Inactivated COVID-19 vaccines: durability of Covaxin/BBV152 induced immunity against variants of concernArticle Published on 2022-09-172022-11-15 Journal: Journal of Travel Medicine [Category] SARS, 변종, 진단, 치료기술, [키워드] acute respiratory syndrome addition Antigen B cells B.1.1.529 B.1.1.7 B.1.351 B.1.617.2 baseline Beta binding binding antibodies binding antibody coronavirus country COVID-19 Delta elevated examined healthcare humoral immune response IgA IgA response IgG Immunity India induce Infection investigated limit of detection Lineage Month Neutralizing Neutralizing antibodies neutralizing antibody nucleocapsid omicron persistence SARS-CoV-2 SARS-CoV-2 variants SARS-CoV2 sustained the SARS-CoV-2 vaccination Vaccine variant variants of concern wild type Wuhan [DOI] 10.1093/jtm/taac088 PMC 바로가기
High Seroprevalence of SARS-CoV-2 in Mwanza, Northwestern Tanzania: A Population-Based SurveyArticle Published on 2022-09-162022-11-15 Journal: International Journal of Environmental Research an [Category] SARS, 진단, 치료기술, [키워드] African antibodies antibody blood sample cause Community conducted country COVID-19 cross-sectional survey Data analysis detect distribution enrolled Evidence Factors IgG IgG and IgM IgM and IgG interquartile range investigated loss of taste magnitude median age Mwanza occurred participant prevention protocol rapid test kit SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 IgM selected seropositive Seroprevalence survey Tanzania the SARS-CoV-2 the SARS-CoV-2 virus Transmission understanding was obtained were used [DOI] 10.3390/ijerph191811664 PMC 바로가기
Vitamin D Supplementation Does Not Influence SARS-CoV-2 Vaccine Efficacy or Immunogenicity: Sub-Studies Nested within the CORONAVIT Randomised Controlled TrialArticle Published on 2022-09-162022-11-15 Journal: Nutrients [Category] SARS, 진단, [키워드] 25-hydroxyvitamin D 95% CI Acute respiratory infection adjusted hazard ratio antibody baseline blood sample BNT162b2 BNT162b2 Pfizer boost Breakthrough SARS-CoV-2 infection cellular response ChAdOx1 nCoV-19 ChAdOx1 nCoV-19 Oxford–AstraZeneca circulating collected Concentration concentrations Controlled deficiency determine dose dried blood spot Effect Efficacy elevated Follow-up IFN-γ IgA IgG IgM influence interferon interferon gamma investigated mean difference neutralising antibody neutralising antibody titre of BNT162b2 offer participant Pfizer Protective randomised controlled randomised controlled trial reported response risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination SARS-CoV-2 vaccine significantly supernatant titre titres vaccination venous Vitamin Vitamin D Vitamin D status vitamin D supplement Vitamin D supplementation Whole blood [DOI] 10.3390/nu14183821 PMC 바로가기
Changes in the seroprevalence and risk factors between the first and second waves of COVID-19 in a metropolis in the Brazilian AmazonArticle Published on 2022-09-162022-11-15 Journal: Frontiers in Cellular and Infection Microbiology [Category] SARS, 진단, 치료기술, [키워드] acute respiratory syndrome affected age Amazon anti-SARS-CoV-2 antibody Belém Brazil change Characteristics circulation combating coronavirus coronavirus disease COVID-19 cross-sectional enzyme-linked immunosorbent Epidemic First wave Frequency group heterogeneous IgG IgG antibody increase in individual information lack measure pandemic performed Population Protective risk factor RStudio SARS-CoV-2 SARS-COV-2 infection second wave Seroepidemiology social isolation Spread statistical analysis virus was performed [DOI] 10.3389/fcimb.2022.932563 PMC 바로가기
Antibody titers among healthcare workers for coronavirus disease 2019 at 6 months after BNT162b2 vaccinationArticle Published on 2022-09-162022-11-15 Journal: Vaccine [Category] SARS, 진단, [키워드] acute respiratory syndrome age Analysis analyzed Anti-spike antibody antibody level Antibody titre BNT162b2 BNT162b2 vaccine Care conducted coronavirus disease coronavirus disease-2019 Coronavirus-2 COVID-19 decrease dose Factor female females healthcare healthcare worker Healthcare workers hospital IgG IgG antibody Japanese negative correlation participant Participants preserved Prospective Study Protein Regression SARS-CoV-2 side Side effects tested the vaccine vaccination were infected [DOI] 10.1016/j.vaccine.2022.08.035 PMC 바로가기
SARS-CoV-2 infection, vaccination, and antibody response trajectories in adults: a cohort study in CataloniaArticle Published on 2022-09-162022-11-15 Journal: BMC Medicine [Category] SARS, 진단, [키워드] Adults age Analysis antibody Antibody Response asymptomatic infection benefit booster dose Breakthrough infection cardiovascular diseases Characteristics cohort study Comorbidities COVID-19 COVID-19 testing COVID-19 vaccination COVID-19 vaccines determinants disease dose Electronic health record Host IgA IgG IgG level IgG RBD IgM IgM response immune response Immunity increase in infected individuals Infection janssen Kinetics less Mental mRNA vaccine multivariable nucleocapsid antigen occurred participant predicted prevalent RBD reflected Regression analyses response responses Result SARS-CoV-2 SARS-CoV-2 antibody responses SARS-COV-2 infection SARS-CoV-2 spike Sex smoking Sociodemographic characteristics statistically significant Support trajectory vaccination Vaccine was related [DOI] 10.1186/s12916-022-02547-2 PMC 바로가기
Frequency of positive antiphospholipid antibodies in pregnant women with SARS-CoV-2 infection and impact on pregnancy outcome: A single-center prospective study on 151 pregnanciesArticle Published on 2022-09-152022-11-15 Journal: Frontiers in Immunology [Category] SARS, 진단, [키워드] Admission anti-beta2glycoprotein I antibodies Anti-phospholipid antibodies anti-phospholipid syndrome antibodies antibody autoantibodies Causality checked Cohort collected Comorbidities Complication complications contributed COVID-19 de novo Department described diagnosed disorders elicited Frequency HELLP syndrome Hospitalized hypertensive ICU admission IgG IgM induce Infection information lack Lupus morbidity Nasopharyngeal swab Neonatal Obstetric occurred Occurrence pandemic pathogenic patients positive preeclampsia Pregnancy pregnancy morbidity. pregnant patient pregnant women Prospective Study raised remained required Research Risk factors SARS-CoV-2 SARS-COV-2 infection significantly single-center symptomatic SARS-CoV-2 infection the SARS-CoV-2 thrombosis titre women [DOI] 10.3389/fimmu.2022.953043 PMC 바로가기
Rapamycin and inulin for booster vaccine response stimulation (RIVASTIM)-rapamycin: study protocol for a randomised, controlled trial of immunosuppression modification with rapamycin to improve SARS-CoV-2 vaccine response in kidney transplant recipientsArticle Published on 2022-09-152022-11-15 Journal: Trials [Category] SARS, 진단, [키워드] 1:1 binding domain Booster vaccine cell-mediated response clinical Controlled trial COVID COVID-19 COVID-19 vaccination COVID-19 vaccine death develop disease severity dose Effectiveness Efficacy ENhance hospitalisation humoral hypothesise IgG immune cell population immunological Immunosuppression IMPROVE include increased risk Intervention kidney transplant recipient kidney transplant recipients Kidney transplantation live SARS-CoV-2 Modification mTOR inhibitor multicentre neutralisation New outcome participant Prednisolone Primary outcome proportion Protective protective immunity public health randomised randomised controlled trial Rapamycin recipient reduce reduced regimen registry responses SARS-CoV-2 SARS-CoV-2 vaccine secondary serological Sirolimus Standard of care Study protocol Tolerability Trial vaccination Vaccine vaccine response virus [DOI] 10.1186/s13063-022-06634-w PMC 바로가기
Isolation of a human SARS-CoV-2 neutralizing antibody from a synthetic phage library and its conversion to fluorescent biosensorsArticle Published on 2022-09-152022-11-15 Journal: Scientific Reports [Category] SARS, 진단, 치료기술, [키워드] acute respiratory syndrome addition angiotensin-converting enzyme 2 antibody antibody fragment antigen detection binding Clinical treatment clone coronavirus demonstrated diagnose effective Fab fluorescent Health help Human monoclonal antibody human SARS-CoV-2 IgG neutralize neutralizing antibody outbreak Prevent public health S protein S1 domain SARS-CoV-2 selected spike glycoprotein spread of COVID-19 viral infection viral infections virus detection [DOI] 10.1038/s41598-022-19699-z PMC 바로가기
SARS-CoV-2 specific T cell and humoral immune responses upon vaccination with BNT162b2: a 9 months longitudinal studyArticle Published on 2022-09-142022-11-15 Journal: Scientific Reports [Category] SARS, 진단, 치료기술, [키워드] acute respiratory syndrome BNT162b2 vaccine booster dose Cellular immune response changes in conducted coronavirus coronavirus disease COVID-19 demonstrated dose first vaccination follow-up period highest hospital humoral humoral immune response IgG IgG antibody immune response neutralization Neutralizing activity neutralizing antibody no correlation performed receiving SARS-CoV-2 SARS-CoV-2 neutralizing antibodies SARS-CoV-2 spike second vaccination serological Seven significantly sustained T cell T cell assay T cell response T cell responses the vaccine vaccination [DOI] 10.1038/s41598-022-19581-y PMC 바로가기