distribution width Research review risk stratification routine tests SARS-CoV-2 SARS-COV-2 infection searched selected sensitivity analysis severe disease severity significantly significantly higher SMD systematic review turn Web of Science Whole blood width with COVID-19 [DOI] 10.3390/jcm10020286 PMC 바로가기 [Article Type] Article
Elevated plasma IL-6 and CRP levels are associated with adverse clinical outcomes and death in critically ill SARS-CoV-2 patients: inflammatory response of SARS-CoV-2 patientsResearch Published on 2021-01-132022-10-28 Journal: Annals of Intensive Care [Category] COVID-19, [키워드] association change Clinical outcome COVID-19 Critically ill critically ill patients CRP CRP level cytokine Day death detectable dosage exacerbated feature fibrinogen level groups ICU IL-1β IL-6 IL-6 level immuno-inflammatory increase in Inflammation Inflammatory response Lymphocyte count morbidity and mortality Mortality multicentre non-survivor Non-survivors not different Organ failure outcome paO2/fiO2 Patient plasma plasma biomarker positively correlated pro-inflammatory Prone position remained required responsible Result SARS Coronavirus SARS-CoV-2 SARS-CoV-2 patient severe respiratory disease severity significantly significantly higher SOFA score survival survivor symptom onset systemic immune response treated Ventilation worsening [DOI] 10.1186/s13613-020-00798-x PMC 바로가기 [Article Type] Research