The Association of Low Molecular Weight Heparin Use and In-hospital Mortality Among Patients Hospitalized with COVID-19Observational Study Published on 2022-02-012022-10-05 Journal: Cardiovascular Drugs and Therapy [Category] 임상, [키워드] 95% CI adjusted adjusted odds ratio age Analysis association benefit CHD conducted Coronary heart disease COVID-19 Critically ill D-dimer demonstrated determine diabetes Elderly patient enrolled had more heparin hospital hospitalized COVID-19 patients hypertension IL-6 in-hospital mortality in-hospital mortality rate Inflammatory cytokine IQR limit LMWH LMWH. low molecular weight median age men Mortality mortality risk Older parameter Patient patients with COVID-19 Primary outcome Retrospective study severe COVID-19 severely ill patients survival treated weight with COVID-19 Wuhan, China [DOI] 10.1007/s10557-020-07133-3 PMC 바로가기 [Article Type] Observational Study
Persistently elevated complement alternative pathway biomarkers in COVID-19 correlate with hypoxemia and predict in-hospital mortalityCOVID-19에서 지속적으로 상승된 보체 대체 경로 바이오마커는 저산소혈증과 상관관계가 있으며 병원 내 사망률을 예측합니다Article Published on 2022-02-012022-09-11 Journal: Medical Microbiology and Immunology [Category] COVID19(2023년), MERS, SARS, 바이오마커, [키워드] Activation Alternative pathway analyzed Biomarker C-reactive protein C5a cause complement Complement activation coronavirus disease Coronavirus disease 2019 correlations COVID-19 COVID-19 patient elevated enzyme enzyme-linked immunosorbent assays Evidence Factor Factor B ferritin healthy control healthy controls Hypoxemia ICU ICU admission IL-6 Immunity in-hospital mortality independent predictor Inflammatory response Innate Innate immunity lectin Level Lung disease marker measure Mortality Multi-organ damage overactivation pathway Patient patient sera predict prospectively studied quantified reduction Respiratory function risk SC5b-9 sera Serum level severely ill COVID-19 patients severity significantly sustained the patient [DOI] 10.1007/s00430-021-00725-2 PMC 바로가기 [Article Type] Article
Systemic administration of glucocorticoids, cardiovascular complications and mortality in patients hospitalised with COVID-19, SARS, MERS or influenza: A systematic review and meta-analysis of randomised trialsCOVID-19, SARS, MER 또는 인플루엔자로 입원 한 환자의 글루코 코르티코이드, 심혈관 합병증 및 사망률의 전신 투여 : 무작위 시험의 체계적인 검토 및 메타 분석Meta-Analysis Published on 2022-02-012022-09-10 Journal: Pharmacological research [Category] COVID19(2023년), MERS, SARS, 임상, [키워드] 95% CI administration all-cause mortality benefit cardiometabolic cardiovascular complication cardiovascular complications Confidence intervals COVID-19 Dexamethasone Effects estimate Follow-up glucocorticoid Glucocorticoids hospitalised in-hospital mortality Influenza lower mortality Mantel-Haenszel mechanical ventilation MERS Meta-analysis Mortality objective outcomes oxygen Patient patients Placebo random effect randomisation Randomised trial randomised trials receiving reduce reduce mortality reduced reduction renal function reported respiratory Respiratory Support respiratory viral infections Result risk severe COVID-19 significantly standard care Steroids subgroup subgroups systematic review systemic systemic glucocorticoid systemic glucocorticoids Treatment trials Viral was reduced were used with COVID-19 worsening [DOI] 10.1016/j.phrs.2021.106053 PMC 바로가기 [Article Type] Meta-Analysis
Prognostic role of Interleukin-6/lymphocytes ratio in SARS-CoV2 related pneumoniaSARS-CoV2 관련 폐렴에서 인터루킨-6/림프구 비율의 예후 역할Article Published on 2022-02-012022-09-11 Journal: International immunopharmacology [Category] COVID19(2023년), MERS, SARS, 바이오마커, [키워드] 95% CI Admission age analyzed AUC Biomarker C-reactive protein collected COVID-19 COVID-19 patient CRP cytokine Cytokine storm D-dimer defined died dimer discharged Endpoint females fibrinogen High flow nasal cannula highest Hospital admission Hospital mortality Hospital stay ICU IL-6 in-hospital mortality independent Intensive intensive care unit interleukin interleukin-6 intubation invasive ventilation lymphocyte Lymphocytes material mean value Mortality multivariate multivariate logistic regression N/L nasal nasal cannula neutrophil no difference outcome Patient Pneumonia Prognosis prognostic required Respiratory failure SARS-CoV2 severe respiratory failure significantly higher significantly lower study population suffered tested [DOI] 10.1016/j.intimp.2021.108435 PMC 바로가기 [Article Type] Article
Very Low Vitamin D Levels are a Strong Independent Predictor of Mortality in Hospitalized Patients with Severe COVID-19Research article Published on 2022-02-012022-10-05 Journal: Archives of medical research [Category] COVID19(2023년), SARS, 바이오마커, [키워드] 25-hydroxyvitamin D 95% CI Analysis association Biomarkers cohort study confounders COVID-19 deficiency defined global mortality greater Hospital admission Hospital stay Hospitalized Hypovitaminosis D In-hospital death in-hospital mortality independent Infection Length of hospital stay Level marker mechanical ventilation median Mortality outcome outcomes Patient patients Predictive prognostic biomarker remained Result risk SARS-CoV-2 serum 25-hydroxyvitamin D severe COVID-19 patients Severe COVID-19 pneumonia severe SARS-CoV-2 significantly Strong subject Vitamin D was reduced were measured [DOI] 10.1016/j.arcmed.2021.09.006 [Article Type] Research article
Impact of COVID-19 pandemic on acute heart failure admissions and mortality: a multicentre study (COV-HF-SIRIO 6 study)Multicenter Study Published on 2022-02-012023-07-07 Journal: ESC heart failure [Category] COVID19(2023년), [키워드] COVID-19 heart failure Hospitalization in-hospital mortality [DOI] 10.1002/ehf2.13680 PMC 바로가기 [Article Type] Multicenter Study
Effects of the COVID-19 pandemic on heart failure hospitalizations in Japan: interrupted time series analysisArticle Published on 2022-02-012023-07-07 Journal: ESC heart failure [Category] COVID19(2023년), [키워드] angiotensin II receptor blocker angiotensin-converting enzyme inhibitor Coronavirus disease 2019 heart failure in-hospital mortality [DOI] 10.1002/ehf2.13744 PMC 바로가기
Antibiotic Therapy in the Treatment of COVID-19 Pneumonia: Who and When?Article Published on 2022-01-312022-10-27 Journal: Antibiotics [Category] COVID-19, [키워드] 95% CI 95% confidence interval Accuracy adjusted odds ratio Admission age antibiotic Antibiotic therapy antibiotic use Antibiotics AUC Bacterial bacterial co-infection Bacterial infection Bacterial infections C-reactive protein Clinical outcome co-morbidity conducted COVID-19 COVID-19 pneumonia patient defined Deterioration diagnose Diagnosis diagnostic diarrhoea Effect empiric antibiotic evaluate evaluated had more hospitalised in-hospital mortality Infectious disease Inflammatory marker intensive care less moderate Mortality Observational cohort study Patient patients patients with COVID-19 Pneumonia presenting Prevent procalcitonin level receiving Sensitivity and specificity severe COVID-19 severity of COVID-19 similarity Singapore subsequent treated Treatment treatment for COVID-19 white cell with COVID-19 [DOI] 10.3390/antibiotics11020184 PMC 바로가기 [Article Type] Article
Neurological Prognostic Factors in Hospitalized Patients with COVID-19Article Published on 2022-01-302022-10-28 Journal: Brain Sciences [Category] COVID-19, [키워드] absence Admission clinical questionnaire cohort study Combination COVID-19 COVID-19 patient decreased mortality delirium Dizziness Factor fatigue headache Hospitalization in-hospital mortality increased the risk Infection interquartile range Male sex median age medical records neoplasm Neurological symptom Neurological symptoms NSS Older age Oxygen requirement Oxygen therapy Patient patients with COVID-19 patients with SARS-CoV-2 Poland predicted predictor Prognosis recruited risk SARS-COV-2 infection score Seizures stroke Symptom univariable analysis university with COVID-19 women [DOI] 10.3390/brainsci12020193 PMC 바로가기 [Article Type] Article
Lymphopenia as a Predictor for Adverse Clinical Outcomes in Hospitalized Patients with COVID-19: A Single Center Retrospective Study of 4485 CasesArticle Published on 2022-01-282022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] 95% CI 95% confidence interval Absolute lymphocyte count Admission Adverse adverse clinical outcomes adverse outcome adverse outcomes age center characteristic clinical clinical outcomes Comorbidities COVID-19 cubic spline determine dialysis expressed Gender hospital hospitalized COVID-19 patients ICU admission in-hospital mortality incidence increase in Invasive mechanical ventilation laboratory-confirmed Lymphocyte count lymphopenia Non-linear relationship Odds ratio outcome outcomes Patient patients with COVID-19 predict predictive power receiver operating characteristic curves restricted cubic splines retrospective risk was performed [DOI] 10.3390/jcm11030700 PMC 바로가기 [Article Type] Article